Detailed information for compound 587985

Basic information

Technical information
  • TDR Targets ID: 587985
  • Name: formaldehyde; o-cresol
  • MW: 138.164 | Formula: C8H10O2
  • H donors: 1 H acceptors: 2 LogP: 3.17 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccccc1O.C=O
  • InChi: 1S/C7H8O.CH2O/c1-6-4-2-3-5-7(6)8;1-2/h2-5,8H,1H3;1H2
  • InChiKey: VOOLKNUJNPZAHE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • methanal; 2-methylphenol
  • formaldehyde; 2-methylphenol
  • tricresolformalin
  • 102324-87-8
  • 125004-50-4
  • 126039-30-3
  • 25053-96-7
  • 63284-42-4
  • 102382-06-9
  • 107853-33-8
  • 119166-47-1
  • 129429-20-5
  • 161937-42-4
  • 37271-28-6
  • 51601-99-1
  • 59978-72-2
  • 72688-69-8
  • 9016-83-5
  • 9040-15-7
  • 95686-10-5
  • 99149-74-3
  • 2-Methyl phenol, formaldehyde polymer
  • 2-Methylphenol, formaldehyde polymer
  • Formaldehyde, polymer with 2-methylphenol
  • o-Cresol, formaldehyde polymer
  • Cresol, hexamethylenetetramine polymer
  • Cresylic acid, formalin polymer
  • Formaldehyde, polymer with methylphenol
  • Methylphenol, polymer with formaldehyde

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Schistosoma mansoni hypothetical protein 0.0047 0.041 0.0383
Loa Loa (eye worm) hypothetical protein 0.0052 0.0471 0.0798
Loa Loa (eye worm) glutathione reductase 0.0049 0.0436 0.0734
Brugia malayi hypothetical protein 0.0232 0.2702 0.4821
Mycobacterium tuberculosis Possible oxidoreductase 0.0027 0.0163 0.0265
Mycobacterium tuberculosis Probable oxidoreductase 0.0027 0.0163 0.0265
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0027 0.0163 0.0265
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0405 0.4844 1
Echinococcus granulosus muscleblind protein 0.029 0.3419 0.3419
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0027 0.0163 0.3185
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0704 0.1217
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0436 0.0436
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0028 0.0028
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0027 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.029 0.3419 0.6102
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Brugia malayi Muscleblind-like protein 0.029 0.3419 0.6109
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0028 0.0028
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0027 0.0163 0.0243
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0967 0.0967
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.1036 0.1036
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0126 0.2261
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0193 0.0329
Trypanosoma brucei pteridine reductase 1 0.0027 0.0163 0.3185
Brugia malayi Ets-domain containing protein 0.0071 0.0704 0.1233
Onchocerca volvulus 0.0464 0.5585 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0035 0.003
Onchocerca volvulus 0.0058 0.0537 0.0691
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0405 0.4844 1
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0027 0.0163 0.0265
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0027 0.0163 0.3185
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0027 0.0163 0.0163
Plasmodium falciparum enoyl-acyl carrier reductase 0.0405 0.4844 1
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0027 0.0163 0.0265
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0027 0.0163 0.0265
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.1221 0.2466
Mycobacterium tuberculosis Possible oxidoreductase 0.0027 0.0163 0.0265
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0193 0.0193
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0027 0.0163 0.3185
Schistosoma mansoni microtubule-associated protein tau 0.0707 0.8591 0.8587
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0763 0.0763
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Entamoeba histolytica hypothetical protein 0.0076 0.0763 1
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0027 0.0163 0.3185
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0967 0.0942
Plasmodium vivax glutathione reductase, putative 0.0049 0.0436 0.0833
Loa Loa (eye worm) hypothetical protein 0.0051 0.0458 0.0773
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0126 0.0188
Echinococcus granulosus cpg binding protein 0.0061 0.0578 0.0578
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0027 0.0163 0.0265
Plasmodium falciparum glutathione reductase 0.0049 0.0436 0.0833
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0121 0.0094
Brugia malayi Fli-1 protein 0.0216 0.25 0.4457
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0405 0.4844 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.1221 0.2466
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Loa Loa (eye worm) hypothetical protein 0.003 0.0193 0.0297
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0405 0.4844 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.1377 0.2791
Echinococcus granulosus microtubule associated protein 2 0.0707 0.8591 0.8591
