Detailed information for compound 58701

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 438.95 | Formula: C24H27ClN4O2
  • H donors: 1 H acceptors: 2 LogP: 4.09 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCNc1ccc2c3c1cc1c(Cl)cccc1c3c(=O)n(c2=O)CCN(C)C)C
  • InChi: 1S/C24H27ClN4O2/c1-27(2)11-10-26-20-9-8-16-21-18(20)14-17-15(6-5-7-19(17)25)22(21)24(31)29(23(16)30)13-12-28(3)4/h5-9,14,26H,10-13H2,1-4H3
  • InChiKey: IQCFWJIJLFBEFD-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus GPCR family 2 0.0031 0.0219 0.0187
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.038 0.416 0.5093
Loa Loa (eye worm) beta-lactamase 0.0036 0.0271 0.0293
Brugia malayi nuclear receptor RXR 0.0179 0.1893 0.2298
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0032 0.0226 0.0238
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0075 0.072 0.0848
Plasmodium vivax proteasome subunit beta type-4, putative 0.0112 0.1129 0.1737
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0332
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.072 0.089
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Echinococcus granulosus allatostatin A receptor 0.0075 0.072 0.069
Brugia malayi Nuclear hormone receptor family member nhr-1 0.038 0.416 0.5102
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0112 0.1129 0.1351
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0271 0.0239
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.072 0.069
Echinococcus multilocularis proteasome subunit beta type 7 0.0112 0.1129 0.11
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0146 0.0135
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0273 0.2957 0.3613
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0273 0.2951 0.3605
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0075 0.072 0.069
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.4451 0.4433
Schistosoma mansoni cytochrome P450 0.0025 0.0146 0.018
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0015 0.0034 0.0042
Brugia malayi Nuclear hormone receptor-like 1 0.038 0.416 0.5102
Brugia malayi Cytochrome P450 family protein 0.0062 0.0574 0.0667
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0679 0.0649
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0082 0.0102
Loa Loa (eye worm) hypothetical protein 0.0315 0.3423 0.419
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0179 0.1893 0.1866
Schistosoma mansoni hypothetical protein 0.0406 0.4451 0.5505
Brugia malayi proteasome subunit alpha type 6 0.0112 0.1129 0.1353
Loa Loa (eye worm) proteasome subunit beta type 3 0.0112 0.1129 0.1353
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.038 0.416 0.5145
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0897 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0179 0.1893 0.1866
Echinococcus multilocularis g protein coupled receptor 0.0075 0.072 0.069
Brugia malayi Nuclear hormone receptor E75 0.0179 0.1893 0.2298
Brugia malayi Cytochrome P450 family protein 0.0033 0.0244 0.0259
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.1189 0.1161
Brugia malayi bZIP transcription factor family protein 0.0083 0.0809 0.0958
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0112 0.1129 0.1396
Onchocerca volvulus 0.0036 0.0271 0.0233
Giardia lamblia 20S proteasome alpha subunit 4 0.0112 0.1129 0.1659
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0563 0.0696
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Giardia lamblia Proteasome subunit beta type 1 0.0441 0.4854 0.7684
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0363
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.0104 0.0095
Onchocerca volvulus 0.0041 0.0328 0.0303
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0015 0.0033 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0271 0.0363
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0112 0.1129 0.1737
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0279 0.0247
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0025 0.0146 0.0162
Brugia malayi Pre-SET motif family protein 0.0207 0.2207 0.2687
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0025 0.0146 0.0162
Schistosoma mansoni tyrosine kinase 0.0047 0.0404 0.0499
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0026 0.0158 0.0019
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0082 0.005
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) DR-78 0.0179 0.1893 0.2298
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Brugia malayi Tyrosine-protein kinase abl-1 0.0019 0.0077 0.0053
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.072 0.069
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0104 0.0125
Echinococcus granulosus peptide allatostatin:somatostatin 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0082 0.005
Brugia malayi proteasome subunit alpha type 3 0.0112 0.1129 0.1353
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1351
Onchocerca volvulus 0.0028 0.019 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Leishmania major cytochrome p450-like protein 0.0025 0.0146 0.0135
Echinococcus granulosus 7TM GPCR rhodopsin 0.0075 0.072 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0398 0.0447
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Giardia lamblia 20S proteasome alpha subunit 5 0.0112 0.1129 0.1659
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0025 0.0146 0.0162
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0259 0.0285
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0441 0.4854 0.4837
Echinococcus granulosus phospholipase D1 0.0102 0.102 0.0991
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0016 0.0052 0.0012
Giardia lamblia Farnesyl diphosphate synthase 0.0102 0.1017 0.1479
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0026 0.0158 0.0153
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Brugia malayi Serotonin receptor 0.0075 0.072 0.0848
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0568 0.6285 0.7772
Brugia malayi Nuclear hormone receptor-like 1 0.0201 0.2135 0.2598
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0112 0.1129 0.1737
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Brugia malayi Cytochrome P450 family protein 0.0033 0.0244 0.0259
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0082 0.006
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0363
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0112 0.1129 0.1687
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0089 0.0056
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi nuclear receptor NHR-88 0.038 0.416 0.5102
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.072 0.089
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Echinococcus multilocularis serotonin receptor 0.0196 0.2085 0.2059
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0025 0.0146 0.0162
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0112 0.1129 0.1396
Leishmania major hypothetical protein, conserved 0.0036 0.0271 0.029
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0082 0.005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0219 0.0229
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0041 0.0328 0.0296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Echinococcus granulosus microtubule associated protein 2 0.0685 0.7601 0.7593
Schistosoma mansoni adapter molecule crk 0.0015 0.0034 0.0042
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0045 0.001
Echinococcus granulosus RUN 0.002 0.0089 0.0056
Trypanosoma cruzi 20S proteasome subunit 0.0273 0.2957 0.3613
Echinococcus multilocularis 0.0092 0.0902 0.0873
Brugia malayi Polyprenyl synthetase family protein 0.0102 0.1017 0.1215
Loa Loa (eye worm) hypothetical protein 0.0731 0.8121 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0075 0.072 0.089
Echinococcus multilocularis thyroid hormone receptor alpha 0.0505 0.5571 0.5556
Echinococcus granulosus alpha 1A adrenergic receptor 0.0075 0.072 0.069
Leishmania major proteasome beta 7 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis peroxidasin 0.0026 0.0162 0.013
Schistosoma mansoni rab6-interacting 0.002 0.0089 0.011
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.038 0.416 0.5145
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Giardia lamblia 20S proteasome alpha subunit 7 0.0112 0.1129 0.1659
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0371 0.0414
Echinococcus granulosus fmrfamide receptor 0.0075 0.072 0.069
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0082 0.005
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0187 0.0186
Mycobacterium leprae Probable lipase LipE 0.0036 0.0271 0.0204
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0104 0.0095
Brugia malayi Dopamine receptor protein 2 0.0075 0.072 0.0848
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi Nuclear hormone receptor family member nhr-3 0.038 0.416 0.5102
Onchocerca volvulus 0.0179 0.1893 0.2259
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Toxoplasma gondii proteasome subunit alpha type, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0112 0.1129 0.1353
Toxoplasma gondii proteasome subunit alpha1, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0486 0.536 0.6586
Echinococcus granulosus phospholipase D 0.009 0.0886 0.0856
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0209 0.0259
Loa Loa (eye worm) TK protein kinase 0.004 0.0321 0.0355
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Brugia malayi Nuclear hormone receptor family member nhr-40 0.038 0.416 0.5102
Echinococcus multilocularis allatostatin A receptor 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Loa Loa (eye worm) TK protein kinase 0.0033 0.0237 0.0251
Echinococcus granulosus neuropeptide receptor 0.0075 0.072 0.069
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0089 0.007
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.019 0.0192
