Detailed information for compound 58701

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 438.95 | Formula: C24H27ClN4O2
  • H donors: 1 H acceptors: 2 LogP: 4.09 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCNc1ccc2c3c1cc1c(Cl)cccc1c3c(=O)n(c2=O)CCN(C)C)C
  • InChi: 1S/C24H27ClN4O2/c1-27(2)11-10-26-20-9-8-16-21-18(20)14-17-15(6-5-7-19(17)25)22(21)24(31)29(23(16)30)13-12-28(3)4/h5-9,14,26H,10-13H2,1-4H3
  • InChiKey: IQCFWJIJLFBEFD-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Loa Loa (eye worm) WD40 repeat protein 0.0727 0.8086 0.9957
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0332
Echinococcus granulosus Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0209 0.0177
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0082 0.006
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0112 0.1129 0.1659
Trypanosoma brucei proteasome beta 7 subunit 0.0112 0.1129 0.1351
Schistosoma mansoni myosin xvIII 0.0075 0.072 0.089
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Brugia malayi Proteasome A-type and B-type family protein 0.0568 0.6285 0.773
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0097 0.0959 0.093
Onchocerca volvulus 0.038 0.416 0.5093
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0075 0.072 0.089
Onchocerca volvulus 0.0026 0.0162 0.0096
Echinococcus multilocularis allatostatin A receptor 0.0075 0.072 0.069
Mycobacterium ulcerans proteasome PrcA 0.0112 0.1129 0.1601
Giardia lamblia GTOR 0.0045 0.0371 0.0434
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0025 0.0146 0.0162
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0179 0.1893 0.1866
Brugia malayi Tyrosine-protein kinase abl-1 0.0019 0.0077 0.0053
Brugia malayi AKH receptor 0.0075 0.072 0.0848
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0075 0.072 0.069
Echinococcus multilocularis tyrosine protein kinase Blk 0.004 0.0321 0.029
Brugia malayi Nuclear hormone receptor family member nhr-3 0.038 0.416 0.5102
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Leishmania major farnesyl pyrophosphate synthase 0.0102 0.1017 0.1213
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Echinococcus granulosus FTZ F1 alpha 0.038 0.416 0.4141
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0082 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Echinococcus granulosus epidermal growth factor receptor 0.0298 0.3234 0.3212
Plasmodium vivax SET domain protein, putative 0.003 0.0209 0.0264
Echinococcus granulosus phospholipase d3 0.0019 0.0085 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0319 0.0395
Onchocerca volvulus 0.0236 0.2529 0.3055
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0025 0.0146 0.0135
Brugia malayi putative neuropeptide receptor 0.0075 0.072 0.0848
Echinococcus multilocularis growth factor receptor bound protein 2 0.0015 0.0034 0.0002
Echinococcus granulosus importin subunit beta 1 0.0028 0.0187 0.0155
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0082 0.005
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0273 0.2957 0.4667
Brugia malayi larval opioid receptor 0.0075 0.072 0.0848
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0112 0.1129 0.11
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.4451 0.4433
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0187 0.0186
Brugia malayi proteasome subunit alpha type 2 0.0112 0.1129 0.1353
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0332
Loa Loa (eye worm) hypothetical protein 0.0021 0.0104 0.0086
Giardia lamblia 20S proteasome alpha subunit 5 0.0112 0.1129 0.1659
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni ran 0.0021 0.0103 0.0127
Schistosoma mansoni amine GPCR 0.0404 0.4432 0.5481
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.0104 0.0035
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) hypothetical protein 0.0021 0.0104 0.0086
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0075 0.072 0.089
Echinococcus multilocularis neuropeptide s receptor 0.0532 0.5876 0.5862
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0082 0.005
Echinococcus granulosus insulin receptor 0.0097 0.0959 0.093
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0281 0.0249
Schistosoma mansoni smdr2 0.0021 0.0104 0.0129
Leishmania major sterol C-24 reductase, putative 0.0047 0.0398 0.0447
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.072 0.069
Schistosoma mansoni growth factor receptor-bound protein 0.0015 0.0034 0.0042
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0112 0.1129 0.1351
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0179 0.1893 0.1866
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0112 0.1129 0.1737
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0082 0.005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.038 0.416 0.5102
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0112 0.1129 0.1737
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0089 0.0056
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0082 0.005
Schistosoma mansoni opsin-like receptor 0.0075 0.072 0.089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0195 0.0237
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0112 0.1129 0.1687
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus granulosus g protein coupled receptor 0.0075 0.072 0.069
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0041 0.0328 0.0296
Schistosoma mansoni tyrosine kinase 0.0019 0.0077 0.0095
Brugia malayi Nuclear hormone receptor E75 0.0179 0.1893 0.2298
Brugia malayi proteasome subunit alpha type 1 0.0112 0.1129 0.1353
Brugia malayi proteasome subunit alpha type 4 0.0112 0.1129 0.1353
Loa Loa (eye worm) hypothetical protein 0.024 0.2577 0.3145
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0104 0.0095
Plasmodium falciparum transporter, putative 0.0041 0.0328 0.0453
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Plasmodium vivax proteasome subunit beta type-7, putative 0.0112 0.1129 0.1737
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis geminin 0.0168 0.1767 0.174
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0089 0.007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.0104 0.0095
Brugia malayi beta-lactamase 0.0036 0.0271 0.0293
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Brugia malayi ecdysteroid receptor 0.038 0.416 0.5102
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.0104 0.0083
Schistosoma mansoni tyrosine kinase 0.0161 0.1687 0.2087
Schistosoma mansoni nck2/grb4 0.0015 0.0034 0.0042
Brugia malayi tailless protein 0.0179 0.1893 0.2298
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0441 0.4854 0.6002
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0371 0.0466
Echinococcus granulosus transcription factor btf3 0.0035 0.0259 0.0228
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0273 0.2957 0.4634
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0075 0.072 0.089
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0187 0.0155
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0082 0.005
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0103 0.007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1737
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0271 0.0363
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0103 0.0093
Brugia malayi Peroxidasin 0.0026 0.0162 0.0158
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi hypothetical protein 0.0201 0.2135 0.2598
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0112 0.1129 0.1737
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Brugia malayi neuropeptide F receptor 0.0075 0.072 0.0848
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0075 0.072 0.069
Onchocerca volvulus 0.0075 0.072 0.0794
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0082 0.006
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0568 0.6285 0.7773
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Brugia malayi Importin beta-1 subunit 0.0028 0.0187 0.0189
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0371 0.0414
Schistosoma mansoni phospholipase D 0.0102 0.102 0.1262
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0112 0.1129 0.1737
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0102 0.1017 0.1558
Toxoplasma gondii proteasome subunit 0.0112 0.1129 0.1737
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0162 0.0096
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi photoreceptor-specific nuclear receptor 0.038 0.416 0.5102
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.2762 0.3373
Loa Loa (eye worm) hypothetical protein 0.0061 0.0562 0.0652
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0112 0.1129 0.1687
Schistosoma mansoni opsin-like receptor 0.0075 0.072 0.089
Schistosoma mansoni nuclear receptor 0.0179 0.1893 0.234
Brugia malayi Nuclear hormone receptor family member nhr-19 0.038 0.416 0.5102
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Schistosoma mansoni tyrosine kinase 0.0161 0.1687 0.2087
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Loa Loa (eye worm) hypothetical protein 0.0196 0.2085 0.2536
Toxoplasma gondii proteasome subunit beta type, putative 0.0568 0.6285 1
Loa Loa (eye worm) hypothetical protein 0.0731 0.8121 1
Echinococcus multilocularis cpg binding protein 0.003 0.0208 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.038 0.416 0.5102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) solute carrier family 6 member 4 0.024 0.2577 0.3145
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0219 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Trypanosoma cruzi C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Echinococcus multilocularis thyroid hormone receptor alpha 0.0505 0.5571 0.5556
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0104 0.0072
Toxoplasma gondii cytochrome p450 superfamily protein 0.0025 0.0146 0.0162
Echinococcus multilocularis neuropeptide receptor 0.0075 0.072 0.069
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0045 0.001
Leishmania major cytochrome p450-like protein 0.0025 0.0146 0.0135
Brugia malayi hypothetical protein 0.0019 0.0082 0.006
Schistosoma mansoni jun-related protein 0.0068 0.0632 0.0782
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0978 0.1168