Schistosoma mansoni hypothetical protein 0.0036 0.0266 0.0239
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0193 0.0297
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Echinococcus multilocularis peregrin 0.003 0.0193 0.0193
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.2702 0.2702
Schistosoma mansoni cpg binding protein 0.0061 0.0578 0.0552
Entamoeba histolytica hypothetical protein 0.0076 0.0763 1
Schistosoma mansoni cpg binding protein 0.0061 0.0578 0.0552
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0967 0.0967
Plasmodium falciparum phd finger protein, putative 0.003 0.0193 0.0329
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0027 0.0163 0.0265
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0338 0.0338
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0027 0.0163 0.0265
Echinococcus granulosus GPCR family 2 0.0017 0.0028 0.0028
Schistosoma mansoni survival motor neuron protein 0.0047 0.041 0.0383
Schistosoma mansoni gabp alpha 0.0071 0.0704 0.0678
Schistosoma mansoni jumonji domain containing protein 0.0078 0.0786 0.0761
Entamoeba histolytica hypothetical protein 0.0076 0.0763 1
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0027 0.0163 0.0265
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0193 0.0329
Echinococcus granulosus peregrin 0.003 0.0193 0.0193
Brugia malayi Bromodomain containing protein 0.003 0.0193 0.0314
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0027 0.0163 0.0265
Loa Loa (eye worm) hypothetical protein 0.029 0.3419 0.6102
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0163 0.0259
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0028 0.0028
Toxoplasma gondii thioredoxin reductase 0.0049 0.0436 0.0833
Echinococcus multilocularis Protein lozenge 0.0058 0.0545 0.0545
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0044 0.0029
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0704 0.0704
Leishmania major oxidoreductase-like protein 0.0027 0.0163 0.3185
Schistosoma mansoni ets-related 0.0216 0.25 0.2479
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0338 0.0338
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.041 0.0704
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0193 0.0166
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0312 0.0285
Brugia malayi PHD-finger family protein 0.003 0.0193 0.0314
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0027 0.0163 0.0265
Treponema pallidum NADH oxidase 0.0017 0.0035 0.5
Toxoplasma gondii histone lysine methyltransferase SET1 0.0109 0.1176 0.2373
Brugia malayi glutathione reductase 0.0049 0.0436 0.075
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.1377 0.2791
Schistosoma mansoni hypothetical protein 0.0344 0.409 0.4074
Echinococcus multilocularis GPCR, family 2 0.0017 0.0028 0.0028
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0027 0.0163 0.0135
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0036 0.0266 0.0429
Echinococcus multilocularis dnaJ subfamily B 0.082 1 1
Schistosoma mansoni hypothetical protein 0.0344 0.409 0.4074
Trypanosoma brucei oxidoreductase-like protein 0.0027 0.0163 0.3185
Brugia malayi F/Y-rich N-terminus family protein 0.0027 0.0162 0.0258
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.1377 0.2791
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0232 0.2702 0.4812
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0027 0.0163 0.0265
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0436 0.0833
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0312 0.0285
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0028 0.0017
Loa Loa (eye worm) hypothetical protein 0.0024 0.0126 0.0176
Plasmodium vivax hypothetical protein, conserved 0.003 0.0193 0.0329
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0436 0.0734
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0405 0.4844 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0163 0.0259
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0027 0.0163 0.0265
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0027 0.0163 0.0265
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0763 0.0763
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.1221 0.2466
Loa Loa (eye worm) hypothetical protein 0.0061 0.0576 0.0987
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0471 0.0814
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0405 0.4844 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0126 0.0188
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Brugia malayi hypothetical protein 0.0464 0.5585 1
Echinococcus granulosus geminin 0.0344 0.409 0.409
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0967 0.1704
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0471 0.0798
Brugia malayi jmjC domain containing protein 0.0098 0.1036 0.1828
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0027 0.0163 0.0265
Loa Loa (eye worm) oxidoreductase 0.0027 0.0163 0.0243
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0967 0.169
Schistosoma mansoni hypothetical protein 0.082 1 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0044 0.0044