Plasmodium vivax amine transporter, putative 0.0041 0.0328 0.0453
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0441 0.4854 0.7692
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0244 0.0259
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0103 0.007
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0025 0.0146 0.0135
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0075 0.072 0.0848
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Onchocerca volvulus 0.0036 0.0271 0.0233
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Schistosoma mansoni gabp alpha 0.0072 0.0679 0.084
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Schistosoma mansoni sodium-dependent amino acid transporter 0.0041 0.0328 0.0405
Brugia malayi RNA, U transporter 1 0.008 0.0776 0.0917
Loa Loa (eye worm) hypothetical protein 0.0028 0.0187 0.0189
Leishmania major importin beta-1 subunit, putative 0.0023 0.0127 0.0111
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.1278 0.125
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.2445 0.3847
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Toxoplasma gondii proteasome subunit 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.024 0.2577 0.3145
Brugia malayi G protein-coupled receptor F59B2.13 0.0075 0.072 0.0848
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0025 0.0146 0.0162
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0219 0.0187
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0025 0.0146 0.0135
Brugia malayi Proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Giardia lamblia GTOR 0.0045 0.0371 0.0434
Trypanosoma brucei Emopamil binding protein, putative 0.0273 0.2951 0.3605
Brugia malayi Importin beta-1 subunit 0.0028 0.0187 0.0189
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0441 0.4854 0.7706
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Echinococcus granulosus lamin b receptor 0.0047 0.0398 0.0367
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0478 0.5265 0.5249
Onchocerca volvulus 0.0075 0.072 0.0794
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0242 0.0317
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0045 0.0012
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Brugia malayi G-protein coupled receptor 0.0075 0.072 0.0848
Echinococcus granulosus g protein coupled receptor 0.0075 0.072 0.069
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Plasmodium vivax importin-beta 2, putative 0.0028 0.0187 0.0228
Schistosoma mansoni hypothetical protein 0.0168 0.1767 0.2185
Brugia malayi Serotonin receptor 0.0532 0.5876 0.7224
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0271 0.0363
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0104 0.0072
Schistosoma mansoni lipoxygenase 0.0117 0.1189 0.1471
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0103 0.007
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0441 0.4854 0.5959
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0047 0.0404 0.0372
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0271 0.0239
Loa Loa (eye worm) hypothetical protein 0.0019 0.0085 0.0063
Loa Loa (eye worm) hypothetical protein 0.0067 0.0627 0.0733
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0244 0.0257
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0273 0.2957 0.4634
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Echinococcus granulosus importin subunit beta 1 0.0028 0.0187 0.0155
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.0809 0.0779
Schistosoma mansoni tyrosine kinase 0.0298 0.3234 0.3999
Leishmania major farnesyl pyrophosphate synthase 0.0102 0.1017 0.1213
Echinococcus multilocularis expressed protein 0.037 0.4051 0.4031
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0016 0.0052 0.0012
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi neuropeptide F receptor 0.0075 0.072 0.0848
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0441 0.4854 0.6001
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0101 0.0069
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Brugia malayi hypothetical protein 0.0179 0.1893 0.2298
Onchocerca volvulus 0.0075 0.072 0.0794
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0319 0.0395
Echinococcus multilocularis G protein coupled receptor 139 0.0075 0.072 0.069
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.072 0.069
Echinococcus multilocularis neuropeptide receptor A26 0.0532 0.5876 0.5862
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0441 0.4854 0.5959
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0104 0.0095
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.098
Leishmania major C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Brugia malayi steroid hormone receptor 0.038 0.416 0.5102
Loa Loa (eye worm) nuclear hormone receptor 0.0179 0.1893 0.2298
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) cytochrome P450 0.0025 0.0146 0.0138
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Echinococcus multilocularis G-protein coupled receptor, putative 0.0075 0.072 0.069
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0026 0.0158 0.0181
Echinococcus granulosus g protein coupled receptor 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0041 0.0328 0.0296
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis jun protein 0.0083 0.0809 0.0779
Schistosoma mansoni coup transcription factor 0.038 0.416 0.5145
Brugia malayi hypothetical protein 0.0036 0.0271 0.0293
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Entamoeba histolytica hypothetical protein 0.0035 0.0259 0.0285
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.038 0.416 0.5102
Onchocerca volvulus 0.0021 0.0104 0.0024
Echinococcus multilocularis cpg binding protein 0.003 0.0208 0.0176
Schistosoma mansoni adenoreceptor 0.0075 0.072 0.089
Brugia malayi Will die slowly protein 0.0727 0.8086 0.9957
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0127 0.0153
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni importin beta-1 0.0028 0.0187 0.0231
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0209 0.0259
Entamoeba histolytica phospholipase D, putative 0.0102 0.102 0.1512
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Echinococcus multilocularis phospholipase d3 0.0019 0.0085 0.0053
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0016 0.0052 0.0019
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0269 0.0287
Trichomonas vaginalis taga, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Brugia malayi Nuclear hormone receptor family member nhr-49 0.038 0.416 0.5102
Schistosoma mansoni nuclear receptor nhr-48 0.0179 0.1893 0.234
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Trypanosoma cruzi Emopamil binding protein, putative 0.0273 0.2951 0.3605
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0112 0.1129 0.1737
Brugia malayi Furin-like cysteine rich region family protein 0.0298 0.3234 0.3957
Onchocerca volvulus 0.0075 0.072 0.0794
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.072 0.089
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.072 0.069
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.2207 0.2687
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0179 0.1893 0.234
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0047 0.0404 0.0372
Trypanosoma brucei C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0082 0.006
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0112 0.1129 0.11
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.038 0.416 0.5102
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0082 0.005
Brugia malayi Doublecortin family protein 0.002 0.0089 0.0067
Brugia malayi hypothetical protein 0.0019 0.0082 0.006
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.072 0.069
Schistosoma mansoni tyrosine kinase 0.0019 0.0077 0.0095
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Brugia malayi Phospholipase D. Active site motif family protein 0.0036 0.027 0.0291
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0112 0.1129 0.1737
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0112 0.1129 0.1353
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0112 0.1129 0.1737
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0273 0.2957 0.3655
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0112 0.1129 0.1351
Schistosoma mansoni phospholipase D 0.0102 0.102 0.1262
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0045 0.0013
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0016 0.0052 0.0065
Echinococcus granulosus proteasome subunit beta type 6 0.0112 0.1129 0.11
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.072 0.089
Loa Loa (eye worm) nuclear receptor NHR-67 0.0179 0.1893 0.2298
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi Blistered cuticle protein 3 0.0026 0.0162 0.0158
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus neuropeptide receptor 0.0075 0.072 0.069
Brugia malayi 20S proteasome alpha5 subunit 0.0112 0.1129 0.1353
Brugia malayi Nuclear hormone receptor family member nhr-19 0.038 0.416 0.5102
Echinococcus granulosus tyrosine protein kinase Blk 0.004 0.0321 0.029
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Schistosoma mansoni glutathione synthetase 0.0026 0.0158 0.0195
Onchocerca volvulus 0.038 0.416 0.5093
Schistosoma mansoni steroid hormone receptor ad4bp 0.038 0.416 0.5145
Schistosoma mansoni opsin-like receptor 0.0075 0.072 0.089
Brugia malayi isocitrate dehydrogenase 0.0016 0.0045 0.0013
Brugia malayi Tachykinin-like peptides receptor 99D 0.0075 0.072 0.0848
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0271 0.0363
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0019 0.0077 0.0095
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.0104 0.1879
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Plasmodium vivax proteasome subunit beta type-1, putative 0.0441 0.4854 0.7706
