Detailed information for compound 585543

Basic information

Technical information
  • TDR Targets ID: 585543
  • Name: (2R,3R,4S,5R,6R)-2-(aminomethyl)-6-methoxy-te trahydropyran-3,4,5-triol
  • MW: 193.198 | Formula: C7H15NO5
  • H donors: 4 H acceptors: 3 LogP: -2.31 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CO[C@@H]1O[C@H](CN)[C@@H]([C@@H]([C@H]1O)O)O
  • InChi: 1S/C7H15NO5/c1-12-7-6(11)5(10)4(9)3(2-8)13-7/h3-7,9-11H,2,8H2,1H3/t3-,4+,5+,6-,7-/m1/s1
  • InChiKey: BJYPUAVFYCRNFH-VOQCIKJUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R,3R,4S,5R,6R)-2-(aminomethyl)-6-methoxytetrahydropyran-3,4,5-triol
  • (2R,3R,4S,5R,6R)-2-(aminomethyl)-6-methoxy-oxane-3,4,5-triol
  • (2R,3R,4S,5R,6R)-2-(aminomethyl)-6-methoxyoxane-3,4,5-triol
  • methyl-6-deoxy-6-aminogalactopyranoside
  • 83377-36-0
  • beta-D-Galactopyranoside, methyl 6-amino-6-deoxy-
  • 6-Mdagp
  • Methyl 6-amino-6-deoxy-beta-D-Galactopyranoside
  • Methyl-6-deoxy-6-amino-beta-D-galactopyranoside

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0319 1 1
Brugia malayi NADH-dependent xylose reductase 0.0092 0.1647 0.1647
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0319 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Leishmania major prostaglandin f synthase, putative 0.0319 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0319 1 1
Schistosoma mansoni pol-related 0.0319 1 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0319 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Trypanosoma brucei prostaglandin f synthase 0.0319 1 1
Echinococcus multilocularis aldo keto reductase 0.0319 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Mycobacterium leprae Conserved hypothetical protein 0.0227 0.6594 0.5922
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0319 1 1
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0092 0.1647 0.1647
Mycobacterium tuberculosis Probable oxidoreductase 0.0319 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0319 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0319 1 1
Echinococcus multilocularis aldo keto reductase 0.0319 1 1
Echinococcus multilocularis aldehyde reductase 0.0227 0.6594 0.6594
Echinococcus granulosus hypothetical protein 0.0319 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Echinococcus granulosus aldo keto reductase 0.0319 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0319 1 1
Onchocerca volvulus 0.0319 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Loa Loa (eye worm) oxidoreductase 0.0319 1 1
Schistosoma mansoni aldo-keto reductase 0.0319 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0319 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0319 1 1
Trypanosoma cruzi aldo/keto reductase, putative 0.0319 1 1
Onchocerca volvulus 0.0319 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Echinococcus multilocularis voltage gated potassium channel subunit 0.0092 0.1647 0.1647
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0319 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Entamoeba histolytica aldose reductase, putative 0.0319 1 1
Onchocerca volvulus 0.0319 1 1
Mycobacterium ulcerans oxidoreductase 0.0319 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0319 1 1
Giardia lamblia Aldose reductase 0.0319 1 0.5
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Echinococcus granulosus aldo keto reductase 0.0319 1 1
Loa Loa (eye worm) oxidoreductase 0.0319 1 1
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0319 1 1
Giardia lamblia Aldose reductase 0.0319 1 0.5
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0319 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Entamoeba histolytica aldose reductase, putative 0.0319 1 1
Entamoeba histolytica aldose reductase, putative 0.0319 1 1
Toxoplasma gondii aldose reductase, putative 0.0319 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0319 1 1
Schistosoma mansoni aldo-keto reductase 0.0319 1 1
Loa Loa (eye worm) oxidoreductase 0.0319 1 1
Plasmodium falciparum aldehyde reductase, putative 0.0092 0.1647 0.5
Loa Loa (eye worm) oxidoreductase 0.0319 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Schistosoma mansoni potassium channel beta 0.0092 0.1647 0.1647
Onchocerca volvulus 0.0319 1 1
Leishmania major aldo-keto reductase-like protein 0.0319 1 1
Echinococcus granulosus aldo keto reductase 0.0319 1 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0319 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Echinococcus granulosus voltage gated potassium channel subunit 0.0092 0.1647 0.1647
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Onchocerca volvulus 0.0319 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Echinococcus multilocularis aldo keto reductase 0.0319 1 1
Echinococcus granulosus aldehyde reductase 0.0227 0.6594 0.6594
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0319 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0319 1 1
Trypanosoma brucei aldo-keto reductase, putative 0.0319 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Plasmodium vivax aldehyde reductase, putative 0.0092 0.1647 0.5
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Trypanosoma cruzi aldo-keto reductase 0.0319 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0319 1 1
Plasmodium falciparum aldo-keto reductase, putative 0.0092 0.1647 0.5
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0319 1 1
Loa Loa (eye worm) hypothetical protein 0.0319 1 1
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0092 0.1647 0.5
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0319 1 1
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0092 0.1647 0.1647
Echinococcus multilocularis aldo keto reductase 0.0319 1 1
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0092 0.1647 0.1647
Trichomonas vaginalis aldo-keto reductase, putative 0.0319 1 1
Onchocerca volvulus 0.0092 0.1647 0.1647
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0319 1 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0319 1 1
Loa Loa (eye worm) oxidoreductase 0.0319 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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