Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0026 | 0.0153 | 0.0602 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0069 | 0.1063 | 0.9034 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0675 | 0.1472 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0187 | 0.3551 | 0.7548 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.004 | 0.0454 | 0.339 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0407 | 0.0407 |
Loa Loa (eye worm) | TAR-binding protein | 0.0191 | 0.3638 | 1 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0026 | 0.0153 | 0.0333 |
Schistosoma mansoni | tar DNA-binding protein | 0.0191 | 0.3638 | 0.7933 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0387 | 0.0387 |
Echinococcus multilocularis | pyruvate kinase | 0.0035 | 0.0358 | 0.0358 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0069 | 0.1063 | 0.2125 |
Plasmodium falciparum | glutathione reductase | 0.0026 | 0.0153 | 0.0602 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0069 | 0.1063 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0675 | 0.1856 |
Giardia lamblia | Pyruvate kinase | 0.0069 | 0.1063 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0026 | 0.0153 | 0.0153 |
Echinococcus multilocularis | tar DNA binding protein | 0.0191 | 0.3638 | 0.3638 |
Onchocerca volvulus | 0.0038 | 0.0407 | 0.383 | |
Trichomonas vaginalis | mercuric reductase, putative | 0.0026 | 0.0153 | 0.0667 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0407 | 0.0696 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0026 | 0.0153 | 0.0602 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0026 | 0.0153 | 0.0602 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0187 | 0.3551 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0143 | 0.2617 | 0.7193 |
Schistosoma mansoni | ap endonuclease | 0.0023 | 0.0088 | 0.0191 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0219 | 0.0603 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.1063 | 0.2922 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0169 | 0.3155 | 0.6687 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0407 | 0.0696 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.3343 | 0.729 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.004 | 0.0454 | 0.0454 |
Echinococcus multilocularis | pyruvate kinase | 0.0035 | 0.0358 | 0.0358 |
Chlamydia trachomatis | pyruvate kinase | 0.0069 | 0.1063 | 1 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0026 | 0.0153 | 0.0667 |
Brugia malayi | Latrophilin receptor protein 2 | 0.005 | 0.0675 | 0.1856 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0407 | 0.0696 |
Schistosoma mansoni | tar DNA-binding protein | 0.0191 | 0.3638 | 0.7933 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0074 | 0.1167 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0477 | 0.1313 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0109 | 0.1906 | 0.5238 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0026 | 0.0153 | 0.042 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0456 | 0.0456 |
Echinococcus multilocularis | pyruvate kinase | 0.0069 | 0.1063 | 0.1063 |
Loa Loa (eye worm) | RNA binding protein | 0.0191 | 0.3638 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0191 | 0.3638 | 1 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0019 | 0.001 | 0.0028 |
Schistosoma mansoni | tar DNA-binding protein | 0.0191 | 0.3638 | 0.7933 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0191 | 0.3638 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0169 | 0.3155 | 0.6687 |
Echinococcus multilocularis | pyruvate kinase | 0.0069 | 0.1063 | 0.1063 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0494 | 1 | 1 |
Leishmania major | pyruvate kinase | 0.0069 | 0.1063 | 0.9034 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0026 | 0.0153 | 0.0602 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0169 | 0.3155 | 0.6687 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0625 | 0.1717 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0075 | 0.1188 | 0.1188 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0026 | 0.0153 | 0.0602 |
Loa Loa (eye worm) | pyruvate kinase | 0.0069 | 0.1063 | 0.2922 |
Plasmodium falciparum | pyruvate kinase | 0.0069 | 0.1063 | 0.9034 |
Echinococcus granulosus | pyruvate kinase | 0.0069 | 0.1063 | 0.1063 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0376 | 0.0376 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0026 | 0.0153 | 0.0142 |
Schistosoma mansoni | hypothetical protein | 0.0109 | 0.1906 | 0.4155 |
Schistosoma mansoni | pyruvate kinase | 0.0069 | 0.1063 | 0.2318 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0407 | 0.3274 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0407 | 0.1119 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1906 | 0.5238 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.027 | 0.027 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0219 | 0.122 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0026 | 0.0153 | 0.0602 |
Schistosoma mansoni | tar DNA-binding protein | 0.0191 | 0.3638 | 0.7933 |
Echinococcus granulosus | peregrin | 0.0031 | 0.027 | 0.027 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.027 | 0.0741 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.0021 | 0.0053 | 0.0146 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0143 | 0.2617 | 0.7193 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0407 | 0.1119 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0376 | 0.0376 |
Brugia malayi | RNA binding protein | 0.0191 | 0.3638 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0454 | 0.339 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0407 | 0.2958 |
Leishmania major | trypanothione reductase | 0.0074 | 0.1167 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0052 | 0.0142 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0407 | 0.0696 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.005 | 0.0675 | 0.1856 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.004 | 0.0454 | 0.3753 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0029 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0427 | 0.1175 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0026 | 0.0153 | 0.0602 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0069 | 0.1063 | 1 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0219 | 0.1351 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0029 | 0.0029 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.1188 | 0.2591 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0407 | 0.0696 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0026 | 0.0153 | 0.0602 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0026 | 0.0153 | 0.0602 |
