Detailed information for compound 58701

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 438.95 | Formula: C24H27ClN4O2
  • H donors: 1 H acceptors: 2 LogP: 4.09 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCNc1ccc2c3c1cc1c(Cl)cccc1c3c(=O)n(c2=O)CCN(C)C)C
  • InChi: 1S/C24H27ClN4O2/c1-27(2)11-10-26-20-9-8-16-21-18(20)14-17-15(6-5-7-19(17)25)22(21)24(31)29(23(16)30)13-12-28(3)4/h5-9,14,26H,10-13H2,1-4H3
  • InChiKey: IQCFWJIJLFBEFD-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1869 0.2308
Onchocerca volvulus 0.0075 0.072 0.0794
Schistosoma mansoni multidrug resistance protein 0.0021 0.0104 0.0129
Echinococcus multilocularis phospholipase d3 0.0019 0.0085 0.0053
Toxoplasma gondii proteasome subunit alpha1, putative 0.0112 0.1129 0.1737
Echinococcus granulosus phospholipase d3 0.0019 0.0085 0.0053
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Schistosoma mansoni biogenic amine receptor 0.0075 0.072 0.089
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.072 0.069
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0589 0.652 0.6509
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0195 0.0237
Loa Loa (eye worm) TYRA-2 protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis FTZ F1 alpha 0.038 0.416 0.4141
Loa Loa (eye worm) hypothetical protein 0.0081 0.0783 0.0926
Echinococcus granulosus tm gpcr rhodopsin 0.0589 0.652 0.6509
Echinococcus multilocularis GPCR, family 2 0.0031 0.0219 0.0187
Echinococcus multilocularis orexin receptor type 2 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Loa Loa (eye worm) PAS-3 protein 0.0112 0.1129 0.1353
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0112 0.1129 0.1687
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0026 0.0158 0.0181
Plasmodium vivax cardiolipin synthetase, putative 0.0016 0.0052 0.0012
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0112 0.1129 0.1687
Echinococcus multilocularis proteasome subunit beta type 6 0.0112 0.1129 0.11
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.1189 0.1161
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0363
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0441 0.4854 0.6001
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0102 0.1017 0.1558
Schistosoma mansoni tyrosine kinase 0.0157 0.1645 0.2034
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0082 0.006
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0082 0.005
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.049 0.0713
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0112 0.1129 0.1687
Leishmania major proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Mycobacterium ulcerans lipase LipD 0.0036 0.0271 0.0204
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0568 0.6285 0.7773
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Schistosoma mansoni cytochrome P450 0.0025 0.0146 0.018
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Brugia malayi RE15519p 0.0075 0.072 0.0848
Echinococcus granulosus 7TM GPCR rhodopsin 0.0075 0.072 0.069
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0025 0.0146 0.0162
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0179 0.1893 0.1866
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0568 0.6285 0.7772
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.038 0.416 0.4141
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0025 0.0146 0.0162
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.038 0.416 0.5102
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0179 0.1893 0.2298
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.2762 0.3373
Echinococcus granulosus dnaJ subfamily B 0.0406 0.4451 0.4433
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.0104 0.0095
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.038 0.416 0.4141
Giardia lamblia Proteasome subunit beta type 3 0.0112 0.1129 0.1659
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0112 0.1129 0.1687
Echinococcus multilocularis c src tyrosine kinase 0.0019 0.0077 0.0044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0085 0.0063
Trypanosoma cruzi polyprenyl synthase, putative 0.0026 0.0158 0.015
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Loa Loa (eye worm) hypothetical protein 0.0196 0.2085 0.2536
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0075 0.072 0.069
Brugia malayi beta-lactamase family protein 0.0036 0.0271 0.0293
Loa Loa (eye worm) hypothetical protein 0.0031 0.0219 0.0229
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1737
Brugia malayi GnHR receptor homolog 0.0075 0.072 0.0848
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0254 0.0311
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0112 0.1129 0.1737
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0016 0.0052 0.0019
Loa Loa (eye worm) solute carrier family 6 member 4 0.024 0.2577 0.3145
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Echinococcus multilocularis serotonin receptor 0.0196 0.2085 0.2059
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0112 0.1129 0.1396
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Toxoplasma gondii heat shock protein hslv, putative 0.0112 0.1129 0.1737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0169 0.0205
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0082
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0037 0.0003
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0112 0.1129 0.1687
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0082 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Loa Loa (eye worm) TK protein kinase 0.004 0.0321 0.0355
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Echinococcus granulosus proteasome subunit beta type 6 0.0112 0.1129 0.11
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0089 0.007
Echinococcus granulosus cytochrome P450 2K1 0.0025 0.0146 0.0114
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0075 0.072 0.0848
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0273 0.2957 0.3655
Brugia malayi proteasome subunit beta type 2 0.0273 0.2957 0.3614
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Echinococcus granulosus Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Leishmania major sterol C-24 reductase, putative 0.0047 0.0398 0.0447
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0082 0.005
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0085
Schistosoma mansoni opsin-like receptor 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni sodium-dependent amino acid transporter 0.0041 0.0328 0.0405
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis neuropeptide receptor 0.0075 0.072 0.069
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0179 0.1893 0.1866
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0112 0.1129 0.1353
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0112 0.1129 0.1351
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.038 0.416 0.4141
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0025 0.0146 0.0135
Mycobacterium ulcerans proteasome PrcB 0.0568 0.6285 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1351
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0082 0.006
Schistosoma mansoni alpha-1 adrenergic receptor 0.0075 0.072 0.089
Schistosoma mansoni loxhd1 0.002 0.0089 0.011
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0102 0.1017 0.1213
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Leishmania major cardiolipin synthetase, putative 0.0016 0.0052 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0259 0.0318
Entamoeba histolytica P-glycoprotein-5 0.0021 0.0104 0.0035
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Schistosoma mansoni peroxidasin 0.0026 0.0162 0.0201
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1869 0.2308
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Giardia lamblia 20S proteasome alpha subunit 2 0.0112 0.1129 0.1659
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.0281 0.0305
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0112 0.1129 0.1737
Echinococcus granulosus proteasome prosome macropain 0.0568 0.6285 0.6273
Brugia malayi sulfakinin receptor protein 0.0075 0.072 0.0848
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0371 0.0417
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0441 0.4854 0.7706
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi hypothetical protein 0.0019 0.0082 0.006
Leishmania major proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Schistosoma mansoni tyrosine kinase 0.0019 0.0077 0.0095
Entamoeba histolytica phospholipase D, putative 0.0102 0.102 0.1512
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0205 0.0251
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni hypothetical protein 0.0727 0.8086 1
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0441 0.4854 0.6002
Schistosoma mansoni cpg binding protein 0.0028 0.019 0.0234
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) hypothetical protein 0.0028 0.0187 0.0189
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0015 0.0034 0.0042
Schistosoma mansoni nuclear hormone receptor 0.0179 0.1893 0.234
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0271 0.0363
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0016 0.0052 0.0012
Plasmodium falciparum proteasome subunit beta type-5 0.0568 0.6285 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Brugia malayi proteasome subunit alpha type 4 0.0112 0.1129 0.1353
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0978 0.1168
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Brugia malayi Phospholipase d protein 1 0.0102 0.102 0.1219
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0273 0.2957 0.3657
Schistosoma mansoni tyrosine kinase 0.0019 0.0077 0.0095
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus granulosus allatostatin A receptor 0.0075 0.072 0.069
Echinococcus granulosus 7tm_1 domain containing protein 0.0075 0.072 0.069
