Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0399 | 0.0399 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.061 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0049 | 0.0399 | 0.0399 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0049 | 0.0399 | 0.0399 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0177 | 0.2579 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0399 | 0.0399 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.061 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | aldehyde reductase | 0.0433 | 0.6974 | 0.6974 |
Schistosoma mansoni | aldo-keto reductase | 0.061 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.061 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.061 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.061 | 1 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.061 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.061 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.061 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.061 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0397 | 0.0397 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.061 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0049 | 0.0399 | 0.0399 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0049 | 0.0399 | 0.0399 |
Entamoeba histolytica | aldose reductase, putative | 0.061 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.061 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0049 | 0.0399 | 0.0399 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.061 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Plasmodium vivax | aldehyde reductase, putative | 0.0177 | 0.2579 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0177 | 0.2579 | 0.2579 |
Echinococcus granulosus | aldo keto reductase | 0.061 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | oxidoreductase | 0.061 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.061 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.061 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.061 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.061 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0049 | 0.0399 | 0.0399 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0049 | 0.0399 | 0.0399 |
Entamoeba histolytica | aldose reductase, putative | 0.061 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0399 | 0.0399 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0397 | 0.0397 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0049 | 0.0399 | 0.0399 |
Onchocerca volvulus | 0.061 | 1 | 1 | |
Onchocerca volvulus | 0.061 | 1 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0049 | 0.0399 | 0.0399 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.061 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.061 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0049 | 0.0399 | 0.0399 |
Trypanosoma brucei | prostaglandin f synthase | 0.061 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0049 | 0.0399 | 0.0399 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0177 | 0.2579 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0397 | 0.0397 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.061 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.061 | 1 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0161 | 0.2309 | 0.2309 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0049 | 0.0399 | 0.0399 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.061 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0049 | 0.0399 | 0.0399 |
Schistosoma mansoni | aldo-keto reductase | 0.061 | 1 | 1 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0177 | 0.2579 | 0.2579 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.061 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.061 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0049 | 0.0399 | 0.0399 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0397 | 0.0397 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.061 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0397 | 0.0397 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0177 | 0.2579 | 0.2579 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.061 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.061 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.061 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.061 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | aldo keto reductase | 0.061 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0399 | 0.0399 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0177 | 0.2579 | 0.2579 |
Giardia lamblia | Aldose reductase | 0.061 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.061 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.061 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0049 | 0.0399 | 0.0399 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.061 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.2309 | 0.2309 |
Onchocerca volvulus | 0.061 | 1 | 1 | |
Onchocerca volvulus | 0.061 | 1 | 1 | |
Echinococcus granulosus | muscleblind protein | 0.0161 | 0.2309 | 0.2309 |
Brugia malayi | nuclear hormone receptor | 0.0049 | 0.0399 | 0.0399 |
Trypanosoma cruzi | aldo-keto reductase | 0.061 | 1 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0433 | 0.6974 | 0.5922 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Onchocerca volvulus | 0.061 | 1 | 1 | |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0049 | 0.0399 | 0.0399 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0161 | 0.2309 | 0.2309 |
Giardia lamblia | Aldose reductase | 0.061 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0399 | 0.0399 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0049 | 0.0399 | 0.0399 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0049 | 0.0399 | 0.0399 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0049 | 0.0399 | 0.0399 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0177 | 0.2579 | 0.2579 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0049 | 0.0399 | 0.0399 |
Schistosoma mansoni | potassium channel beta | 0.0177 | 0.2579 | 0.2579 |
Onchocerca volvulus | 0.0177 | 0.2579 | 0.2271 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0397 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.2309 | 0.2309 |
Entamoeba histolytica | aldose reductase, putative | 0.061 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0049 | 0.0399 | 0.0399 |
Toxoplasma gondii | aldose reductase, putative | 0.061 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.061 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0049 | 0.0399 | 0.0399 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0049 | 0.0399 | 0.0399 |
Onchocerca volvulus | 0.061 | 1 | 1 | |
Echinococcus granulosus | hypothetical protein | 0.061 | 1 | 1 |
Echinococcus granulosus | aldehyde reductase | 0.0433 | 0.6974 | 0.6974 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0049 | 0.0399 | 0.0399 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.061 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.061 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0399 | 0.0399 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0177 | 0.2579 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0049 | 0.0399 | 0.0399 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.0397 | 0.0397 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0049 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | oxidoreductase | 0.061 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | aldo keto reductase | 0.061 | 1 | 1 |
Brugia malayi | NADH-dependent xylose reductase | 0.0177 | 0.2579 | 0.2579 |
Echinococcus multilocularis | muscleblind protein | 0.0161 | 0.2309 | 0.2309 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.0397 | 0.0397 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0397 | 0.0397 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.061 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.061 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0049 | 0.0399 | 0.0399 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0049 | 0.0399 | 0.0399 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.061 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0049 | 0.0399 | 0.0399 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0049 | 0.0399 | 0.0399 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.