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Echinococcus granulosus epidermal growth factor receptor 0.0161 0.1687 0.166
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0026 0.0158 0.0181
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0082 0.005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.038 0.416 0.5102
Schistosoma mansoni hypothetical protein 0.0168 0.1767 0.2185
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0112 0.1129 0.1687
Plasmodium falciparum transporter, putative 0.0041 0.0328 0.0453
Loa Loa (eye worm) PAS-3 protein 0.0112 0.1129 0.1353
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0259 0.0278
Loa Loa (eye worm) hypothetical protein 0.0021 0.0101 0.0083
Brugia malayi Steroid receptor seven-up type 2 0.038 0.416 0.5102
Echinococcus multilocularis tyrosine protein kinase Blk 0.004 0.0321 0.029
Loa Loa (eye worm) norepinephrine transporter 0.024 0.2577 0.3145
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0371 0.0466
Loa Loa (eye worm) hypothetical protein 0.003 0.0209 0.0216
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0025 0.0146 0.0162
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0045 0.001
Brugia malayi Proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Echinococcus granulosus neuropeptide s receptor 0.0532 0.5876 0.5862
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0219 0.0229
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0082 0.0102
Brugia malayi Cytochrome P450 family protein 0.0025 0.0146 0.0138
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0568 0.6285 0.773
Echinococcus multilocularis 0.0025 0.0146 0.0114
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0441 0.4854 0.5959
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0086 0.0836 0.1215
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.072 0.069
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0075 0.072 0.0848
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0127 0.0153
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0082 0.0102
Schistosoma mansoni tyrosine kinase 0.0157 0.1645 0.2034
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0201 0.2135 0.2598
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0082
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0254 0.0311
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0112 0.1129 0.1687
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0075 0.072 0.089
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi AKH receptor 0.0075 0.072 0.0848
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0112 0.1129 0.1396
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0328 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0166 0.0201
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0201 0.2135 0.2641
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0112 0.1129 0.1737
Schistosoma mansoni growth factor receptor-bound protein 0.0015 0.0034 0.0042
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0075 0.072 0.069
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0271 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Giardia lamblia 20S proteasome alpha subunit 6 0.0112 0.1129 0.1659
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0273 0.2957 0.2934
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0731 0.8121 1
Echinococcus multilocularis microtubule associated protein 2 0.0685 0.7601 0.7593
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0025 0.0146 0.0162
Echinococcus granulosus tyrosine protein kinase Lyn 0.0047 0.0404 0.0372
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0112 0.1129 0.11
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0398 0.0447
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi SRC-1 0.0047 0.0404 0.0457
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0075 0.072 0.069
Brugia malayi beta-lactamase family protein 0.0036 0.0271 0.0293
Leishmania major proteasome beta 2 subunit, putative 0.0112 0.1129 0.1351
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0371 0.0414
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni rab6-interacting 0.002 0.0089 0.011
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0082 0.006
Brugia malayi hypothetical protein 0.0026 0.0162 0.0158
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1869 0.2308
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0082 0.006
Echinococcus multilocularis fmrfamide receptor 0.0075 0.072 0.069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.038 0.416 0.5102
Brugia malayi PXA domain containing protein 0.0023 0.0133 0.0121
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0161 0.1687 0.166
Echinococcus multilocularis proteasome subunit beta type 6 0.0112 0.1129 0.11
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0298 0.0365
Echinococcus granulosus proteasome subunit beta t family 0.0112 0.1129 0.11
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0026 0.0158 0.0125
Echinococcus multilocularis phospholipase D 0.009 0.0886 0.0856
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0037 0.0004
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0082 0.005
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0237 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Giardia lamblia Proteasome subunit beta type 3 0.0112 0.1129 0.1659
Echinococcus multilocularis tyrosine protein kinase Srms 0.004 0.0321 0.029
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0112 0.1129 0.1396
Onchocerca volvulus 0.0065 0.0607 0.0652
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.1189 0.1161
Loa Loa (eye worm) hypothetical protein 0.0066 0.0618 0.0722
Loa Loa (eye worm) solute carrier family 6 member 4 0.024 0.2577 0.3145
Brugia malayi orphan nuclear receptor NR2E1 0.0179 0.1893 0.2298
Brugia malayi neuropeptide F receptor 0.0075 0.072 0.0848
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0273 0.2957 0.3657
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.1767 0.2102
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0112 0.1129 0.1687
Echinococcus granulosus nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0133 0.0121
Echinococcus multilocularis epidermal growth factor receptor 0.0161 0.1687 0.166
Echinococcus granulosus Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0102 0.1017 0.1558
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.038 0.416 0.5102
Leishmania major proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni biogenic amine receptor 0.0075 0.072 0.089
Echinococcus granulosus tyrosine protein kinase Src64B 0.0047 0.0404 0.0372
Entamoeba histolytica P-glycoprotein-1 0.0021 0.0104 0.0035
Echinococcus multilocularis growth factor receptor bound protein 2 0.0015 0.0034 0.0002
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0328 0.0405
Trypanosoma brucei proteasome alpha 7 subunit 0.0112 0.1129 0.1351
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0082 0.005
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.038 0.416 0.4141
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.038 0.416 0.4141
Brugia malayi nuclear hormone receptor family member odr-7 0.0179 0.1893 0.2298
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0219 0.0229
Brugia malayi larval opioid receptor 0.0075 0.072 0.0848
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0273 0.2951 0.3605
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0082 0.005
Onchocerca volvulus Neuropeptide F receptor homolog 0.0075 0.072 0.0794
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni nuclear hormone receptor 0.0179 0.1893 0.234
Schistosoma mansoni tyrosine kinase 0.0161 0.1687 0.2087
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0244 0.0257
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0112 0.1129 0.11
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0244 0.0259
Schistosoma mansoni myosin xvIII 0.0075 0.072 0.089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.0169
Brugia malayi Phospholipase d protein 1 0.0102 0.102 0.1219
Echinococcus multilocularis neuropeptide s receptor 0.0532 0.5876 0.5862
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus phospholipase d3 0.0019 0.0085 0.0053
Echinococcus multilocularis geminin 0.0168 0.1767 0.174
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0041 0.0328 0.0296
Echinococcus granulosus proteasome subunit alpha type 2 0.0112 0.1129 0.11
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi Proteasome A-type and B-type family protein 0.0568 0.6285 0.773
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.038 0.416 0.5145
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0271 0.0363
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0568 0.6285 0.773
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0075 0.072 0.069
Echinococcus granulosus jun protein 0.0083 0.0809 0.0779
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0102 0.1017 0.0988
Echinococcus granulosus tachykinin peptides receptor 99D 0.0075 0.072 0.069
Echinococcus multilocularis protein will die slowly 0.0727 0.8086 0.808
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0453
Trypanosoma cruzi polyprenyl synthase, putative 0.0026 0.0158 0.015
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0075 0.072 0.089
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis epidermal growth factor receptor 0.0298 0.3234 0.3212
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0273 0.2957 0.3613
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0082 0.006
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0082 0.005
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0037 0.0045
Brugia malayi sulfakinin receptor protein 0.0075 0.072 0.0848
Schistosoma mansoni cpg binding protein 0.003 0.0208 0.0257
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.038 0.416 0.4141
Schistosoma mansoni neuropeptide f receptor 76f 0.0075 0.072 0.089
