Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | acetylcholinesterase | 0.0134 | 0.4031 | 1 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0268 | 0.9216 | 0.5 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0029 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0134 | 0.4031 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0134 | 0.4031 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0134 | 0.4031 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0029 | 0 | 0.5 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0134 | 0.4031 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.4031 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0134 | 0.4031 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.4031 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.0134 | 0.4031 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0134 | 0.4031 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0288 | 1 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0134 | 0.4031 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0134 | 0.4031 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Echinococcus granulosus | carboxylesterase 5A | 0.0134 | 0.4031 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 1 | Anti-inflammatory potency was measured in mice at 5 hours by modification of the Tonelli croton oil ear assay | ChEMBL. | 3625707 |
Potency (functional) | = 1.2 | Anti-inflammatory potency was measured in mice at 5 hours by modification of the croton oil ear assay | ChEMBL. | 3625707 |
Potency (functional) | = 1 | Anti-inflammatory potency was measured in mice at 5 hours by modification of the Tonelli croton oil ear assay | ChEMBL. | 3625707 |
Potency (functional) | = 1.2 | Anti-inflammatory potency was measured in mice at 5 hours by modification of the croton oil ear assay | ChEMBL. | 3625707 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.