Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0062 | 0.263 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1257 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.263 | 0.263 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0062 | 0.263 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0062 | 0.263 | 0.263 |
Echinococcus multilocularis | aldo keto reductase | 0.0062 | 0.263 | 0.263 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 0.263 | 0.263 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0062 | 0.263 | 0.263 |
Trypanosoma brucei | prostaglandin f synthase | 0.0062 | 0.263 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0062 | 0.263 | 0.263 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 0.263 | 0.263 |
Echinococcus multilocularis | aldo keto reductase | 0.0062 | 0.263 | 0.263 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0062 | 0.263 | 0.263 |
Giardia lamblia | Aldose reductase | 0.0062 | 0.263 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0062 | 0.263 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0062 | 0.263 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0062 | 0.263 | 0.263 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Entamoeba histolytica | aldose reductase, putative | 0.0062 | 0.263 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0062 | 0.263 | 0.5 |
Onchocerca volvulus | 0.0062 | 0.263 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0062 | 0.263 | 1 |
Onchocerca volvulus | 0.0062 | 0.263 | 1 | |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0062 | 0.263 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Onchocerca volvulus | 0.0062 | 0.263 | 1 | |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.1257 | 0.1257 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0062 | 0.263 | 0.5 |
Onchocerca volvulus | 0.0062 | 0.263 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 0.263 | 0.263 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0149 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1257 | 0.1257 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0062 | 0.263 | 0.263 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 0.263 | 0.263 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0062 | 0.263 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 0.263 | 0.263 |
Echinococcus multilocularis | aldo keto reductase | 0.0062 | 0.263 | 0.263 |
Schistosoma mansoni | pol-related | 0.0062 | 0.263 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0062 | 0.263 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0062 | 0.263 | 0.263 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1257 | 0.1257 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1257 | 0.4781 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Leishmania major | prostaglandin f synthase, putative | 0.0062 | 0.263 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 0.263 | 0.263 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0062 | 0.263 | 0.263 |
Echinococcus multilocularis | aldo keto reductase | 0.0062 | 0.263 | 0.263 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.1257 | 0.1257 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0062 | 0.263 | 0.5 |
Echinococcus multilocularis | aldehyde reductase | 0.0044 | 0.1115 | 0.1115 |
Echinococcus multilocularis | muscleblind protein | 0.0149 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1257 | 0.4781 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 0.263 | 0.263 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 0.263 | 0.263 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0062 | 0.263 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0062 | 0.263 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0062 | 0.263 | 0.263 |
Echinococcus granulosus | muscleblind protein | 0.0149 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1257 | 0.4781 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0062 | 0.263 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1257 | 0.1257 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Echinococcus granulosus | aldo keto reductase | 0.0062 | 0.263 | 0.263 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0062 | 0.263 | 0.263 |
Mycobacterium ulcerans | oxidoreductase | 0.0062 | 0.263 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Echinococcus granulosus | aldehyde reductase | 0.0044 | 0.1115 | 0.1115 |
Trypanosoma cruzi | aldo-keto reductase | 0.0062 | 0.263 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0062 | 0.263 | 0.263 |
Schistosoma mansoni | aldo-keto reductase | 0.0062 | 0.263 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0062 | 0.263 | 0.263 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0062 | 0.263 | 0.5 |
Onchocerca volvulus | 0.0062 | 0.263 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0062 | 0.263 | 0.263 |
Loa Loa (eye worm) | oxidoreductase | 0.0062 | 0.263 | 0.263 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.