Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Onchocerca volvulus | 0.0282 | 1 | 1 | |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0282 | 1 | 1 |
Onchocerca volvulus | 0.0282 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0282 | 1 | 1 |
Onchocerca volvulus | 0.0082 | 0.2192 | 0.2192 | |
Brugia malayi | Muscleblind-like protein | 0.0152 | 0.4925 | 0.4925 |
Echinococcus multilocularis | aldo keto reductase | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0282 | 1 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0282 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0282 | 1 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.02 | 0.6816 | 0.5922 |
Echinococcus granulosus | aldo keto reductase | 0.0282 | 1 | 1 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0082 | 0.2192 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0282 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Onchocerca volvulus | 0.0282 | 1 | 1 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0282 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0282 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0282 | 1 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0152 | 0.4925 | 0.4925 |
Onchocerca volvulus | 0.0282 | 1 | 1 | |
Brugia malayi | NADH-dependent xylose reductase | 0.0082 | 0.2192 | 0.2192 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0282 | 1 | 1 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0082 | 0.2192 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0282 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.4925 | 0.4925 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0282 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0282 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0282 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0282 | 1 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0282 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0082 | 0.2192 | 0.2192 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0282 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.082 | 0.082 |
Schistosoma mansoni | pol-related | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0282 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0282 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.082 | 0.082 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Echinococcus granulosus | aldehyde reductase | 0.02 | 0.6816 | 0.6816 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0282 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0282 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.082 | 0.082 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0082 | 0.2192 | 0.2192 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.082 | 0.082 |
Echinococcus multilocularis | muscleblind protein | 0.0152 | 0.4925 | 0.4925 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0082 | 0.2192 | 0.5 |
Plasmodium vivax | aldehyde reductase, putative | 0.0082 | 0.2192 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.082 | 0.082 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.082 | 0.082 |
Echinococcus granulosus | hypothetical protein | 0.0282 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0282 | 1 | 1 |
Onchocerca volvulus | 0.0282 | 1 | 1 | |
Echinococcus multilocularis | aldehyde reductase | 0.02 | 0.6816 | 0.6816 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0282 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0282 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0282 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0282 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0282 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0282 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0282 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0282 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0282 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0082 | 0.2192 | 0.2192 |
Schistosoma mansoni | potassium channel beta | 0.0082 | 0.2192 | 0.2192 |
Echinococcus granulosus | muscleblind protein | 0.0152 | 0.4925 | 0.4925 |
Entamoeba histolytica | aldose reductase, putative | 0.0282 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0282 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0282 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.082 | 0.082 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0082 | 0.2192 | 0.2192 |
Onchocerca volvulus | 0.0282 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.4925 | 0.4925 |
Toxoplasma gondii | aldose reductase, putative | 0.0282 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0282 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0282 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0282 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0282 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.082 | 0.082 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0282 | 1 | 1 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0082 | 0.2192 | 0.2192 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.082 | 0.082 |
Entamoeba histolytica | aldose reductase, putative | 0.0282 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.