Schistosoma mansoni multidrug resistance protein 0.0021 0.0104 0.0129
Trichomonas vaginalis abcb9, putative 0.0021 0.0104 0.0125
Brugia malayi Sodium:neurotransmitter symporter family protein 0.024 0.2577 0.3145
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0112 0.1129 0.1737
Echinococcus granulosus neuropeptide receptor A26 0.0532 0.5876 0.5862
Echinococcus granulosus ecdysone induced protein 78C 0.038 0.416 0.4141
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0089 0.007
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0271 0.0204
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0093
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0271 0.0335
Loa Loa (eye worm) fli-1 protein 0.0218 0.2331 0.2841
Leishmania major proteasome beta 5 subunit, putative 0.0568 0.6285 0.773
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni thyroid hormone receptor 0.0505 0.5571 0.6889
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0209 0.0264
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0041 0.0328 0.0296
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Brugia malayi putative neuropeptide receptor 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0271 0.0363
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Echinococcus multilocularis RUN 0.002 0.0089 0.0056
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.1278 0.125
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0209 0.0259
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0104 0.0072
Loa Loa (eye worm) TYRA-2 protein 0.0075 0.072 0.0848
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0041 0.0328 0.0296
Leishmania major sterol C-24 reductase, putative 0.0047 0.0398 0.0447
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0089 0.0056
Brugia malayi beta-lactamase 0.0036 0.0271 0.0293
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) hypothetical protein 0.0021 0.0104 0.0086
Echinococcus multilocularis serotonin transporter 0.024 0.2577 0.2553
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0082 0.006
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0179 0.1893 0.2298
Plasmodium falciparum importin beta, putative 0.0028 0.0187 0.0228
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0112 0.1129 0.1351
Giardia lamblia 20S proteasome alpha subunit 2 0.0112 0.1129 0.1659
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0271 0.0332
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0037 0.0003
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0112 0.1129 0.11
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0441 0.4854 0.7706
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0259 0.0318
Echinococcus multilocularis serotonin receptor 0.0196 0.2085 0.2059
Echinococcus granulosus somatostatin receptor 0.0075 0.072 0.069
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0112 0.1129 0.11
Brugia malayi Nuclear hormone receptor E75 0.0179 0.1893 0.2298
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0328 0.0405
Trichomonas vaginalis set domain proteins, putative 0.0236 0.2529 0.3125
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Echinococcus granulosus insulin receptor 0.0097 0.0959 0.093
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Onchocerca volvulus 0.003 0.0209 0.0155
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.038 0.416 0.5102
Schistosoma mansoni amine GPCR 0.0404 0.4432 0.5481
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.038 0.416 0.4141
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0332
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.072 0.069
Leishmania major proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0102 0.1017 0.1558
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0104 0.0072
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0209 0.0177
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0104 0.0072
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Trypanosoma brucei cardiolipin synthetase, putative 0.0036 0.027 0.0288
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.004 0.0321 0.029
Leishmania major proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0025 0.0146 0.0162
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0104 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0025 0.0146 0.0162
Onchocerca volvulus 0.0075 0.072 0.0794
Onchocerca volvulus 0.0179 0.1893 0.2259
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0112 0.1129 0.1687
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0162 0.0096
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0102 0.1017 0.1213
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0271 0.0239
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0179 0.1893 0.234
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1869 0.2308
Trypanosoma brucei C-8 sterol isomerase, putative 0.0731 0.8121 1
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0373 0.4086 0.501
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0047 0.0404 0.0372
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0112 0.1129 0.1737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.0169
Schistosoma mansoni ran 0.0021 0.0103 0.0127
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Echinococcus granulosus Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0731 0.8121 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Trichomonas vaginalis abcb9, putative 0.0021 0.0104 0.0125
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0112 0.1129 0.1396
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0102 0.1017 0.1419
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Echinococcus granulosus peroxidasin 0.0026 0.0162 0.013
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Schistosoma mansoni tyrosine kinase 0.0157 0.1645 0.2034
Entamoeba histolytica Ran family GTPase 0.0021 0.0103 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0441 0.4854 0.6002
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0075 0.072 0.0794
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0112 0.1129 0.1351
Echinococcus multilocularis somatostatin receptor 0.0075 0.072 0.069
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0271 0.0332
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0102 0.1017 0.1558
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Schistosoma mansoni nuclear hormone receptor 0.038 0.416 0.5145
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0187 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0089 0.0056
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0085
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi G protein-coupled receptor 0.0075 0.072 0.0848
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0082 0.006
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0328 0.0453
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0277 0.2997 0.2974
Giardia lamblia 20S proteasome alpha subunit 1 0.0112 0.1129 0.1659
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0067
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.072 0.069
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0025 0.0146 0.0162
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Leishmania major solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0568 0.6285 0.7773
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0179 0.1893 0.2259
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0371 0.0417
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0026 0.0158 0.0181
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0112 0.1129 0.1353
Brugia malayi nuclear hormone receptor 0.038 0.416 0.5102
Schistosoma mansoni loxhd1 0.002 0.0089 0.011
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0075 0.072 0.089
Schistosoma mansoni hypothetical protein 0.0727 0.8086 1
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0112 0.1129 0.11
Leishmania major basic transcription factor 3a, putative 0.0035 0.0259 0.0276
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0259 0.0276
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0127 0.0111
Schistosoma mansoni nuclear receptor 0.0179 0.1893 0.234
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0026 0.0158 0.0121
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0089 0.0056
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0026 0.0158 0.0181
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0271 0.0363
Loa Loa (eye worm) hypothetical protein 0.0486 0.536 0.6586
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0281 0.0249
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0075 0.072 0.069
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0259 0.0318
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0075 0.072 0.089
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.019 0.0158
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Mycobacterium ulcerans beta-lactamase 0.0036 0.0271 0.0204
Echinococcus granulosus snurportin 1 0.0302 0.3277 0.3255
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0082 0.006
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0273 0.2957 0.3657
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0273 0.2957 0.4667
Echinococcus multilocularis transcription factor btf3 0.0035 0.0259 0.0228
Onchocerca volvulus 0.0075 0.072 0.0794
Mycobacterium ulcerans proteasome PrcB 0.0568 0.6285 1
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0104 0.0035
Brugia malayi hypothetical protein 0.0179 0.1893 0.2298
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0026 0.0158 0.0125
Brugia malayi hypothetical protein 0.002 0.0089 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.038 0.416 0.5102
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0075 0.072 0.069
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0025 0.0146 0.0162
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0371 0.0459