Giardia lamblia Proteasome subunit beta type 3 0.0112 0.1129 0.1659
Brugia malayi Polyprenyl synthetase family protein 0.0102 0.1017 0.1215
Leishmania major proteasome beta 7 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0016 0.0052 0.0065
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0568 0.6285 1
Schistosoma mansoni nuclear receptor 0.0179 0.1893 0.234
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0219 0.0187
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0271 0.0239
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0102 0.1017 0.1213
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0082 0.005
Echinococcus multilocularis G protein coupled receptor 139 0.0075 0.072 0.069
Brugia malayi Cytochrome P450 family protein 0.0025 0.0146 0.0138
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0112 0.1129 0.1601
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus granulosus phospholipase D 0.009 0.0886 0.0856
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis proteasome subunit beta type 6 0.0112 0.1129 0.11
Brugia malayi nuclear receptor NHR-88 0.038 0.416 0.5102
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0041 0.0328 1
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0102 0.1017 0.1419
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0568 0.6285 0.773
Brugia malayi ORL1-like opioid receptor 0.0075 0.072 0.0848
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0047 0.0404 0.0372
Brugia malayi GnHR receptor homolog 0.0075 0.072 0.0848
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.038 0.416 0.5145
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni opsin-like receptor 0.0075 0.072 0.089
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0237 0.0205
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0273 0.2951 0.3605
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.0104 0.0035
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0187 0.0228
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Trichomonas vaginalis abcb9, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Schistosoma mansoni zinc finger protein 0.0179 0.1893 0.234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi nuclear hormone receptor 0.038 0.416 0.5102
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0104 0.0035
Entamoeba histolytica hypothetical protein 0.0023 0.0127 0.0071
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.072 0.0848
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0016 0.0052 0.0012
Echinococcus granulosus Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Plasmodium falciparum importin beta, putative 0.0028 0.0187 0.0228
Loa Loa (eye worm) hypothetical protein 0.0196 0.2085 0.2536
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0075 0.072 0.089
Plasmodium vivax proteasome subunit beta type-5, putative 0.0568 0.6285 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.038 0.416 0.5102
Toxoplasma gondii proteasome subunit alpha type, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Echinococcus multilocularis neuropeptide FF receptor 2 0.0075 0.072 0.069
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Brugia malayi Protein kinase domain containing protein 0.0097 0.0959 0.1144
Trypanosoma cruzi 20S proteasome subunit 0.0273 0.2957 0.3613
Brugia malayi Dopamine receptor protein 1 0.0075 0.072 0.0848
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0082 0.005
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0112 0.1129 0.1687
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0102 0.1017 0.1255
Echinococcus granulosus somatostatin receptor 0.0075 0.072 0.069
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Leishmania major polyprenyl synthase, putative 0.0026 0.0158 0.015
Schistosoma mansoni tyrosine kinase 0.0157 0.1645 0.2034
Loa Loa (eye worm) cytochrome P450 0.0025 0.0146 0.0138
Onchocerca volvulus 0.0041 0.0328 0.0303
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) polyprenyl synthetase 0.0026 0.0158 0.0153
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0112 0.1129 0.1687
Brugia malayi hypothetical protein 0.002 0.0089 0.0067
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0075 0.072 0.0848
Schistosoma mansoni nuclear hormone receptor 0.0179 0.1893 0.234
Schistosoma mansoni histamine h1 receptor 0.0075 0.072 0.089
Onchocerca volvulus Peroxidase homolog 0.0026 0.0162 0.0096
Onchocerca volvulus 0.0075 0.072 0.0794
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0179 0.1893 0.234
Onchocerca volvulus 0.0041 0.0328 0.0303
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.072 0.089
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Schistosoma mansoni hypothetical protein 0.0406 0.4451 0.5505
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Brugia malayi Proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0102 0.1017 0.1213
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0271 0.029
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0026 0.0158 0.0019
Trypanosoma cruzi Emopamil binding protein, putative 0.0273 0.2951 0.3605
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0568 0.6285 0.7772
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.038 0.416 0.5102
Leishmania major proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Plasmodium vivax amine transporter, putative 0.0041 0.0328 0.0453
Echinococcus granulosus epidermal growth factor receptor 0.0161 0.1687 0.166
Schistosoma mansoni polycystin 1-related 0.002 0.0089 0.011
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0679 0.0649
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0104 0.0072
Giardia lamblia 20S proteasome alpha subunit 1 0.0112 0.1129 0.1659
Loa Loa (eye worm) hypothetical protein 0.0032 0.0226 0.0238
Echinococcus multilocularis sex peptide receptor 0.0075 0.072 0.069
Onchocerca volvulus 0.0075 0.072 0.0794
Mycobacterium ulcerans beta-lactamase 0.0036 0.0271 0.0204
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0563 0.0696
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Leishmania major solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Echinococcus granulosus proteasome subunit alpha type 2 0.0112 0.1129 0.11
Plasmodium vivax proteasome subunit beta type-3, putative 0.0112 0.1129 0.1737
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.038 0.416 0.4141
Loa Loa (eye worm) hypothetical protein 0.0066 0.0618 0.0722
Loa Loa (eye worm) hypothetical protein 0.0315 0.3423 0.419
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0082 0.005
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.038 0.416 0.5145
Onchocerca volvulus Bile acid receptor homolog 0.038 0.416 0.5093
Loa Loa (eye worm) hypothetical protein 0.0457 0.503 0.6178
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0041 0.0328 0.0296
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0273 0.2951 0.3605
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0371 0.034
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0082 0.0102
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0041 0.0328 0.0296
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0244 0.0259
Leishmania major cytochrome p450-like protein 0.0025 0.0146 0.0135
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0209 0.0259
Brugia malayi Cytochrome P450 family protein 0.0062 0.0574 0.0667
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0371 0.0414
Brugia malayi Dopamine receptor 0.0075 0.072 0.0848
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0082
Brugia malayi Phospholipase d protein 1 0.0102 0.102 0.1219
Loa Loa (eye worm) hypothetical protein 0.024 0.2577 0.3145
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0075 0.072 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0169 0.0205
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0025 0.0146 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0166 0.0201
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0025 0.0146 0.0162
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi proteasome subunit alpha type 3 0.0112 0.1129 0.1353
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Onchocerca volvulus 0.003 0.0209 0.0155
Echinococcus multilocularis neuropeptide receptor A26 0.0532 0.5876 0.5862
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.072 0.069
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Echinococcus granulosus growth factor receptor bound protein 2 0.0015 0.0034 0.0002
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Schistosoma mansoni hypothetical protein 0.0302 0.3277 0.4052
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0978 0.1168
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0371 0.0417
Leishmania major proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0045 0.001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.038 0.416 0.5102
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0041 0.0328 0.0363
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0112 0.1129 0.11
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Brugia malayi Cytochrome P450 family protein 0.0033 0.0244 0.0259
Echinococcus multilocularis nuclear receptor nhr 48 0.0179 0.1893 0.1866
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.0104 0.1879
Entamoeba histolytica phospholipase D, putative 0.0102 0.102 0.1512
Loa Loa (eye worm) hypothetical protein 0.0086 0.0836 0.0991
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0041 0.0328 0.0296
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0103 0.0093
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0112 0.1129 0.1351
Trichomonas vaginalis abcb9, putative 0.0021 0.0104 0.0125
Schistosoma mansoni nuclear hormone receptor 0.0179 0.1893 0.234
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0104 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0082 0.005
Brugia malayi multidrug resistance protein 3 0.0021 0.0104 0.0086
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0026 0.0158 0.0121
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Onchocerca volvulus 0.002 0.0089 0.0004
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0112 0.1129 0.1737
Brugia malayi Sodium:neurotransmitter symporter family protein 0.024 0.2577 0.3145
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Brugia malayi Proteasome subunit alpha type 7-1 0.0112 0.1129 0.1353
