Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0248 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0122 | 0.013 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.0288 | 0.039 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0097 | 0.1006 | 0.55 |
Onchocerca volvulus | 0.0038 | 0.0248 | 0.038 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0408 | 0.1209 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0248 | 0.0606 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0097 | 0.1006 | 0.2662 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0235 | 0.0557 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0029 | 0.0122 | 0.0354 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0122 | 0.0151 |
Echinococcus granulosus | uridine phosphorylase 1 | 0.0059 | 0.0518 | 0.0929 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.258 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.3363 |
Mycobacterium leprae | Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) | 0.0287 | 0.3444 | 1 |
Brugia malayi | dihydrofolate reductase family protein | 0.0045 | 0.0335 | 0.0972 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0122 | 0.0354 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0096 | 0.0986 | 0.0875 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0248 | 0.0963 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0248 | 0.0721 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0029 | 0.0122 | 0.0151 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0639 | 0.1683 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0029 | 0.0122 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0857 | 0.2898 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0056 | 0.0477 | 0.1069 |
Toxoplasma gondii | phosphorylase family protein | 0.0059 | 0.0518 | 0.258 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0029 | 0.0122 | 0.0207 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0029 | 0.0122 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0433 | 0.1301 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0209 | 0.0984 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0209 | 0.0204 |
Plasmodium falciparum | purine nucleoside phosphorylase | 0.0059 | 0.0518 | 0.258 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0458 | 0.1396 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0375 | 0.1082 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0248 | 0.0606 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0458 | 0.133 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0248 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.069 | 0.2269 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0248 | 0.038 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0073 | 0.069 | 0.3606 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0056 | 0.0477 | 0.0832 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0029 | 0.0122 | 0.0207 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0029 | 0.0122 | 0.0151 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.7784 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0248 | 0.0963 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.0623 | 0.2019 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0248 | 0.038 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0059 | 0.0518 | 0.1193 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0097 | 0.1006 | 0.2662 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0086 | 0.0857 | 0.1722 |
Treponema pallidum | pfs protein (pfs) | 0.0059 | 0.0518 | 0.5316 |
Echinococcus granulosus | inosine guanosine and xanthosine phosphorylase | 0.0228 | 0.268 | 0.5994 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.1006 | 0.3461 |
Brugia malayi | Dihydrofolate reductase | 0.0045 | 0.0335 | 0.0972 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.4483 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0269 | 0.0781 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0073 | 0.069 | 0.1835 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0073 | 0.069 | 0.3606 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0156 | 0.1758 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0038 | 0.024 | 0.0357 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0248 | 0.038 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0122 | 0.0354 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0038 | 0.024 | 0.0916 |
Onchocerca volvulus | 0.0111 | 0.1178 | 0.3178 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0235 | 0.0683 |
Entamoeba histolytica | hypothetical protein | 0.0059 | 0.0518 | 0.4483 |
Echinococcus multilocularis | thymidylate synthase | 0.0111 | 0.1178 | 0.1069 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0248 | 0.0963 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0038 | 0.024 | 0.0357 |
Schistosoma mansoni | dihydrofolate reductase | 0.0045 | 0.0335 | 0.0972 |
Schistosoma mansoni | uridine phosphorylase | 0.0059 | 0.0518 | 0.1505 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.0059 | 0.0518 | 0.258 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0111 | 0.1178 | 0.3178 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0029 | 0.0122 | 0.0207 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.0623 | 0.2019 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.4483 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0096 | 0.0986 | 0.2025 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0059 | 0.0518 | 0.1193 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0045 | 0.0335 | 0.0782 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.0288 | 0.0837 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.4483 |
Mycobacterium ulcerans | bifunctional Mta/Sah nucleosidase Mtn | 0.0059 | 0.0518 | 0.1193 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0029 | 0.0122 | 0.0151 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0246 | 0.291 | 0.8417 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0097 | 0.1006 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0097 | 0.1006 | 0.55 |
Echinococcus multilocularis | uridine phosphorylase 1 | 0.0059 | 0.0518 | 0.0401 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0097 | 0.1006 | 0.2922 |
