Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0023 | 0.0293 | 0.0293 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0293 | 0.0952 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0023 | 0.0293 | 0.0293 |
Schistosoma mansoni | acetylcholinesterase | 0.0023 | 0.0293 | 0.0832 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0137 | 0.2833 | 0.8042 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0784 | 0.2227 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0459 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0293 | 0.0832 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0293 | 0.0952 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0577 | 0.1876 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0577 | 0.1876 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0577 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0137 | 0.2833 | 0.2833 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0137 | 0.2833 | 0.9201 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.2833 | 0.9201 |
Onchocerca volvulus | 0.0023 | 0.0293 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0293 | 0.0832 |
Echinococcus granulosus | acetylcholinesterase | 0.0137 | 0.2833 | 0.2833 |
Onchocerca volvulus | 0.0023 | 0.0293 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0293 | 0.0952 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Onchocerca volvulus | 0.0023 | 0.0293 | 1 | |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0577 | 0.1639 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.3079 | 1 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0577 | 0.0577 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0023 | 0.0293 | 0.0832 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0784 | 0.2227 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0293 | 0.0952 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Echinococcus granulosus | muscleblind protein | 0.0148 | 0.3079 | 0.3079 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3523 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0148 | 0.3079 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3523 | 1 |
Echinococcus multilocularis | geminin | 0.0168 | 0.3523 | 0.3523 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0569 | 0.0569 |
Echinococcus multilocularis | neuroligin | 0.0023 | 0.0293 | 0.0293 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0577 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0137 | 0.2833 | 0.2833 |
Echinococcus granulosus | acetylcholinesterase | 0.0137 | 0.2833 | 0.2833 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0577 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0577 | 0.5 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0577 | 1 |
Schistosoma mansoni | gliotactin | 0.0023 | 0.0293 | 0.0832 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0023 | 0.0293 | 0.0293 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0784 | 0.2547 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.3079 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0784 | 0.0784 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0023 | 0.0293 | 0.0293 |
Echinococcus multilocularis | acetylcholinesterase | 0.0137 | 0.2833 | 0.2833 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0577 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0784 | 0.0784 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0032 | 0.0494 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0569 | 0.1616 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0577 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0023 | 0.0293 | 0.0293 |
Echinococcus granulosus | carboxylesterase 5A | 0.0137 | 0.2833 | 0.2833 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0784 | 0.2547 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0784 | 0.2227 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0032 | 0.0494 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0023 | 0.0293 | 0.0293 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Brugia malayi | Carboxylesterase family protein | 0.0137 | 0.2833 | 0.9201 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0023 | 0.0293 | 0.0832 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0569 | 0.1849 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0459 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0784 | 0.0784 |
Echinococcus multilocularis | muscleblind protein | 0.0148 | 0.3079 | 0.3079 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0784 | 0.0784 |
Onchocerca volvulus | 0.0023 | 0.0293 | 1 | |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0577 | 0.5 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0577 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0293 | 0.0952 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.2833 | 0.9201 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Onchocerca volvulus | 0.0023 | 0.0293 | 1 | |
Loa Loa (eye worm) | carboxylesterase | 0.0137 | 0.2833 | 0.9201 |
Brugia malayi | Carboxylesterase family protein | 0.0137 | 0.2833 | 0.9201 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0293 | 0.0952 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0148 | 0.3079 | 0.3079 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0569 | 0.1616 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0577 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0293 | 0.0832 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0577 | 0.5 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0577 | 0.1639 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0459 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Echinococcus granulosus | geminin | 0.0168 | 0.3523 | 0.3523 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0023 | 0.0293 | 0.0293 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0569 | 0.0569 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0577 | 0.0577 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.