Schistosoma mansoni | ap endonuclease | 0.0023 | 0.0088 | 0.0191 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0187 | 0.3551 | 0.7548 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0026 | 0.0153 | 0.0602 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0407 | 0.0696 |
Echinococcus granulosus | tar DNA binding protein | 0.0191 | 0.3638 | 0.3638 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0069 | 0.1063 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0026 | 0.0153 | 0.0602 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0407 | 0.1119 |
Echinococcus multilocularis | pyruvate kinase | 0.0054 | 0.0758 | 0.0758 |
Echinococcus granulosus | GPCR family 2 | 0.005 | 0.0675 | 0.0675 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0069 | 0.1063 | 0.9034 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.005 | 0.0675 | 0.0675 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0069 | 0.1063 | 0.2922 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0052 | 0.0113 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0069 | 0.1063 | 0.9034 |
Loa Loa (eye worm) | pyruvate kinase | 0.0069 | 0.1063 | 0.2922 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0019 | 0.001 | 0.0028 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.005 | 0.0675 | 0.1856 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0407 | 0.0888 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0407 | 0.2958 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0407 | 0.3274 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0494 | 1 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.004 | 0.0454 | 0.3753 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0219 | 0.2065 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0094 | 0.1595 | 0.1595 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0407 | 0.1119 |
Plasmodium vivax | pyruvate kinase, putative | 0.0069 | 0.1063 | 0.9034 |
Mycobacterium ulcerans | pyruvate kinase | 0.0069 | 0.1063 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.005 | 0.0675 | 0.0675 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0023 | 0.0088 | 0.0241 |
Brugia malayi | jmjC domain containing protein | 0.0094 | 0.1595 | 0.4385 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.016 | 0.2966 | 0.8153 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0454 | 0.339 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0026 | 0.0153 | 0.0667 |
Onchocerca volvulus | 0.0038 | 0.0407 | 0.383 | |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.004 | 0.0454 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0169 | 0.3155 | 0.8759 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0407 | 0.2958 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0387 | 0.0844 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.004 | 0.0454 | 0.0454 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0407 | 0.3274 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0026 | 0.0153 | 0.0602 |
Leishmania major | pyruvate kinase | 0.0069 | 0.1063 | 0.9034 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0092 | 0.0092 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0675 | 0.1472 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0454 | 0.339 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0035 | 0.0358 | 0.2505 |
Schistosoma mansoni | tar DNA-binding protein | 0.0191 | 0.3638 | 0.7933 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0241 | 0.4675 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0028 | 0.0202 | 0.0556 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0407 | 0.1119 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0407 | 0.0696 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0026 | 0.0153 | 0.0602 |
Loa Loa (eye worm) | pyruvate kinase | 0.0069 | 0.1063 | 0.2922 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0142 | 0.0391 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0219 | 0.0219 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0026 | 0.0153 | 0.0602 |
Plasmodium falciparum | glutathione reductase | 0.0074 | 0.1167 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0092 | 0.0092 |
Echinococcus granulosus | geminin | 0.0177 | 0.3343 | 0.3343 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0407 | 0.3274 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0026 | 0.0153 | 0.0153 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0426 | 0.1171 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.005 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1112 | 0.3058 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0026 | 0.0153 | 0.0667 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0092 | 0.0201 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0454 | 0.3753 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0454 | 0.3753 |
Plasmodium falciparum | pyruvate kinase 2 | 0.0035 | 0.0358 | 0.2505 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0407 | 0.1119 |
Plasmodium vivax | pyruvate kinase 2, putative | 0.0035 | 0.0358 | 0.2505 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0219 | 0.0603 |
Echinococcus granulosus | pyruvate kinase | 0.0035 | 0.0358 | 0.0358 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0407 | 0.2958 |
Echinococcus granulosus | pyruvate kinase | 0.0035 | 0.0358 | 0.0358 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0023 | 0.0088 | 0.0088 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0023 | 0.0088 | 0.0241 |
Brugia malayi | MH2 domain containing protein | 0.0143 | 0.2617 | 0.7193 |
Trypanosoma brucei | trypanothione reductase | 0.0074 | 0.1167 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0026 | 0.0153 | 0.0667 |
Brugia malayi | Thioredoxin reductase | 0.0074 | 0.1167 | 0.3208 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0407 | 0.1119 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0028 | 0.0202 | 0.0556 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0026 | 0.0153 | 0.0602 |
Onchocerca volvulus | 0.0038 | 0.0407 | 0.383 | |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0048 | 0.0625 | 0.1717 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0454 | 0.339 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0407 | 0.1119 |
