Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | muscleblind protein | 0.0148 | 0.3079 | 0.3079 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0459 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0784 | 0.0784 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0577 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0293 | 0.0952 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0784 | 0.0784 |
Onchocerca volvulus | 0.0023 | 0.0293 | 1 | |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0577 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Onchocerca volvulus | 0.0023 | 0.0293 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.2833 | 0.9201 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0148 | 0.3079 | 0.3079 |
Loa Loa (eye worm) | carboxylesterase | 0.0137 | 0.2833 | 0.9201 |
Brugia malayi | Carboxylesterase family protein | 0.0137 | 0.2833 | 0.9201 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0293 | 0.0952 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0577 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0569 | 0.1616 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0459 | 1 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0577 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0293 | 0.0832 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0577 | 0.1639 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0023 | 0.0293 | 0.0293 |
Echinococcus granulosus | geminin | 0.0168 | 0.3523 | 0.3523 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0577 | 0.0577 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0569 | 0.0569 |
Echinococcus granulosus | acetylcholinesterase | 0.0137 | 0.2833 | 0.2833 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0577 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0023 | 0.0293 | 0.0293 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0577 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0023 | 0.0293 | 0.0832 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0577 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0784 | 0.0784 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0784 | 0.2547 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.3079 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0023 | 0.0293 | 0.0293 |
Echinococcus multilocularis | acetylcholinesterase | 0.0137 | 0.2833 | 0.2833 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0577 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0784 | 0.0784 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0032 | 0.0494 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0784 | 0.2227 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0032 | 0.0494 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0569 | 0.1616 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0023 | 0.0293 | 0.0293 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0577 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0137 | 0.2833 | 0.2833 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0784 | 0.2547 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0023 | 0.0293 | 0.0832 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0569 | 0.1849 |
Echinococcus granulosus | neuroligin | 0.0023 | 0.0293 | 0.0293 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Brugia malayi | Carboxylesterase family protein | 0.0137 | 0.2833 | 0.9201 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0293 | 0.0952 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0577 | 0.0577 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.3079 | 1 |
Onchocerca volvulus | 0.0023 | 0.0293 | 1 | |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0577 | 0.1639 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0023 | 0.0293 | 0.0832 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0784 | 0.2227 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0293 | 0.0952 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0293 | 0.0952 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3523 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0148 | 0.3079 | 1 |
Echinococcus multilocularis | geminin | 0.0168 | 0.3523 | 0.3523 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3523 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0148 | 0.3079 | 0.3079 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0569 | 0.0569 |
Echinococcus multilocularis | neuroligin | 0.0023 | 0.0293 | 0.0293 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0577 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0137 | 0.2833 | 0.2833 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0023 | 0.0293 | 0.0293 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0023 | 0.0293 | 0.0293 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0293 | 0.0952 |
Schistosoma mansoni | acetylcholinesterase | 0.0023 | 0.0293 | 0.0832 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0784 | 0.2227 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0137 | 0.2833 | 0.8042 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0293 | 0.0832 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0293 | 0.0952 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0459 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0577 | 0.5 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0577 | 0.1876 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0137 | 0.2833 | 0.2833 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0577 | 0.1876 |
Onchocerca volvulus | 0.0023 | 0.0293 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.2833 | 0.9201 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0137 | 0.2833 | 0.9201 |
Onchocerca volvulus | 0.0023 | 0.0293 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.0293 | 0.0832 |
Echinococcus granulosus | acetylcholinesterase | 0.0137 | 0.2833 | 0.2833 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.