Detailed information for compound 585472

Basic information

Technical information
  • TDR Targets ID: 585472
  • Name: [[(3R,10R,13R,17R)-17-[(1R)-1,5-dimethylhexyl ]-3-hydroxy-10,13-dimethyl-1,2,4,7,8,9,11,12, 14,15,16,17-dodecahydrocyclopenta[a]phenanthr en-3-yl]amino] 2-[(2,4,6-triiodophenyl)methyl ]butanoate
  • MW: 955.57 | Formula: C38H56I3NO3
  • H donors: 2 H acceptors: 2 LogP: 12.88 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCC(C(=O)ON[C@@]1(O)CC[C@]2(C(=CCC3C2CC[C@]2(C3CC[C@@H]2[C@@H](CCCC(C)C)C)C)C1)C)Cc1c(I)cc(cc1I)I
  • InChi: 1S/C38H56I3NO3/c1-7-25(19-29-33(40)20-27(39)21-34(29)41)35(43)45-42-38(44)18-17-36(5)26(22-38)11-12-28-31-14-13-30(24(4)10-8-9-23(2)3)37(31,6)16-15-32(28)36/h11,20-21,23-25,28,30-32,42,44H,7-10,12-19,22H2,1-6H3/t24-,25?,28?,30-,31?,32?,36+,37-,38-/m1/s1
  • InChiKey: OZOBNBRCHCPBJL-UHHODNAUSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[(2,4,6-triiodophenyl)methyl]butanoic acid [[(3R,10R,13R,17R)-17-[(1R)-1,5-dimethylhexyl]-3-hydroxy-10,13-dimethyl-1,2,4,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl]amino] ester
  • [[(3R,10R,13R,17R)-3-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,4,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl]amino] 2-[(2,4,6-triiodophenyl)methyl]butanoate
  • 2-(2,4,6-triiodobenzyl)butyric acid [[(3R,10R,13R,17R)-17-[(1R)-1,5-dimethylhexyl]-3-hydroxy-10,13-dimethyl-1,2,4,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl]amino] ester
  • cholesteryl iopanoate
  • 83172-18-3
  • Cholest-5-en-3-ol (3beta)-, 3-amino-alpha-ethyl-2,4,6-triiodobenzenepropanoate
  • Cholesterol iopanoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0076 0.0802 1
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0056 0.135
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.1809 0.5518
Echinococcus granulosus microtubule associated protein 2 0.0683 0.8646 1
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0254 0.5803
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0071 0.0218
Echinococcus multilocularis lamin 0.0027 0.016 0.0136
Brugia malayi beta-NAC-like protein 0.0034 0.0254 0.0776
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0132 0.2704
Onchocerca volvulus 0.0027 0.016 0.1973
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.016 0.0489
Echinococcus granulosus transcription factor btf3 0.0034 0.0254 0.0266
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0611 0.068
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0071 0.0054
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0056 0.135
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0056 0.017
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.1349 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0071 0.0054
Mycobacterium tuberculosis Probable reductase 0.0107 0.1195 0.8837
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0071 0.0218
Loa Loa (eye worm) hypothetical protein 0.0027 0.016 0.0489
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0071 0.0054
Schistosoma mansoni hypothetical protein 0.0076 0.0802 0.0902
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.016 0.0489
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0056 1
Echinococcus multilocularis transcription factor btf3 0.0034 0.0254 0.023
Schistosoma mansoni hypothetical protein 0.0055 0.0522 0.0576
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0446 0.1361
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0071 0.0218
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0446 0.0422
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0469
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0132 0.2704
Echinococcus granulosus lamin 0.0027 0.016 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0071 0.0218
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0254 0.5803
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0218
Schistosoma mansoni coup transcription factor 0.002 0.0071 0.0054
Brugia malayi hypothetical protein 0.0016 0.002 0.006
Schistosoma mansoni transcription factor btf3 0.0034 0.0254 0.0266
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.1178 0.3594
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0071 0.0218
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0254 0.5803
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0071 0.0218
Brugia malayi hypothetical protein 0.0113 0.128 0.3903
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.039 0.1188
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0071 0.0054
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0025 0.0076
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0056 0.0784
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0446 0.0422
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.042 1
Schistosoma mansoni hypothetical protein 0.0049 0.0446 0.0489
Echinococcus multilocularis musashi 0.0027 0.016 0.0136
Echinococcus multilocularis microtubule associated protein 2 0.0683 0.8646 0.8642
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0071 0.0218
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0071 0.0054
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0071 0.0218
Echinococcus multilocularis GPCR, family 2 0.0049 0.0446 0.0422
Brugia malayi ecdysteroid receptor 0.002 0.0071 0.0218
Entamoeba histolytica hypothetical protein 0.0034 0.0254 0.2658
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.039 0.0423
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0611 0.0587