Trypanosoma brucei | uridine phosphorylase | 0.0059 | 0.0518 | 0.258 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0038 | 0.024 | 0.0916 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0056 | 0.0477 | 0.0359 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0857 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0248 | 0.0526 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0248 | 0.0526 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0111 | 0.1178 | 0.3281 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0087 | 0.0254 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0248 | 0.0963 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0228 | 0.268 | 0.2589 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0857 | 0.2212 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.0986 | 0.2863 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0248 | 0.0526 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0209 | 0.0088 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0048 | 0.0375 | 0.0592 |
Onchocerca volvulus | 0.0047 | 0.0364 | 0.0728 | |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.069 | 0.2269 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0029 | 0.0122 | 0.0151 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0038 | 0.024 | 0.0357 |
Brugia malayi | MTAP | 0.0059 | 0.0518 | 0.1505 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0458 | 0.1396 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0059 | 0.0518 | 0.1327 |
Toxoplasma gondii | Purine nucleoside phosphorylase | 0.0059 | 0.0518 | 0.258 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.0059 | 0.0518 | 0.258 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0209 | 0.0984 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0269 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.069 | 0.2269 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0096 | 0.0986 | 0.0875 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0364 | 0.1056 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0857 | 1 |
Chlamydia trachomatis | AMP nucleosidase | 0.0059 | 0.0518 | 0.3517 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0364 | 0.0245 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.0623 | 0.2019 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0097 | 0.0998 | 0.0887 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0059 | 0.0518 | 0.1505 |
Giardia lamblia | Deoxynucleoside kinase | 0.04 | 0.4886 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0623 | 0.181 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0269 | 0.0781 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0131 | 0.1439 | 0.5092 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0156 | 0.1758 | 1 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.1193 |
Brugia malayi | AMP-binding enzyme family protein | 0.0097 | 0.1006 | 0.2922 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0097 | 0.0998 | 0.2899 |
Mycobacterium tuberculosis | Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase | 0.0059 | 0.0518 | 0.1327 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0248 | 0.038 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0857 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0131 | 0.1439 | 0.5092 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0364 | 0.1056 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0029 | 0.0122 | 0.0151 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0038 | 0.024 | 0.0278 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0248 | 0.0721 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0068 | 0.0623 | 0.0508 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0036 | 0.0211 | 0.0612 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0059 | 0.0518 | 0.1327 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0045 | 0.0327 | 0.095 |
Echinococcus multilocularis | expressed conserved protein | 0.0091 | 0.0923 | 0.0811 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0097 | 0.1006 | 0.2662 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0086 | 0.0857 | 0.4606 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0235 | 0.0683 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0033 | 0.0176 | 0.0128 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0122 | 0.0207 |
Leishmania major | nucleoside phosphorylase-like protein | 0.0059 | 0.0518 | 0.258 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0248 | 0.0721 |
Brugia malayi | hypothetical protein | 0.0053 | 0.0431 | 0.1253 |
Toxoplasma gondii | propionate-CoA ligase | 0.0029 | 0.0122 | 0.0207 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0364 | 0.1056 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0122 | 0.013 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.1193 |
Schistosoma mansoni | ap endonuclease | 0.0038 | 0.024 | 0.0698 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0038 | 0.024 | 0.0577 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.3363 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.258 |
Toxoplasma gondii | exonuclease III APE | 0.0038 | 0.024 | 0.0916 |
Echinococcus granulosus | thymidylate synthase | 0.0111 | 0.1178 | 0.2474 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0045 | 0.0335 | 0.0932 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0228 | 0.268 | 0.2589 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.0288 | 0.0837 |
Treponema pallidum | purine nucleoside phosphorylase (deoD) | 0.0059 | 0.0518 | 0.5316 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0059 | 0.0518 | 0.1505 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.3363 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0288 | 0.0501 |
Onchocerca volvulus | 0.0053 | 0.0433 | 0.0936 | |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0248 | 0.0526 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0029 | 0.0122 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.069 | 0.2269 |
Brugia malayi | RNA binding protein | 0.0068 | 0.0623 | 0.181 |
Loa Loa (eye worm) | uridine phosphorylase | 0.0059 | 0.0518 | 0.1623 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.0986 | 0.2863 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0623 | 0.181 |
Brugia malayi | AMP-binding enzyme family protein | 0.0097 | 0.1006 | 0.2922 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0097 | 0.0998 | 0.2054 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0122 | 0.0354 |
Brugia malayi | thymidylate synthase | 0.0111 | 0.1178 | 0.342 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0045 | 0.0335 | 0.0641 |
Echinococcus granulosus | expressed conserved protein | 0.0091 | 0.0923 | 0.1877 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.7784 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0056 | 0.0477 | 0.1204 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0086 | 0.0857 | 0.2488 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0248 | 0.0963 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.1006 | 0.3461 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.7784 |