Brugia malayi RE15519p 0.0075 0.072 0.0848
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0025 0.0146 0.0162
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Leishmania major hypothetical protein, conserved 0.0273 0.2951 0.3605
Onchocerca volvulus 0.0075 0.072 0.0794
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0112 0.1129 0.1737
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0075 0.072 0.069
Brugia malayi proteasome subunit alpha type 6 0.0112 0.1129 0.1353
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0082 0.006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0026 0.0158 0.0181
Trichomonas vaginalis taga, putative 0.0021 0.0104 0.0125
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0082 0.0102
Loa Loa (eye worm) hypothetical protein 0.0021 0.0101 0.0083
Echinococcus granulosus biogenic amine 5HT receptor 0.0196 0.2085 0.2059
Echinococcus multilocularis GPCR, family 2 0.0031 0.0219 0.0187
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0371 0.0459
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0371 0.0456
Brugia malayi beta-NAC-like protein 0.0035 0.0259 0.0278
Echinococcus granulosus RUN 0.002 0.0089 0.0056
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0271 0.0332
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0025 0.0146 0.0162
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0259 0.0276
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0209 0.0177
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0371 0.034
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0104 0.0086
Brugia malayi hypothetical protein 0.0019 0.0082 0.006
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0016 0.0052 0.0019
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0244 0.0259
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0568 0.6285 0.773
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Brugia malayi isocitrate dehydrogenase 0.0016 0.0045 0.0013
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0104 0.0095
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Mycobacterium ulcerans proteasome PrcB 0.0568 0.6285 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0271 0.0332
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0015 0.0033 0.0037
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0271 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0259 0.0318
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0026 0.0158 0.0181
Schistosoma mansoni rab6-interacting 0.002 0.0089 0.011
Loa Loa (eye worm) hypothetical protein 0.0486 0.536 0.6586
Echinococcus multilocularis tyrosine protein kinase Srms 0.004 0.0321 0.029
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0026 0.0158 0.0181
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Echinococcus multilocularis microtubule associated protein 2 0.0685 0.7601 0.7593
Giardia lamblia Farnesyl diphosphate synthase 0.0102 0.1017 0.1479
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0441 0.4854 0.4837
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0089 0.0056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Schistosoma mansoni RAR-like nuclear receptor 0.038 0.416 0.5145
Brugia malayi Nuclear hormone receptor family member nhr-1 0.038 0.416 0.5102
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.0281 0.0305
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Leishmania major hypothetical protein, conserved 0.0036 0.0271 0.029
Loa Loa (eye worm) hypothetical protein 0.0031 0.0219 0.0229
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0112 0.1129 0.1687
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0112 0.1129 0.1737
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0209 0.0177
Onchocerca volvulus 0.0727 0.8086 1
Loa Loa (eye worm) nuclear hormone receptor 0.0179 0.1893 0.2298
Schistosoma mansoni multidrug resistance protein 0.0021 0.0104 0.0129
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Brugia malayi hypothetical protein 0.0201 0.2135 0.2598
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0271 0.029
Schistosoma mansoni hypothetical protein 0.0068 0.0632 0.0782
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0075 0.072 0.069
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0082 0.005
Onchocerca volvulus 0.0179 0.1893 0.2259
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Brugia malayi proteasome subunit beta type 2 0.0273 0.2957 0.3614
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Schistosoma mansoni hypothetical protein 0.0067 0.0627 0.0775
Onchocerca volvulus 0.002 0.0089 0.0004
Onchocerca volvulus 0.0036 0.0271 0.0233
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) phospholipase D 0.0019 0.0085 0.0063
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis orexin receptor type 2 0.0075 0.072 0.069
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0146 0.0135
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0441 0.4854 0.6001
Onchocerca volvulus 0.0036 0.0271 0.0233
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0328 0.0453
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0112 0.1129 0.11
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.038 0.416 0.4141
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0082 0.006
Schistosoma mansoni neuropeptide f receptor 76f 0.0075 0.072 0.089
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0568 0.6285 0.773
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0259 0.0278
Brugia malayi Nuclear hormone receptor family member nhr-14 0.038 0.416 0.5102
Schistosoma mansoni sodium-dependent amino acid transporter 0.0041 0.0328 0.0405
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.038 0.416 0.5102
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus GPCR family 2 0.0031 0.0219 0.0187
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0259 0.0344
Loa Loa (eye worm) polyprenyl synthetase 0.0102 0.1017 0.1215
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.0809 0.0779
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0082 0.006
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0281 0.0249
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1351
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0026 0.0158 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.038 0.416 0.5102
Loa Loa (eye worm) proteasome subunit beta type 3 0.0112 0.1129 0.1353
Loa Loa (eye worm) proteasome subunit beta type 2 0.0273 0.2957 0.3614
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0371 0.0414
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0627 0.0733
Brugia malayi G-protein coupled receptor 0.0075 0.072 0.0848
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0244 0.0257
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0112 0.1129 0.1659
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0102 0.1017 0.1258
Schistosoma mansoni thyroid hormone receptor 0.0505 0.5571 0.6889
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.038 0.416 0.5145
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.038 0.416 0.4141
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0568 0.6285 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0328 0.0405
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0201 0.2135 0.2598
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0273 0.2957 0.3657
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0089 0.0056
Loa Loa (eye worm) hypothetical protein 0.0067 0.0627 0.0733
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0037 0.0003
Schistosoma mansoni trans-prenyltransferase 0.0026 0.0158 0.0195
Plasmodium vivax proteasome subunit beta type-2, putative 0.0273 0.2957 0.4667
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus allatostatin A receptor 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Schistosoma mansoni tyrosine kinase 0.0298 0.3234 0.3999
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0041 0.0328 0.0296
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0179 0.1893 0.1866
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Brugia malayi nuclear receptor NHR-67 0.0179 0.1893 0.2298
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0146 0.0135
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0026 0.0158 0.0125
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0112 0.1129 0.1737
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0112 0.1129 0.1687
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Plasmodium falciparum amino acid transporter, putative 0.0041 0.0328 0.0453
Plasmodium vivax cardiolipin synthetase, putative 0.0016 0.0052 0.0012
Brugia malayi SRC-1 0.0047 0.0404 0.0457
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0371 0.0414
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0179 0.1893 0.1866
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0075 0.072 0.069
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0269 0.0287
Loa Loa (eye worm) TK/INSR protein kinase 0.0097 0.0959 0.1144
Loa Loa (eye worm) cytochrome P450 family protein 0.0062 0.0574 0.0667
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0082 0.005
Schistosoma mansoni hypothetical protein 0.0025 0.0146 0.018
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0269 0.0287
Echinococcus granulosus proteasome subunit alpha type 6 0.0112 0.1129 0.11
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0978 0.1168
Schistosoma mansoni tyrosine kinase 0.0097 0.0959 0.1187
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Brugia malayi Proteasome subunit alpha type 1 0.0112 0.1129 0.1353
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.098
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.038 0.416 0.5145
Brugia malayi putative neuropeptide receptor NPR1 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.0373 0.4086 0.501
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0363
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.072 0.069
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0219 0.0187
Brugia malayi nuclear receptor RXR 0.0201 0.2135 0.2598
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Brugia malayi CXXC zinc finger family protein 0.0028 0.019 0.0192
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1869 0.2308
