Detailed information for compound 588295

Basic information

Technical information
  • TDR Targets ID: 588295
  • Name: 2,5,8,8-tetramethyl-1,4,4a,7,9,9a-hexahydrobe nzo[7]annulene
  • MW: 204.351 | Formula: C15H24
  • H donors: 0 H acceptors: 0 LogP: 4.14 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1=CCC2C(C1)CC(C)(C)CC=C2C
  • InChi: 1S/C15H24/c1-11-5-6-14-12(2)7-8-15(3,4)10-13(14)9-11/h5,7,13-14H,6,8-10H2,1-4H3
  • InChiKey: NHWVMXZZAZDCIV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2,5,8,8-tetramethyl-1,4,4a,7,9,9a-hexahydrobenzocycloheptene
  • N(6)-(N-threonylcarbonyl)adenosine
  • 24703-35-3
  • Bicyclo(8.1.0)undeca-2,6-diene, 3,7,11,11-tetramethyl-, (1S-(1R*,2E,6E,10S*))-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0612
Loa Loa (eye worm) hypothetical protein 0.0144 0.1117 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0086 0.0767
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0066 0.0066
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0068 0.0011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0119 0.1068
Onchocerca volvulus 0.0144 0.1117 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0119 0.1462
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0024 0.0185
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0066 0.0593
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0086 0.0086
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0443 0.3968
Mycobacterium tuberculosis Probable lipase LipE 0.0144 0.1117 0.1406
Brugia malayi isocitrate dehydrogenase 0.0018 0.0066 0.0593
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0086 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0102 0.0764 0.6835
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0318 0.0937
Brugia malayi cathepsin L-like precursor 0.0011 0.0009 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0119 0.0486
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0054 0.045
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.1117 1
Echinococcus multilocularis GPCR, family 2 0.0016 0.0048 0.0048
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.0808 0.0808
Echinococcus granulosus FTZ F1 alpha 0.0404 0.3278 0.3278
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0172 0.1369
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0144 0.1117 0.1406
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0009 0.0009
Plasmodium falciparum zinc finger protein, putative 0.001 0.0001 0.0018
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0006 0.0058
Brugia malayi ecdysteroid receptor 0.002 0.0086 0.0767
Brugia malayi Cathepsin L-like precursor 0.0016 0.0054 0.0484
Mycobacterium tuberculosis Probable lipase LipD 0.0144 0.1117 0.1406
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0006 0.0058
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0054 0.0653
Trypanosoma cruzi hypothetical protein, conserved 0.0418 0.3389 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0119 0.1068
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0066 0.0526
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0266 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0086 0.0767
Mycobacterium tuberculosis Conserved protein 0.0144 0.1117 0.1406
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0048 0.0318 0.2376
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0767
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0054 0.0712
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0058
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0318 0.2376
Brugia malayi Cathepsin L-like precursor 0.0016 0.0054 0.0484
Loa Loa (eye worm) hypothetical protein 0.0052 0.0354 0.317
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0672 0.0672
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0024 0.0286
Toxoplasma gondii histone lysine methyltransferase SET1 0.0161 0.1259 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0177 0.0177
Leishmania major cathepsin L-like protease 0.0016 0.0054 0.016
Loa Loa (eye worm) RecQ helicase 0.0024 0.0117 0.1051
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0226 0.0226
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.076 0.2242
Schistosoma mansoni nuclear hormone receptor 0.002 0.0086 0.0086
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0051 0.0407
Schistosoma mansoni hypothetical protein 0.0031 0.0172 0.0172
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0102 0.0764 0.0764
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0004 0.00000000030516
Mycobacterium tuberculosis Conserved protein 0.0048 0.0318 0.0342
Echinococcus multilocularis cysteine protease 0.0016 0.0054 0.0054
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0086 0.0086
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0086 0.0086
Brugia malayi hypothetical protein 0.0011 0.0006 0.0058
Brugia malayi Cathepsin L-like precursor 0.0016 0.0054 0.0484
Brugia malayi jmjC domain containing protein 0.0042 0.0266 0.2383
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0044 0.0396
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0009 0.0095
Echinococcus granulosus peregrin 0.0031 0.0172 0.0172
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0073 0.5
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0144 0.1117 0.1117
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0054 0.0484
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0326 0.0961
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0086 0.0767
Mycobacterium leprae Probable lipase LipE 0.0144 0.1117 1
Brugia malayi AF-10 protein 0.001 0.0001 0.0009
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0144 0.1117 1
Schistosoma mansoni hypothetical protein 0.0016 0.0048 0.0048
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0094 0.0094
Brugia malayi jmjC domain containing protein 0.01 0.0751 0.6726
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0078 0.0668
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0612
