Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.7978 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.1149 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.1149 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0114 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0947 | 0.1287 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.1149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.3679 | 0.3972 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0435 | 0.0546 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.1149 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.1149 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.1149 | 0.5 |
Onchocerca volvulus | 0.0024 | 0.1149 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.4417 | 0.4769 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1149 | 0.124 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0435 | 0.0592 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0114 | 0.0123 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.1149 | 0.5 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0114 | 0.5 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.1149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1149 | 0.124 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.1149 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0947 | 0.1287 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.1149 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.1149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0114 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1149 | 0.124 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0947 | 0.1188 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0618 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0114 | 0.0123 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.1356 | 0.0234 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.1149 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.1149 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.3258 | 0.4427 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0106 | 0.0114 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0435 | 0.0592 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0114 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0114 | 0.0123 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.3258 | 0.4427 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0114 | 0.0123 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.1149 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.1149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.4087 | 0.4413 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.1149 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.736 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.9262 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.3667 | 0.2845 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0618 | 0.0774 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.736 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.1149 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.1149 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.