Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0113 | 0.2356 | 0.2985 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0113 | 0.2356 | 0.4954 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0472 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.1371 | 0.2882 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.005 | 0.0697 | 0.0697 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0039 | 0.041 | 0.0502 |
Schistosoma mansoni | hypothetical protein | 0.0402 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.005 | 0.0697 | 0.1464 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0263 | 0.0553 |
Echinococcus granulosus | tar DNA binding protein | 0.0125 | 0.2668 | 0.2668 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3051 | 0.6414 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.005 | 0.0697 | 0.1464 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.005 | 0.0697 | 0.0697 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0039 | 0.041 | 0.0862 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.005 | 0.0697 | 0.1464 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0041 | 0.0472 | 0.0589 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.0266 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0697 | 0.1464 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.005 | 0.0697 | 0.0697 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0342 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0039 | 0.041 | 0.0502 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0039 | 0.041 | 0.041 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0566 | 0.0566 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0039 | 0.041 | 0.5 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0039 | 0.041 | 0.0502 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0566 | 0.119 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0697 | 0.1464 |
Brugia malayi | Bromodomain containing protein | 0.0149 | 0.3316 | 0.6971 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.005 | 0.0697 | 0.1464 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.005 | 0.0697 | 0.0697 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0039 | 0.041 | 0.0502 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0266 | 0.0266 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.041 | 0.0502 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0697 | 0.1464 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0119 | 0.2521 | 0.2521 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0113 | 0.2356 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.2668 | 0.2668 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0317 | 0.0317 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0039 | 0.041 | 0.0502 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.005 | 0.0697 | 0.0697 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.3609 | 0.3609 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0039 | 0.041 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0257 | 0.6172 | 0.8837 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0034 | 0.0264 | 0.0264 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0039 | 0.041 | 0.0502 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0075 | 0.0157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.005 | 0.0697 | 0.1464 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.005 | 0.0697 | 0.1464 |
Echinococcus multilocularis | FTZ F1 alpha | 0.005 | 0.0697 | 0.0697 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0039 | 0.041 | 0.0502 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.005 | 0.0697 | 0.1464 |
Plasmodium falciparum | glutathione reductase | 0.0113 | 0.2356 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0566 | 0.0566 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0173 | 0.0173 |
Loa Loa (eye worm) | TAR-binding protein | 0.0125 | 0.2668 | 0.5609 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0342 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0139 | 0.3061 | 0.4232 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0317 | 0.0666 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.005 | 0.0697 | 0.1464 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0342 | 0.0342 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.005 | 0.0697 | 0.1464 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.4757 | 1 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0039 | 0.041 | 0.0502 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0039 | 0.041 | 0.0502 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0026 | 0.0075 | 0.0157 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.045 | 0.045 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0317 | 0.0371 |
Schistosoma mansoni | thyroid hormone receptor | 0.005 | 0.0697 | 0.0697 |
Trypanosoma brucei | trypanothione reductase | 0.0113 | 0.2356 | 0.3241 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0697 | 0.1464 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0342 | 0.0719 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0163 | 0.0163 |
Brugia malayi | nuclear receptor RXR | 0.0026 | 0.0075 | 0.0157 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.016 | 0.3609 | 0.7587 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.005 | 0.0697 | 0.1464 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.005 | 0.0697 | 0.1464 |
Echinococcus multilocularis | tar DNA binding protein | 0.0125 | 0.2668 | 0.2668 |
Onchocerca volvulus | 0.0232 | 0.5498 | 1 | |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0124 | 0.026 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0163 | 0.0163 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.005 | 0.0697 | 0.1464 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.005 | 0.0697 | 0.1464 |
Leishmania major | trypanothione reductase | 0.0113 | 0.2356 | 0.3241 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.005 | 0.0697 | 0.0697 |
Trypanosoma cruzi | ISWI complex protein | 0.003 | 0.0173 | 0.0168 |
Echinococcus granulosus | FTZ F1 alpha | 0.005 | 0.0697 | 0.0697 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0075 | 0.0157 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.005 | 0.0697 | 0.0697 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0039 | 0.041 | 0.1549 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0566 | 0.0566 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0039 | 0.041 | 0.1549 |
