Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0023 | 0.1081 | 0.5 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0587 | 0.543 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0656 | 0.5 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1081 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.3894 | 0.3466 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1081 | 0.0455 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0656 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.3894 | 0.3466 |
Trichomonas vaginalis | ferritin, putative | 0.0008 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0587 | 0.543 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.3894 | 0.3154 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1081 | 0.5 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.1081 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.1081 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1081 | 0.0455 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 1 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.1081 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1081 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0008 | 0 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1081 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3894 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.1081 | 0.5 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.1081 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3894 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1081 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1081 | 0.0455 |
Brugia malayi | RNA binding protein | 0.0062 | 0.3894 | 0.3154 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3894 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3894 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 1 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.1081 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.1081 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.1081 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 1 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.1081 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.3894 | 0.3466 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3894 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1081 | 0.5 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.1081 | 0.5 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0656 | 0.6065 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.3894 | 0.3894 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0587 | 0.543 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.3894 | 0.3894 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.1081 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0587 | 0.543 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0656 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.1081 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.0656 | 0.6065 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.3894 | 0.3154 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.