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0371 0.0456
Schistosoma mansoni tyrosine kinase 0.0298 0.3234 0.3999
Trypanosoma cruzi C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Schistosoma mansoni tyrosine kinase 0.0097 0.0959 0.1187
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Brugia malayi larval opioid receptor 0.0075 0.072 0.0848
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0112 0.1129 0.1737
Trypanosoma cruzi Emopamil binding protein, putative 0.0273 0.2951 0.3605
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0082 0.006
Schistosoma mansoni opsin-like receptor 0.0075 0.072 0.089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) melatonin receptor type 1A 0.0075 0.072 0.0848
Brugia malayi SRC-1 0.0047 0.0404 0.0457
Echinococcus granulosus importin subunit beta 1 0.0028 0.0187 0.0155
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0679 0.0649
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0041 0.0328 1
Loa Loa (eye worm) hypothetical protein 0.0486 0.536 0.6586
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0082
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0082 0.005
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0271 0.0332
Echinococcus multilocularis lamin b receptor 0.0047 0.0398 0.0367
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0112 0.1129 0.1351
Schistosoma mansoni coup transcription factor 0.038 0.416 0.5145
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0244 0.0257
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.1189 0.1161
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0082 0.0102
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0016 0.0052 0.0012
Onchocerca volvulus Bile acid receptor homolog 0.038 0.416 0.5093
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0025 0.0146 0.0162
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.0104 0.1879
Echinococcus granulosus sex peptide receptor 0.0075 0.072 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0371 0.0456
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0112 0.1129 0.1737
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi Proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Brugia malayi nuclear receptor RXR 0.0179 0.1893 0.2298
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0104 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.098
Toxoplasma gondii hypothetical protein 0.0041 0.0328 0.0453
Echinococcus multilocularis cpg binding protein 0.003 0.0208 0.0176
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0025 0.0146 0.0162
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.038 0.416 0.4141
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0271 0.0335
Plasmodium vivax proteasome subunit beta type-1, putative 0.0441 0.4854 0.7706
Brugia malayi hypothetical protein 0.0041 0.0328 0.0363
Echinococcus granulosus peroxidasin 0.0026 0.0162 0.013
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0273 0.2957 0.3613
Trichomonas vaginalis set domain proteins, putative 0.0236 0.2529 0.3125
Onchocerca volvulus Notchless protein homolog 0.0112 0.1129 0.1304
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Schistosoma mansoni tyrosine kinase 0.0161 0.1687 0.2087
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0089 0.0056
Schistosoma mansoni ran 0.0021 0.0103 0.0127
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0025 0.0146 0.0162
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0075 0.072 0.0848
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0179 0.1893 0.2259
Loa Loa (eye worm) hypothetical protein 0.0086 0.0836 0.0991
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0025 0.0146 0.0162
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0082 0.005
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.0809 0.0779
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0441 0.4854 0.5959
Brugia malayi CXXC zinc finger family protein 0.0028 0.019 0.0192
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.038 0.416 0.4141
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0037 0.0004
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0259 0.0276
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0219 0.0187
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.072 0.089
Trypanosoma cruzi C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0568 0.6285 1
Schistosoma mansoni importin beta-1 0.0028 0.0187 0.0231
Loa Loa (eye worm) hypothetical protein 0.024 0.2577 0.3145
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0075 0.072 0.089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.0169
Loa Loa (eye worm) norepinephrine transporter 0.024 0.2577 0.3145
Onchocerca volvulus 0.0041 0.0328 0.0303
Giardia lamblia 20S proteasome alpha subunit 5 0.0112 0.1129 0.1659
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0273 0.2957 0.3657
Onchocerca volvulus 0.002 0.0089 0.0004
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0045 0.001
Brugia malayi putative neuropeptide receptor NPR1 0.0075 0.072 0.0848
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0112 0.1129 0.1351
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0016 0.0052 0.0012
Echinococcus granulosus Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Onchocerca volvulus 0.0075 0.072 0.0794
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0112 0.1129 0.1737
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0104 0.0095
Brugia malayi G-protein coupled receptor 0.0075 0.072 0.0848
Brugia malayi Proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Echinococcus multilocularis sex peptide receptor 0.0075 0.072 0.069
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0271 0.0363
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Brugia malayi proteasome subunit beta type 1 0.0441 0.4854 0.596
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0112 0.1129 0.1396
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0102 0.1017 0.1558
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0679 0.0798
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0371 0.0456
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.072 0.069
Trichomonas vaginalis taga, putative 0.0021 0.0104 0.0125
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0112 0.1129 0.1396
Echinococcus granulosus g protein coupled receptor 0.0075 0.072 0.069
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0363
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0219 0.0187
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.0195
Schistosoma mansoni nuclear receptor 0.0179 0.1893 0.234
Brugia malayi nuclear receptor NHR-88 0.0179 0.1893 0.2298
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0219 0.0229
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.038 0.416 0.5145
Mycobacterium ulcerans hypothetical protein 0.0036 0.0271 0.0204
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0271 0.0239
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.3277 0.401
Echinococcus multilocularis g protein coupled receptor 0.0075 0.072 0.069
Schistosoma mansoni hypothetical protein 0.002 0.0089 0.011
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0102 0.1017 0.1213
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Schistosoma mansoni retinoid-x-receptor (RXR) 0.038 0.416 0.5145
Leishmania major proteasome beta 7 subunit, putative 0.0112 0.1129 0.1351
Trypanosoma brucei Emopamil binding protein, putative 0.0273 0.2951 0.3605
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0201 0.2135 0.2641
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0273 0.2957 0.3613
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0568 0.6285 0.773
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0112 0.1129 0.11
Brugia malayi proteasome subunit alpha type 3 0.0112 0.1129 0.1353
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0371 0.0414
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.0104 0.0035
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0568 0.6285 1
Plasmodium vivax importin-beta 2, putative 0.0028 0.0187 0.0228
Echinococcus granulosus g protein coupled receptor 0.0075 0.072 0.069
Trypanosoma brucei proteasome beta 7 subunit 0.0112 0.1129 0.1351
Echinococcus multilocularis protein will die slowly 0.0727 0.8086 0.808
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0025 0.0146 0.0162
Schistosoma mansoni cpg binding protein 0.003 0.0208 0.0257
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0112 0.1129 0.1687
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0162 0.0096
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0271 0.0204
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0104 0.0072
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0026 0.0158 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.0169
Brugia malayi Phospholipase D. Active site motif family protein 0.0019 0.0085 0.0063
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.072 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0026 0.0158 0.0125
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0371 0.0414
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0025 0.0146 0.0162
Echinococcus granulosus g protein coupled receptor 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus jun protein 0.0083 0.0809 0.0779
Echinococcus granulosus snurportin 1 0.0302 0.3277 0.3255
Echinococcus granulosus tyrosine protein kinase Src42A 0.0047 0.0404 0.0372
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Trypanosoma cruzi cardiolipin synthetase, putative 0.0036 0.027 0.0288
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Echinococcus multilocularis geminin 0.0168 0.1767 0.174
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.038 0.416 0.5102
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0075 0.072 0.089
Echinococcus granulosus nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Brugia malayi G protein-coupled receptor F59B2.13 0.0075 0.072 0.0848
