Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0012 | 0.0075 | 0.0106 |
Entamoeba histolytica | protein kinase, putative | 0.0098 | 0.1051 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0014 | 0.0106 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0155 | 0.0273 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0025 | 0.0229 | 0.0395 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0279 | 0.0226 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0054 | 0.0201 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.0123 | 0.0263 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0098 | 0.1051 | 0.7035 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0016 | 0.012 | 0.0154 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0016 | 0.0123 | 0.0459 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0012 | 0.0075 | 0.0021 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0279 | 0.113 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0315 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0315 | 0.0262 |
Schistosoma mansoni | ets-related | 0.0012 | 0.0075 | 0.0279 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | ewsr:fli fusion protein type | 0.0012 | 0.0075 | 0.0106 |
Trypanosoma cruzi | O-6 methyl-guanine alkyl transferase, putative | 0.0134 | 0.1458 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0106 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.1045 | 0.2598 |
Entamoeba histolytica | protein kinase, putative | 0.0098 | 0.1051 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0016 | 0.0123 | 0.0347 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0016 | 0.012 | 0.0154 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0016 | 0.012 | 0.0249 |
Schistosoma mansoni | elf1 | 0.0012 | 0.0075 | 0.0279 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0016 | 0.012 | 0.0154 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | Cytochrome P450 family protein | 0.0016 | 0.012 | 0.025 |
Echinococcus granulosus | ETS domain containing protein Elk 1 | 0.0012 | 0.0075 | 0.0106 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0712 | 0.1728 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0098 | 0.1051 | 1 |
Trypanosoma cruzi | O-6 methyl-guanine alkyl transferase, putative | 0.0134 | 0.1458 | 1 |
Echinococcus multilocularis | ewsr:fli fusion protein type | 0.0012 | 0.0075 | 0.0021 |
Brugia malayi | Uncoordinated protein 44 | 0.0016 | 0.0123 | 0.026 |
Mycobacterium ulcerans | methylated-DNA--protein-cysteine methyltransferase Ogt | 0.0407 | 0.4545 | 1 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0016 | 0.012 | 0.0249 |
Loa Loa (eye worm) | fli-1 protein | 0.0241 | 0.2671 | 0.6845 |
Brugia malayi | Protein kinase domain containing protein | 0.0098 | 0.1051 | 0.3617 |
Echinococcus granulosus | protein C ets 2 | 0.0012 | 0.0075 | 0.0106 |
Echinococcus granulosus | lamin | 0.003 | 0.0279 | 0.113 |
Loa Loa (eye worm) | cytochrome P450 | 0.0016 | 0.012 | 0.0181 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0012 | 0.0075 | 0.0106 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0098 | 0.1051 | 0.3936 |
Chlamydia trachomatis | methylated-DNA protein-cysteine methyltransferase | 0.0134 | 0.1458 | 0.5 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0054 | 0.0201 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0121 | 0.3851 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0315 | 0.0262 |
Echinococcus multilocularis | ets variant gene 4 | 0.0012 | 0.0075 | 0.0021 |
Echinococcus multilocularis | ETS domain containing protein Elk 1 | 0.0012 | 0.0075 | 0.0021 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0036 | 0.0356 | 0.0799 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0012 | 0.0075 | 0.0062 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0229 | 0.0643 |
Onchocerca volvulus | 0.026 | 0.2883 | 1 | |
Onchocerca volvulus | 0.003 | 0.0279 | 0.0805 | |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0054 | 0.0007 |
Echinococcus granulosus | ETS transcription factor Elf 1 | 0.0012 | 0.0075 | 0.0106 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | geminin | 0.0186 | 0.2046 | 1 |
Schistosoma mansoni | netrin receptor unc5 | 0.0016 | 0.0123 | 0.0459 |
Leishmania major | cytochrome p450-like protein | 0.0025 | 0.0229 | 0.1041 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0016 | 0.012 | 0.0154 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0023 | 0.0209 | 0.0559 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0098 | 0.1051 | 0.7035 |
Brugia malayi | Ets-domain containing protein | 0.0012 | 0.0075 | 0.0086 |
Echinococcus granulosus | ETS transcription factor Elf 5 | 0.0012 | 0.0075 | 0.0106 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0016 | 0.0123 | 0.0188 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0053 | 0.0006 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0279 | 0.1044 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0012 | 0.0086 | 0.0123 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.001 | 0.0054 | 1 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0016 | 0.012 | 0.0354 |