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.1809 0.5518
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0218
Schistosoma mansoni nuclear hormone receptor 0.002 0.0071 0.0054
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0071 0.0047
Echinococcus granulosus FTZ F1 alpha 0.002 0.0071 0.0054
Brugia malayi hypothetical protein 0.0076 0.0802 0.2448
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0071 0.0054
Loa Loa (eye worm) intermediate filament protein 0.0027 0.016 0.0489
Echinococcus granulosus lamin dm0 0.0027 0.016 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0071 0.0218
Brugia malayi intermediate filament protein 0.0027 0.016 0.0489
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.1195 0.8837
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0522 0.1591
Toxoplasma gondii thioredoxin reductase 0.0047 0.042 1
Trypanosoma brucei trypanothione reductase 0.0047 0.042 1
Schistosoma mansoni intermediate filament proteins 0.0027 0.016 0.0157
Onchocerca volvulus 0.0055 0.0522 1
Schistosoma mansoni ap endonuclease 0.0019 0.0056 0.0036
Plasmodium falciparum thioredoxin reductase 0.0047 0.042 1
Leishmania major basic transcription factor 3a, putative 0.0034 0.0254 0.5803
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0056 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0218
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.1809 0.5518
Loa Loa (eye worm) hypothetical protein 0.0105 0.1178 0.3594
Echinococcus multilocularis survival motor neuron protein 1 0.0268 0.3279 0.3262
Entamoeba histolytica hypothetical protein 0.0076 0.0802 1
Schistosoma mansoni hypothetical protein 0.0165 0.1943 0.2226
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.1195 0.8837
Onchocerca volvulus 0.0027 0.016 0.1973
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0071 0.0218
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0071 0.0047
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.1195 0.8837
Schistosoma mansoni thyroid hormone receptor 0.002 0.0071 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0071 0.0218
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0071 0.0047
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0071 0.0054
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0071 0.0047
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.039 0.0423
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0254 0.5803
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.039 0.0423
Brugia malayi TAR-binding protein 0.0061 0.0611 0.1863
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0056 0.0234
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0218
Brugia malayi RNA binding protein 0.0061 0.0611 0.1863
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0446 0.1361
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.042 0.0396
Echinococcus granulosus survival motor neuron protein 1 0.0268 0.3279 0.3774
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0056 0.017
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0132 0.2704
Schistosoma mansoni thyroid hormone receptor 0.002 0.0071 0.0054
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0071 0.0054
Echinococcus granulosus geminin 0.0165 0.1943 0.2226
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0071 0.0218
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.1195 0.8837
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0246 0.3001 0.3452
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0071 0.0054
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0254 0.2658
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0071 0.0054
Schistosoma mansoni hypothetical protein 0.0049 0.0446 0.0489
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1315 0.401
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0071 0.0218
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0071 0.0047
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.1349 1
Toxoplasma gondii exonuclease III APE 0.0019 0.0056 0.0784
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0611 0.068
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0071 0.0047
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0071 0.0218
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0611 0.068
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0254 1
Brugia malayi Thioredoxin reductase 0.0047 0.042 0.1282
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0071 0.0218
Schistosoma mansoni hypothetical protein 0.0105 0.1178 0.1338
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0056 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.039 0.0423
Brugia malayi glutathione reductase 0.0047 0.042 0.1282
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0132 0.2704
Schistosoma mansoni lamin 0.0027 0.016 0.0157
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0802 0.078
Plasmodium vivax glutathione reductase, putative 0.0047 0.042 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0218
Schistosoma mansoni hypothetical protein 0.0049 0.0446 0.0489
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0071 0.0047
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0254 0.5803
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.042 0.0459
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0056 0.0784
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0254 0.0776
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0132 0.2704
Leishmania major hypothetical protein, conserved 0.0024 0.0132 0.2704