Brugia malayi Ets-domain containing protein 0.0072 0.0679 0.0798
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0025 0.0146 0.0162
Entamoeba histolytica hypothetical protein 0.0023 0.0127 0.0071
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0259 0.0344
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0082
Onchocerca volvulus Peroxidase homolog 0.0026 0.0162 0.0096
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0112 0.1129 0.1601
Loa Loa (eye worm) proteasome subunit beta type 1 0.0441 0.4854 0.596
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0371 0.0414
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0179 0.1893 0.1866
Echinococcus granulosus FTZ F1 alpha 0.038 0.416 0.4141
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0162 0.0096
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0104 0.0086
Brugia malayi Pre-SET motif family protein 0.003 0.0209 0.0216
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0082 0.005
Echinococcus granulosus hypothetical protein 0.076 0.8453 0.8448
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0112 0.1129 0.1737
Schistosoma mansoni hypothetical protein 0.002 0.0089 0.011
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0082 0.005
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0146 0.0135
Echinococcus granulosus proteasome prosome macropain 0.0568 0.6285 0.6273
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus neuropeptide FF receptor 2 0.0075 0.072 0.069
Schistosoma mansoni sodium/chloride dependent transporter 0.024 0.2577 0.3187
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0047 0.0404 0.0372
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.0281 0.0305
Schistosoma mansoni tyrosine kinase 0.0047 0.0404 0.0499
Echinococcus granulosus Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0089 0.0056
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0102 0.1017 0.1558
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0271 0.0335
Loa Loa (eye worm) proteasome subunit beta type 2 0.0273 0.2957 0.3614
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0187 0.0228
Echinococcus granulosus growth factor receptor bound protein 2 0.0015 0.0034 0.0002
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1351
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0026 0.0158 0.0181
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.0125
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0112 0.1129 0.1687
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0162 0.0096
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Plasmodium falciparum proteasome subunit beta type-5 0.0568 0.6285 1
Loa Loa (eye worm) WD40 repeat protein 0.0727 0.8086 0.9957
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0112 0.1129 0.1396
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0254 0.0311
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0279 0.0247
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0082 0.0102
Echinococcus multilocularis sex peptide receptor 0.0075 0.072 0.069
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0075 0.072 0.069
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0162 0.0096
Schistosoma mansoni multidrug resistance protein 0.0021 0.0104 0.0129
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.072 0.0848
Giardia lamblia 20S proteasome alpha subunit 3 0.0112 0.1129 0.1659
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Loa Loa (eye worm) polyprenyl synthetase 0.0026 0.0158 0.0153
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Echinococcus multilocularis neuropeptide FF receptor 2 0.0075 0.072 0.069
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0082 0.006
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.0104 0.0035
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0077 0.005
Echinococcus multilocularis dro:myosuppressin receptor 0.0075 0.072 0.069
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Leishmania major proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi hypothetical protein 0.002 0.0089 0.0067
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) polyprenyl synthetase 0.0102 0.1017 0.1215
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0112 0.1129 0.1351
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0112 0.1129 0.1687
Schistosoma mansoni multidrug resistance protein 0.0021 0.0104 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-31 0.038 0.416 0.5102
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0082 0.0099
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0075 0.072 0.069
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0075 0.072 0.089
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0102 0.1017 0.1419
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0244 0.016
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Onchocerca volvulus 0.0041 0.0328 0.0303
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Leishmania major cytochrome p450-like protein 0.0033 0.0244 0.0257
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0112 0.1129 0.1737
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0045 0.001
Leishmania major C-8 sterol isomerase-like protein 0.0731 0.8121 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0112 0.1129 0.1737
Leishmania major cardiolipin synthetase, putative 0.0016 0.0052 0.0019
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0679 0.0798
Leishmania major proteasome beta 2 subunit, putative 0.0273 0.2957 0.3613
Echinococcus granulosus nuclear receptor nhr 48 0.0179 0.1893 0.1866
Brugia malayi hypothetical protein 0.0201 0.2135 0.2598
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0016 0.0052 0.0012
Brugia malayi cytochrome P450 0.0025 0.0146 0.0138
Echinococcus granulosus transcription factor btf3 0.0035 0.0259 0.0228
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0101 0.0069
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0219 0.0229
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Onchocerca volvulus 0.0727 0.8086 1
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0102 0.1017 0.1213
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Entamoeba histolytica P-glycoprotein-5 0.0021 0.0104 0.0035
Echinococcus multilocularis snurportin 1 0.0302 0.3277 0.3255
Schistosoma mansoni biogenic amine receptor 0.0075 0.072 0.089
Echinococcus granulosus G protein coupled receptor 139 0.0075 0.072 0.069
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0082 0.0102
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.0104 0.0083
Toxoplasma gondii peptidase, T1 family protein 0.0112 0.1129 0.1737
Echinococcus granulosus Proteasome subunit alpha beta 0.0112 0.1129 0.11
Echinococcus granulosus 7tm_1 domain containing protein 0.0075 0.072 0.069
Schistosoma mansoni histamine h1 receptor 0.0075 0.072 0.089
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.024 0.2577 0.3187
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0075 0.072 0.0848
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.038 0.416 0.5145
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0112 0.1129 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0209 0.0177
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Onchocerca volvulus 0.0026 0.0162 0.0096
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0026 0.0158 0.0121
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0025 0.0146 0.0162
Brugia malayi Proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0104 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0026 0.0158 0.0153
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0112 0.1129 0.1737
Echinococcus granulosus orexin receptor type 2 0.0075 0.072 0.069
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0026 0.0158 0.0125
Echinococcus granulosus NCK adaptor protein 0.0015 0.0034 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.038 0.416 0.5102
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0045 0.0013
Echinococcus multilocularis g protein coupled receptor 0.0075 0.072 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.072 0.069
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0102 0.1017 0.1255
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Schistosoma mansoni Lamin B receptor (ERG24) 0.0047 0.0398 0.0492
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0328 0.0296
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0089 0.0056
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0082 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0169 0.0205
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0075 0.072 0.069
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0025 0.0146 0.0162
Brugia malayi Nuclear hormone receptor family member nhr-25 0.038 0.416 0.5102
Trypanosoma cruzi Emopamil binding protein, putative 0.0273 0.2951 0.3605
Giardia lamblia Proteasome subunit beta type 2 0.0273 0.2957 0.4617
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0978 0.1168
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus multilocularis ecdysone induced protein 78C 0.038 0.416 0.4141
Brugia malayi proteasome subunit beta type 1 0.0441 0.4854 0.596
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0271 0.029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0209 0.0259
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0112 0.1129 0.1659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0026 0.0158 0.0125
Schistosoma mansoni RAR-like nuclear receptor 0.038 0.416 0.5145
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus multilocularis proteasome subunit alpha type 2 0.0112 0.1129 0.11
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Brugia malayi protein-tyrosine kinase 0.004 0.0321 0.0355
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0075 0.072 0.069
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0978 0.1168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0371 0.0456