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0112 0.1129 0.1737
Schistosoma mansoni nuclear receptor 0.0179 0.1893 0.234
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.072 0.069
Brugia malayi hypothetical protein 0.0036 0.0271 0.0293
Brugia malayi beta-NAC-like protein 0.0035 0.0259 0.0278
Loa Loa (eye worm) hypothetical protein 0.0086 0.0836 0.0991
Brugia malayi hypothetical protein 0.0179 0.1893 0.2298
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0897 1 1
Schistosoma mansoni ets-related 0.0218 0.2331 0.2883
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0112 0.1129 0.1737
Echinococcus multilocularis expressed protein 0.037 0.4051 0.4031
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0209 0.0259
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0568 0.6285 0.773
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) TK/INSR protein kinase 0.0097 0.0959 0.1144
Echinococcus granulosus neuropeptide receptor 0.0075 0.072 0.069
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0112 0.1129 0.1353
Toxoplasma gondii proteasome subunit beta type, putative 0.0568 0.6285 1
Schistosoma mansoni peroxidasin 0.0026 0.0162 0.0201
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0104 0.0086
Toxoplasma gondii proteasome subunit 0.0112 0.1129 0.1737
Brugia malayi Nuclear hormone receptor family member nhr-41 0.038 0.416 0.5102
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0127 0.0153
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.038 0.416 0.5093
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0112 0.1129 0.1687
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0271 0.0363
Loa Loa (eye worm) beta-lactamase 0.0036 0.0271 0.0293
Echinococcus multilocularis growth factor receptor bound protein 2 0.0015 0.0034 0.0002
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0047 0.0404 0.0372
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0441 0.4854 0.7692
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0019 0.0077 0.0044
Brugia malayi Serotonin receptor 0.0075 0.072 0.0848
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0201 0.2135 0.211
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0112 0.1129 0.1353
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0273 0.2957 0.4634
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.0169
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0273 0.2957 0.3655
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0103 0.0093
Brugia malayi hypothetical protein 0.0016 0.0052 0.0022
Leishmania major hypothetical protein, conserved 0.0036 0.0271 0.029
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0162 0.0158
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0731 0.8121 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.038 0.416 0.5102
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0104 0.0072
Loa Loa (eye worm) hypothetical protein 0.024 0.2577 0.3145
Loa Loa (eye worm) hypothetical protein 0.0457 0.503 0.6178
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Onchocerca volvulus 0.0727 0.8086 1
Treponema pallidum sodium- and chloride- dependent transporter 0.024 0.2577 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0101 0.0069
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.072 0.0848
Trypanosoma cruzi Emopamil binding protein, putative 0.0273 0.2951 0.3605
Brugia malayi Nuclear hormone receptor family member nhr-3 0.038 0.416 0.5102
Brugia malayi Cytochrome P450 family protein 0.0062 0.0574 0.0667
Onchocerca volvulus 0.0041 0.0328 0.0303
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0112 0.1129 0.1687
Onchocerca volvulus 0.0075 0.072 0.0794
Trichomonas vaginalis WD repeat domain, putative 0.0727 0.8086 1
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0273 0.2951 0.3605
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0082 0.006
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0026 0.0158 0.015
Trypanosoma cruzi 20S proteasome subunit 0.0273 0.2957 0.3613
Echinococcus granulosus proteasome subunit beta type 7 0.0112 0.1129 0.11
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0037 0.0045
Schistosoma mansoni Tr4/Tr2 (homologue) 0.038 0.416 0.5145
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0041 0.0328 0.0296
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0082 0.0102
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis RUN 0.002 0.0089 0.0056
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Onchocerca volvulus 0.0179 0.1893 0.2259
Brugia malayi proteasome subunit alpha type 1 0.0112 0.1129 0.1353
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0075 0.072 0.069
Brugia malayi nuclear hormone receptor 0.038 0.416 0.5102
Echinococcus multilocularis peroxidasin 0.0026 0.0162 0.013
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0162 0.0096
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0237 0.0205
Onchocerca volvulus 0.0026 0.0162 0.0096
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0273 0.2957 0.4667
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Brugia malayi Blistered cuticle protein 3 0.0026 0.0162 0.0158
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0279 0.0247
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0041 0.0328 0.0363
Schistosoma mansoni biogenic amine receptor 0.0075 0.072 0.089
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0201 0.2135 0.2598
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0075 0.072 0.069
Schistosoma mansoni myosin xvIII 0.0075 0.072 0.089
Brugia malayi nuclear hormone receptor 0.0179 0.1893 0.2298
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0082 0.005
Brugia malayi Nuclear hormone receptor family member nhr-49 0.038 0.416 0.5102
Schistosoma mansoni lipoxygenase 0.0117 0.1189 0.1471
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0045 0.0012
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0112 0.1129 0.1396
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0089 0.0056
Loa Loa (eye worm) nuclear hormone receptor 0.0179 0.1893 0.2298
Echinococcus multilocularis neuropeptide receptor A26 0.0532 0.5876 0.5862
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) proteasome subunit beta type 1 0.0441 0.4854 0.596
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0047 0.0404 0.0372
Echinococcus multilocularis allatostatin A receptor 0.0075 0.072 0.069
Brugia malayi Nuclear hormone receptor family member nhr-1 0.038 0.416 0.5102
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0187 0.0155
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0102 0.1017 0.1558
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) nuclear receptor NHR-67 0.0179 0.1893 0.2298
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Leishmania major solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Trypanosoma brucei cardiolipin synthetase, putative 0.0036 0.027 0.0288
Trichomonas vaginalis abcb9, putative 0.0021 0.0104 0.0125
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0112 0.1129 0.1737
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0112 0.1129 0.1351
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi Cytochrome P450 family protein 0.0033 0.0244 0.0259
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.072 0.089
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0089 0.0056
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0244 0.0259
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0271 0.0363
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.038 0.416 0.5102
Trypanosoma cruzi polyprenyl synthase, putative 0.0026 0.0158 0.015
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Giardia lamblia 20S proteasome alpha subunit 3 0.0112 0.1129 0.1659
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0271 0.0335
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Echinococcus granulosus alpha 1A adrenergic receptor 0.0075 0.072 0.069
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Onchocerca volvulus 0.002 0.0089 0.0004
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.2762 0.3373
Echinococcus multilocularis insulin receptor 0.0097 0.0959 0.093
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0102 0.1017 0.1419
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0112 0.1129 0.1601
Brugia malayi Melatonin receptor type 1A 0.0075 0.072 0.0848
Schistosoma mansoni gabp alpha 0.0072 0.0679 0.084
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0201 0.2135 0.2641
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0127 0.0111
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0104 0.0072
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Plasmodium falciparum transporter, putative 0.0041 0.0328 0.0453
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Schistosoma mansoni biogenic amine receptor 0.0075 0.072 0.089
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0082 0.006
Schistosoma mansoni retinoic acid receptor RXR 0.0478 0.5265 0.6511
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0104 0.0125
Leishmania major cytochrome p450-like protein 0.0025 0.0146 0.0135
Echinococcus granulosus NCK adaptor protein 0.0015 0.0034 0.0002
Schistosoma mansoni hypothetical protein 0.0168 0.1767 0.2185
Loa Loa (eye worm) hypothetical protein 0.0016 0.0052 0.0022
Brugia malayi Nuclear hormone receptor-like 1 0.0201 0.2135 0.2598
Echinococcus granulosus c src tyrosine kinase 0.0019 0.0077 0.0044
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0082 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0244 0.0257
Entamoeba histolytica hypothetical protein 0.0023 0.0127 0.0071
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0075 0.072 0.089
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0075 0.072 0.089
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Echinococcus multilocularis nuclear receptor nhr 48 0.0179 0.1893 0.1866
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0077 0.005
