Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0136 | 0.485 | 0.9236 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0377 | 0.0845 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0044 | 0.1142 | 0.2565 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.5251 | 0.5251 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.5251 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0265 | 1 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0126 | 0.4451 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0044 | 0.1142 | 0.2565 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.5251 | 1 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0044 | 0.1142 | 0.2565 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0075 | 0.0167 |
Schistosoma mansoni | glutaminase | 0.0265 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.1323 | 0.1323 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0032 | 0.0676 | 0.0676 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0044 | 0.1142 | 0.2565 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0118 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1323 | 0.1323 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0177 | 0.0337 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0177 | 0.0337 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0044 | 0.1142 | 0.2565 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.5251 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0038 | 0.0083 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0177 | 0.0337 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0177 | 0.0177 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0177 | 0.0337 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0033 | 0.0719 | 0.1614 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0126 | 0.4451 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0044 | 0.1142 | 0.2565 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0044 | 0.1142 | 0.2565 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0044 | 0.1142 | 0.1037 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0075 | 0.0167 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0044 | 0.1142 | 0.2175 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1397 | 0.1397 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0075 | 0.0075 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.1028 | 0.1028 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0001 | 0.0002 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0044 | 0.1142 | 0.2565 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.0001 | 0.0002 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0044 | 0.1142 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0969 | 0.0969 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0177 | 0.0177 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0308 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.5251 | 0.5251 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0033 | 0.0719 | 0.1614 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0044 | 0.1142 | 0.2565 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0118 | 0.0262 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0308 | 0.0308 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0126 | 0.4451 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.5251 | 0.5251 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0001 | 0.0001 |
Onchocerca volvulus | 0.0148 | 0.5319 | 1 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0177 | 0.0177 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0177 | 0.0177 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0044 | 0.1142 | 0.2565 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0118 | 0.0224 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0177 | 0.0337 |
Leishmania major | trypanothione reductase | 0.0126 | 0.4451 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0308 | 0.069 |
Brugia malayi | glutathione reductase | 0.0126 | 0.4451 | 0.4451 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0044 | 0.1142 | 0.2565 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0177 | 0.0177 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0308 | 0.069 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0033 | 0.0719 | 0.1614 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0118 | 0.0118 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0038 | 0.0083 |
Brugia malayi | Thioredoxin reductase | 0.0126 | 0.4451 | 0.4451 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.2978 | 0.5671 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0044 | 0.1142 | 0.2565 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0177 | 0.0337 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0044 | 0.1142 | 0.2565 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0969 | 0.0969 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.1323 | 0.1323 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0044 | 0.1142 | 0.2565 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0044 | 0.1142 | 0.2565 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0711 | 0.0711 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0177 | 0.0177 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0177 | 0.0177 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.126 | 0.2399 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0377 | 0.0845 |
Trichomonas vaginalis | glutaminase, putative | 0.0265 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0177 | 0.0177 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0177 | 0.0177 |
Trypanosoma brucei | trypanothione reductase | 0.0126 | 0.4451 | 1 |
Onchocerca volvulus | 0.0023 | 0.0308 | 0.0255 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0377 | 0.0377 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0095 | 0.321 | 0.6112 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0032 | 0.0676 | 0.0676 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0001 | 0.0002 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0308 | 0.0615 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0177 | 0.0337 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0308 | 0.0308 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0308 | 0.0308 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0177 | 0.0337 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0033 | 0.0719 | 0.137 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0038 | 0.0083 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0044 | 0.1142 | 0.2565 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0026 | 0.0026 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0308 | 0.0234 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0044 | 0.1142 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0118 | 0.0262 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0177 | 0.0337 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0177 | 0.0177 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0308 | 0.0234 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0095 | 0.321 | 0.6112 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0377 | 0.0845 |
Brugia malayi | hypothetical protein | 0.0148 | 0.5319 | 0.5319 |
Plasmodium falciparum | thioredoxin reductase | 0.0044 | 0.1142 | 0.2565 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0177 | 0.0177 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0177 | 0.0337 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0711 | 0.0711 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0969 | 0.0969 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.1028 | 0.1028 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0033 | 0.0719 | 0.137 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0044 | 0.1142 | 0.2565 |
Plasmodium falciparum | thioredoxin reductase | 0.0126 | 0.4451 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.0001 | 0.0001 |