Loa Loa (eye worm) hypothetical protein 0.0101 0.076 0.6801
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0672 0.0672
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0318 0.2376
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0006 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0119 0.0352
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0053 0.0473
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0086 0.0691
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0086 0.0767
Schistosoma mansoni myst-related protein 0.001 0.0001 0.0001
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.076 0.6034
Mycobacterium tuberculosis Conserved protein 0.0144 0.1117 0.1406
Loa Loa (eye worm) hypothetical protein 0.0016 0.0048 0.0428
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0923 0.826
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.01 0.0751 0.0751
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0054 0.045
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0767
Brugia malayi hypothetical protein 0.0101 0.076 0.6801
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0073 0.0073
Leishmania major cathepsin L-like protease 0.0016 0.0054 0.016
Mycobacterium ulcerans hypothetical protein 0.0024 0.0119 0.0486
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0794 0.6514 0.6514
Leishmania major cathepsin L-like protease 0.0062 0.0437 0.1289
Onchocerca volvulus 0.0016 0.0054 0.0406
Mycobacterium ulcerans beta-lactamase 0.0144 0.1117 1
Onchocerca volvulus 0.0016 0.0054 0.0406
Schistosoma mansoni ap endonuclease 0.0019 0.0073 0.0073
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0024 0.0072
Trichomonas vaginalis penicillin-binding protein, putative 0.0144 0.1117 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0073 0.4214
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0016 0.0048 0.0048
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0048 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0086 0.0767
Schistosoma mansoni cpg binding protein 0.009 0.0666 0.0666
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0119 0.1068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0767
Trypanosoma cruzi hypothetical protein, conserved 0.0144 0.1117 0.3296
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0144 0.1117 1
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0086 0.0767
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0066 0.0066
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0068 0.5
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0102 0.0764 0.0764
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.1117 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0102 0.0764 0.6835
Echinococcus multilocularis FTZ F1 alpha 0.0102 0.0764 0.0764
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0437 0.1289
Schistosoma mansoni coup transcription factor 0.002 0.0086 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0066 0.0593
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0073 0.0618
Mycobacterium ulcerans hypothetical protein 0.0144 0.1117 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0172 0.0172
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0172 0.1543
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0054 0.0054
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0266 0.2383
Plasmodium falciparum phd finger protein, putative 0.0031 0.0172 0.2268
Brugia malayi steroid hormone receptor 0.002 0.0086 0.0767
Echinococcus granulosus cathepsin l1 0.0016 0.0054 0.0054
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.01 0.0751 0.0751
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0015 0.004 0.004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0054 0.0054
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0073 0.0651
Brugia malayi hypothetical protein 0.0011 0.0006 0.0058
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0922 0.7579 1
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0437 0.1289
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0172 0.0172
Entamoeba histolytica hypothetical protein 0.0107 0.0808 1
Brugia malayi Bromodomain containing protein 0.0031 0.0172 0.1543
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0009 0.0046
Brugia malayi Cathepsin L-like precursor 0.0011 0.0009 0.0081
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0054 0.0712
Schistosoma mansoni hypothetical protein 0.0034 0.0199 0.0199
Leishmania major cathepsin L-like protease 0.0016 0.0054 0.016
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0081
Loa Loa (eye worm) hypothetical protein 0.0144 0.1117 1
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0001 0.0008
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0295 0.0295
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0086 0.0767
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0054 0.045
Brugia malayi beta-lactamase 0.0144 0.1117 1
Echinococcus granulosus geminin 0.0343 0.2772 0.2772
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0054 0.0653
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0272 0.0272
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0119 0.0079
Entamoeba histolytica hypothetical protein 0.0107 0.0808 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0137 0.0137
Leishmania major cathepsin L-like protease 0.0016 0.0054 0.016
Trichomonas vaginalis helicase, putative 0.0019 0.0078 0.0668
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0181 0.1419 0.1419
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0078 0.0668
Echinococcus granulosus beta LACTamase domain containing family member 0.0144 0.1117 0.1117
Loa Loa (eye worm) hypothetical protein 0.0024 0.0119 0.1068
Leishmania major hypothetical protein, conserved 0.0418 0.3389 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0021 0.0094 0.0094
Schistosoma mansoni hypothetical protein 0.0107 0.0808 0.0808
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0328 0.294
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0119 0.0079