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0056 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0254 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0071 0.0054
Echinococcus multilocularis lamin dm0 0.0027 0.016 0.0136
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0132 0.2704
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0071 0.0054
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0071 0.0054
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0611 0.1863
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0071 0.0218
Schistosoma mansoni lamin 0.0027 0.016 0.0157
Brugia malayi nuclear hormone receptor 0.002 0.0071 0.0218
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0218
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.1195 0.8837
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.039 0.0423
Echinococcus granulosus leukotriene A 4 hydrolase 0.0246 0.3001 0.3452
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0025 0.5
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.042 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0056 0.0784
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0246 0.3001 0.9152
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0802 0.0902
Loa Loa (eye worm) hypothetical protein 0.0268 0.3279 1
Schistosoma mansoni ap endonuclease 0.0019 0.0056 0.0036
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0802 0.0902
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0446 0.0489
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.039 0.0366
Schistosoma mansoni hypothetical protein 0.0049 0.0446 0.0489
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0056 0.0784
Entamoeba histolytica hypothetical protein 0.0076 0.0802 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.039 0.0366
Loa Loa (eye worm) hypothetical protein 0.0049 0.0446 0.1361
Leishmania major trypanothione reductase 0.0047 0.042 1
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0446 0.1361
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0246 0.3001 0.2983
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0071 0.0054
Echinococcus granulosus GPCR family 2 0.0049 0.0446 0.0489
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0071 0.0218
Entamoeba histolytica hypothetical protein 0.0076 0.0802 1
Schistosoma mansoni survival motor neuron protein 0.0055 0.0522 0.0576
Brugia malayi nuclear receptor NHR-88 0.002 0.0071 0.0218
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0071 0.0218
Schistosoma mansoni hypothetical protein 0.0165 0.1943 0.2226
Brugia malayi hypothetical protein 0.0024 0.0132 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0254 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.1349 1
Echinococcus granulosus intermediate filament protein 0.0027 0.016 0.0157
Loa Loa (eye worm) glutathione reductase 0.0047 0.042 0.1282
Brugia malayi steroid hormone receptor 0.002 0.0071 0.0218
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0071 0.0218
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0254 0.5803
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0611 0.068
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0071 0.0218
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0611 0.1863
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0056 0.0036
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0056 0.0784
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1315 0.401
Brugia malayi MH2 domain containing protein 0.0116 0.1315 0.401
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0056 0.0784
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0071 0.0047
Plasmodium falciparum glutathione reductase 0.0047 0.042 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.042 0.2985
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0071 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0071 0.0218
Loa Loa (eye worm) hypothetical protein 0.0154 0.1809 0.5518
Loa Loa (eye worm) hypothetical protein 0.0024 0.0132 0.0402
Echinococcus multilocularis geminin 0.0165 0.1943 0.1923
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.039 0.1188
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0071 0.0054
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0071 0.0054
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0132 0.2704
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0071 0.0218
Echinococcus granulosus tar DNA binding protein 0.0061 0.0611 0.068
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0446 0.0489
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0071 0.0218
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0071 0.0047
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.042 0.1282
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0218
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0611 0.068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0071 0.0218
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0218
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0056 1
Schistosoma mansoni microtubule-associated protein tau 0.0683 0.8646 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0611 0.1863
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.1349 1
Brugia malayi hypothetical protein 0.0268 0.3279 1
Loa Loa (eye worm) RNA binding protein 0.0061 0.0611 0.1863

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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