Toxoplasma gondii | thioredoxin reductase | 0.0126 | 0.4451 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0177 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0044 | 0.1142 | 0.2565 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0308 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0075 | 0.0075 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0118 | 0.0262 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0377 | 0.0845 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0033 | 0.0719 | 0.1614 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0308 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.321 | 0.321 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0044 | 0.1142 | 0.1142 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0044 | 0.1142 | 0.1142 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.2978 | 0.5671 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0044 | 0.1142 | 0.1037 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0177 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0308 | 0.0234 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.1028 | 0.0921 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0377 | 0.0845 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0118 | 0.0118 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0177 | 0.0337 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0118 | 0.0262 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0001 | 0.0002 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0044 | 0.1142 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0177 | 0.0177 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0177 | 0.0177 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0044 | 0.1142 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0126 | 0.4451 | 1 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0177 | 0.0177 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0044 | 0.1142 | 0.2565 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0177 | 0.0177 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0044 | 0.1142 | 0.2565 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0177 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0118 | 0.0262 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0177 | 0.0337 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0126 | 0.4451 | 0.4451 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0075 | 0.0075 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0044 | 0.1142 | 0.2565 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0044 | 0.1142 | 0.1075 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0177 | 0.0337 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0001 | 0.0001 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.1028 | 0.1957 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0177 | 0.0177 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0377 | 0.0845 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0033 | 0.0719 | 0.0719 |
Loa Loa (eye worm) | glutaminase | 0.0265 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.5319 | 0.5319 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0118 | 0.0118 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0177 | 0.0177 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0177 | 0.0177 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0177 | 0.0177 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0177 | 0.0337 |
Plasmodium vivax | glutathione reductase, putative | 0.0126 | 0.4451 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0044 | 0.1142 | 0.2565 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0033 | 0.0719 | 0.1614 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0308 | 0.069 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0308 | 0.0308 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.0001 | 0.0002 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0177 | 0.0177 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0377 | 0.0845 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0377 | 0.0377 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0177 | 0.0177 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0126 | 0.4451 | 0.8476 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0308 | 0.0615 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0969 | 0.0969 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.1323 | 0.1323 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0177 | 0.0177 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0177 | 0.0337 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0177 | 0.0177 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0118 | 0.0262 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0044 | 0.1142 | 0.2175 |
Brugia malayi | Augmenter of liver regeneration | 0.0033 | 0.0719 | 0.0719 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.1028 | 0.1028 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0001 | 0.0002 |
Plasmodium falciparum | glutathione reductase | 0.0044 | 0.1142 | 0.2565 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0177 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0095 | 0.321 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0118 | 0.0118 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0308 | 0.0234 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0118 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0177 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0126 | 0.4451 | 0.8476 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0308 | 0.0234 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0044 | 0.1142 | 0.2565 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0044 | 0.1142 | 0.1075 |
Loa Loa (eye worm) | glutathione reductase | 0.0126 | 0.4451 | 0.4451 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.1028 | 0.1957 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0177 | 0.0177 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0118 | 0.0224 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0075 | 0.0075 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0177 | 0.0337 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0177 | 0.0177 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0136 | 0.485 | 0.9236 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0044 | 0.1142 | 0.2565 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0033 | 0.0719 | 0.1614 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0308 | 0.069 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0044 | 0.1142 | 0.2565 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0308 | 0.069 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0177 | 0.0177 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.3269 | 0.3269 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.1028 | 0.1957 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0033 | 0.0719 | 0.1614 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0177 | 0.0337 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.1028 | 0.1957 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0177 | 0.0177 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0038 | 0.0083 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0044 | 0.1142 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0177 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0177 | 0.0177 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0177 | 0.0177 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0177 | 0.0337 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0177 | 0.0177 |
Leishmania major | hypothetical protein, conserved | 0.0033 | 0.0719 | 0.1614 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0033 | 0.0719 | 0.1614 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0308 | 0.0234 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0177 | 0.0177 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0177 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1028 | 0.1028 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0118 | 0.0043 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0711 | 0.0711 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0075 | 0.0167 |
Treponema pallidum | NADH oxidase | 0.0044 | 0.1142 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0177 | 0.0177 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0044 | 0.1142 | 0.2565 |
Mycobacterium ulcerans | glutaminase | 0.0265 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0377 | 0.0845 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0044 | 0.1142 | 0.2565 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0177 | 0.0177 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0095 | 0.321 | 0.321 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0308 | 0.0234 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0308 | 0.0615 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0075 | 0.0075 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0044 | 0.1142 | 0.1075 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.