Treponema pallidum | NADH oxidase | 0.0039 | 0.041 | 0.5 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0039 | 0.041 | 0.0502 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0039 | 0.041 | 0.018 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0039 | 0.041 | 0.041 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.005 | 0.0697 | 0.0697 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0029 | 0.0136 | 0.0286 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0026 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0697 | 0.1464 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.005 | 0.0697 | 0.0697 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0039 | 0.041 | 0.0502 |
Echinococcus multilocularis | geminin | 0.0333 | 0.8179 | 0.8179 |
Schistosoma mansoni | hypothetical protein | 0.0333 | 0.8179 | 0.8179 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0342 | 0.0342 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0673 | 0.1414 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0472 | 0.0589 |
Onchocerca volvulus | 0.0028 | 0.0124 | 0.0225 | |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0317 | 0.0666 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1494 | 0.314 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0039 | 0.041 | 0.0502 |
Trypanosoma brucei | ISWI complex protein | 0.003 | 0.0173 | 0.0168 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0113 | 0.2356 | 0.3241 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0063 | 0.1049 | 0.1049 |
Brugia malayi | Thioredoxin reductase | 0.0113 | 0.2356 | 0.4954 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0041 | 0.0472 | 0.0589 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0257 | 0.6172 | 0.8837 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1636 | 0.3438 |
Echinococcus granulosus | zinc finger protein | 0.004 | 0.0437 | 0.0437 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0317 | 0.0317 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.005 | 0.0697 | 0.1464 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0566 | 0.0566 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.016 | 0.3609 | 0.7587 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.005 | 0.0697 | 0.0697 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.005 | 0.0697 | 0.1464 |
Onchocerca volvulus | Bile acid receptor homolog | 0.005 | 0.0697 | 0.1267 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0673 | 0.1414 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0317 | 0.0371 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0163 | 0.0478 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0317 | 0.1144 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0566 | 0.0566 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0039 | 0.041 | 0.1549 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.2668 | 0.2668 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0075 | 0.0157 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0026 | 0.0075 | 0.0075 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.302 | 0.302 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0075 | 0.0157 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0114 | 0.2396 | 0.2396 |
Trypanosoma cruzi | ISWI complex protein | 0.003 | 0.0173 | 0.0168 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0119 | 0.2521 | 0.2521 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0673 | 0.1414 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0342 | 0.0342 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.005 | 0.0697 | 0.0697 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0034 | 0.0264 | 0.0264 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.005 | 0.0697 | 0.0697 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.005 | 0.0697 | 0.0697 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.005 | 0.0697 | 0.0697 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0139 | 0.3061 | 0.4232 |
Brugia malayi | glutathione reductase | 0.0113 | 0.2356 | 0.4954 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.0266 | 0.0266 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0257 | 0.6172 | 0.8837 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0026 | 0.0075 | 0.0157 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0046 | 0.0591 | 0.0591 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0124 | 0.0124 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0257 | 0.6172 | 0.8837 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0988 | 0.0988 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0029 | 0.0136 | 0.0286 |
Brugia malayi | nuclear receptor NHR-88 | 0.005 | 0.0697 | 0.1464 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.005 | 0.0697 | 0.0697 |
Schistosoma mansoni | thyroid hormone receptor | 0.005 | 0.0697 | 0.0697 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0026 | 0.0075 | 0.0157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.005 | 0.0697 | 0.1464 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.005 | 0.0697 | 0.0697 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.005 | 0.0697 | 0.0697 |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.041 | 0.1549 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0075 | 0.0157 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.302 | 0.302 |
Brugia malayi | nuclear hormone receptor | 0.005 | 0.0697 | 0.1464 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0039 | 0.041 | 0.0502 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.005 | 0.0697 | 0.1267 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0295 | 0.716 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0566 | 0.119 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0114 | 0.2396 | 0.2396 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0053 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0053 | 0.0112 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.005 | 0.0697 | 0.1464 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0697 | 0.1464 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0566 | 0.0566 |
Brugia malayi | steroid hormone receptor | 0.005 | 0.0697 | 0.1464 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0263 | 0.0263 |
Schistosoma mansoni | coup transcription factor | 0.005 | 0.0697 | 0.0697 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.2668 | 0.2668 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0026 | 0.0075 | 0.0075 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0342 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0266 | 0.0266 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.005 | 0.0697 | 0.1464 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0139 | 0.3061 | 0.4232 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.005 | 0.0697 | 0.0697 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0163 | 0.0478 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.005 | 0.0697 | 0.1464 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.005 | 0.0697 | 0.1464 |