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0027 0.0163 0.0265
Schistosoma mansoni hypothetical protein 0.003 0.0193 0.0166
Schistosoma mansoni dihydropteridine reductase 0.0027 0.0163 0.0135
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0405 0.4844 1
Plasmodium falciparum thioredoxin reductase 0.0049 0.0436 0.0833
Brugia malayi jmjC domain containing protein 0.0039 0.0312 0.0527
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0537 0.0917
Echinococcus multilocularis geminin 0.0344 0.409 0.409
Loa Loa (eye worm) hypothetical protein 0.0464 0.5585 1
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0704 0.0704
Leishmania major pteridine reductase 1 0.0027 0.0163 0.3185
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0126 0.0188
Brugia malayi hypothetical protein 0.0076 0.0763 0.1338
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0967 0.0942
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.1377 0.2594
Echinococcus multilocularis muscleblind protein 1 0.029 0.3419 0.3419
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0035 0.0035
Echinococcus multilocularis muscleblind protein 0.029 0.3419 0.3419
Mycobacterium ulcerans oxidoreductase 0.0027 0.0163 0.0265
Loa Loa (eye worm) retinol dehydrogenase 12 0.0027 0.0163 0.0243
Mycobacterium tuberculosis Probable reductase 0.0113 0.1221 0.2466
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0312 0.0511
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0126 0.2261
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0967 0.0942
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0126 0.0188
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0028 0.0028
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.1036 0.1036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0163 0.0243
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.2702 0.2702
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0266 0.0445
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0163 0.0265
Loa Loa (eye worm) hypothetical protein 0.0464 0.5585 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0471 0.0814
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0027 0.0163 0.3185
Entamoeba histolytica hypothetical protein 0.0076 0.0763 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0035 0.0035
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.1221 0.2466
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0436 1
Schistosoma mansoni hypothetical protein 0.0076 0.0763 0.0738
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0028 0.0017
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.1221 0.2466
Brugia malayi Ets-domain containing protein 0.0071 0.0704 0.1233
Loa Loa (eye worm) runx1 0.0058 0.0545 0.0931
Leishmania major trypanothione reductase 0.0049 0.0436 1
Schistosoma mansoni lozenge 0.0058 0.0545 0.0519
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0035 0.0007
Echinococcus multilocularis microtubule associated protein 2 0.0707 0.8591 0.8591
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.1221 0.2261
Trichomonas vaginalis hypothetical protein 0.0405 0.4844 1
Leishmania major hypothetical protein, conserved 0.0024 0.0126 0.2261
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0044 0.0044
Loa Loa (eye worm) fli-1 protein 0.0216 0.25 0.4448
Trypanosoma brucei trypanothione reductase 0.0049 0.0436 1
Echinococcus multilocularis cpg binding protein 0.0061 0.0578 0.0578
Onchocerca volvulus Alhambra homolog 0.003 0.0193 0.0056
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.1338 0.1314
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0027 0.0163 0.0265
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0027 0.0163 0.3185
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0967 0.0967
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0967 0.0967
Chlamydia trachomatis oxoacy-ACP reductase 0.0027 0.0163 0.0265
Brugia malayi Thioredoxin reductase 0.0049 0.0436 0.075
Brugia malayi CXXC zinc finger family protein 0.0058 0.0537 0.0932
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0027 0.0163 0.0265
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0436 0.0436
Brugia malayi hypothetical protein 0.0024 0.0126 0.0193
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0587 0.1007
Giardia lamblia PHD finger protein 15 0.003 0.0193 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0436 0.0833
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0126 0.2261
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0271 0.0271
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0027 0.0163 0.3185
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0027 0.0163 0.0265
Schistosoma mansoni cpg binding protein 0.0058 0.0537 0.0511
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0763 0.0738
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0027 0.0163 0.0265
Onchocerca volvulus 0.0047 0.041 0.0456

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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