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0073 0.0073
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0672 0.0672
Schistosoma mansoni cpg binding protein 0.0085 0.0626 0.0626
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.076 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0086 0.0767
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0054 0.0484
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0015 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0054 0.045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0266 0.0266
Mycobacterium ulcerans hypothetical protein 0.0048 0.0318 0.2376
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0054 0.0054
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0086 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0144 0.1117 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0058
Leishmania major cathepsin L-like protease 0.0062 0.0437 0.1289
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.001 0.0001 0.0008
Echinococcus granulosus cpg binding protein 0.009 0.0666 0.0666
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0117 0.102
Loa Loa (eye worm) beta-lactamase 0.0144 0.1117 1
Plasmodium vivax vivapain-2 0.0016 0.0054 0.0484
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0048 0.0428
Toxoplasma gondii cathepsin CPL 0.0016 0.0054 0.0429
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0006 0.0058
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0075 0.0075
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0086 0.0086
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0119 0.0486
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0086 0.0767
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0066 0.0066
Brugia malayi PHD-finger family protein 0.0015 0.0041 0.0371
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0437 0.1289
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0086 0.0767
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0078 0.0668
Schistosoma mansoni cpg binding protein 0.009 0.0666 0.0666
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0172 0.1369
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0078 0.0668
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0081
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0328 0.294
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0054 0.0406
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0078 0.0668
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0767
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0086 0.0767
Brugia malayi hypothetical protein 0.0065 0.0461 0.413
Schistosoma mansoni hypothetical protein 0.1213 1 1
Onchocerca volvulus 0.0024 0.0119 0.0996
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0073 0.0958
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0086 0.0767
Leishmania major hypothetical protein, conserved 0.0144 0.1117 0.3296
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0021 0.0094 0.0094
Brugia malayi nuclear hormone receptor 0.002 0.0086 0.0767
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0078 0.0668
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0058
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0086 0.0767
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0172 0.0172
Brugia malayi beta-lactamase family protein 0.0144 0.1117 1
Echinococcus multilocularis cysteine protease 0.0016 0.0054 0.0054
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0015 0.0044 0.0582
Giardia lamblia PHD finger protein 15 0.0031 0.0172 1
Schistosoma mansoni hypothetical protein 0.0082 0.0596 0.0596
Trypanosoma cruzi hypothetical protein, conserved 0.0144 0.1117 0.3296
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0006 0.0006
Onchocerca volvulus Alhambra homolog 0.0031 0.0172 0.1474
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0048 0.0428
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0086 0.0767
Loa Loa (eye worm) CXXC zinc finger family protein 0.0085 0.0626 0.5602
Loa Loa (eye worm) hypothetical protein 0.0034 0.0199 0.1777
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0078 0.0668
Leishmania major cathepsin L-like protease 0.0016 0.0054 0.016
Brugia malayi Cathepsin L-like precursor 0.0016 0.0054 0.0484
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0048 0.0048
Brugia malayi hypothetical protein 0.0107 0.0808 0.7233
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0073 0.0215
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0054 0.0712
Brugia malayi MH2 domain containing protein 0.0121 0.0923 0.826
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0068 0.0612
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0054 0.016
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0054 0.016
Plasmodium vivax hypothetical protein, conserved 0.0144 0.1117 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0 0.0002
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0066 0.0066
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0016 0.0048 0.0048
Schistosoma mansoni hypothetical protein 0.0016 0.0048 0.0048
Schistosoma mansoni thyroid hormone receptor 0.002 0.0086 0.0086
Echinococcus multilocularis citrate lyase subunit beta protein 0.0048 0.0318 0.0318
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0612
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0086 0.0691
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0073 0.5
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0119 0.0486
Echinococcus multilocularis cpg binding protein 0.009 0.0666 0.0666
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0009 0.0081
Echinococcus multilocularis beta LACTamase domain containing family member 0.0144 0.1117 0.1117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Leishmania major cathepsin L-like protease 0.0062 0.0437 0.1289
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0078 0.0668
Loa Loa (eye worm) hypothetical protein 0.0024 0.0119 0.1068