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0273 0.2957 0.3655
Echinococcus granulosus 7TM GPCR rhodopsin 0.0075 0.072 0.069
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0271 0.029
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Brugia malayi Phospholipase D. Active site motif family protein 0.0036 0.027 0.0291
Schistosoma mansoni neuropeptide receptor 0.0075 0.072 0.089
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0025 0.0146 0.0162
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0082 0.0102
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Brugia malayi Ets-domain containing protein 0.0072 0.0679 0.0798
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0273 0.2957 0.3655
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0082 0.006
Echinococcus multilocularis proteasome subunit alpha type 2 0.0112 0.1129 0.11
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0019 0.0077 0.0095
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0037 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0371 0.0456
Echinococcus granulosus geminin 0.0168 0.1767 0.174
Brugia malayi sulfakinin receptor protein 0.0075 0.072 0.0848
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0363
Mycobacterium leprae Probable lipase LipE 0.0036 0.0271 0.0204
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Echinococcus granulosus NCK adaptor protein 0.0015 0.0034 0.0002
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0127 0.0111
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.038 0.416 0.4141
Toxoplasma gondii heat shock protein hslv, putative 0.0112 0.1129 0.1737
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0112 0.1129 0.1396
Brugia malayi Dopamine receptor protein 2 0.0075 0.072 0.0848
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0398 0.0447
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0209 0.0259
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0112 0.1129 0.1351
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.038 0.416 0.5093
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0371 0.0417
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0273 0.2957 0.2934
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0102 0.1017 0.1255
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0045 0.0012
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0112 0.1129 0.1737
Brugia malayi nuclear hormone receptor family member odr-7 0.0179 0.1893 0.2298
Toxoplasma gondii proteasome beta subunit 0.0112 0.1129 0.1737
Echinococcus granulosus cpg binding protein 0.003 0.0208 0.0176
Echinococcus multilocularis NCK adaptor protein 0.0015 0.0034 0.0002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.038 0.416 0.4141
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0047 0.0404 0.0372
Echinococcus multilocularis transcription factor btf3 0.0035 0.0259 0.0228
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Loa Loa (eye worm) norepinephrine transporter 0.024 0.2577 0.3145
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0441 0.4854 0.7706
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0279 0.0247
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0075 0.072 0.069
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0112 0.1129 0.1687
Echinococcus granulosus proteasome prosome macropain 0.0568 0.6285 0.6273
Echinococcus multilocularis serotonin receptor 0.0196 0.2085 0.2059
Echinococcus multilocularis proteasome subunit beta type 7 0.0112 0.1129 0.11
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0112 0.1129 0.1353
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.024 0.2577 0.3145
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0075 0.072 0.069
Schistosoma mansoni adenoreceptor 0.0075 0.072 0.089
Leishmania major proteasome beta 5 subunit, putative 0.0568 0.6285 0.773
Onchocerca volvulus 0.0075 0.072 0.0794
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0209 0.0259
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.019 0.0192
Echinococcus multilocularis g protein coupled receptor 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis tyrosine protein kinase Abl 0.0019 0.0077 0.0044
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Echinococcus granulosus neuropeptide receptor 0.0075 0.072 0.069
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.3828
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0254 0.0311
Loa Loa (eye worm) steroid hormone receptor 0.038 0.416 0.5102
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.0281 0.0305
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.038 0.416 0.5102
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0127 0.0153
Schistosoma mansoni coup transcription factor 0.038 0.416 0.5145
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0026 0.0158 0.0125
Leishmania major C-8 sterol isomerase-like protein 0.0731 0.8121 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.0809 0.0779
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0026 0.0158 0.0181
Brugia malayi proteasome subunit beta type 3 0.0112 0.1129 0.1353
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0075 0.072 0.069
Echinococcus multilocularis g-protein coupled receptor 0.0075 0.072 0.069
Onchocerca volvulus 0.0065 0.0607 0.0652
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0112 0.1129 0.1351
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.072 0.089
Brugia malayi Furin-like cysteine rich region family protein 0.0298 0.3234 0.3957
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0102 0.1017 0.1255
Echinococcus granulosus Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0045 0.0055
Leishmania major proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0112 0.1129 0.1737
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.072 0.069
Echinococcus granulosus g protein coupled receptor 0.0075 0.072 0.069
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Entamoeba histolytica Ran family GTPase 0.0021 0.0103 0.0033
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0453
Brugia malayi ecdysone receptor 0.0179 0.1893 0.2298
Brugia malayi follicle stimulating hormone receptor 0.0075 0.072 0.0848
Onchocerca volvulus 0.0036 0.0271 0.0233
Echinococcus granulosus tyrosine protein kinase Blk 0.004 0.0321 0.029
Brugia malayi hypothetical protein 0.0026 0.0162 0.0158
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Echinococcus multilocularis phospholipase D 0.009 0.0886 0.0856
Giardia lamblia 20S proteasome alpha subunit 6 0.0112 0.1129 0.1659
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0025 0.0146 0.0162
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Treponema pallidum sodium- and chloride- dependent transporter 0.024 0.2577 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0271 0.0363
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) TYRA-2 protein 0.0075 0.072 0.0848
Loa Loa (eye worm) hypothetical protein 0.003 0.0209 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0568 0.6285 1
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0019 0.0085 0.006
Brugia malayi Fli-1 protein 0.0218 0.2331 0.2841
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0112 0.1129 0.1396
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0102 0.1017 0.0988
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0045 0.001
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0259 0.0318
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Schistosoma mansoni hypothetical protein 0.0125 0.1278 0.1581
Echinococcus granulosus fmrfamide receptor 0.0075 0.072 0.069
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0045 0.0013
Schistosoma mansoni hypothetical protein 0.0727 0.8086 1
Onchocerca volvulus Notchless protein homolog 0.0112 0.1129 0.1304
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0082 0.0102
Brugia malayi hypothetical protein 0.0179 0.1893 0.2298
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0112 0.1129 1
Loa Loa (eye worm) doublecortin family protein 0.002 0.0089 0.0067
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Schistosoma mansoni Tr4/Tr2 (homologue) 0.038 0.416 0.5145
Echinococcus granulosus phospholipase D1 0.0102 0.102 0.0991
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0037 0.0003
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0271 0.0363
Schistosoma mansoni tyrosine kinase 0.0019 0.0077 0.0095
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0259 0.0344
Echinococcus multilocularis 0.0092 0.0902 0.0873
Echinococcus multilocularis serotonin receptor 0.0196 0.2085 0.2059
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0082 0.0102
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0082 0.005
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0102 0.1017 0.1419
Echinococcus multilocularis proteasome subunit alpha type 6 0.0112 0.1129 0.11
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Echinococcus granulosus proteasome subunit beta type 6 0.0112 0.1129 0.11
Trypanosoma brucei cardiolipin synthetase, putative 0.0036 0.027 0.0288
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0045 0.0012
Loa Loa (eye worm) hypothetical protein 0.0028 0.0187 0.0189
Trichomonas vaginalis WD repeat domain, putative 0.0727 0.8086 1
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0112 0.1129 0.11
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Brugia malayi nuclear receptor RXR 0.0179 0.1893 0.2298
Loa Loa (eye worm) melatonin receptor type 1A 0.0075 0.072 0.0848
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0112 0.1129 0.1687
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0328 0.0405
Trypanosoma brucei Emopamil binding protein, putative 0.0273 0.2951 0.3605
Echinococcus granulosus tyrosine protein kinase Lyn 0.0047 0.0404 0.0372
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Onchocerca volvulus 0.0179 0.1893 0.2259
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0025 0.0146 0.0162
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Schistosoma mansoni ran 0.0021 0.0103 0.0127
Loa Loa (eye worm) TK/EGFR protein kinase 0.0298 0.3234 0.3957
Echinococcus multilocularis peroxidasin 0.0026 0.0162 0.013
Echinococcus granulosus tyrosine protein kinase Src42A 0.0047 0.0404 0.0372
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0271 0.0293