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.3828
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0112 0.1129 0.1659
Schistosoma mansoni microtubule-associated protein tau 0.0685 0.7601 0.94
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0244 0.0259
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0373 0.4086 0.501
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0162 0.0096
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Plasmodium vivax SET domain protein, putative 0.003 0.0209 0.0264
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0219 0.0187
Brugia malayi Nuclear hormone receptor E75 0.0179 0.1893 0.2298
Brugia malayi Serotonin receptor 0.0532 0.5876 0.7224
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0112 0.1129 0.11
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Toxoplasma gondii ABC1 family protein 0.0036 0.0271 0.0363
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0075 0.072 0.069
Echinococcus multilocularis jun protein 0.0083 0.0809 0.0779
Schistosoma mansoni multidrug resistance protein 0.0021 0.0104 0.0129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.038 0.416 0.5102
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0371 0.034
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0281 0.0249
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0161 0.1687 0.166
Leishmania major proteasome beta 2 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0244 0.0259
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0102 0.1017 0.1258
Brugia malayi ecdysteroid receptor 0.038 0.416 0.5102
Brugia malayi neuropeptide F receptor 0.0075 0.072 0.0848
Brugia malayi nuclear receptor RXR 0.0201 0.2135 0.2598
Echinococcus granulosus fmrfamide receptor 0.0075 0.072 0.069
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0398 0.0447
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0097 0.0959 0.093
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0271 0.0363
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0075 0.072 0.0848
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0112 0.1129 0.1687
Brugia malayi Furin-like cysteine rich region family protein 0.0298 0.3234 0.3957
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0271 0.0293
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.004 0.0321 0.029
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Echinococcus granulosus Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0047 0.0404 0.0372
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Echinococcus multilocularis microtubule associated protein 2 0.0685 0.7601 0.7593
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.2207 0.2687
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0273 0.2951 0.3605
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Echinococcus multilocularis proteasome subunit alpha type 2 0.0112 0.1129 0.11
Loa Loa (eye worm) hypothetical protein 0.0066 0.0618 0.0722
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0328 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Echinococcus granulosus FTZ F1 alpha 0.038 0.416 0.4141
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0112 0.1129 0.1396
Schistosoma mansoni opsin-like receptor 0.0075 0.072 0.089
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0067
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0273 0.2957 0.2934
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0363
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1737
Echinococcus granulosus neuropeptide receptor A26 0.0532 0.5876 0.5862
Plasmodium vivax proteasome subunit beta type-4, putative 0.0112 0.1129 0.1737
Schistosoma mansoni zinc finger protein 0.0179 0.1893 0.234
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Echinococcus granulosus tyrosine protein kinase Src64B 0.0047 0.0404 0.0372
Brugia malayi ABC transporter family protein 0.0021 0.0104 0.0086
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0082 0.006
Leishmania major proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni hypothetical protein 0.0125 0.1278 0.1581
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0075 0.072 0.0848
Brugia malayi Nuclear hormone receptor E75 0.0179 0.1893 0.2298
Schistosoma mansoni jun-related protein 0.0068 0.0632 0.0782
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0371 0.0414
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0219 0.0229
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0026 0.0158 0.0181
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.0809 0.0779
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi isocitrate dehydrogenase 0.0016 0.0045 0.0013
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0112 0.1129 0.1396
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0179 0.1893 0.2259
Brugia malayi Nuclear hormone receptor family member nhr-19 0.038 0.416 0.5102
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.072 0.0848
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0328 0.0405
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Brugia malayi neuropeptide F receptor 0.0075 0.072 0.0848
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0041 0.0328 0.0296
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0453
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0075 0.072 0.089
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0045 0.0012
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0201 0.2135 0.211
Echinococcus granulosus nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0075 0.072 0.0848
Loa Loa (eye worm) proteasome subunit beta type 2 0.0273 0.2957 0.3614
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0106 0.0086
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Echinococcus multilocularis ecdysone induced protein 78C 0.038 0.416 0.4141
Echinococcus granulosus geminin 0.0168 0.1767 0.174
Leishmania major farnesyl pyrophosphate synthase 0.0102 0.1017 0.1213
Brugia malayi nuclear receptor NHR-88 0.038 0.416 0.5102
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0112 0.1129 0.1687
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0019 0.0085 0.006
Echinococcus multilocularis 0.0092 0.0902 0.0873
Echinococcus granulosus protein will die slowly 0.0727 0.8086 0.808
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0112 0.1129 0.1737
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0075 0.072 0.069
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0041 0.0328 0.0296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) hypothetical protein 0.0061 0.0562 0.0652
Brugia malayi ORL1-like opioid receptor 0.0075 0.072 0.0848
Onchocerca volvulus 0.0179 0.1893 0.2259
Loa Loa (eye worm) hypothetical protein 0.024 0.2577 0.3145
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0075 0.072 0.069
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0209 0.0177
Loa Loa (eye worm) fli-1 protein 0.0218 0.2331 0.2841
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.0104 0.0035
Schistosoma mansoni adenoreceptor 0.0075 0.072 0.089
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0089 0.007
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.1278 0.125
Brugia malayi nuclear hormone receptor family member odr-7 0.0179 0.1893 0.2298
Brugia malayi Importin beta-1 subunit 0.0028 0.0187 0.0189
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0112 0.1129 0.1737
Leishmania major proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Echinococcus granulosus phospholipase D1 0.0102 0.102 0.0991
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0086 0.0836 0.1215
Echinococcus multilocularis dro:myosuppressin receptor 0.0075 0.072 0.069
Onchocerca volvulus 0.0021 0.0104 0.0024
Schistosoma mansoni tyrosine kinase 0.0161 0.1687 0.2087
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0112 0.1129 0.1737
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0103 0.007
Schistosoma mansoni amine GPCR 0.0404 0.4432 0.5481
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0271 0.0239
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.2445 0.3847
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.072 0.069
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Giardia lamblia Farnesyl diphosphate synthase 0.0102 0.1017 0.1479
Echinococcus granulosus hypothetical protein 0.076 0.8453 0.8448
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.072 0.0848
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0037 0.0004
Schistosoma mansoni trans-prenyltransferase 0.0026 0.0158 0.0195
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0102 0.1017 0.1255
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Schistosoma mansoni cpg binding protein 0.003 0.0208 0.0257
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0104 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-31 0.038 0.416 0.5102
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0281 0.0249
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0026 0.0158 0.0125
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0082 0.0102
Brugia malayi putative neuropeptide receptor 0.0075 0.072 0.0848
Trypanosoma brucei C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Loa Loa (eye worm) hypothetical protein 0.0032 0.0226 0.0238
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Brugia malayi AKH receptor 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.003 0.0209 0.0216
Plasmodium vivax proteasome subunit beta type-7, putative 0.0112 0.1129 0.1737
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0112 0.1129 0.1687
Trichomonas vaginalis abcb9, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) serotonin transporter b 0.024 0.2577 0.3145
Echinococcus granulosus insulin receptor 0.0097 0.0959 0.093
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0082 0.005
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0112 0.1129 0.11
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0259 0.0344