Mycobacterium ulcerans | hypothetical protein | 0.0155 | 0.3477 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.005 | 0.0697 | 0.1464 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0039 | 0.041 | 0.018 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0633 | 0.2517 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.005 | 0.0697 | 0.0697 |
Plasmodium vivax | glutathione reductase, putative | 0.0113 | 0.2356 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0942 | 0.3859 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0075 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0697 | 0.1464 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0566 | 0.0566 |
Schistosoma mansoni | zinc finger protein | 0.004 | 0.0437 | 0.0437 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0402 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0039 | 0.041 | 0.5 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0039 | 0.041 | 0.0502 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.2668 | 0.2668 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.005 | 0.0697 | 0.0697 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0063 | 0.1049 | 0.1049 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0041 | 0.045 | 0.0945 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0071 | 0.1244 | 0.1244 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.005 | 0.0697 | 0.0697 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.2668 | 0.2668 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0119 | 0.0119 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0317 | 0.0317 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0034 | 0.0264 | 0.0264 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0124 | 0.026 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.5498 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0126 | 0.2707 | 0.2707 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0342 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0113 | 0.2356 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0155 | 0.3477 | 0.4704 |
Schistosoma mansoni | nuclear hormone receptor | 0.005 | 0.0697 | 0.0697 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.4757 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0046 | 0.0591 | 0.0591 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0039 | 0.041 | 0.1549 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.1049 | 0.1049 |
Loa Loa (eye worm) | steroid hormone receptor | 0.005 | 0.0697 | 0.1464 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0163 | 0.0163 |
Brugia malayi | ecdysteroid receptor | 0.005 | 0.0697 | 0.1464 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.005 | 0.0697 | 0.1464 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.1367 | 0.2874 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0317 | 0.0371 |
Echinococcus multilocularis | zinc finger protein | 0.004 | 0.0437 | 0.0437 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.005 | 0.0697 | 0.0697 |
Mycobacterium tuberculosis | Probable reductase | 0.0257 | 0.6172 | 0.8837 |
Onchocerca volvulus | 0.003 | 0.0163 | 0.0297 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0295 | 0.716 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0295 | 0.716 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0039 | 0.041 | 0.1549 |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.041 | 0.1549 |
Schistosoma mansoni | zinc finger protein | 0.003 | 0.0173 | 0.0173 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.005 | 0.0697 | 0.0697 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.1049 | 0.1049 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.005 | 0.0697 | 0.1267 |
Leishmania major | hypothetical protein, conserved | 0.003 | 0.0173 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1049 | 0.2206 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0286 | 0.693 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0039 | 0.041 | 0.0502 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0163 | 0.0344 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.005 | 0.0697 | 0.1464 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.3609 | 0.3609 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.005 | 0.0697 | 0.0697 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0125 | 0.2668 | 0.5609 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0035 | 0.0296 | 0.0621 |
Brugia malayi | PHD-finger family protein | 0.0051 | 0.0714 | 0.1502 |
Onchocerca volvulus | 0.0093 | 0.1825 | 0.332 | |
Loa Loa (eye worm) | glutathione reductase | 0.0113 | 0.2356 | 0.4954 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0075 | 0.0157 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0039 | 0.041 | 0.1549 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0317 | 0.0371 |
Brugia malayi | RNA binding protein | 0.0125 | 0.2668 | 0.5609 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0071 | 0.1244 | 0.1244 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0673 | 0.1414 |
Brugia malayi | TAR-binding protein | 0.0125 | 0.2668 | 0.5609 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0046 | 0.0591 | 0.0591 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0263 | 0.0553 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0039 | 0.041 | 0.0502 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0039 | 0.041 | 0.041 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0286 | 0.693 | 1 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0039 | 0.041 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0333 | 0.8179 | 0.8179 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0697 | 0.1464 |
Loa Loa (eye worm) | RNA binding protein | 0.0125 | 0.2668 | 0.5609 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0125 | 0.2668 | 0.5609 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0342 | 0.0342 |
Toxoplasma gondii | thioredoxin reductase | 0.0113 | 0.2356 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.005 | 0.0697 | 0.0697 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0257 | 0.6172 | 0.8837 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0286 | 0.693 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0286 | 0.693 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0026 | 0.0075 | 0.0075 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0295 | 0.716 | 1 |
Echinococcus granulosus | geminin | 0.0333 | 0.8179 | 0.8179 |
Onchocerca volvulus | 0.005 | 0.0697 | 0.1267 | |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.016 | 0.3609 | 0.3609 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0034 | 0.0264 | 0.0264 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0712 | 0.0926 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.