Schistosoma mansoni hypothetical protein 0.0343 0.2772 0.2772
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.0808 0.0808
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0073 0.0651
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0144 0.1117 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0078 0.0668
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0078 0.0668
Plasmodium vivax vivapain-2 0.0016 0.0054 0.0484
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0054 0.0054
Onchocerca volvulus 0.0016 0.0054 0.0406
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0371
Onchocerca volvulus 0.0016 0.0054 0.0406
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0054 0.045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Echinococcus multilocularis dnaJ subfamily B 0.1213 1 1
Mycobacterium tuberculosis Probable esterase LipL 0.0144 0.1117 0.1406
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0093 0.1227
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0119 0.1068
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.076 0.2242
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0058
Brugia malayi PHD-finger family protein 0.0031 0.0172 0.1543
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0119 0.0352
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0081
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0328 0.294
Onchocerca volvulus 0.0144 0.1117 1
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0121 0.0922 0.8258
Loa Loa (eye worm) ctsf protein 0.0016 0.0054 0.0484
Loa Loa (eye worm) hypothetical protein 0.0144 0.1117 1
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0054 0.0406
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0086 0.0086
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0068 0.09
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0102 0.0764 0.6835
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0078 0.0668
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0119 0.0352
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0672 0.0672
Onchocerca volvulus 0.0016 0.0054 0.0406
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0073 0.0618
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0672 0.0672
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0119 0.0486
Loa Loa (eye worm) hypothetical protein 0.0049 0.0328 0.294
Onchocerca volvulus 0.002 0.0086 0.0691
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Onchocerca volvulus 0.0085 0.0626 0.5566
Leishmania major hypothetical protein, conserved 0.0101 0.076 0.2242
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0066 0.0872
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0086 0.0086
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0086 0.0086
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0102 0.0764 0.0764
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0048 0.0048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0054 0.045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Brugia malayi nuclear receptor RXR 0.0011 0.0006 0.0058
Trichomonas vaginalis esterase, putative 0.0144 0.1117 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0172 0.1543
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0054 0.045
Trichomonas vaginalis penicillin-binding protein, putative 0.0144 0.1117 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0094 0.0094
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0144 0.1117 0.1406
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0923 0.826
Brugia malayi Cathepsin L-like precursor 0.0016 0.0054 0.0484
Onchocerca volvulus 0.0016 0.0054 0.0406
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0672 0.0672
Entamoeba histolytica hypothetical protein 0.0107 0.0808 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0086 0.0086
Loa Loa (eye worm) cysteine protease 0.0016 0.0054 0.0484
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0767
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0054 0.045
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0343 0.2772 0.2772
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0144 0.1117 0.1406
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0318 0.0937
Echinococcus granulosus citrate lyase subunit beta protein 0.0048 0.0318 0.0318
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0073 0.0041
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.076 0.2242
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0066 0.0066
Trypanosoma brucei hypothetical protein, conserved 0.0418 0.3389 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0073 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0009 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Echinococcus granulosus bloom syndrome protein 0.0024 0.0117 0.0117
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0073 0.0215
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0073 0.0651
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0172 0.1543
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0054 0.0054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0054 0.045
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0318 0.0937
Loa Loa (eye worm) histone methyltransferase 0.0026 0.0137 0.1225
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0086 0.0086
Schistosoma mansoni myst-related protein 0.001 0.0001 0.0001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0119 0.1462
Trypanosoma cruzi hypothetical protein, conserved 0.0418 0.3389 1
Loa Loa (eye worm) hypothetical protein 0.0144 0.1117 1
Echinococcus multilocularis geminin 0.0343 0.2772 0.2772
Mycobacterium tuberculosis Probable hydrolase 0.0144 0.1117 0.1406
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0117 0.102
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0272 0.0272
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0016 0.0054 0.0484
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0119 0.0486
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0078 0.0668