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0025 0.0146 0.0162
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0047 0.0404 0.0372
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0075 0.072 0.089
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus multilocularis orexin receptor type 2 0.0075 0.072 0.069
Echinococcus multilocularis g protein coupled receptor 0.0075 0.072 0.069
Onchocerca volvulus 0.0036 0.0271 0.0233
Schistosoma mansoni tyrosine kinase 0.0157 0.1645 0.2034
Onchocerca volvulus Bile acid receptor homolog 0.038 0.416 0.5093
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0112 0.1129 0.1396
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0237 0.0205
Leishmania major hypothetical protein, conserved 0.0273 0.2951 0.3605
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0112 0.1129 0.1737
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.072 0.089
Schistosoma mansoni hypothetical protein 0.0036 0.0271 0.0335
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0219 0.0187
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0082 0.0102
Toxoplasma gondii hypothetical protein 0.0041 0.0328 0.0453
Brugia malayi photoreceptor-specific nuclear receptor 0.038 0.416 0.5102
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Schistosoma mansoni biogenic amine (5HT) receptor 0.0196 0.2085 0.2578
Onchocerca volvulus 0.0026 0.0162 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0082 0.0102
Brugia malayi Ets-domain containing protein 0.0072 0.0679 0.0798
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0127 0.0153
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0112 0.1129 0.1687
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0019 0.0077 0.0044
Toxoplasma gondii proteasome subunit beta type, putative 0.0568 0.6285 1
Brugia malayi beta-NAC-like protein 0.0035 0.0259 0.0278
Plasmodium vivax SET domain protein, putative 0.003 0.0209 0.0264
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Echinococcus granulosus proteasome subunit alpha type 6 0.0112 0.1129 0.11
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.038 0.416 0.4141
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0026 0.0158 0.0019
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0112 0.1129 0.1687
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0025 0.0146 0.0162
Leishmania major cytochrome p450-like protein 0.0025 0.0146 0.0135
Onchocerca volvulus 0.0026 0.0162 0.0096
Leishmania major GTP-binding protein, putative 0.0021 0.0103 0.0082
Echinococcus granulosus c src tyrosine kinase 0.0019 0.0077 0.0044
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0075 0.072 0.0848
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0082 0.005
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0019 0.0085 0.006
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.072 0.0848
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0259 0.0344
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0332
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0371 0.0414
Mycobacterium ulcerans lipase LipD 0.0036 0.0271 0.0204
Toxoplasma gondii hypothetical protein 0.0041 0.0328 0.0453
Loa Loa (eye worm) SRC-1 0.0047 0.0404 0.0457
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0169 0.0205
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus granulosus g-protein coupled receptor 0.0075 0.072 0.069
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0209 0.0177
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0045 0.0055
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0169 0.0205
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Schistosoma mansoni peroxidasin 0.0026 0.0162 0.0201
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Schistosoma mansoni nuclear receptor 0.0179 0.1893 0.234
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Schistosoma mansoni nuclear hormone receptor 0.0179 0.1893 0.234
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0102 0.1017 0.0988
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0102 0.1017 0.1255
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0271 0.029
Brugia malayi beta-lactamase family protein 0.0036 0.0271 0.0293
Loa Loa (eye worm) melatonin receptor type 1A 0.0075 0.072 0.0848
Brugia malayi Phospholipase D. Active site motif family protein 0.0019 0.0085 0.0063
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0075 0.072 0.0848
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0075 0.072 0.069
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0082 0.005
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0026 0.0158 0.0181
Echinococcus multilocularis lamin b receptor 0.0047 0.0398 0.0367
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0025 0.0146 0.0162
Schistosoma mansoni tyrosine kinase 0.0019 0.0077 0.0095
Echinococcus multilocularis neuropeptide receptor 0.0075 0.072 0.069
Plasmodium vivax proteasome subunit beta type-2, putative 0.0273 0.2957 0.4667
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0271 0.0335
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0112 0.1129 0.1396
Schistosoma mansoni microtubule-associated protein tau 0.0685 0.7601 0.94
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0102 0.1017 0.1258
Schistosoma mansoni ran 0.0021 0.0103 0.0127
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0328 0.0405
Onchocerca volvulus 0.0075 0.072 0.0794
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0568 0.6285 1
Plasmodium falciparum amino acid transporter, putative 0.0041 0.0328 0.0453
Brugia malayi CXXC zinc finger family protein 0.0028 0.019 0.0192
Trichomonas vaginalis esterase, putative 0.0036 0.0271 0.0332
Echinococcus granulosus proteasome subunit beta type 7 0.0112 0.1129 0.11
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0166 0.0201
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.072 0.069
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0045 0.0012
Brugia malayi hypothetical protein 0.0016 0.0052 0.0022
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Loa Loa (eye worm) hypothetical protein 0.0016 0.0052 0.0022
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1737
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0281 0.0249
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Onchocerca volvulus 0.0075 0.072 0.0794
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0271 0.0363
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Trypanosoma cruzi polyprenyl synthase, putative 0.0026 0.0158 0.015
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0075 0.072 0.069
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0568 0.6285 1
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0187 0.0155
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0067
Brugia malayi Dopamine receptor 0.0075 0.072 0.0848
Loa Loa (eye worm) TK/EGFR protein kinase 0.0298 0.3234 0.3957
Toxoplasma gondii heat shock protein hslv, putative 0.0112 0.1129 0.1737
Schistosoma mansoni hypothetical protein 0.0025 0.0146 0.018
Brugia malayi Nuclear hormone receptor family member nhr-25 0.038 0.416 0.5102
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.098
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0627 0.0733
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0271 0.029
Echinococcus granulosus dro:myosuppressin receptor 0.0075 0.072 0.069
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0271 0.0239
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0082 0.005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0589 0.652 0.6509
Echinococcus granulosus geminin 0.0168 0.1767 0.174
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Brugia malayi Nuclear hormone receptor family member nhr-41 0.038 0.416 0.5102
Echinococcus granulosus expressed protein 0.037 0.4051 0.4031
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0371 0.034
Leishmania major proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni hypothetical protein 0.0068 0.0632 0.0782
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0112 0.1129 0.1353
Echinococcus multilocularis FTZ F1 alpha 0.038 0.416 0.4141
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0363
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) doublecortin family protein 0.002 0.0089 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Plasmodium falciparum proteasome subunit beta type-4 0.0112 0.1129 0.1737
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0025 0.0146 0.0162
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0319 0.0395
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0102 0.1017 0.1213
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Toxoplasma gondii ABC1 family protein 0.0036 0.0271 0.0363
Trichomonas vaginalis WD repeat domain, putative 0.0727 0.8086 1
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0568 0.6285 1
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0082 0.0102
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0112 0.1129 0.1687
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0112 0.1129 0.11
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Loa Loa (eye worm) cytochrome P450 family protein 0.0062 0.0574 0.0667
Onchocerca volvulus Peroxidase homolog 0.0026 0.0162 0.0096
Brugia malayi hypothetical protein 0.0041 0.0328 0.0363
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus subfamily T1A non peptidase ue 0.0112 0.1129 0.11
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0075 0.072 0.089
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.3828
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.0104 0.0095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0371 0.0456
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Brugia malayi Nuclear hormone receptor-like 1 0.0201 0.2135 0.2598
Brugia malayi PXA domain containing protein 0.0023 0.0133 0.0121
