Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0165 | 0.1668 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.026 | 0.026 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.026 | 0.026 |
Echinococcus multilocularis | dna polymerase eta | 0.0046 | 0.2595 | 0.2595 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0609 | 0.2348 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0609 | 0.2348 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0912 | 0.9104 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0744 | 0.1066 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.285 | 0.4084 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.6977 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.6977 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.3471 | 0.3471 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0006 | 0.0147 | 0.0479 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0912 | 0.1307 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0006 | 0.0147 | 0.0568 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0912 | 0.9238 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Brugia malayi | MH1 domain containing protein | 0.0004 | 0.0041 | 0.0059 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0165 | 0.1668 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.285 | 0.4084 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0912 | 0.9238 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0912 | 0.9238 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0744 | 0.0744 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0302 | 0.0433 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0203 | 0.0203 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0165 | 0.1668 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1875 | 0.2687 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.026 | 0.026 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0987 | 0.0987 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1875 | 0.1875 |
Schistosoma mansoni | smad | 0.0008 | 0.026 | 0.026 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.026 | 0.0373 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0006 | 0.0147 | 0.0568 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0032 | 0.1755 | 0.6763 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.1614 | 0.1614 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0987 | 0.3805 |
Brugia malayi | polk-prov protein | 0.0006 | 0.0147 | 0.0211 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0006 | 0.0147 | 0.1615 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.0609 | 0.2348 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0912 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Brugia malayi | Smad1 | 0.0008 | 0.026 | 0.0373 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.6977 | 1 |
Giardia lamblia | DNA damage repair protein | 0.0006 | 0.0147 | 0.1492 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0987 | 0.0987 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0987 | 0.1415 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.2595 | 0.372 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.026 | 0.026 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.026 | 0.026 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.285 | 0.4084 |
Leishmania major | DNA polymerase kappa, putative | 0.0006 | 0.0147 | 0.0568 |
Schistosoma mansoni | DNA polymerase eta | 0.0046 | 0.2595 | 0.2595 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.026 | 0.026 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0987 | 0.3805 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.1515 | 0.1515 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0987 | 0.0987 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0912 | 0.3515 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0165 | 0.1668 |
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0912 | 0.3515 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.1614 | 0.1614 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.285 | 0.4084 |
Brugia malayi | MH1 domain containing protein | 0.0004 | 0.0041 | 0.0059 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0912 | 0.2966 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0912 | 0.9238 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0987 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.026 | 0.0373 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0987 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0165 | 0.1668 |
Leishmania major | DNA polymerase eta, putative | 0.0046 | 0.2595 | 1 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0912 | 0.9238 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.1614 | 0.1614 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.1614 | 0.1614 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0987 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0165 | 0.1668 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0006 | 0.0147 | 0.0568 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0046 | 0.2595 | 0.372 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0006 | 0.0147 | 0.0147 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0987 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0006 | 0.0147 | 0.0479 |
Leishmania major | DNA damage repair protein, putative | 0.0006 | 0.0147 | 0.0568 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0744 | 0.0744 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0006 | 0.0147 | 0.0568 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0912 | 0.0912 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.026 | 0.026 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0006 | 0.0147 | 0.0568 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0165 | 0.1668 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0165 | 0.1668 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0987 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0165 | 0.1668 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.026 | 0.026 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.3076 | 1 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.026 | 0.0373 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0165 | 0.1668 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.1515 | 0.2171 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0203 | 0.0203 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.0912 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0309 | 0.0309 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0203 | 0.0203 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0609 | 0.2348 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0165 | 0.1668 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0006 | 0.0147 | 0.0568 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0987 | 0.0987 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0744 | 0.1066 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0912 | 0.3515 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0046 | 0.2595 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0165 | 0.1668 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0006 | 0.0147 | 0.0568 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0987 | 0.3805 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0046 | 0.2595 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0987 | 0.1415 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0165 | 0.1668 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.026 | 0.0373 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0912 | 0.0912 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.026 | 0.0373 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0912 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0744 | 0.0744 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0006 | 0.0147 | 0.1615 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0006 | 0.0147 | 0.0568 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0744 | 0.0744 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0309 | 0.0309 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0744 | 0.0744 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0912 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0309 | 0.0443 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0744 | 0.0744 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0744 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0147 | 0.0211 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.0609 | 0.2348 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0912 | 0.1307 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.002 | 0.002 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0987 | 0.0987 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Echinococcus multilocularis | smad | 0.0008 | 0.026 | 0.026 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0744 | 0.0744 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0744 | 0.1066 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.0041 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0165 | 0.1668 |
Loa Loa (eye worm) | nuclear factor I | 0.0004 | 0.0041 | 0.0059 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0165 | 0.1668 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0032 | 0.1755 | 0.5707 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0912 | 0.0912 |
Echinococcus granulosus | smad | 0.0008 | 0.026 | 0.026 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0912 | 0.0912 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0165 | 0.1668 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0744 | 0.0744 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.0987 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0987 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0744 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0744 | 0.1066 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.026 | 0.0373 |
Leishmania major | DNA polymerase eta, putative | 0.0032 | 0.1755 | 0.6763 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0987 | 0.3805 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0987 | 0.0987 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0987 | 0.3805 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0987 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0203 | 0.0203 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.026 | 0.0373 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0006 | 0.0147 | 0.0568 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.026 | 0.026 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0912 | 0.3515 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.026 | 0.026 |
Echinococcus granulosus | dna polymerase eta | 0.0046 | 0.2595 | 0.2595 |
Onchocerca volvulus | 0.0028 | 0.1515 | 1 | |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0165 | 0.1668 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.1515 | 0.2171 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0203 | 0.0203 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0987 | 0.3805 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0006 | 0.0147 | 0.0568 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1875 | 0.2687 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0006 | 0.0147 | 0.0568 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0165 | 0.1668 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.026 | 0.026 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.