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0066 0.0196
Trypanosoma brucei hypothetical protein, conserved 0.0144 0.1117 0.3296
Brugia malayi nuclear receptor NHR-88 0.002 0.0086 0.0767
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0437 0.1289
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0048 0.0318 0.0342
Brugia malayi Cathepsin L-like precursor 0.0011 0.0009 0.0081
Entamoeba histolytica cysteine protease, putative 0.0016 0.0054 0.0653
Mycobacterium ulcerans esterase/lipase LipP 0.0144 0.1117 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0054 0.045
Toxoplasma gondii ABC1 family protein 0.0144 0.1117 0.8873
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0199 0.1777
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0086 0.0767
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0086 0.0767
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0672 0.6012
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0144 0.1117 0.1117
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0054 0.0406
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0054 0.045
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Entamoeba histolytica hypothetical protein 0.0107 0.0808 1
Schistosoma mansoni hypothetical protein 0.0045 0.0295 0.0295
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0086 0.0767
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0078 0.0668
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0144 0.1117 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0054 0.0484
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0066 0.0196
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0086 0.0767
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0672 0.0672
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0078 0.0668
Toxoplasma gondii exonuclease III APE 0.0019 0.0073 0.0578
Mycobacterium ulcerans hypothetical protein 0.0048 0.0318 0.2376
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0066 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0119 0.0486
Onchocerca volvulus 0.0144 0.1117 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0086 0.0086
Loa Loa (eye worm) fibroinase 0.0016 0.0054 0.0484
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0066 0.0196
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.076 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0086 0.0767
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0066 0.0066
Schistosoma mansoni thyroid hormone receptor 0.002 0.0086 0.0086
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0086 0.0767
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0217 0.1945
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0024 0.0072
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0137 0.0137
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0117 0.1051
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0066 0.0196
Mycobacterium ulcerans lipase LipD 0.0144 0.1117 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0295 0.0295
Echinococcus multilocularis peregrin 0.0031 0.0172 0.0172
Mycobacterium leprae conserved hypothetical protein 0.0144 0.1117 1
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0086 0.0086
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0078 0.0668
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0073 0.0885
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0086 0.0767
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.1117 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0086 0.0086
Brugia malayi CXXC zinc finger family protein 0.0085 0.0626 0.5602
Brugia malayi Cathepsin L-like precursor 0.0016 0.0054 0.0484
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0066 0.0526
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0054 0.045
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0073 0.0215
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Brugia malayi beta-lactamase family protein 0.0144 0.1117 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0767
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0048 0.0428
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0066 0.0066
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0 0.0002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0073 0.0215
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.0808 0.0808
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.076 0.6801
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0612
Schistosoma mansoni ap endonuclease 0.0019 0.0073 0.0073
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0 0.0003
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0672 0.6012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0086 0.0767
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0066 0.0593
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0612
Echinococcus granulosus cathepsin l1 0.0011 0.0009 0.0009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0078 0.0668
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0066 0.0196
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.002 0.0086 0.0767
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0078 0.0668
Schistosoma mansoni jumonji domain containing protein 0.008 0.058 0.058
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0048 0.0318 0.2818
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0119 0.1462
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0024 0.0072
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0392 0.1156
Echinococcus granulosus GPCR family 2 0.0016 0.0048 0.0048
Onchocerca volvulus 0.0016 0.0054 0.0406
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0086 0.0691
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0437 0.1289
Mycobacterium tuberculosis Conserved protein 0.0144 0.1117 0.1406
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0119 0.0486

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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