Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.5169 | 0.5169 |
Trypanosoma cruzi | AMP deaminase 2, putative | 0.0054 | 0 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0166 | 1 | 1 |
Echinococcus multilocularis | adenosine deaminase | 0.0166 | 1 | 1 |
Plasmodium falciparum | adenosine deaminase | 0.0166 | 1 | 1 |
Schistosoma mansoni | adenosine deaminase-related | 0.0166 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0166 | 1 | 0.5 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0166 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.0166 | 1 | 1 |
Echinococcus granulosus | adenosine deaminase | 0.0166 | 1 | 1 |
Mycobacterium ulcerans | adenosine deaminase | 0.0166 | 1 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.5169 | 0.5169 |
Trypanosoma brucei | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0166 | 1 | 1 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0166 | 1 | 1 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0166 | 1 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.0054 | 0 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.5169 | 0.5169 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.0054 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.5169 | 0.5169 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0166 | 1 | 1 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0166 | 1 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0166 | 1 | 1 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.0054 | 0 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0166 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0166 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.0166 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.