Echinococcus granulosus G protein coupled receptor 139 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Echinococcus multilocularis g protein coupled receptor 0.0075 0.072 0.069
Echinococcus granulosus nuclear receptor nhr 48 0.0179 0.1893 0.1866
Brugia malayi RNA, U transporter 1 0.008 0.0776 0.0917
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni tyrosine kinase 0.0047 0.0404 0.0499
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.038 0.416 0.4141
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.038 0.416 0.4141
Giardia lamblia 20S proteasome alpha subunit 6 0.0112 0.1129 0.1659
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0082 0.005
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0075 0.072 0.069
Brugia malayi Sodium:neurotransmitter symporter family protein 0.024 0.2577 0.3145
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0269 0.0287
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0259 0.0344
Schistosoma mansoni polycystin 1-related 0.002 0.0089 0.011
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0082 0.0102
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0015 0.0033 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0082 0.005
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Echinococcus granulosus dro:myosuppressin receptor 0.0075 0.072 0.069
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0045 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus multilocularis proteasome subunit beta type 7 0.0112 0.1129 0.11
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Echinococcus multilocularis phospholipase D1 0.0102 0.102 0.0991
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0112 0.1129 0.1687
Brugia malayi PXA domain containing protein 0.0023 0.0133 0.0121
Onchocerca volvulus 0.0075 0.072 0.0794
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0026 0.0158 0.0181
Onchocerca volvulus 0.003 0.0209 0.0155
Giardia lamblia Proteasome subunit beta type 2 0.0273 0.2957 0.4617
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0179 0.1893 0.1866
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Schistosoma mansoni hypothetical protein 0.0036 0.0271 0.0335
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0127 0.0153
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.0104 0.0035
Echinococcus multilocularis epidermal growth factor receptor 0.0161 0.1687 0.166
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-19 0.038 0.416 0.5102
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Echinococcus multilocularis proteasome (prosome, macropain) 0.0568 0.6285 0.6273
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0026 0.0158 0.0181
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0219 0.0229
Echinococcus multilocularis tyrosine protein kinase Srms 0.004 0.0321 0.029
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0025 0.0146 0.0162
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0271 0.0293
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0273 0.2957 0.4667
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Echinococcus granulosus serotonin transporter 0.024 0.2577 0.2553
Loa Loa (eye worm) hypothetical protein 0.0066 0.0618 0.0722
Loa Loa (eye worm) hypothetical protein 0.0315 0.3423 0.419
Brugia malayi Fli-1 protein 0.0218 0.2331 0.2841
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0082 0.005
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0026 0.0158 0.0181
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0371 0.0466
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0112 0.1129 0.1737
Toxoplasma gondii cytochrome p450 superfamily protein 0.0025 0.0146 0.0162
Plasmodium vivax proteasome subunit beta type-5, putative 0.0568 0.6285 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.019 0.0158
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0045 0.001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0045 0.001
Echinococcus multilocularis neuropeptide receptor 0.0075 0.072 0.069
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0328 0.0296
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Echinococcus multilocularis epidermal growth factor receptor 0.0298 0.3234 0.3212
Brugia malayi Cytochrome P450 family protein 0.0033 0.0244 0.0259
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0026 0.0158 0.0121
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0209 0.0259
Schistosoma mansoni hypothetical protein 0.0168 0.1767 0.2185
Brugia malayi PXA domain containing protein 0.0023 0.0133 0.0121
Leishmania major GTP-binding protein, putative 0.0021 0.0103 0.0082
Schistosoma mansoni steroid hormone receptor ad4bp 0.038 0.416 0.5145
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.038 0.416 0.5102
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0075 0.072 0.069
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0112 0.1129 0.1737
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0082 0.005
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0082 0.005
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0112 0.1129 0.1687
Echinococcus granulosus peptide allatostatin:somatostatin 0.0075 0.072 0.069
Brugia malayi proteasome subunit beta type 3 0.0112 0.1129 0.1353
Echinococcus granulosus tachykinin peptides receptor 99D 0.0075 0.072 0.069
Echinococcus multilocularis snurportin 1 0.0302 0.3277 0.3255
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0112 0.1129 0.11
Onchocerca volvulus 0.0273 0.2951 0.3581
Echinococcus granulosus proteasome subunit beta t family 0.0112 0.1129 0.11
Onchocerca volvulus 0.0026 0.0162 0.0096
Echinococcus granulosus tyrosine protein kinase Lyn 0.0047 0.0404 0.0372
Brugia malayi hypothetical protein 0.0026 0.0162 0.0158
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Brugia malayi Polyprenyl synthetase family protein 0.0026 0.0158 0.0153
Echinococcus granulosus serotonin receptor 0.0075 0.072 0.069
Echinococcus multilocularis proteasome subunit alpha type 6 0.0112 0.1129 0.11
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0179 0.1893 0.234
Echinococcus granulosus neuropeptide s receptor 0.0532 0.5876 0.5862
Schistosoma mansoni hypothetical protein 0.0302 0.3277 0.4052
Trichomonas vaginalis ran, putative 0.0021 0.0103 0.0124
Loa Loa (eye worm) hypothetical protein 0.0021 0.0101 0.0083
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0082 0.005
Leishmania major C-8 sterol isomerase-like protein 0.0731 0.8121 1
Loa Loa (eye worm) polyprenyl synthetase 0.0102 0.1017 0.1215
Brugia malayi Proteasome subunit alpha type 7-1 0.0112 0.1129 0.1353
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) doublecortin family protein 0.002 0.0089 0.0067
Onchocerca volvulus 0.0028 0.019 0.013
Schistosoma mansoni growth factor receptor-bound protein 0.0015 0.0034 0.0042
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0025 0.0146 0.0162
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0332
Echinococcus granulosus transcription factor btf3 0.0035 0.0259 0.0228
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0026 0.0158 0.0125
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0146 0.0135
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0453
Entamoeba histolytica phospholipase D, putative 0.0102 0.102 0.1512
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0271 0.0332
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0478 0.5265 0.5249
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Leishmania major proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi G protein-coupled receptor 0.0075 0.072 0.0848
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0269 0.0287
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0082 0.0099
Loa Loa (eye worm) DR-78 0.0179 0.1893 0.2298
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0271 0.029
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0102 0.1017 0.0988
Plasmodium vivax proteasome subunit beta type-2, putative 0.0273 0.2957 0.4667
Plasmodium vivax amine transporter, putative 0.0041 0.0328 0.0453
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0089 0.0056
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0082 0.005
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Toxoplasma gondii proteasome subunit alpha type, putative 0.0112 0.1129 0.1737
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0082 0.0102
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0025 0.0146 0.0162
Mycobacterium ulcerans proteasome PrcA 0.0112 0.1129 0.1601
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus tyrosine kinase 0.004 0.0321 0.029
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0371 0.0414
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0271 0.029
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0025 0.0146 0.0162
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0441 0.4854 0.5959
Schistosoma mansoni lipoxygenase 0.0082 0.0792 0.0979
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0112 0.1129 0.1737
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0978 0.1168
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Echinococcus multilocularis tyrosine protein kinase Blk 0.004 0.0321 0.029
Toxoplasma gondii proteasome beta subunit 0.0112 0.1129 0.1737
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0328 0.0296
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis NCK adaptor protein 0.0015 0.0034 0.0002
Schistosoma mansoni growth hormone secretagogue receptor 0.0075 0.072 0.089
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Leishmania major cytochrome p450-like protein 0.0033 0.0244 0.0257
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0019 0.0077 0.0095
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0328 0.0405
Loa Loa (eye worm) hypothetical protein 0.0067 0.0627 0.0733
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi tailless protein 0.0179 0.1893 0.2298
Echinococcus multilocularis 0.0025 0.0146 0.0114