Leishmania major | methylthioadenosine phosphorylase, putative | 0.0059 | 0.0518 | 0.258 |
Treponema pallidum | uridine phosphorylase (udp) | 0.0059 | 0.0518 | 0.5316 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0248 | 0.0721 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0248 | 0.0526 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0038 | 0.024 | 0.0916 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0096 | 0.0986 | 0.2863 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0097 | 0.1006 | 0.2773 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0248 | 0.0606 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.7784 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.7784 |
Toxoplasma gondii | hypothetical protein | 0.003 | 0.0134 | 0.028 |
Schistosoma mansoni | uridine phosphorylase | 0.0059 | 0.0518 | 0.1505 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0122 | 0.0151 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0056 | 0.0477 | 0.1204 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0857 | 0.2212 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0097 | 0.1006 | 0.2662 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.0288 | 0.0168 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.258 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0623 | 0.181 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.003 | 0.0134 | 0.028 |
Giardia lamblia | Purine nucleoside phosphorylase lateral transfer candidate | 0.0287 | 0.3444 | 0.6896 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0097 | 0.1006 | 0.2773 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0458 | 0.133 |
Brugia malayi | Probable ClpP-like protease | 0.0086 | 0.0857 | 0.2488 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0038 | 0.024 | 0.0503 |
Giardia lamblia | UPL-1 | 0.0059 | 0.0518 | 0.0598 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0045 | 0.0335 | 0.0641 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0097 | 0.1006 | 0.2662 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0233 | 0.2742 | 0.614 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.7784 |
Giardia lamblia | 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase | 0.0059 | 0.0518 | 0.0598 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.0623 | 0.181 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0248 | 0.038 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0248 | 0.038 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0156 | 0.1758 | 1 |
Onchocerca volvulus | Purine nucleoside phosphorylase homolog | 0.0287 | 0.3444 | 1 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0029 | 0.0122 | 0.0207 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0209 | 0.0607 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0029 | 0.0122 | 0.0207 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.0288 | 0.039 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0029 | 0.0122 | 0.0151 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.7784 |
Echinococcus multilocularis | tumor protein p63 | 0.0361 | 0.4389 | 0.432 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.1006 | 0.3461 |
Brugia malayi | hypothetical protein | 0.0233 | 0.2742 | 0.7963 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.0288 | 0.0168 |
Onchocerca volvulus | 0.0097 | 0.1006 | 0.2662 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0639 | 0.1683 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0097 | 0.1006 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.3363 |
Brugia malayi | purine nucleoside phosphorylase I, inosine and guanosine-specific family protein | 0.0287 | 0.3444 | 1 |
Onchocerca volvulus | 0.0038 | 0.0248 | 0.038 | |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.3363 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0248 | 0.0526 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0033 | 0.0176 | 0.0055 |
Echinococcus granulosus | dihydrofolate reductase | 0.0045 | 0.0335 | 0.0499 |
Mycobacterium ulcerans | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 1 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0122 | 0.0151 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0073 | 0.069 | 0.1709 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0111 | 0.1178 | 0.342 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0122 | 0.0151 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0156 | 0.1758 | 1 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0029 | 0.0122 | 0.013 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0029 | 0.0122 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0248 | 0.0606 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0053 | 0.0431 | 0.0932 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0248 | 0.0721 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0248 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0998 | 0.3431 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0138 | 0.1532 | 0.3305 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.1193 |
Entamoeba histolytica | MTA/SAH nucleosidase, putative | 0.0059 | 0.0518 | 0.4483 |
Loa Loa (eye worm) | glutamate receptor | 0.0039 | 0.0258 | 0.0644 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0048 | 0.0375 | 0.0256 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0053 | 0.0433 | 0.1257 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.3363 |
Mycobacterium ulcerans | hypothetical protein | 0.0097 | 0.1006 | 0.2662 |
Loa Loa (eye worm) | S-methyl-5'-thioadenosine phosphorylase MTAP | 0.0059 | 0.0518 | 0.1623 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0248 | 0.038 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0248 | 0.0526 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0248 | 0.0526 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0288 | 0.0757 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0156 | 0.1758 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0209 | 0.0607 |
Loa Loa (eye worm) | hypothetical protein | 0.0233 | 0.2742 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.069 | 0.2269 |
Mycobacterium ulcerans | thymidylate synthase | 0.0111 | 0.1178 | 0.3178 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.0288 | 0.0757 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0097 | 0.1006 | 0.2662 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0097 | 0.1006 | 0.2662 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.0986 | 0.2863 |
