Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.041 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0471 | 0.0798 |
Loa Loa (eye worm) | glutathione reductase | 0.0049 | 0.0436 | 0.0734 |
Brugia malayi | hypothetical protein | 0.0232 | 0.2702 | 0.4821 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0405 | 0.4844 | 1 |
Echinococcus granulosus | muscleblind protein | 0.029 | 0.3419 | 0.3419 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0027 | 0.0163 | 0.3185 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0071 | 0.0704 | 0.1217 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0049 | 0.0436 | 0.0436 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0028 | 0.0028 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0027 | 0.0163 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.3419 | 0.6102 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Brugia malayi | Muscleblind-like protein | 0.029 | 0.3419 | 0.6109 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0027 | 0.0163 | 0.0243 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.0967 | 0.0967 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0098 | 0.1036 | 0.1036 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0126 | 0.2261 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0193 | 0.0329 |
Trypanosoma brucei | pteridine reductase 1 | 0.0027 | 0.0163 | 0.3185 |
Brugia malayi | Ets-domain containing protein | 0.0071 | 0.0704 | 0.1233 |
Onchocerca volvulus | 0.0464 | 0.5585 | 1 | |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0035 | 0.003 |
Onchocerca volvulus | 0.0058 | 0.0537 | 0.0691 | |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0405 | 0.4844 | 1 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0027 | 0.0163 | 0.3185 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0027 | 0.0163 | 0.0163 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0405 | 0.4844 | 1 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0027 | 0.0163 | 0.0265 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0113 | 0.1221 | 0.2466 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0027 | 0.0163 | 0.0265 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.0193 | 0.0193 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0027 | 0.0163 | 0.3185 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0707 | 0.8591 | 0.8587 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0076 | 0.0763 | 0.0763 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0763 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0027 | 0.0163 | 0.3185 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0967 | 0.0942 |
Plasmodium vivax | glutathione reductase, putative | 0.0049 | 0.0436 | 0.0833 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0458 | 0.0773 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.0126 | 0.0188 |
Echinococcus granulosus | cpg binding protein | 0.0061 | 0.0578 | 0.0578 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0027 | 0.0163 | 0.0265 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0436 | 0.0833 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0024 | 0.0121 | 0.0094 |
Brugia malayi | Fli-1 protein | 0.0216 | 0.25 | 0.4457 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0405 | 0.4844 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0113 | 0.1221 | 0.2466 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0193 | 0.0297 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0405 | 0.4844 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0125 | 0.1377 | 0.2791 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0707 | 0.8591 | 0.8591 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0266 | 0.0239 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0193 | 0.0297 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Echinococcus multilocularis | peregrin | 0.003 | 0.0193 | 0.0193 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0232 | 0.2702 | 0.2702 |
Schistosoma mansoni | cpg binding protein | 0.0061 | 0.0578 | 0.0552 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0763 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0061 | 0.0578 | 0.0552 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.0967 | 0.0967 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0193 | 0.0329 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0338 | 0.0338 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0027 | 0.0163 | 0.0265 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0028 | 0.0028 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.041 | 0.0383 |
Schistosoma mansoni | gabp alpha | 0.0071 | 0.0704 | 0.0678 |
Schistosoma mansoni | jumonji domain containing protein | 0.0078 | 0.0786 | 0.0761 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0763 | 1 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.0027 | 0.0163 | 0.0265 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0193 | 0.0329 |
Echinococcus granulosus | peregrin | 0.003 | 0.0193 | 0.0193 |
Brugia malayi | Bromodomain containing protein | 0.003 | 0.0193 | 0.0314 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0027 | 0.0163 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.3419 | 0.6102 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0027 | 0.0163 | 0.0259 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0028 | 0.0028 |
Toxoplasma gondii | thioredoxin reductase | 0.0049 | 0.0436 | 0.0833 |
Echinococcus multilocularis | Protein lozenge | 0.0058 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | histone methyltransferase | 0.0018 | 0.0044 | 0.0029 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0071 | 0.0704 | 0.0704 |
Leishmania major | oxidoreductase-like protein | 0.0027 | 0.0163 | 0.3185 |
Schistosoma mansoni | ets-related | 0.0216 | 0.25 | 0.2479 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0338 | 0.0338 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.041 | 0.0704 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.0193 | 0.0166 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0312 | 0.0285 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0193 | 0.0314 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0027 | 0.0163 | 0.0265 |
Treponema pallidum | NADH oxidase | 0.0017 | 0.0035 | 0.5 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0109 | 0.1176 | 0.2373 |
Brugia malayi | glutathione reductase | 0.0049 | 0.0436 | 0.075 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0125 | 0.1377 | 0.2791 |
Schistosoma mansoni | hypothetical protein | 0.0344 | 0.409 | 0.4074 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0028 | 0.0028 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0027 | 0.0163 | 0.0135 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0039 | 0.0312 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0266 | 0.0429 |