Leishmania major p-glycoprotein 0.0021 0.0104 0.0083
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0021 0.0104 0.0086
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0237 0.0205
Trichomonas vaginalis abcb9, putative 0.0021 0.0104 0.0125
Brugia malayi ecdysone receptor 0.0179 0.1893 0.2298
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.072 0.069
Echinococcus multilocularis g protein coupled receptor 0.0075 0.072 0.069
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.0104 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0025 0.0146 0.0162
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0112 0.1129 0.1396
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0089 0.0056
Brugia malayi nuclear receptor NHR-67 0.0179 0.1893 0.2298
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0371 0.0459
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0047 0.0404 0.0372
Brugia malayi nuclear hormone receptor family member nhr-6 0.0179 0.1893 0.2298
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.072 0.089
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0101 0.0069
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Echinococcus multilocularis transcription factor btf3 0.0035 0.0259 0.0228
Brugia malayi protein-tyrosine kinase 0.004 0.0321 0.0355
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0269 0.0287
Echinococcus granulosus proteasome subunit alpha type 2 0.0112 0.1129 0.11
Onchocerca volvulus 0.038 0.416 0.5093
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0093
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0047 0.0404 0.0372
Plasmodium falciparum importin beta, putative 0.0028 0.0187 0.0228
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0075 0.072 0.0848
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0075 0.072 0.069
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0112 0.1129 0.1353
Brugia malayi Dopamine receptor 0.0075 0.072 0.0848
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0082
Echinococcus granulosus RUN 0.002 0.0089 0.0056
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0209 0.0177
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) TK protein kinase 0.0033 0.0237 0.0251
Schistosoma mansoni tyrosine kinase 0.0157 0.1645 0.2034
Brugia malayi bZIP transcription factor family protein 0.0083 0.0809 0.0958
Loa Loa (eye worm) SRC-1 0.0047 0.0404 0.0457
Brugia malayi Proteasome subunit alpha type 1 0.0112 0.1129 0.1353
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Brugia malayi hypothetical protein 0.0019 0.0082 0.006
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0731 0.8121 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0082 0.006
Echinococcus multilocularis neuropeptide s receptor 0.0532 0.5876 0.5862
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.072 0.089
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.072 0.089
Brugia malayi Cytochrome P450 family protein 0.0025 0.0146 0.0138
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.098
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0441 0.4854 0.5959
Loa Loa (eye worm) hypothetical protein 0.0098 0.0978 0.1168
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.072 0.089
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0259 0.0276
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Brugia malayi Protein kinase domain containing protein 0.0097 0.0959 0.1144
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Echinococcus granulosus neuropeptide receptor 0.0075 0.072 0.069
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0162 0.0096
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0277 0.2997 0.2974
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.072 0.089
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis phospholipase D 0.009 0.0886 0.0856
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0371 0.0414
Onchocerca volvulus 0.024 0.2577 0.3115
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0568 0.6285 0.773
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0112 0.1129 0.11
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0627 0.0733
Echinococcus multilocularis neuropeptide FF receptor 2 0.0075 0.072 0.069
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0082 0.006
Brugia malayi hypothetical protein 0.0065 0.0607 0.0708
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0259 0.0318
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Schistosoma mansoni nck2/grb4 0.0015 0.0034 0.0042
Leishmania major proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0082 0.0102
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0025 0.0146 0.0162
Plasmodium falciparum amino acid transporter, putative 0.0041 0.0328 0.0453
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0254 0.0311
Giardia lamblia GTOR 0.0045 0.0371 0.0434
Loa Loa (eye worm) phospholipase D 0.0019 0.0085 0.0063
Trypanosoma cruzi cardiolipin synthetase, putative 0.0036 0.027 0.0288
Schistosoma mansoni multidrug resistance protein 0.0021 0.0104 0.0129
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0112 0.1129 0.1396
Leishmania major basic transcription factor 3a, putative 0.0035 0.0259 0.0276
Echinococcus granulosus expressed protein 0.037 0.4051 0.4031
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0067
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.038 0.416 0.4141
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0321 0.029
Brugia malayi beta-lactamase family protein 0.0036 0.0271 0.0293
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0259 0.0318
Brugia malayi Pre-SET motif family protein 0.003 0.0209 0.0216
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0102 0.1017 0.1213
Onchocerca volvulus 0.0036 0.0271 0.0233
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0103 0.007
Schistosoma mansoni thyroid hormone receptor 0.0505 0.5571 0.6889
Onchocerca volvulus 0.0036 0.0271 0.0233
Schistosoma mansoni Lamin B receptor (ERG24) 0.0047 0.0398 0.0492
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0271 0.0239
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0047 0.0404 0.0372
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0179 0.1893 0.1866
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Brugia malayi Protein K4 0.0016 0.0052 0.0022
Schistosoma mansoni hypothetical protein 0.0025 0.0146 0.018
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.0125
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0371 0.034
Brugia malayi photoreceptor-specific nuclear receptor 0.038 0.416 0.5102
Schistosoma mansoni hypothetical protein 0.0067 0.0627 0.0775
Echinococcus multilocularis serotonin receptor 0.0196 0.2085 0.2059
Schistosoma mansoni thyroid hormone receptor 0.0505 0.5571 0.6889
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Brugia malayi Phospholipase D. Active site motif family protein 0.0036 0.027 0.0291
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0209 0.0264
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Brugia malayi hypothetical protein 0.0121 0.1232 0.1481
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0112 0.1129 0.1396
Brugia malayi hypothetical protein 0.002 0.0089 0.0067
Plasmodium falciparum proteasome subunit beta type-4 0.0112 0.1129 0.1737
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Schistosoma mansoni histamine h1 receptor 0.0075 0.072 0.089
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Brugia malayi Will die slowly protein 0.0727 0.8086 0.9957
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0978 0.1168
Leishmania major hypothetical protein, conserved 0.0273 0.2951 0.3605
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus granulosus lamin b receptor 0.0047 0.0398 0.0367
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Onchocerca volvulus 0.0026 0.0162 0.0096
Brugia malayi conserved hypotetical protein 0.0179 0.1893 0.2298
Leishmania major proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.0021 0.0104 0.0086
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0037 0.0003
Echinococcus multilocularis fmrfamide receptor 0.0075 0.072 0.069
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus epidermal growth factor receptor 0.0161 0.1687 0.166
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0025 0.0146 0.0135
Echinococcus granulosus neuropeptide FF receptor 2 0.0075 0.072 0.069
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0112 0.1129 0.1659
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0104 0.0095
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0104 0.0086
Onchocerca volvulus 0.0036 0.0271 0.0233
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0242 0.0317
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0112 0.1129 0.1396
Onchocerca volvulus Protein ultraspiracle homolog 0.038 0.416 0.5093
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0271 0.0204
Echinococcus granulosus GPCR family 2 0.0031 0.0219 0.0187
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Brugia malayi Doublecortin family protein 0.002 0.0089 0.0067
Echinococcus granulosus ecdysone induced protein 78C 0.038 0.416 0.4141
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Schistosoma mansoni hypothetical protein 0.0068 0.0632 0.0782
Brugia malayi follicle stimulating hormone receptor 0.0075 0.072 0.0848
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0026 0.0158 0.0121
Schistosoma mansoni biogenic amine (5HT) receptor 0.0196 0.2085 0.2578
Onchocerca volvulus Peroxidase homolog 0.0026 0.0162 0.0096
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0441 0.4854 0.7706
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0271 0.029
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0187 0.0186
Entamoeba histolytica Ran family GTPase 0.0021 0.0103 0.0033
Giardia lamblia 20S proteasome alpha subunit 7 0.0112 0.1129 0.1659
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni tyrosine kinase 0.0157 0.1645 0.2034