Plasmodium vivax proteasome subunit beta type-6, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus granulosus protein will die slowly 0.0727 0.8086 0.808
Echinococcus granulosus dnaJ subfamily B 0.0406 0.4451 0.4433
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Schistosoma mansoni growth hormone secretagogue receptor 0.0075 0.072 0.089
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0328 0.0296
Echinococcus granulosus thyroid hormone receptor alpha 0.0179 0.1893 0.1866
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Schistosoma mansoni hypothetical protein 0.0067 0.0627 0.0775
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis insulin receptor 0.0097 0.0959 0.093
Brugia malayi conserved hypotetical protein 0.0179 0.1893 0.2298
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.2762 0.3373
Schistosoma mansoni Tr4/Tr2 (homologue) 0.038 0.416 0.5145
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Brugia malayi proteasome subunit beta type 3 0.0112 0.1129 0.1353
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Trypanosoma cruzi C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Onchocerca volvulus 0.0273 0.2951 0.3581
Trypanosoma brucei proteasome beta 6 subunit 0.0441 0.4854 0.5959
Schistosoma mansoni cpg binding protein 0.0028 0.019 0.0234
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0112 0.1129 0.1737
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.0195
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0047 0.0404 0.0372
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0371 0.034
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) hypothetical protein 0.0196 0.2085 0.2536
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Schistosoma mansoni hypothetical protein 0.0125 0.1278 0.1581
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0103 0.0093
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0025 0.0146 0.0162
Brugia malayi Peroxidasin 0.0026 0.0162 0.0158
Brugia malayi nuclear receptor NHR-67 0.0179 0.1893 0.2298
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.0281 0.0305
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0097 0.0959 0.093
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Echinococcus granulosus nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Onchocerca volvulus 0.0075 0.072 0.0794
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0371 0.0466
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0453
Schistosoma mansoni polycystin 1-related 0.002 0.0089 0.011
Loa Loa (eye worm) hypothetical protein 0.0098 0.0978 0.1168
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0271 0.0293
Plasmodium vivax proteasome subunit beta type-3, putative 0.0112 0.1129 0.1737
Brugia malayi hypothetical protein 0.0201 0.2135 0.2598
Echinococcus granulosus cytochrome P450 2K1 0.0025 0.0146 0.0114
Echinococcus granulosus tyrosine protein kinase Src42A 0.0047 0.0404 0.0372
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0201 0.2135 0.2641
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0112 0.1129 0.1396
Onchocerca volvulus 0.002 0.0089 0.0004
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0679 0.0649
Loa Loa (eye worm) hypothetical protein 0.0061 0.0562 0.0652
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0273 0.2957 0.4667
Onchocerca volvulus 0.0075 0.072 0.0794
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0271 0.0363
Trypanosoma brucei cardiolipin synthetase 0.0036 0.027 0.0288
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0219 0.0187
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0025 0.0146 0.0135
Loa Loa (eye worm) phospholipase D 0.0019 0.0085 0.0063
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0112 0.1129 0.1659
Schistosoma mansoni trans-prenyltransferase 0.0026 0.0158 0.0195
Brugia malayi proteasome subunit alpha type 4 0.0112 0.1129 0.1353
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0112 0.1129 0.11
Onchocerca volvulus 0.0041 0.0328 0.0303
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0037 0.0004
Entamoeba histolytica phospholipase D, putative 0.0102 0.102 0.1512
Schistosoma mansoni retinoid-x-receptor (RXR) 0.038 0.416 0.5145
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0259 0.0344
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.038 0.416 0.4141
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0104 0.0086
Onchocerca volvulus 0.002 0.0089 0.0004
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.049 0.0713
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.072 0.089
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0179 0.1893 0.1866
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0179 0.1893 0.2298
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0112 0.1129 0.1396
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0082 0.0102
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0371 0.0417
Onchocerca volvulus Protein ultraspiracle homolog 0.038 0.416 0.5093
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0045 0.001
Brugia malayi putative neuropeptide receptor NPR1 0.0075 0.072 0.0848
Schistosoma mansoni biogenic amine receptor 0.0075 0.072 0.089
Schistosoma mansoni opsin-like receptor 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0066 0.0618 0.0722
Schistosoma mansoni thyroid hormone receptor 0.0505 0.5571 0.6889
Brugia malayi G-protein coupled receptor 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0086 0.0836 0.0991
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0082 0.005
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis NCK adaptor protein 0.0015 0.0034 0.0002
Leishmania major polyprenyl synthase, putative 0.0026 0.0158 0.015
Loa Loa (eye worm) hypothetical protein 0.0081 0.0783 0.0926
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0269 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Trichomonas vaginalis abcb9, putative 0.0021 0.0104 0.0125
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0321 0.029
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Trypanosoma cruzi cardiolipin synthetase, putative 0.0036 0.027 0.0288
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0371 0.0414
Loa Loa (eye worm) hypothetical protein 0.0086 0.0836 0.0991
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Schistosoma mansoni ets-related 0.0218 0.2331 0.2883
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0082 0.006
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis conserved hypothetical protein 0.0685 0.7601 0.7593
Schistosoma mansoni growth factor receptor-bound protein 0.0015 0.0034 0.0042
Echinococcus multilocularis g-protein coupled receptor 0.0075 0.072 0.069
Schistosoma mansoni zinc finger protein 0.0179 0.1893 0.234
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Trypanosoma brucei proteasome beta 7 subunit 0.0112 0.1129 0.1351
Echinococcus granulosus serotonin receptor 0.0075 0.072 0.069
Echinococcus multilocularis tyrosine protein kinase Abl 0.0019 0.0077 0.0044
Trypanosoma cruzi cardiolipin synthetase, putative 0.0036 0.027 0.0288
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Echinococcus multilocularis c src tyrosine kinase 0.0019 0.0077 0.0044
Loa Loa (eye worm) hypothetical protein 0.0457 0.503 0.6178
Brugia malayi Polyprenyl synthetase family protein 0.0026 0.0158 0.0153
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Mycobacterium ulcerans hypothetical protein 0.0036 0.0271 0.0204
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.0104 0.0035
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0026 0.0158 0.0019
Brugia malayi tailless protein 0.0179 0.1893 0.2298
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0568 0.6285 0.773
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0259 0.0276
Schistosoma mansoni transcription factor btf3 0.0035 0.0259 0.0321
Brugia malayi hypothetical protein 0.0019 0.0082 0.006
Echinococcus multilocularis nuclear receptor nhr 48 0.0179 0.1893 0.1866
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0568 0.6285 0.773
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0179 0.1893 0.2259
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0047 0.0404 0.0372
Schistosoma mansoni tyrosine kinase 0.0161 0.1687 0.2087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.0169
Schistosoma mansoni tyrosine kinase 0.0097 0.0959 0.1187
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Echinococcus granulosus biogenic amine 5HT receptor 0.0196 0.2085 0.2059
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.038 0.416 0.5102
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0269 0.0287
Schistosoma mansoni lipoxygenase 0.0082 0.0792 0.0979
Brugia malayi follicle stimulating hormone receptor 0.0075 0.072 0.0848
Brugia malayi nuclear receptor NHR-88 0.0179 0.1893 0.2298
Schistosoma mansoni opsin-like receptor 0.0075 0.072 0.089
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0112 0.1129 0.1351
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.072 0.0848
Brugia malayi Proteasome subunit alpha type 7-1 0.0112 0.1129 0.1353
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0195 0.0237
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0041 0.0328 1
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0041 0.0328 0.0363
Schistosoma mansoni peroxidasin 0.0026 0.0162 0.0201
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0082 0.005
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0037 0.0003
Leishmania major proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0112 0.1129 0.1353
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.038 0.416 0.4141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.038 0.416 0.5102
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0102 0.1017 0.1255
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0568 0.6285 1
Trichomonas vaginalis ran, putative 0.0021 0.0103 0.0124