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0568 0.6285 0.773
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0268 0.0328
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0271 0.0335
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0273 0.2957 0.3657
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Echinococcus multilocularis phospholipase D1 0.0102 0.102 0.0991
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0568 0.6285 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.038 0.416 0.5102
Brugia malayi Proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0089 0.0056
Echinococcus multilocularis fmrfamide receptor 0.0075 0.072 0.069
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.072 0.069
Trypanosoma cruzi polyprenyl synthase, putative 0.0026 0.0158 0.015
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0082 0.005
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0271 0.0239
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-25 0.038 0.416 0.5102
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0045 0.001
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0273 0.2957 0.4667
Giardia lamblia Proteasome subunit beta type 1 0.0441 0.4854 0.7684
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0371 0.0456
Brugia malayi neuropeptide F receptor 0.0075 0.072 0.0848
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0112 0.1129 0.1351
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0019 0.0077 0.0044
Loa Loa (eye worm) TK protein kinase 0.004 0.0321 0.0355
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0201 0.2135 0.211
Giardia lamblia Proteasome subunit beta type 2 0.0273 0.2957 0.4617
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0025 0.0146 0.0162
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.072 0.069
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0273 0.2957 0.3613
Schistosoma mansoni tyrosine kinase 0.0047 0.0404 0.0499
Echinococcus multilocularis g protein coupled receptor 0.0075 0.072 0.069
Toxoplasma gondii hypothetical protein 0.0041 0.0328 0.0453
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Echinococcus multilocularis RUN 0.002 0.0089 0.0056
Schistosoma mansoni glutathione synthetase 0.0026 0.0158 0.0195
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Brugia malayi ABC transporter family protein 0.0021 0.0104 0.0086
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0328 0.0405
Schistosoma mansoni tyrosine kinase 0.0047 0.0404 0.0499
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0219 0.0229
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0089 0.007
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.072 0.069
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0025 0.0146 0.0135
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.072 0.089
Toxoplasma gondii ABC1 family protein 0.0036 0.0271 0.0363
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0112 0.1129 0.1687
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0026 0.0158 0.0181
Schistosoma mansoni alpha-1 adrenergic receptor 0.0075 0.072 0.089
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0037 0.0045
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0271 0.0239
Trichomonas vaginalis abcb9, putative 0.0021 0.0104 0.0125
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0026 0.0158 0.0153
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0271 0.0363
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus multilocularis somatostatin receptor 0.0075 0.072 0.069
Brugia malayi Nuclear hormone receptor family member nhr-31 0.038 0.416 0.5102
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Leishmania major C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Trichomonas vaginalis esterase, putative 0.0036 0.0271 0.0332
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.0104 0.0035
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0271 0.0363
Trypanosoma brucei cardiolipin synthetase 0.0036 0.027 0.0288
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Echinococcus multilocularis epidermal growth factor receptor 0.0161 0.1687 0.166
Brugia malayi nuclear hormone receptor family member nhr-6 0.0179 0.1893 0.2298
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0102 0.1017 0.1213
Plasmodium vivax proteasome subunit beta type-1, putative 0.0441 0.4854 0.7706
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Echinococcus granulosus G protein coupled receptor 139 0.0075 0.072 0.069
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0075 0.072 0.0794
Brugia malayi Protein K4 0.0016 0.0052 0.0022
Echinococcus granulosus hypothetical protein 0.076 0.8453 0.8448
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0187 0.0186
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0441 0.4854 0.5959
Brugia malayi Pre-SET motif family protein 0.0207 0.2207 0.2687
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0209 0.0259
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0112 0.1129 0.1396
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0679 0.0649
Schistosoma mansoni Lamin B receptor (ERG24) 0.0047 0.0398 0.0492
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0162 0.0158
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0082 0.005
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0219 0.0229
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.1278 0.125
Echinococcus multilocularis c src tyrosine kinase 0.0019 0.0077 0.0044
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0162 0.0096
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0026 0.0158 0.0019
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Toxoplasma gondii proteasome subunit alpha1, putative 0.0112 0.1129 0.1737
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Brugia malayi G protein-coupled receptor F59B2.13 0.0075 0.072 0.0848
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0453
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0271 0.0363
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0363
Echinococcus granulosus peptide allatostatin:somatostatin 0.0075 0.072 0.069
Onchocerca volvulus 0.0026 0.0162 0.0096
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0075 0.072 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.0169
Schistosoma mansoni multidrug resistance protein 0.0021 0.0104 0.0129
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0025 0.0146 0.0162
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0082
Loa Loa (eye worm) hypothetical protein 0.0081 0.0783 0.0926
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0025 0.0146 0.0162
Echinococcus multilocularis conserved hypothetical protein 0.0685 0.7601 0.7593
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0047 0.0404 0.0372
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0179 0.1893 0.2259
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0112 0.1129 0.1351
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0162 0.0158
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0097 0.0959 0.093
Echinococcus granulosus c src tyrosine kinase 0.0019 0.0077 0.0044
Echinococcus multilocularis expressed protein 0.037 0.4051 0.4031
Schistosoma mansoni hypothetical protein 0.0031 0.0219 0.0271
Brugia malayi orphan nuclear receptor NR2E1 0.0179 0.1893 0.2298
Schistosoma mansoni tyrosine kinase 0.0157 0.1645 0.2034
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi hypothetical protein 0.0121 0.1232 0.1481
Loa Loa (eye worm) hypothetical protein 0.0098 0.0978 0.1168
Echinococcus multilocularis fmrfamide receptor 0.0075 0.072 0.069
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0075 0.072 0.0848
Echinococcus multilocularis phospholipase d3 0.0019 0.0085 0.0053
Mycobacterium ulcerans hypothetical protein 0.0036 0.0271 0.0204
Echinococcus granulosus sex peptide receptor 0.0075 0.072 0.069
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0075 0.072 0.0848
Echinococcus granulosus proteasome subunit beta type 7 0.0112 0.1129 0.11
Brugia malayi Pre-SET motif family protein 0.003 0.0209 0.0216
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.072 0.089
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0082 0.0099
Trypanosoma cruzi cardiolipin synthetase, putative 0.0036 0.027 0.0288
Brugia malayi Tachykinin-like peptides receptor 99D 0.0075 0.072 0.0848
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi Nuclear hormone receptor-like 1 0.0201 0.2135 0.2598
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0104 0.0125
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.1278 0.125
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0112 0.1129 0.1737
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0219 0.0229
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0112 0.1129 0.1353
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0026 0.0158 0.0153
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0328 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-49 0.038 0.416 0.5102
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0259 0.0344
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0102 0.1017 0.1558
Echinococcus granulosus tyrosine kinase 0.004 0.0321 0.029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.072 0.069
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0112 0.1129 0.1396
Echinococcus multilocularis serotonin transporter 0.024 0.2577 0.2553
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0025 0.0146 0.0162
Schistosoma mansoni hypothetical protein 0.0168 0.1767 0.2185
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0179 0.1893 0.2259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Schistosoma mansoni thyroid hormone receptor 0.0505 0.5571 0.6889
Brugia malayi Nuclear hormone receptor-like 1 0.0201 0.2135 0.2598
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Brugia malayi protein-tyrosine kinase 0.004 0.0321 0.0355
Brugia malayi Will die slowly protein 0.0727 0.8086 0.9957
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus neuropeptide s receptor 0.0532 0.5876 0.5862
Brugia malayi 20S proteasome alpha5 subunit 0.0112 0.1129 0.1353
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0328 0.0296
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0731 0.8121 1
