Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0657 | 0.0657 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0657 | 0.0657 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0049 | 0.069 | 0.069 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Onchocerca volvulus | 0.0359 | 1 | 1 | |
Giardia lamblia | Aldose reductase | 0.0359 | 1 | 0.5 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0104 | 0.2347 | 0.2347 |
Echinococcus multilocularis | aldehyde reductase | 0.0255 | 0.688 | 0.688 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0049 | 0.069 | 0.069 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0104 | 0.2347 | 0.2347 |
Onchocerca volvulus | 0.0359 | 1 | 1 | |
Plasmodium falciparum | aldehyde reductase, putative | 0.0104 | 0.2347 | 0.5 |
Onchocerca volvulus | 0.0359 | 1 | 1 | |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0657 | 0.0657 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0359 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0359 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0049 | 0.069 | 0.069 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0359 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0359 | 1 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | aldo keto reductase | 0.0359 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0049 | 0.069 | 0.069 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.3896 | 0.3896 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0049 | 0.069 | 0.069 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | aldo keto reductase | 0.0359 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0359 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0359 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0049 | 0.069 | 0.069 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0104 | 0.2347 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0359 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0049 | 0.069 | 0.069 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.069 | 0.069 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0359 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0049 | 0.069 | 0.069 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0049 | 0.069 | 0.069 |
Schistosoma mansoni | coup transcription factor | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | aldo keto reductase | 0.0359 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0049 | 0.069 | 0.069 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0359 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0049 | 0.069 | 0.069 |
Loa Loa (eye worm) | oxidoreductase | 0.0359 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0049 | 0.069 | 0.069 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0657 | 0.0657 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Onchocerca volvulus | 0.0104 | 0.2347 | 0.178 | |
Brugia malayi | Muscleblind-like protein | 0.0156 | 0.3896 | 0.3896 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0049 | 0.069 | 0.069 |
Loa Loa (eye worm) | oxidoreductase | 0.0359 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0359 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0049 | 0.069 | 0.069 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0049 | 0.069 | 0.069 |
Echinococcus granulosus | muscleblind protein | 0.0156 | 0.3896 | 0.3896 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0049 | 0.069 | 0.069 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0657 | 0.0657 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0049 | 0.069 | 0.069 |
Echinococcus granulosus | hypothetical protein | 0.0359 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0359 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0049 | 0.069 | 0.069 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0255 | 0.688 | 0.5922 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Onchocerca volvulus | 0.0359 | 1 | 1 | |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0049 | 0.069 | 0.069 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Onchocerca volvulus | 0.0359 | 1 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0657 | 0.0657 |
Entamoeba histolytica | aldose reductase, putative | 0.0359 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0049 | 0.069 | 0.069 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0359 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0049 | 0.069 | 0.069 |
Schistosoma mansoni | potassium channel beta | 0.0104 | 0.2347 | 0.2347 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0657 | 0.0657 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.3896 | 0.3896 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.069 | 0.069 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0104 | 0.2347 | 0.2347 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0104 | 0.2347 | 0.2347 |
Brugia malayi | ecdysteroid receptor | 0.0049 | 0.069 | 0.069 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0049 | 0.069 | 0.069 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.069 | 0.069 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.069 | 0.069 |
Loa Loa (eye worm) | hypothetical protein | 0.0359 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0049 | 0.069 | 0.069 |
Loa Loa (eye worm) | oxidoreductase | 0.0359 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0359 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0359 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | muscleblind protein | 0.0156 | 0.3896 | 0.3896 |
Echinococcus granulosus | aldo keto reductase | 0.0359 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0049 | 0.069 | 0.069 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0359 | 1 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0156 | 0.3896 | 0.3896 |
Entamoeba histolytica | aldose reductase, putative | 0.0359 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0049 | 0.069 | 0.069 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0049 | 0.069 | 0.069 |
Schistosoma mansoni | aldo-keto reductase | 0.0359 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0049 | 0.069 | 0.069 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0049 | 0.069 | 0.069 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0359 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0657 | 0.0657 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0049 | 0.069 | 0.069 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0359 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0359 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0359 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0049 | 0.069 | 0.069 |
Leishmania major | aldo-keto reductase-like protein | 0.0359 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0359 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0359 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.0359 | 1 | 1 |
Echinococcus granulosus | aldehyde reductase | 0.0255 | 0.688 | 0.688 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0359 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0049 | 0.069 | 0.069 |
Plasmodium vivax | aldehyde reductase, putative | 0.0104 | 0.2347 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.069 | 0.069 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0049 | 0.069 | 0.069 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0049 | 0.069 | 0.069 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0359 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0049 | 0.069 | 0.069 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0359 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0049 | 0.069 | 0.069 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0359 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0359 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.069 | 0.069 |
Brugia malayi | NADH-dependent xylose reductase | 0.0104 | 0.2347 | 0.2347 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0359 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0049 | 0.069 | 0.069 |
Schistosoma mansoni | thyroid hormone receptor | 0.0049 | 0.069 | 0.069 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0049 | 0.069 | 0.069 |
Trypanosoma cruzi | aldo-keto reductase | 0.0359 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0359 | 1 | 1 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0104 | 0.2347 | 0.2347 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0359 | 1 | 1 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0104 | 0.2347 | 0.5 |
Trypanosoma brucei | prostaglandin f synthase | 0.0359 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0657 | 0.0657 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0049 | 0.069 | 0.069 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0359 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0359 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0049 | 0.069 | 0.069 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0359 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0049 | 0.069 | 0.069 |
Onchocerca volvulus | 0.0359 | 1 | 1 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0049 | 0.069 | 0.069 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0049 | 0.069 | 0.069 |
Leishmania major | prostaglandin f synthase, putative | 0.0359 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.069 | 0.069 |
Brugia malayi | nuclear receptor NHR-88 | 0.0049 | 0.069 | 0.069 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0359 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0049 | 0.069 | 0.069 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0049 | 0.069 | 0.069 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0359 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.069 | 0.069 |
Entamoeba histolytica | aldose reductase, putative | 0.0359 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.