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Mycobacterium ulcerans proteasome PrcA 0.0112 0.1129 0.1601
Loa Loa (eye worm) hypothetical protein 0.024 0.2577 0.3145
Echinococcus multilocularis phospholipase D1 0.0102 0.102 0.0991
Brugia malayi RE15519p 0.0075 0.072 0.0848
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0075 0.072 0.0848
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0259 0.0318
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0097 0.0959 0.093
Brugia malayi hypothetical protein 0.0065 0.0607 0.0708
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0162 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0205 0.0251
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0075 0.072 0.0848
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-14 0.038 0.416 0.5102
Leishmania major proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0112 0.1129 0.1737
Schistosoma mansoni tyrosine kinase 0.0097 0.0959 0.1187
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0104 0.0035
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0259 0.0276
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.2762 0.3373
Schistosoma mansoni retinoic acid receptor RXR 0.0478 0.5265 0.6511
Loa Loa (eye worm) hypothetical protein 0.0196 0.2085 0.2536
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0112 0.1129 0.1687
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0371 0.0414
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0112 0.1129 0.1737
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0112 0.1129 0.1687
Brugia malayi Melatonin receptor type 1A 0.0075 0.072 0.0848
Brugia malayi Protein kinase domain containing protein 0.0097 0.0959 0.1144
Trypanosoma cruzi C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Onchocerca volvulus 0.0075 0.072 0.0794
Brugia malayi ORL1-like opioid receptor 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi Protein K4 0.0016 0.0052 0.0022
Echinococcus granulosus epidermal growth factor receptor 0.0298 0.3234 0.3212
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0112 0.1129 0.1737
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.0104 0.0035
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Onchocerca volvulus 0.0075 0.072 0.0794
Brugia malayi Proteasome subunit alpha type 1 0.0112 0.1129 0.1353
Echinococcus multilocularis proteasome (prosome, macropain) 0.0568 0.6285 0.6273
Onchocerca volvulus Notchless protein homolog 0.0112 0.1129 0.1304
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0112 0.1129 0.1659
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0025 0.0146 0.0162
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0201 0.2135 0.211
Echinococcus granulosus cpg binding protein 0.003 0.0208 0.0176
Brugia malayi proteasome subunit beta type 2 0.0273 0.2957 0.3614
Brugia malayi hypothetical protein 0.0121 0.1232 0.1481
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0112 0.1129 0.1687
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0047 0.0404 0.0372
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0273 0.2957 0.3655
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0112 0.1129 0.1737
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0273 0.2951 0.3605
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Toxoplasma gondii proteasome beta subunit 0.0112 0.1129 0.1737
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0103 0.0093
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0036 0.027 0.036
Schistosoma mansoni alpha-1 adrenergic receptor 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0271 0.0204
Brugia malayi ABC transporter family protein 0.0021 0.0104 0.0086
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0112 0.1129 0.1353
Brugia malayi ecdysone receptor 0.0179 0.1893 0.2298
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0244 0.0257
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0045 0.001
Toxoplasma gondii cytochrome p450 superfamily protein 0.0025 0.0146 0.0162
Echinococcus granulosus tyrosine kinase 0.004 0.0321 0.029
Echinococcus granulosus serotonin transporter 0.024 0.2577 0.2553
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0112 0.1129 0.11
Schistosoma mansoni nck2/grb4 0.0015 0.0034 0.0042
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0978 0.1168
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.038 0.416 0.4141
Entamoeba histolytica protein kinase, putative 0.0033 0.0237 0.0249
Echinococcus multilocularis fmrfamide receptor 0.0075 0.072 0.069
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0019 0.0077 0.0044
Brugia malayi Fli-1 protein 0.0218 0.2331 0.2841
Echinococcus multilocularis neuropeptide receptor 0.0075 0.072 0.069
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Brugia malayi proteasome subunit alpha type 1 0.0112 0.1129 0.1353
Brugia malayi nuclear receptor RXR 0.0201 0.2135 0.2598
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0453
Schistosoma mansoni cpg binding protein 0.003 0.0208 0.0257
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.3277 0.401
Loa Loa (eye worm) serotonin transporter b 0.024 0.2577 0.3145
Schistosoma mansoni hypothetical protein 0.0302 0.3277 0.4052
Echinococcus granulosus g protein coupled receptor 0.0075 0.072 0.069
Onchocerca volvulus 0.0236 0.2529 0.3055
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Treponema pallidum sodium- and chloride- dependent transporter 0.024 0.2577 1
Brugia malayi nuclear hormone receptor 0.0179 0.1893 0.2298
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.0809 0.0779
Onchocerca volvulus 0.024 0.2577 0.3115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0104 0.0086
Echinococcus multilocularis proteasome subunit alpha type 6 0.0112 0.1129 0.11
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0082 0.005
Loa Loa (eye worm) hypothetical protein 0.024 0.2577 0.3145
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.0125
Brugia malayi nuclear hormone receptor family member nhr-6 0.0179 0.1893 0.2298
Schistosoma mansoni smdr2 0.0021 0.0104 0.0129
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0244 0.0259
Brugia malayi ecdysteroid receptor 0.038 0.416 0.5102
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0085
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0112 0.1129 0.1737
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0219 0.0187
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0106 0.0086
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi GnHR receptor homolog 0.0075 0.072 0.0848
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0273 0.2957 0.2934
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0112 0.1129 0.1687
Brugia malayi proteasome subunit alpha type 2 0.0112 0.1129 0.1353
Leishmania major p-glycoprotein 0.0021 0.0104 0.0083
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Echinococcus granulosus tm gpcr rhodopsin 0.0589 0.652 0.6509
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Plasmodium vivax cardiolipin synthetase, putative 0.0016 0.0052 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Brugia malayi multidrug resistance protein 3 0.0021 0.0104 0.0086
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0271 0.0204
Leishmania major proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Plasmodium vivax proteasome subunit beta type-5, putative 0.0568 0.6285 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0075 0.072 0.0848
Schistosoma mansoni jun-related protein 0.0068 0.0632 0.0782
Echinococcus granulosus sex peptide receptor 0.0075 0.072 0.069
Loa Loa (eye worm) TK/INSR protein kinase 0.0097 0.0959 0.1144
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0026 0.0158 0.0121
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0371 0.0456
Brugia malayi Dopamine receptor protein 1 0.0075 0.072 0.0848
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0026 0.0158 0.015
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0112 0.1129 0.1687
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0112 0.1129 0.1687
Echinococcus multilocularis GPCR, family 2 0.0031 0.0219 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Loa Loa (eye worm) steroid hormone receptor 0.038 0.416 0.5102
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0441 0.4854 0.4837
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Plasmodium vivax proteasome subunit beta type-7, putative 0.0112 0.1129 0.1737
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0201 0.2135 0.211

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) = 3226 Cardiotoxicity by a neonatal rat heart myocyte assay ChEMBL. 8648600
IC50 (functional) = 2.9 nM Inhibitory activity against sensitive L1210 cell lines ChEMBL. 8648600
IC50 (functional) = 2.9 nM Inhibitory activity against sensitive L1210 cell lines ChEMBL. 8648600
IC50 (functional) = 6.8 nM Inhibitory activity against resistant murine leukemia L1210 cell lines. ChEMBL. 8648600
IC50 (functional) = 6.8 nM Inhibitory activity against resistant murine leukemia L1210 cell lines. ChEMBL. 8648600
IC50 (functional) = 29 nM Inhibitory activity against AUC375 cell line ChEMBL. 8648600
IC50 (functional) = 69 nM An average for IC50 values in the two solid tumor cell lines and sensitive L1210 leukemia cell line. ChEMBL. 8648600
IC50 (functional) = 103 nM An average for IC50 values in the two solid tumor cell lines. ChEMBL. 8648600
IC50 (functional) = 176 nM Inhibitory activity against OVCAR-3 cell line ChEMBL. 8648600
IC50 (functional) = 176 nM Inhibitory activity against OVCAR-3 cell line ChEMBL. 8648600
Toxicity ratio (functional) = 47 Toxicity ratio determined by the quotient of IC50 values in the mycocytes divided by the average value in the three tumor lines. ChEMBL. 8648600

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 8648600
Homo sapiens ChEMBL23 8648600

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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