Brugia malayi | DNA-binding protein D-ETS-3 | 0.0012 | 0.0075 | 0.0086 |
Brugia malayi | Pre-SET motif family protein | 0.0228 | 0.2525 | 0.8947 |
Entamoeba histolytica | hypothetical protein | 0.0098 | 0.1051 | 1 |
Brugia malayi | Ets-domain containing protein | 0.0079 | 0.0842 | 0.2862 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0124 | 0.0192 |
Trichomonas vaginalis | set domain proteins, putative | 0.026 | 0.2882 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0098 | 0.1051 | 0.7035 |
Trichomonas vaginalis | methylated-DNA--protein-cysteine methyltransferase, putative | 0.0134 | 0.1458 | 0.4971 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0016 | 0.012 | 0.0154 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0016 | 0.012 | 0.0249 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0016 | 0.012 | 0.0154 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0098 | 0.1051 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0273 | 0.058 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0315 | 0.0689 |
Schistosoma mansoni | lamin | 0.003 | 0.0279 | 0.1044 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0315 | 0.1178 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | Ankyrin | 0.0016 | 0.0124 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0123 | 0.0188 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.2046 | 0.766 |
Schistosoma mansoni | cytochrome P450 | 0.0016 | 0.012 | 0.0449 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0123 | 0.0459 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0081 | 0.0858 | 0.0808 |
Echinococcus multilocularis | protein C ets 2 | 0.0012 | 0.0075 | 0.0021 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0016 | 0.0123 | 0.0347 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium leprae | PROBABLE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE OGT (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA | 0.0407 | 0.4545 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0279 | 0.0596 |
Echinococcus granulosus | death domain containing protein | 0.0016 | 0.0123 | 0.0347 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | Protein kinase domain containing protein | 0.0016 | 0.0128 | 0.028 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0279 | 0.0824 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0315 | 0.1178 |
Echinococcus granulosus | bloom syndrome protein | 0.0023 | 0.0209 | 0.078 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0301 | 0.1242 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0079 | 0.0842 | 0.2068 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0023 | 0.0209 | 0.0572 |
Schistosoma mansoni | gabp alpha | 0.0079 | 0.0842 | 0.3154 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0054 | 0.001 |
Echinococcus multilocularis | musashi | 0.003 | 0.0279 | 0.0226 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0279 | 0.0596 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0025 | 0.0229 | 0.1041 |
Loa Loa (eye worm) | RecQ helicase | 0.0023 | 0.0209 | 0.0413 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0229 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.0348 | 0.3878 | 1 |
Brugia malayi | Ets-domain containing protein | 0.0079 | 0.0842 | 0.2862 |
Brugia malayi | Fli-1 protein | 0.0241 | 0.2671 | 0.9473 |
Entamoeba histolytica | recQ family helicase, putative | 0.0012 | 0.0086 | 0.0815 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0054 | 0.056 | 0.4912 |
Loa Loa (eye worm) | D-ets-2 protein | 0.0012 | 0.0075 | 0.0062 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0098 | 0.1051 | 0.2613 |
Echinococcus multilocularis | 0.0016 | 0.012 | 0.0067 | |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0254 | 0.2816 | 0.7226 |
Echinococcus multilocularis | bloom syndrome protein | 0.0023 | 0.0209 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0075 | 0.0062 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0014 | 0.0106 | 0.0262 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0018 | 0.0153 | 0.0574 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0054 | 0.001 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0279 | 0.0824 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0016 | 0.012 | 0.0154 |
Leishmania major | cytochrome p450-like protein | 0.0016 | 0.012 | 0.0249 |
Schistosoma mansoni | ets | 0.0012 | 0.0075 | 0.0279 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0016 | 0.0123 | 0.026 |
Leishmania major | cytochrome p450-like protein | 0.0016 | 0.012 | 0.0249 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0016 | 0.012 | 0.0333 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0229 | 0.0464 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0315 | 0.0954 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0016 | 0.012 | 0.0154 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0016 | 0.0124 | 0.0465 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0054 | 0.1703 |