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0026 0.0158 0.015
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0269 0.0287
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0112 0.1129 0.1353
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0101 0.0069
Loa Loa (eye worm) hypothetical protein 0.0066 0.0618 0.0722
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0112 0.1129 0.1396
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0244 0.0257
Brugia malayi Serotonin receptor 0.0532 0.5876 0.7224
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0271 0.0293
Brugia malayi Nuclear hormone receptor family member nhr-41 0.038 0.416 0.5102
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0254 0.0311
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Echinococcus multilocularis proteasome (prosome, macropain) 0.0568 0.6285 0.6273
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Echinococcus granulosus subfamily T1A non peptidase ue 0.0112 0.1129 0.11
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) nuclear receptor NHR-67 0.0179 0.1893 0.2298
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0112 0.1129 0.11
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0259 0.0276
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0363
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0112 0.1129 0.1396
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0112 0.1129 0.1687
Echinococcus multilocularis snurportin 1 0.0302 0.3277 0.3255
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0277 0.2997 0.2974
Entamoeba histolytica P-glycoprotein-5 0.0021 0.0104 0.0035
Echinococcus multilocularis FTZ F1 alpha 0.038 0.416 0.4141
Trypanosoma cruzi cardiolipin synthetase, putative 0.0036 0.027 0.0288
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.098
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0179 0.1893 0.2298
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0398 0.0447
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0201 0.2135 0.211
Echinococcus granulosus ecdysone induced protein 78C 0.038 0.416 0.4141
Brugia malayi cytochrome P450 0.0025 0.0146 0.0138
Trypanosoma brucei proteasome beta 6 subunit 0.0441 0.4854 0.5959
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0102 0.1017 0.0988
Echinococcus granulosus tm gpcr rhodopsin 0.0589 0.652 0.6509
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0016 0.0052 0.0012
Entamoeba histolytica protein kinase, putative 0.0033 0.0237 0.0249
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0112 0.1129 0.11
Brugia malayi beta-lactamase family protein 0.0036 0.0271 0.0293
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Leishmania major proteasome beta 2 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0201 0.2135 0.2641
Entamoeba histolytica phospholipase D, putative 0.0102 0.102 0.1512
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0112 0.1129 0.11
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Brugia malayi hypothetical protein 0.0065 0.0607 0.0708
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0112 0.1129 0.1353
Schistosoma mansoni biogenic amine (5HT) receptor 0.0196 0.2085 0.2578
Brugia malayi nuclear hormone receptor 0.0179 0.1893 0.2298
Brugia malayi Doublecortin family protein 0.002 0.0089 0.0067
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0015 0.0034 0.0042
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0112 0.1129 0.1687
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0259 0.0276
Echinococcus multilocularis 0.0025 0.0146 0.0114
Leishmania major cytochrome p450-like protein 0.0033 0.0244 0.0257
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0089 0.0056
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0112 0.1129 0.1737
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0271 0.0204
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0162 0.0096
Schistosoma mansoni hypothetical protein 0.002 0.0089 0.011
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0237 0.0205
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.072 0.089
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0082 0.005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.038 0.416 0.5102
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.1189 0.1161
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.038 0.416 0.5102
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0244 0.0259
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0047 0.0404 0.0372
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0103 0.007
Echinococcus multilocularis epidermal growth factor receptor 0.0298 0.3234 0.3212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Brugia malayi Proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0085
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0273 0.2957 0.3613
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0089 0.0056
Echinococcus granulosus nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0161 0.1687 0.166
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0104 0.0125
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.072 0.069
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0026 0.0158 0.0181
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.1189 0.1161
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0025 0.0146 0.0162
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0112 0.1129 0.1737
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Echinococcus granulosus thyroid hormone receptor alpha 0.0179 0.1893 0.1866
Trypanosoma brucei C-8 sterol isomerase, putative 0.0731 0.8121 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Schistosoma mansoni importin beta-1 0.0028 0.0187 0.0231
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0026 0.0158 0.015
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0162 0.0158
Giardia lamblia 20S proteasome alpha subunit 3 0.0112 0.1129 0.1659
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0112 0.1129 0.11
Brugia malayi hypothetical protein 0.002 0.0089 0.0067
Loa Loa (eye worm) hypothetical protein 0.0486 0.536 0.6586
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0679 0.0798
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Schistosoma mansoni hypothetical protein 0.0168 0.1767 0.2185
Onchocerca volvulus Peroxidase homolog 0.0026 0.0162 0.0096
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0019 0.0077 0.0044
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.024 0.2577 0.3187
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Echinococcus multilocularis g protein coupled receptor 0.0075 0.072 0.069
Schistosoma mansoni tyrosine kinase 0.0157 0.1645 0.2034
Schistosoma mansoni steroid hormone receptor ad4bp 0.038 0.416 0.5145
Schistosoma mansoni hypothetical protein 0.0036 0.0271 0.0335
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Brugia malayi hypothetical protein 0.0179 0.1893 0.2298
Loa Loa (eye worm) hypothetical protein 0.0086 0.0836 0.0991
Echinococcus granulosus dro:myosuppressin receptor 0.0075 0.072 0.069
Schistosoma mansoni rab6-interacting 0.002 0.0089 0.011
Trichomonas vaginalis ran, putative 0.0021 0.0103 0.0124
Onchocerca volvulus 0.0273 0.2951 0.3581
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.019 0.0158
Brugia malayi conserved hypotetical protein 0.0179 0.1893 0.2298
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0271 0.0363
Schistosoma mansoni biogenic amine receptor 0.0075 0.072 0.089
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Leishmania major proteasome beta-1 subunit, putative 0.0112 0.1129 0.1351
Brugia malayi RNA, U transporter 1 0.008 0.0776 0.0917
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Trypanosoma cruzi Emopamil binding protein, putative 0.0273 0.2951 0.3605
Brugia malayi hypothetical protein 0.0036 0.0271 0.0293
Trypanosoma brucei C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0441 0.4854 0.5959
Echinococcus multilocularis jun protein 0.0083 0.0809 0.0779
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0082 0.005
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Leishmania major basic transcription factor 3a, putative 0.0035 0.0259 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0242 0.0296
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0897 1 1
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0104 0.0035
Brugia malayi Cytochrome P450 family protein 0.0033 0.0244 0.0259
Toxoplasma gondii peptidase, T1 family protein 0.0112 0.1129 0.1737
Echinococcus granulosus alpha 1A adrenergic receptor 0.0075 0.072 0.069
Brugia malayi proteasome subunit beta type 1 0.0441 0.4854 0.596
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0047 0.0404 0.0372
Loa Loa (eye worm) serotonin transporter b 0.024 0.2577 0.3145
Echinococcus granulosus jun protein 0.0083 0.0809 0.0779
Schistosoma mansoni cytochrome P450 0.0025 0.0146 0.018
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0112 0.1129 0.1737
Onchocerca volvulus 0.0026 0.0162 0.0096
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0075 0.072 0.0848
Echinococcus granulosus tachykinin peptides receptor 99D 0.0075 0.072 0.069
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.038 0.416 0.5102
Echinococcus granulosus nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.0169
Echinococcus granulosus serotonin receptor 0.0075 0.072 0.069
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0112 0.1129 0.1396
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0025 0.0146 0.0162
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.072 0.069
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0112 0.1129 0.1396
Brugia malayi steroid hormone receptor 0.038 0.416 0.5102
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0025 0.0146 0.0162
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0112 0.1129 0.1659
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0037 0.0004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0086 0.0836 0.1215
Loa Loa (eye worm) fli-1 protein 0.0218 0.2331 0.2841
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0025 0.0146 0.0162
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0085
Trypanosoma brucei proteasome alpha 7 subunit 0.0112 0.1129 0.1351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0169 0.0205