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0082 0.006
Brugia malayi orphan nuclear receptor NR2E1 0.0179 0.1893 0.2298
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Echinococcus multilocularis somatostatin receptor 0.0075 0.072 0.069
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0045 0.0013
Trypanosoma brucei cardiolipin synthetase 0.0036 0.027 0.0288
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Leishmania major C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0187 0.0186
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0271 0.0363
Plasmodium vivax proteasome subunit beta type-3, putative 0.0112 0.1129 0.1737
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.024 0.2577 0.3187
Loa Loa (eye worm) proteasome subunit beta type 3 0.0112 0.1129 0.1353
Brugia malayi Pre-SET motif family protein 0.0207 0.2207 0.2687
Brugia malayi Ets-domain containing protein 0.0072 0.0679 0.0798
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Brugia malayi hypothetical protein 0.0179 0.1893 0.2298
Entamoeba histolytica P-glycoprotein-1 0.0021 0.0104 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0568 0.6285 1
Loa Loa (eye worm) cytochrome P450 0.0025 0.0146 0.0138
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0112 0.1129 0.11
Onchocerca volvulus 0.0075 0.072 0.0794
Trypanosoma brucei proteasome alpha 7 subunit 0.0112 0.1129 0.1351
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.038 0.416 0.5102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0179 0.1893 0.234
Schistosoma mansoni sodium/chloride dependent transporter 0.024 0.2577 0.3187
Echinococcus multilocularis fmrfamide receptor 0.0075 0.072 0.069
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Leishmania major cytochrome p450-like protein 0.0025 0.0146 0.0135
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0026 0.0158 0.0019
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0273 0.2957 0.2934
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Brugia malayi 20S proteasome alpha5 subunit 0.0112 0.1129 0.1353
Loa Loa (eye worm) hypothetical protein 0.0196 0.2085 0.2536
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0328 0.0405
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0127 0.0153
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0026 0.0158 0.0125
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0082 0.0102
Echinococcus multilocularis tyrosine protein kinase Abl 0.0019 0.0077 0.0044
Brugia malayi Tachykinin-like peptides receptor 99D 0.0075 0.072 0.0848
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0085
Loa Loa (eye worm) cytochrome P450 family protein 0.0062 0.0574 0.0667
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0298 0.0365
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0047 0.0404 0.0372
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0179 0.1893 0.2298
Brugia malayi Nuclear hormone receptor family member nhr-25 0.038 0.416 0.5102
Brugia malayi Nuclear hormone receptor family member nhr-14 0.038 0.416 0.5102
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0319 0.0395
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0371 0.0466
Echinococcus granulosus phospholipase D 0.009 0.0886 0.0856
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis g-protein coupled receptor 0.0075 0.072 0.069
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0112 0.1129 0.1353
Brugia malayi beta-lactamase 0.0036 0.0271 0.0293
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Trypanosoma brucei C-8 sterol isomerase, putative 0.0731 0.8121 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0075 0.072 0.089
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0112 0.1129 0.1737
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.038 0.416 0.5145
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0102 0.1017 0.1419
Trichomonas vaginalis esterase, putative 0.0036 0.0271 0.0332
Toxoplasma gondii peptidase, T1 family protein 0.0112 0.1129 0.1737
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0259 0.0278
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0075 0.072 0.069
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0025 0.0146 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0075 0.072 0.069
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0112 0.1129 0.11
Schistosoma mansoni smdr2 0.0021 0.0104 0.0129
Leishmania major proteasome beta 5 subunit, putative 0.0568 0.6285 0.773
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0112 0.1129 0.1687
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis G protein coupled receptor 139 0.0075 0.072 0.069
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.072 0.069
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0259 0.0285
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0026 0.0158 0.0019
Giardia lamblia Proteasome subunit beta type 1 0.0441 0.4854 0.7684
Toxoplasma gondii hypothetical protein 0.0041 0.0328 0.0453
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0244 0.016
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0271 0.0363
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0097 0.0959 0.093
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0279 0.0247
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0328 0.0453
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0209 0.0259
Onchocerca volvulus 0.0236 0.2529 0.3055
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0025 0.0146 0.0162
Leishmania major importin beta-1 subunit, putative 0.0023 0.0127 0.0111
Brugia malayi steroid hormone receptor 0.038 0.416 0.5102
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.1767 0.2102
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Schistosoma mansoni RAR-like nuclear receptor 0.038 0.416 0.5145
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Echinococcus granulosus biogenic amine 5HT receptor 0.0196 0.2085 0.2059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0112 0.1129 0.1737
Echinococcus granulosus tyrosine protein kinase Blk 0.004 0.0321 0.029
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.019 0.0192
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0371 0.0417
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.038 0.416 0.5145
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni ran 0.0021 0.0103 0.0127
Brugia malayi Peroxidasin 0.0026 0.0162 0.0158
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0045 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0075 0.072 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0166 0.0201
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus Proteasome subunit alpha beta 0.0112 0.1129 0.11
Echinococcus granulosus cpg binding protein 0.003 0.0208 0.0176
Plasmodium vivax proteasome subunit beta type-6, putative 0.0112 0.1129 0.1737
Brugia malayi cytochrome P450 0.0025 0.0146 0.0138
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus multilocularis thyroid hormone receptor alpha 0.0505 0.5571 0.5556
Brugia malayi hypothetical protein 0.0201 0.2135 0.2598
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0319 0.0395
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Brugia malayi Proteasome A-type and B-type family protein 0.0568 0.6285 0.773
Onchocerca volvulus Neuropeptide F receptor homolog 0.0075 0.072 0.0794
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0219 0.0187
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0271 0.0204
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.038 0.416 0.5102
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0082 0.006
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0146 0.0135
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0271 0.0239
Leishmania major proteasome beta 2 subunit, putative 0.0273 0.2957 0.3613
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0166 0.0201
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.038 0.416 0.5102
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0112 0.1129 0.1351
Loa Loa (eye worm) TK/EGFR protein kinase 0.0298 0.3234 0.3957
Schistosoma mansoni growth factor receptor-bound protein 0.0015 0.0034 0.0042
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0273 0.2951 0.3605
Loa Loa (eye worm) polyprenyl synthetase 0.0026 0.0158 0.0153
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0075 0.072 0.089
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0026 0.0158 0.0153
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Loa Loa (eye worm) hypothetical protein 0.0731 0.8121 1
Echinococcus granulosus subfamily T1A non peptidase ue 0.0112 0.1129 0.11
Schistosoma mansoni transcription factor btf3 0.0035 0.0259 0.0321
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Schistosoma mansoni nuclear hormone receptor 0.038 0.416 0.5145
Onchocerca volvulus 0.0041 0.0328 0.0303
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0112 0.1129 0.1737
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0112 0.1129 0.1687
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0016 0.0052 0.0065
Schistosoma mansoni tyrosine kinase 0.0047 0.0404 0.0499
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0271 0.0335
Brugia malayi Nuclear hormone receptor-like 1 0.0201 0.2135 0.2598
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.038 0.416 0.5145
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0019 0.0077 0.0044
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0112 0.1129 0.1353
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0082 0.0102
Brugia malayi hypothetical protein 0.002 0.0089 0.0067
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0082 0.005
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0112 0.1129 0.11
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0075 0.072 0.089
Brugia malayi multidrug resistance protein 3 0.0021 0.0104 0.0086
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.072 0.069
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0112 0.1129 0.1737