Echinococcus multilocularis | dual specificity | 0.0098 | 0.1051 | 0.1003 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0023 | 0.0209 | 0.0559 |
Schistosoma mansoni | lamin | 0.003 | 0.0279 | 0.1044 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0081 | 0.0858 | 0.4036 |
Onchocerca volvulus | Netrin receptor homolog | 0.0016 | 0.0123 | 0.0254 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0123 | 0.019 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0315 | 0.1178 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0315 | 0.1178 |
Echinococcus multilocularis | ETS transcription factor Elf 5 | 0.0012 | 0.0075 | 0.0021 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0025 | 0.0229 | 0.1041 |
Brugia malayi | Death domain containing protein | 0.0016 | 0.0123 | 0.026 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | follicle stimulating hormone receptor | 0.0254 | 0.2816 | 1 |
Treponema pallidum | methylated-DNA-protein-cysteine S-methyltransferase (dat) | 0.0134 | 0.1458 | 0.5 |
Onchocerca volvulus | 0.0033 | 0.0315 | 0.0931 | |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0016 | 0.012 | 0.3811 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0016 | 0.0123 | 0.0069 |
Loa Loa (eye worm) | ets-domain-containing protein | 0.0012 | 0.0075 | 0.0062 |
Trypanosoma brucei | cytochrome P450, putative | 0.0025 | 0.0229 | 0.1479 |
Mycobacterium ulcerans | DNA-methyltransferase (modification methylase) | 0.0054 | 0.056 | 0.1133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0075 | 0.0062 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0315 | 0.131 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0007 |
Mycobacterium tuberculosis | Methylated-DNA--protein-cysteine methyltransferase Ogt (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltra | 0.0407 | 0.4545 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.01 | 0.0128 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0177 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.2046 | 0.766 |
Loa Loa (eye worm) | DNA-binding protein D-ETS-3 | 0.0012 | 0.0075 | 0.0062 |
Echinococcus multilocularis | Ankyrin | 0.0016 | 0.0124 | 0.0071 |
Echinococcus multilocularis | ETS transcription factor Elf 1 | 0.0012 | 0.0075 | 0.0021 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0016 | 0.012 | 0.0154 |
Echinococcus multilocularis | lamin | 0.003 | 0.0279 | 0.0226 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0079 | 0.0842 | 0.0793 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0279 | 0.0596 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0025 | 0.0229 | 0.0464 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0075 | 0.0279 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0016 | 0.0123 | 0.0069 |
Echinococcus multilocularis | geminin | 0.0186 | 0.2046 | 0.2003 |
Brugia malayi | hypothetical protein | 0.0133 | 0.1454 | 0.5073 |
Echinococcus granulosus | dual specificity | 0.0098 | 0.1051 | 0.5007 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.012 | 0.0449 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0075 | 0.0279 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0079 | 0.0842 | 0.396 |
Brugia malayi | cytochrome P450 | 0.0016 | 0.012 | 0.025 |
Schistosoma mansoni | polyomavirus enhancer activator 3 pea3 | 0.0012 | 0.0075 | 0.0279 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0054 | 0.1703 |
Brugia malayi | Cytochrome P450 family protein | 0.0036 | 0.0356 | 0.1105 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0228 | 0.2525 | 0.6465 |
Brugia malayi | transcription factor E74 isoform | 0.0012 | 0.0075 | 0.0086 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0229 | 0.0464 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0016 | 0.012 | 0.0249 |
Leishmania major | hypothetical protein, conserved | 0.0134 | 0.1458 | 1 |
Schistosoma mansoni | ets-related | 0.0241 | 0.2671 | 1 |
Onchocerca volvulus | 0.003 | 0.0279 | 0.0805 | |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.01 | 0.0128 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0012 | 0.0075 | 0.0021 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0279 | 0.113 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0315 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.1045 | 0.2598 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CGI (functional) | 0 uM | Lowest concentration at which the effect on HeLa cell colony formation became apparent; d denotes Not tested | ChEMBL. | 3018241 |
ID50 (functional) | = 0.25 uM | Concentration required to reduce Rhino virus type 64 induced plaque formation in HeLa cell culture to 50% of control | ChEMBL. | 3018241 |
ID50 (functional) | = 1.42 uM | Concentration required to reduce Rhino virus type 1A induced plaque formation in HeLa cell culture to 50% of control | ChEMBL. | 3018241 |
ID50 (functional) | = 1.42 uM | Concentration required to reduce Rhino virus type 9 induced plaque formation in HeLa cell culture to 50% of control | ChEMBL. | 3018241 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.