Echinococcus multilocularis | dnaJ subfamily B | 0.082 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0344 | 0.409 | 0.4074 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0027 | 0.0163 | 0.3185 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0027 | 0.0162 | 0.0258 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0125 | 0.1377 | 0.2791 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0193 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.2702 | 0.4812 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0027 | 0.0163 | 0.0265 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0049 | 0.0436 | 0.0833 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0312 | 0.0285 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0028 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0126 | 0.0176 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.0193 | 0.0329 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0049 | 0.0436 | 0.0734 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0405 | 0.4844 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0027 | 0.0163 | 0.0259 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.0027 | 0.0163 | 0.0265 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0076 | 0.0763 | 0.0763 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0113 | 0.1221 | 0.2466 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0576 | 0.0987 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0471 | 0.0814 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0405 | 0.4844 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0126 | 0.0188 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Brugia malayi | hypothetical protein | 0.0464 | 0.5585 | 1 |
Echinococcus granulosus | geminin | 0.0344 | 0.409 | 0.409 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0092 | 0.0967 | 0.1704 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0471 | 0.0798 |
Brugia malayi | jmjC domain containing protein | 0.0098 | 0.1036 | 0.1828 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0027 | 0.0163 | 0.0265 |
Loa Loa (eye worm) | oxidoreductase | 0.0027 | 0.0163 | 0.0243 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0092 | 0.0967 | 0.169 |
Schistosoma mansoni | hypothetical protein | 0.082 | 1 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0018 | 0.0044 | 0.0044 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0027 | 0.0163 | 0.0265 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0193 | 0.0166 |
Schistosoma mansoni | dihydropteridine reductase | 0.0027 | 0.0163 | 0.0135 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0405 | 0.4844 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0436 | 0.0833 |
Brugia malayi | jmjC domain containing protein | 0.0039 | 0.0312 | 0.0527 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0058 | 0.0537 | 0.0917 |
Echinococcus multilocularis | geminin | 0.0344 | 0.409 | 0.409 |
Loa Loa (eye worm) | hypothetical protein | 0.0464 | 0.5585 | 1 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0071 | 0.0704 | 0.0704 |
Leishmania major | pteridine reductase 1 | 0.0027 | 0.0163 | 0.3185 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0126 | 0.0188 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0763 | 0.1338 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0967 | 0.0942 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0125 | 0.1377 | 0.2594 |
Echinococcus multilocularis | muscleblind protein 1 | 0.029 | 0.3419 | 0.3419 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0017 | 0.0035 | 0.0035 |
Echinococcus multilocularis | muscleblind protein | 0.029 | 0.3419 | 0.3419 |
Mycobacterium ulcerans | oxidoreductase | 0.0027 | 0.0163 | 0.0265 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0027 | 0.0163 | 0.0243 |
Mycobacterium tuberculosis | Probable reductase | 0.0113 | 0.1221 | 0.2466 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0039 | 0.0312 | 0.0511 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.0126 | 0.2261 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0967 | 0.0942 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.0126 | 0.0188 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0028 | 0.0028 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0098 | 0.1036 | 0.1036 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0163 | 0.0243 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0232 | 0.2702 | 0.2702 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0266 | 0.0445 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0027 | 0.0163 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0464 | 0.5585 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0471 | 0.0814 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0027 | 0.0163 | 0.3185 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0763 | 1 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0017 | 0.0035 | 0.0035 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0113 | 0.1221 | 0.2466 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0436 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0763 | 0.0738 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0028 | 0.0017 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0113 | 0.1221 | 0.2466 |
Brugia malayi | Ets-domain containing protein | 0.0071 | 0.0704 | 0.1233 |
Loa Loa (eye worm) | runx1 | 0.0058 | 0.0545 | 0.0931 |
Leishmania major | trypanothione reductase | 0.0049 | 0.0436 | 1 |
Schistosoma mansoni | lozenge | 0.0058 | 0.0545 | 0.0519 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.0035 | 0.0007 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0707 | 0.8591 | 0.8591 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0113 | 0.1221 | 0.2261 |
Trichomonas vaginalis | hypothetical protein | 0.0405 | 0.4844 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0126 | 0.2261 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0018 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | fli-1 protein | 0.0216 | 0.25 | 0.4448 |
Trypanosoma brucei | trypanothione reductase | 0.0049 | 0.0436 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0061 | 0.0578 | 0.0578 |
Onchocerca volvulus | Alhambra homolog | 0.003 | 0.0193 | 0.0056 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0122 | 0.1338 | 0.1314 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0027 | 0.0163 | 0.0265 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0027 | 0.0163 | 0.3185 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.0967 | 0.0967 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.0967 | 0.0967 |
Chlamydia trachomatis | oxoacy-ACP reductase | 0.0027 | 0.0163 | 0.0265 |
Brugia malayi | Thioredoxin reductase | 0.0049 | 0.0436 | 0.075 |
Brugia malayi | CXXC zinc finger family protein | 0.0058 | 0.0537 | 0.0932 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0027 | 0.0163 | 0.0265 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0049 | 0.0436 | 0.0436 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0126 | 0.0193 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.0587 | 0.1007 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.0193 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0049 | 0.0436 | 0.0833 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0126 | 0.2261 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0271 | 0.0271 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0027 | 0.0163 | 0.3185 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.0027 | 0.0163 | 0.0265 |
Schistosoma mansoni | cpg binding protein | 0.0058 | 0.0537 | 0.0511 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0076 | 0.0763 | 0.0738 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0027 | 0.0163 | 0.0265 |
Onchocerca volvulus | 0.0047 | 0.041 | 0.0456 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.