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0187 0.0228
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0026 0.0158 0.0153
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0026 0.0158 0.0019
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Brugia malayi Dopamine receptor protein 2 0.0075 0.072 0.0848
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0453
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Leishmania major proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0112 0.1129 0.1351
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0568 0.6285 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0025 0.0146 0.0162
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0025 0.0146 0.0162
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.1278 0.125
Brugia malayi Proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0259 0.0276
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0045 0.0013
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Giardia lamblia 20S proteasome alpha subunit 4 0.0112 0.1129 0.1659
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0102 0.1017 0.1558
Schistosoma mansoni rab6-interacting 0.002 0.0089 0.011
Brugia malayi Nuclear hormone receptor family member nhr-40 0.038 0.416 0.5102
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0441 0.4854 0.4837
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0082 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Schistosoma mansoni nuclear hormone receptor 0.0179 0.1893 0.234
Brugia malayi proteasome subunit alpha type 2 0.0112 0.1129 0.1353
Echinococcus multilocularis G-protein coupled receptor, putative 0.0075 0.072 0.069
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0112 0.1129 0.1659
Echinococcus multilocularis serotonin transporter 0.024 0.2577 0.2553
Loa Loa (eye worm) steroid hormone receptor 0.038 0.416 0.5102
Leishmania major polyprenyl synthase, putative 0.0026 0.0158 0.015
Echinococcus granulosus epidermal growth factor receptor 0.0298 0.3234 0.3212
Brugia malayi Polyprenyl synthetase family protein 0.0102 0.1017 0.1215
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0104 0.0072
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Mycobacterium ulcerans beta-lactamase 0.0036 0.0271 0.0204
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0103 0.0093
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Schistosoma mansoni tyrosine kinase 0.0097 0.0959 0.1187
Loa Loa (eye worm) WD40 repeat protein 0.0727 0.8086 0.9957
Schistosoma mansoni neuropeptide f receptor 76f 0.0075 0.072 0.089
Schistosoma mansoni nuclear receptor nhr-48 0.0179 0.1893 0.234
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0041 0.0328 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0169 0.0205
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.4451 0.4433
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0271 0.0363
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.0281 0.0305
Echinococcus granulosus microtubule associated protein 2 0.0685 0.7601 0.7593
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0041 0.0328 0.0296
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0075 0.072 0.0848
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Brugia malayi Nuclear hormone receptor-like 1 0.038 0.416 0.5102
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0075 0.072 0.0848
Entamoeba histolytica hypothetical protein 0.0035 0.0259 0.0285
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0112 0.1129 0.1351
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.072 0.069
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0259 0.0344
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0075 0.072 0.0848
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0102 0.1017 0.1255
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Echinococcus granulosus thyroid hormone receptor alpha 0.0179 0.1893 0.1866
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.072 0.069
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Onchocerca volvulus Peroxidase homolog 0.0026 0.0162 0.0096
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0082 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.038 0.416 0.5102
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Trypanosoma brucei proteasome beta 6 subunit 0.0441 0.4854 0.5959
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0104 0.0035
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0332
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0244 0.0257
Schistosoma mansoni adapter molecule crk 0.0015 0.0034 0.0042
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Mycobacterium leprae Probable lipase LipE 0.0036 0.0271 0.0204
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0104 0.0095
Schistosoma mansoni phospholipase D 0.0102 0.102 0.1262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0332
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0209 0.0259
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0025 0.0146 0.0162
Schistosoma mansoni glutathione synthetase 0.0026 0.0158 0.0195
Brugia malayi proteasome subunit alpha type 6 0.0112 0.1129 0.1353
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0036 0.027 0.036
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.0125
Schistosoma mansoni hypothetical protein 0.0406 0.4451 0.5505
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0089 0.0056
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0047 0.0404 0.0372
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.0104 0.0083
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0112 0.1129 0.11
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0112 0.1129 0.1687
Brugia malayi Dopamine receptor protein 1 0.0075 0.072 0.0848
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0133 0.0121
Brugia malayi Ets-domain containing protein 0.0072 0.0679 0.0798
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0563 0.0696
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0075 0.072 0.0794
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0679 0.0649
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0102 0.1017 0.1255
Echinococcus granulosus orexin receptor type 2 0.0075 0.072 0.069
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Brugia malayi G-protein coupled receptor 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0112 0.1129 0.1737
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0371 0.0414
Echinococcus granulosus growth factor receptor bound protein 2 0.0015 0.0034 0.0002
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0082 0.005
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0209 0.0177
Onchocerca volvulus 0.0075 0.072 0.0794
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0025 0.0146 0.0162
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0568 0.6285 0.773
Echinococcus granulosus somatostatin receptor 0.0075 0.072 0.069
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0169 0.0205
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0025 0.0146 0.0135
Brugia malayi Steroid receptor seven-up type 2 0.038 0.416 0.5102
Brugia malayi hypothetical protein 0.0201 0.2135 0.2598
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0082 0.0102
Entamoeba histolytica protein kinase, putative 0.0033 0.0237 0.0249
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Echinococcus granulosus proteasome subunit alpha type 6 0.0112 0.1129 0.11
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Giardia lamblia 20S proteasome alpha subunit 1 0.0112 0.1129 0.1659
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0102 0.1017 0.0988
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0112 0.1129 0.1737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.072 0.069
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0398 0.0447
Echinococcus multilocularis conserved hypothetical protein 0.0685 0.7601 0.7593
Brugia malayi Tyrosine-protein kinase abl-1 0.0019 0.0077 0.0053
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0045 0.0055
Echinococcus granulosus g-protein coupled receptor 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0486 0.536 0.6586
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0112 0.1129 1
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0441 0.4854 0.4837
Schistosoma mansoni rab6-interacting 0.002 0.0089 0.011
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0026 0.0158 0.0121
Onchocerca volvulus 0.0065 0.0607 0.0652

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) = 3226 Cardiotoxicity by a neonatal rat heart myocyte assay ChEMBL. 8648600
IC50 (functional) = 2.9 nM Inhibitory activity against sensitive L1210 cell lines ChEMBL. 8648600
IC50 (functional) = 2.9 nM Inhibitory activity against sensitive L1210 cell lines ChEMBL. 8648600
IC50 (functional) = 6.8 nM Inhibitory activity against resistant murine leukemia L1210 cell lines. ChEMBL. 8648600
IC50 (functional) = 6.8 nM Inhibitory activity against resistant murine leukemia L1210 cell lines. ChEMBL. 8648600
IC50 (functional) = 29 nM Inhibitory activity against AUC375 cell line ChEMBL. 8648600
IC50 (functional) = 69 nM An average for IC50 values in the two solid tumor cell lines and sensitive L1210 leukemia cell line. ChEMBL. 8648600
IC50 (functional) = 103 nM An average for IC50 values in the two solid tumor cell lines. ChEMBL. 8648600
IC50 (functional) = 176 nM Inhibitory activity against OVCAR-3 cell line ChEMBL. 8648600
IC50 (functional) = 176 nM Inhibitory activity against OVCAR-3 cell line ChEMBL. 8648600
Toxicity ratio (functional) = 47 Toxicity ratio determined by the quotient of IC50 values in the mycocytes divided by the average value in the three tumor lines. ChEMBL. 8648600

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 8648600
Mus musculus ChEMBL23 8648600

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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