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0112 0.1129 0.1351
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Loa Loa (eye worm) SRC-1 0.0047 0.0404 0.0457
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) hypothetical protein 0.0201 0.2135 0.2598
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0104 0.0086
Brugia malayi bZIP transcription factor family protein 0.0083 0.0809 0.0958
Echinococcus granulosus lamin b receptor 0.0047 0.0398 0.0367
Trichomonas vaginalis set domain proteins, putative 0.0236 0.2529 0.3125
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0112 0.1129 0.1687
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0104 0.0125
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0201 0.2135 0.2641
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0026 0.0158 0.0121
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0075 0.072 0.0848
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0242 0.0317
Schistosoma mansoni adapter molecule crk 0.0015 0.0034 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0244 0.016
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0179 0.1893 0.1866
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0731 0.8121 1
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0112 0.1129 0.1687
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0101 0.0069
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.0125
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.072 0.0848
Mycobacterium ulcerans lipase LipD 0.0036 0.0271 0.0204
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0047 0.0404 0.0372
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0127 0.0153
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0441 0.4854 0.7692
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0112 0.1129 0.1737
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0371 0.0466
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0082 0.006
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0067
Leishmania major GTP-binding protein, putative 0.0021 0.0103 0.0082
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0112 0.1129 0.1737
Brugia malayi Nuclear hormone receptor E75 0.0179 0.1893 0.2298
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0328 0.0405
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0025 0.0146 0.0162
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0328 0.0296
Brugia malayi hypothetical protein 0.0041 0.0328 0.0363
Echinococcus granulosus neuropeptide FF receptor 2 0.0075 0.072 0.069
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.038 0.416 0.4141
Loa Loa (eye worm) beta-lactamase 0.0036 0.0271 0.0293
Schistosoma mansoni amine GPCR 0.0075 0.072 0.089
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0082 0.005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0052 0.0022
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0328 0.0405
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0112 0.1129 0.1396
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0104 0.0072
Echinococcus multilocularis insulin receptor 0.0097 0.0959 0.093
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0332
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0321 0.029
Giardia lamblia 20S proteasome alpha subunit 2 0.0112 0.1129 0.1659
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Schistosoma mansoni peroxidasin 0.0026 0.0162 0.0201
Echinococcus granulosus serotonin transporter 0.024 0.2577 0.2553
Loa Loa (eye worm) hypothetical protein 0.0019 0.0085 0.0063
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0112 0.1129 0.1351
Echinococcus granulosus expressed protein 0.037 0.4051 0.4031
Schistosoma mansoni nuclear hormone receptor 0.038 0.416 0.5145
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0082 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0139 0.0169
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus granulosus 7tm_1 domain containing protein 0.0075 0.072 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0298 0.0365
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0273 0.2951 0.3605
Brugia malayi Blistered cuticle protein 3 0.0026 0.0162 0.0158
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0025 0.0146 0.0162
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.0195
Schistosoma mansoni peroxidasin 0.0026 0.0162 0.0201
Schistosoma mansoni nuclear receptor nhr-48 0.0179 0.1893 0.234
Echinococcus granulosus snurportin 1 0.0302 0.3277 0.3255
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0082 0.006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.072 0.089
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0271 0.0363
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0016 0.0052 0.0012
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0441 0.4854 0.4837
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0104 0.0072
Leishmania major proteasome alpha 7 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis G-protein coupled receptor, putative 0.0075 0.072 0.069
Echinococcus granulosus g protein coupled receptor 0.0075 0.072 0.069
Brugia malayi Melatonin receptor type 1A 0.0075 0.072 0.0848
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0082 0.0102
Trypanosoma cruzi C-14 sterol reductase, putative 0.0047 0.0398 0.0447
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0075 0.072 0.069
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.2207 0.2687
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.072 0.069
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0112 0.1129 0.1353
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Echinococcus multilocularis lamin b receptor 0.0047 0.0398 0.0367
Onchocerca volvulus Neuropeptide F receptor homolog 0.0075 0.072 0.0794
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0102 0.1017 0.1558
Onchocerca volvulus 0.024 0.2577 0.3115
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Onchocerca volvulus 0.0021 0.0104 0.0024
Plasmodium vivax proteasome subunit beta type-6, putative 0.0112 0.1129 0.1737
Brugia malayi Nuclear hormone receptor-like 1 0.038 0.416 0.5102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.014 0.0169
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0112 0.1129 0.1393
Entamoeba histolytica hypothetical protein 0.0035 0.0259 0.0285
Onchocerca volvulus 0.0041 0.0328 0.0303
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Plasmodium vivax proteasome subunit beta type-4, putative 0.0112 0.1129 0.1737
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0112 0.1129 0.1737
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0162 0.0096
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0112 0.1129 0.1396
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0112 0.1129 0.1737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0037 0.0042
Schistosoma mansoni growth hormone secretagogue receptor 0.0075 0.072 0.089
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0112 0.1129 0.1353
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0271 0.0204
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0112 0.1129 0.1737
Echinococcus granulosus peroxidasin 0.0026 0.0162 0.013
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0045 0.0012
Echinococcus granulosus cytochrome P450 2K1 0.0025 0.0146 0.0114
Schistosoma mansoni retinoic acid receptor RXR 0.0478 0.5265 0.6511
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0205 0.0251
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.072 0.069
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1869 0.2308
Brugia malayi G-protein coupled receptor 0.0075 0.072 0.0848
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0319 0.0395
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.038 0.416 0.4141
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0067
Brugia malayi Serotonin receptor 0.0075 0.072 0.0848
Schistosoma mansoni cpg binding protein 0.003 0.0208 0.0257
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0271 0.0335
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0259 0.0285
Echinococcus granulosus dnaJ subfamily B 0.0406 0.4451 0.4433
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Giardia lamblia 20S proteasome alpha subunit 7 0.0112 0.1129 0.1659
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0279 0.0247
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0082
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0075 0.072 0.089
Schistosoma mansoni tyrosine kinase 0.0097 0.0959 0.1187
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0112 0.1129 0.11
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0179 0.1893 0.2298
Toxoplasma gondii hypothetical protein 0.0041 0.0328 0.0453
Trypanosoma cruzi polyprenyl synthase, putative 0.0026 0.0158 0.015
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.004 0.0321 0.029
Echinococcus granulosus neuropeptide receptor A26 0.0532 0.5876 0.5862
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.072 0.0848
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0104 0.0072
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0112 0.1129 0.11
Brugia malayi Steroid receptor seven-up type 2 0.038 0.416 0.5102
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0025 0.0146 0.0162
Brugia malayi Phospholipase D. Active site motif family protein 0.0019 0.0085 0.0063
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0075 0.072 0.0848
Schistosoma mansoni retinoid-x-receptor (RXR) 0.038 0.416 0.5145
Echinococcus granulosus orexin receptor type 2 0.0075 0.072 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0169 0.0205
Echinococcus multilocularis protein will die slowly 0.0727 0.8086 0.808
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0075 0.072 0.0848
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0082 0.006
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0075 0.072 0.089
Loa Loa (eye worm) PAS-3 protein 0.0112 0.1129 0.1353
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0075 0.072 0.069
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0112 0.1129 0.1687
Schistosoma mansoni gabp alpha 0.0072 0.0679 0.084
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Brugia malayi PXA domain containing protein 0.0023 0.0133 0.0121