Brugia malayi | glutathione reductase | 0.0074 | 0.1167 | 0.3208 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.016 | 0.2966 | 0.8153 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0407 | 0.0129 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0069 | 0.1063 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0187 | 0.3551 | 0.7548 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0074 | 0.1167 | 0.3208 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0069 | 0.1063 | 0.9034 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0407 | 0.3274 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0407 | 0.3274 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0026 | 0.0153 | 0.0602 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0407 | 0.0407 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0169 | 0.3155 | 0.6687 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0454 | 0.0989 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0069 | 0.1063 | 0.2189 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0407 | 0.1119 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0407 | 0.3274 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0026 | 0.0153 | 0.0602 |
Plasmodium falciparum | thioredoxin reductase | 0.0026 | 0.0153 | 0.0602 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0026 | 0.0153 | 0.0602 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0407 | 0.3274 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0387 | 0.0844 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0075 | 0.1188 | 0.1188 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0407 | 0.3274 |
Echinococcus multilocularis | pyruvate kinase | 0.0035 | 0.0358 | 0.0358 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0407 | 0.0696 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0407 | 0.0888 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0048 | 0.0625 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0407 | 0.3274 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0219 | 0.0479 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0069 | 0.1063 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.005 | 0.0675 | 0.0675 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0169 | 0.3155 | 0.6687 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0219 | 0.122 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0026 | 0.0153 | 0.0602 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0347 | 0.0347 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0863 | 0.2373 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0074 | 0.1167 | 0.2353 |
Schistosoma mansoni | pyruvate kinase | 0.0069 | 0.1063 | 0.2318 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0069 | 0.1063 | 0.9034 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0407 | 0.1119 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0387 | 0.1064 |
Echinococcus granulosus | pyruvate kinase | 0.0069 | 0.1063 | 0.1063 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.004 | 0.0454 | 0.6815 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0494 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0026 | 0.0153 | 0.0602 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.1203 | 0.3307 |
Loa Loa (eye worm) | inositol-1 | 0.004 | 0.0454 | 0.1247 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0407 | 0.2958 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.2966 | 0.8153 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0407 | 0.0696 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0219 | 0.0479 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0675 | 0.1472 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0407 | 0.2958 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0026 | 0.0153 | 0.0602 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0651 | 0.1791 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0219 | 0.0219 |
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.0955 | 0.2082 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0407 | 0.1119 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0023 | 0.0088 | 0.0088 |
Echinococcus granulosus | pyruvate kinase | 0.0035 | 0.0358 | 0.0358 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0026 | 0.0153 | 0.1777 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0407 | 0.0129 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0879 | 0.0879 |
Echinococcus multilocularis | GPCR, family 2 | 0.005 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | glutathione reductase | 0.0074 | 0.1167 | 0.3208 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0219 | 0.122 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0026 | 0.0153 | 0.0667 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0456 | 0.0456 |
Mycobacterium tuberculosis | Probable reductase | 0.0169 | 0.3155 | 0.6687 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0094 | 0.1595 | 0.1595 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0675 | 0.1472 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0074 | 0.1167 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0074 | 0.1167 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0026 | 0.0153 | 0.1777 |
Giardia lamblia | Pyruvate kinase | 0.0035 | 0.0358 | 0.2772 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.3343 | 0.729 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0879 | 0.0879 |
Brugia malayi | TAR-binding protein | 0.0191 | 0.3638 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0387 | 0.1064 |
Schistosoma mansoni | pyruvate kinase | 0.0035 | 0.0358 | 0.0781 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0026 | 0.0153 | 0.0602 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0069 | 0.1063 | 0.2922 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0454 | 0.0989 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0036 | 0.0366 | 0.0606 |
Brugia malayi | Inositol-1 | 0.004 | 0.0454 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0518 | 0.1424 |
Plasmodium falciparum | thioredoxin reductase | 0.0074 | 0.1167 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0407 | 0.3274 |
Treponema pallidum | NADH oxidase | 0.0026 | 0.0153 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0074 | 0.1167 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0219 | 0.0603 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0407 | 0.1119 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0026 | 0.0153 | 0.0602 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.016 | 0.2966 | 0.8153 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0219 | 0.122 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0407 | 0.0696 |
Echinococcus multilocularis | geminin | 0.0177 | 0.3343 | 0.3343 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.