Loa Loa (eye worm) | thymidylate synthase | 0.0111 | 0.1178 | 0.4107 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0248 | 0.0526 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0045 | 0.0335 | 0.0215 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0269 | 0.0781 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.1193 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0248 | 0.038 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.0623 | 0.181 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0086 | 0.0857 | 0.4606 |
Echinococcus multilocularis | methylthioadenosine phosphorylase | 0.0059 | 0.0518 | 0.0401 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0029 | 0.0122 | 0.0354 |
Echinococcus granulosus | tar DNA binding protein | 0.0068 | 0.0623 | 0.1175 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0039 | 0.0258 | 0.075 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.003 | 0.0134 | 0.0037 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0623 | 0.181 |
Trichomonas vaginalis | purine nucleoside phosphorylase I, putative | 0.0287 | 0.3444 | 1 |
Brugia malayi | uridine phosphorylase family protein | 0.0059 | 0.0518 | 0.1505 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0038 | 0.024 | 0.0916 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0098 | 0.1018 | 0.2955 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0053 | 0.0431 | 0.206 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0038 | 0.024 | 0.147 |
Onchocerca volvulus | 0.0038 | 0.0248 | 0.038 | |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0156 | 0.1758 | 1 |
Plasmodium vivax | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.258 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0248 | 0.0526 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.4483 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0029 | 0.0122 | 0.013 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0038 | 0.024 | 0.134 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0857 | 0.4606 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0086 | 0.0857 | 0.4606 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0248 | 0.038 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0038 | 0.024 | 0.0916 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0096 | 0.0986 | 0.2025 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0086 | 0.0857 | 0.0744 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0096 | 0.0986 | 0.3385 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.4483 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0097 | 0.1006 | 0.2662 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0248 | 0.0721 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0122 | 0.0207 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0248 | 0.0963 |
Loa Loa (eye worm) | oxidoreductase | 0.0029 | 0.0122 | 0.013 |
Mycobacterium tuberculosis | Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) | 0.0287 | 0.3444 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0038 | 0.024 | 0.0698 |
Echinococcus granulosus | methylthioadenosine phosphorylase | 0.0059 | 0.0518 | 0.0929 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0248 | 0.038 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0287 | 0.3444 | 0.7784 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0086 | 0.0857 | 0.2212 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0038 | 0.024 | 0.0916 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0138 | 0.1532 | 0.1428 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0097 | 0.1006 | 0.2662 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0248 | 0.0606 |
Mycobacterium leprae | probable uridine phosphorylase | 0.0059 | 0.0518 | 0.1193 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0029 | 0.0122 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0248 | 0.0606 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0097 | 0.1006 | 1 |
Mycobacterium ulcerans | 5'-methylthioadenosine phosphorylase | 0.0059 | 0.0518 | 0.1193 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0209 | 0.0607 |
Trypanosoma brucei | methylthioadenosine phosphorylase, putative | 0.0059 | 0.0518 | 0.258 |
Toxoplasma gondii | phosphorylase family protein | 0.0059 | 0.0518 | 0.258 |
Echinococcus granulosus | tumor protein p63 | 0.0361 | 0.4389 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0131 | 0.1439 | 0.4179 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0053 | 0.0431 | 0.1069 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0639 | 0.1683 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0097 | 0.0998 | 0.9911 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0097 | 0.1006 | 0.55 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0122 | 0.0354 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0248 | 0.0296 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0122 | 0.0207 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0857 | 1 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.1193 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0639 | 0.1683 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0033 | 0.0176 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0248 | 0.0606 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0248 | 0.038 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0233 | 0.2742 | 0.2653 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0059 | 0.0518 | 0.1193 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0209 | 0.0984 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0059 | 0.0518 | 0.1505 |
Schistosoma mansoni | ap endonuclease | 0.0038 | 0.024 | 0.0698 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0038 | 0.024 | 0.012 |
Giardia lamblia | 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase | 0.0059 | 0.0518 | 0.0598 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0248 | 0.0606 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0623 | 0.181 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0029 | 0.0122 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.268 | 0.9765 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.003 | 0.0134 | 0.028 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0209 | 0.0984 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0122 | 0.0207 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0073 | 0.069 | 0.68 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
12 literature references were collected for this gene.