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.0104 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Onchocerca volvulus 0.0075 0.072 0.0794
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0271 0.0239
Leishmania major proteasome beta 2 subunit, putative 0.0273 0.2957 0.3613
Plasmodium falciparum proteasome subunit beta type-4 0.0112 0.1129 0.1737
Leishmania major proteasome alpha 1 subunit, putative 0.0112 0.1129 0.1351
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0082 0.0102
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0209 0.0264
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0075 0.072 0.069
Leishmania major p-glycoprotein 0.0021 0.0104 0.0083
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0271 0.0204
Brugia malayi hypothetical protein 0.0016 0.0052 0.0022
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.3277 0.401
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0106 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0082 0.0099
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0404 0.0372
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0075 0.072 0.069
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0077 0.005
Echinococcus multilocularis dro:myosuppressin receptor 0.0075 0.072 0.069
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0026 0.0158 0.0019
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0179 0.1893 0.234
Onchocerca volvulus 0.0075 0.072 0.0794
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0104 0.0125
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0166 0.0201
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0047 0.0404 0.0372
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0104 0.0125
Echinococcus granulosus g-protein coupled receptor 0.0075 0.072 0.069
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0045 0.001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0293
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0244 0.0257
Echinococcus granulosus neuropeptide receptor 0.0075 0.072 0.069
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0075 0.072 0.089
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0036 0.027 0.036
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0082 0.0102
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0026 0.0158 0.0125
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0478 0.5265 0.5249
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.2762 0.3373
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0104 0.0072
Schistosoma mansoni transcription factor btf3 0.0035 0.0259 0.0321
Echinococcus multilocularis ecdysone induced protein 78C 0.038 0.416 0.4141
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0025 0.0146 0.0135
Schistosoma mansoni lipoxygenase 0.0082 0.0792 0.0979
Onchocerca volvulus 0.0075 0.072 0.0794
Loa Loa (eye worm) TK protein kinase 0.0033 0.0237 0.0251
Onchocerca volvulus Protein ultraspiracle homolog 0.038 0.416 0.5093
Echinococcus granulosus microtubule associated protein 2 0.0685 0.7601 0.7593
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0328 0.0453
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.072 0.069
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0075 0.072 0.0848
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0075 0.072 0.0848
Entamoeba histolytica hypothetical protein 0.0036 0.0271 0.0304
Schistosoma mansoni microtubule-associated protein tau 0.0685 0.7601 0.94
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.038 0.416 0.4141
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0102 0.1017 0.1558
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.072 0.089
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0158
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0112 0.1129 0.1737
Schistosoma mansoni ets-related 0.0218 0.2331 0.2883
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.038 0.416 0.4141
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0273 0.2957 0.2934
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0219 0.0187
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0112 0.1129 0.1393
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.049 0.0713
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0047 0.0404 0.0372
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.1767 0.2102
Loa Loa (eye worm) hypothetical protein 0.0075 0.072 0.0848
Echinococcus granulosus tyrosine protein kinase Src64B 0.0047 0.0404 0.0372
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0112 0.1129 0.1687
Schistosoma mansoni loxhd1 0.002 0.0089 0.011
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0112 0.1129 0.1687
Entamoeba histolytica P-glycoprotein-1 0.0021 0.0104 0.0035
Brugia malayi Ets-domain containing protein 0.0072 0.0679 0.0798
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Brugia malayi G protein-coupled receptor 0.0075 0.072 0.0848
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Brugia malayi Polyprenyl synthetase family protein 0.0026 0.0158 0.0153
Onchocerca volvulus 0.0028 0.019 0.013
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.2762 0.3413
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0026 0.0158 0.0125
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0026 0.0158 0.0125
Brugia malayi beta-lactamase family protein 0.0036 0.0271 0.0293
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0371 0.0414
Schistosoma mansoni cpg binding protein 0.003 0.0208 0.0257
Leishmania major cardiolipin synthetase, putative 0.0016 0.0052 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0025 0.0146 0.0162
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0104 0.0125
Plasmodium falciparum proteasome subunit beta type-5 0.0568 0.6285 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0589 0.652 0.6509
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0082 0.005
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0075 0.072 0.089
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.072 0.089
Brugia malayi PXA domain containing protein 0.0023 0.0133 0.0121
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.038 0.416 0.5102
Loa Loa (eye worm) hypothetical protein 0.0179 0.1893 0.2298
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0371 0.0414
Schistosoma mansoni lipoxygenase 0.0117 0.1189 0.1471
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0045 0.0013
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0363
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0104 0.0095
Leishmania major proteasome beta 3 subunit, putative 0.0112 0.1129 0.1351
Loa Loa (eye worm) proteasome subunit beta type 1 0.0441 0.4854 0.596
Schistosoma mansoni biogenic amine receptor 0.0075 0.072 0.089
Echinococcus granulosus Proteasome subunit alpha beta 0.0112 0.1129 0.11
Onchocerca volvulus 0.0075 0.072 0.0794
Leishmania major proteasome alpha 2 subunit, putative 0.0112 0.1129 0.1351
Echinococcus granulosus protein will die slowly 0.0727 0.8086 0.808
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0082 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0259 0.0318
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0112 0.1129 0.1737
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0127 0.0153
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0112 0.1129 0.1396
Loa Loa (eye worm) DR-78 0.0179 0.1893 0.2298
Echinococcus multilocularis neuropeptide receptor 0.0075 0.072 0.069
Brugia malayi nuclear receptor NHR-88 0.0179 0.1893 0.2298
Schistosoma mansoni biogenic amine receptor 0.0075 0.072 0.089
Giardia lamblia 20S proteasome alpha subunit 4 0.0112 0.1129 0.1659
Schistosoma mansoni hypothetical protein 0.0075 0.072 0.089
Schistosoma mansoni sodium/chloride dependent transporter 0.024 0.2577 0.3187
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0112 0.1129 0.1353
Leishmania major importin beta-1 subunit, putative 0.0023 0.0127 0.0111
Schistosoma mansoni cpg binding protein 0.0028 0.019 0.0234
Echinococcus granulosus nuclear receptor nhr 48 0.0179 0.1893 0.1866
Schistosoma mansoni multidrug resistance protein 0.0021 0.0104 0.0129
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0112 0.1129 0.1351
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0441 0.4854 0.7706
Plasmodium vivax importin-beta 2, putative 0.0028 0.0187 0.0228
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.2445 0.3847
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0133 0.0121
Brugia malayi hypothetical protein 0.0075 0.072 0.0848
Schistosoma mansoni growth factor receptor-bound protein 0.0015 0.0034 0.0042
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0441 0.4854 0.5959
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0082 0.006
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1767 0.2182
Echinococcus granulosus proteasome subunit beta t family 0.0112 0.1129 0.11

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) = 3226 Cardiotoxicity by a neonatal rat heart myocyte assay ChEMBL. 8648600
IC50 (functional) = 2.9 nM Inhibitory activity against sensitive L1210 cell lines ChEMBL. 8648600
IC50 (functional) = 2.9 nM Inhibitory activity against sensitive L1210 cell lines ChEMBL. 8648600
IC50 (functional) = 6.8 nM Inhibitory activity against resistant murine leukemia L1210 cell lines. ChEMBL. 8648600
IC50 (functional) = 6.8 nM Inhibitory activity against resistant murine leukemia L1210 cell lines. ChEMBL. 8648600
IC50 (functional) = 29 nM Inhibitory activity against AUC375 cell line ChEMBL. 8648600
IC50 (functional) = 69 nM An average for IC50 values in the two solid tumor cell lines and sensitive L1210 leukemia cell line. ChEMBL. 8648600
IC50 (functional) = 103 nM An average for IC50 values in the two solid tumor cell lines. ChEMBL. 8648600
IC50 (functional) = 176 nM Inhibitory activity against OVCAR-3 cell line ChEMBL. 8648600
IC50 (functional) = 176 nM Inhibitory activity against OVCAR-3 cell line ChEMBL. 8648600
Toxicity ratio (functional) = 47 Toxicity ratio determined by the quotient of IC50 values in the mycocytes divided by the average value in the three tumor lines. ChEMBL. 8648600

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 8648600
Homo sapiens ChEMBL23 8648600

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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