Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 | 0.0022 | 0.1667 | 0.1667 |
Mycobacterium tuberculosis | Probable aminopeptidase PepB | 0.0109 | 1 | 1 |
Loa Loa (eye worm) | aminopeptidase in chromosome III | 0.0022 | 0.1667 | 0.4063 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.3267 | 0.5639 |
Toxoplasma gondii | leucyl aminopeptidase LAP | 0.0109 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.3267 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.5793 | 1 |
Brugia malayi | cytosol aminopeptidase | 0.0022 | 0.1667 | 0.4063 |
Trypanosoma brucei | metallo-peptidase, Clan MF, Family M17 | 0.0022 | 0.1667 | 0.1667 |
Trichomonas vaginalis | calcineurin B subunit, putative | 0.0004 | 0 | 0.5 |
Loa Loa (eye worm) | aminopeptidase in chromosome V | 0.0022 | 0.1667 | 0.4063 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 | 0.0022 | 0.1667 | 0.1667 |
Trypanosoma cruzi | metallo-peptidase, Clan MF, Family M17 | 0.0022 | 0.1667 | 0.1667 |
Leishmania major | cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 | 0.0109 | 1 | 1 |
Brugia malayi | Aminopeptidase ZK353.6 in chromosome III | 0.0022 | 0.1667 | 0.4063 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.5793 | 1 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 | 0.0022 | 0.1667 | 0.1667 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.4104 | 0.7084 |
Trypanosoma cruzi | metallo-peptidase, Clan MF, Family M17, putative | 0.0109 | 1 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0065 | 0.5793 | 0.5793 |
Wolbachia endosymbiont of Brugia malayi | leucyl aminopeptidase | 0.0109 | 1 | 0.5 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0022 | 0.1667 | 0.4063 |
Plasmodium falciparum | M17 leucyl aminopeptidase | 0.0109 | 1 | 0.5 |
Echinococcus multilocularis | leucine aminopeptidase protein | 0.0109 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0038 | 0.3267 | 0.796 |
Schistosoma mansoni | leucine aminopeptidase | 0.0022 | 0.1667 | 0.2878 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.4104 | 0.7084 |
Plasmodium vivax | M17 leucyl aminopeptidase, putative | 0.0109 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.3267 | 0.3267 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.4104 | 1 |
Mycobacterium leprae | Probable cytosol aminopeptidase PepB | 0.0109 | 1 | 0.5 |
Trichomonas vaginalis | calmodulin, putative | 0.0004 | 0 | 0.5 |
Trypanosoma brucei | aminopeptidase, putative | 0.0022 | 0.1667 | 0.1667 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.3267 | 1 |
Trypanosoma cruzi | cytosolic leucyl aminopeptidase, putative | 0.0109 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0004 | 0 | 0.5 |
Echinococcus multilocularis | leucyl aminopeptidase | 0.0022 | 0.1667 | 0.1667 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.4104 | 0.4104 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.3267 | 0.5639 |
Schistosoma mansoni | PwLAP aminopeptidase (M17 family) | 0.0022 | 0.1667 | 0.2878 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.4104 | 0.4104 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.4104 | 0.4104 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0065 | 0.5793 | 0.5793 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.3267 | 1 |
Mycobacterium ulcerans | leucyl aminopeptidase | 0.0109 | 1 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MF, Family M17 | 0.0022 | 0.1667 | 0.1667 |
Trypanosoma brucei | metallo-peptidase, Clan MF, Family M17 | 0.0022 | 0.1667 | 0.1667 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0065 | 0.5793 | 0.5793 |
Brugia malayi | Aminopeptidase W07G4.4 in chromosome V | 0.0022 | 0.1667 | 0.4063 |
Echinococcus granulosus | leucyl aminopeptidase | 0.0022 | 0.1667 | 0.1667 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.4104 | 0.7084 |
Echinococcus granulosus | leucyl aminopeptidase | 0.0022 | 0.1667 | 0.1667 |
Echinococcus multilocularis | leucyl aminopeptidase | 0.0022 | 0.1667 | 0.1667 |
Trypanosoma brucei | metallo-peptidase, Clan MF, Family M17 | 0.0109 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.4104 | 1 |
Echinococcus granulosus | leucine aminopeptidase protein | 0.0109 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.3267 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.4104 | 0.4104 |
Onchocerca volvulus | 0.0004 | 0 | 0.5 | |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.3267 | 0.3267 |
Echinococcus granulosus | ankyrin repeat domain containing protein 17 | 0.0022 | 0.1667 | 0.1667 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0065 | 0.5793 | 0.5793 |
Echinococcus multilocularis | leucyl aminopeptidase | 0.0022 | 0.1667 | 0.1667 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.