Detailed information for compound 590540

Basic information

Technical information
  • TDR Targets ID: 590540
  • Name: N-[1-benzyl-2-[[1-benzyl-2-[2-[[1-[(1-carbamo yl-3-methylsulfanyl-propyl)carbamoyl]-2-methy l-butyl]amino]-2-oxo-ethoxy]ethyl]amino]-2-ox o-ethyl]-5-oxo-pyrrolidine-2-carboxamide
  • MW: 710.883 | Formula: C36H50N6O7S
  • H donors: 6 H acceptors: 6 LogP: 2.6 Rotable bonds: 25
    Rule of 5 violations (Lipinski): 3
  • SMILES: CSCCC(C(=O)N)NC(=O)C(C(CC)C)NC(=O)COCC(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C1CCC(=O)N1
  • InChi: 1S/C36H50N6O7S/c1-4-23(2)32(36(48)40-27(33(37)45)17-18-50-3)42-31(44)22-49-21-26(19-24-11-7-5-8-12-24)38-35(47)29(20-25-13-9-6-10-14-25)41-34(46)28-15-16-30(43)39-28/h5-14,23,26-29,32H,4,15-22H2,1-3H3,(H2,37,45)(H,38,47)(H,39,43)(H,40,48)(H,41,46)(H,42,44)
  • InChiKey: SRUUHOVCVYBSMJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[1-benzyl-2-[[1-benzyl-2-[2-[[1-[[[1-carbamoyl-3-(methylthio)propyl]amino]-oxomethyl]-2-methylbutyl]amino]-2-oxoethoxy]ethyl]amino]-2-oxoethyl]-5-oxo-2-pyrrolidinecarboxamide
  • N-[1-[[1-[2-[[1-[(1-azanyl-4-methylsulfanyl-1-oxo-butan-2-yl)amino]-3-methyl-1-oxo-pentan-2-yl]amino]-2-oxo-ethoxy]-3-phenyl-propan-2-yl]amino]-1-oxo-3-phenyl-propan-2-yl]-5-oxo-pyrrolidine-2-carboxamide
  • N-[1-benzyl-2-[[1-benzyl-2-[2-[[1-[[1-carbamoyl-3-(methylthio)propyl]carbamoyl]-2-methyl-butyl]amino]-2-keto-ethoxy]ethyl]amino]-2-keto-ethyl]-5-keto-pyrrolidine-2-carboxamide
  • N-[1-[[1-[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-3-methyl-1-oxopentan-2-yl]amino]-2-oxoethoxy]-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-5-oxopyrrolidine-2-carboxamide
  • substance P (6-11), pGlu(6)-Phe(8)-psi-(methyleneoxy)-Gly(9)-
  • N-[2-[[1-[[2-[[1-[(1-carbamoyl-3-methylsulfanyl-propyl)carbamoyl]-2-methyl-butyl]amino]-2-oxo-ethoxy]methyl]-2-phenyl-ethyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-5-oxo-pyrrolidine-2-carboxamide
  • N-[2-[[1-[[2-[[1-[[[1-carbamoyl-3-(methylthio)propyl]amino]-oxomethyl]-2-methylbutyl]amino]-2-oxoethoxy]methyl]-2-phenylethyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-5-oxo-2-pyrrolidinecarboxamide
  • N-[1-(benzyl)-2-[[1-(benzyl)-2-[2-[[1-[[1-carbamoyl-3-(methylthio)propyl]carbamoyl]-2-methyl-butyl]amino]-2-keto-ethoxy]ethyl]amino]-2-keto-ethyl]-5-keto-pyrrolidine-2-carboxamide
  • N-[1-[[1-[2-[[1-[(1-amino-4-methylsulfanyl-1-oxo-butan-2-yl)amino]-3-methyl-1-oxo-pentan-2-yl]amino]-2-oxo-ethoxy]-3-phenyl-propan-2-yl]amino]-1-oxo-3-phenyl-propan-2-yl]-5-oxo-pyrrolidine-2-carboxamide
  • 98900-29-9
  • 6-Pglu-8-phe-psi-(methyleneoxy)-9-gly-substance P (6-11)
  • L-Methioninamide, N-((2-((N-(5-oxo-L-prolyl)-L-phenylalanyl)amino)-3-phenylpropoxy)acetyl)-L-leucyl-, (S)-
  • Pglu-phe-CH2O-gly-SP (6-11)
  • Substance P (6-11), pyroglutamyl(6)-phenylalanyl(8)-psi-(methyleneoxy)-glycine(9)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0017 0.0014 0.0051
Echinococcus granulosus Excitatory amino acid transporter 0.0757 0.2788 1
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0069 0.0069
Echinococcus multilocularis muscleblind protein 0.0163 0.0561 0.0561
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.007 0.0247
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0147 0.0504 0.1805
Echinococcus granulosus phd:f box containing protein 0.0019 0.0021 0.0075
Echinococcus granulosus survival motor neuron protein 1 0.0282 0.1009 0.3617
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.0836 0.2766
Schistosoma mansoni coup transcription factor 0.0032 0.007 0.0247
Leishmania major importin beta-1 subunit, putative 0.0025 0.0047 0.0652
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.007 0.0251
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0411 0.3386
Loa Loa (eye worm) hypothetical protein 0.0032 0.007 0.0251
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.0214 0.0761
Onchocerca volvulus 0.0058 0.0167 0.0573
Schistosoma mansoni zinc finger protein 0.0015 0.0007 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0504 0.0503
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0101 0.0329 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0075
Loa Loa (eye worm) hypothetical protein 0.01 0.0327 0.1172
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0044 0.0117 0.2446
Echinococcus granulosus neutral amino acid transporter 0.0757 0.2788 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.007 0.0227
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0411 0.041
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0204 0.4693
Brugia malayi beta-lactamase family protein 0.0037 0.009 0.0322
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.009 0.0316
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0007 0.002
Echinococcus granulosus Excitatory amino acid transporter 0.0757 0.2788 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Schistosoma mansoni glutaminase 0.029 0.1038 0.3719
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0014 0.0045
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0064 0.1384
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0014 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0222 0.0789
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.007 0.0249
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.007 0.0251
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0007 0.0007
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0069 0.1549
Brugia malayi jmjC domain containing protein 0.0019 0.0021 0.0077
Schistosoma mansoni hypothetical protein 0.0032 0.007 0.0244
Brugia malayi nuclear hormone receptor 0.0015 0.0007 0.0027
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.009 0.0322
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.007 0.0251
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.007 0.0247
Brugia malayi Pre-SET motif family protein 0.0484 0.1766 0.6334
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.007 0.007
Schistosoma mansoni nuclear receptor 0.0015 0.0007 0.002
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0007 0.0027
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0032 0.007 0.0251
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.007 0.0253
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0095 0.0464
Brugia malayi beta-lactamase family protein 0.0037 0.009 0.0322
Leishmania major hypothetical protein, conserved 0.003 0.0064 0.1094
Echinococcus granulosus sodium:dicarboxylate symporter 0.0757 0.2788 1
Brugia malayi nuclear receptor NHR-67 0.0015 0.0007 0.0027
Echinococcus multilocularis neuropeptide s receptor 0.0557 0.2041 0.2041
Brugia malayi ecdysteroid receptor 0.0032 0.007 0.0253
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0095 0.2379
Brugia malayi jmjC domain containing protein 0.007 0.0214 0.0768
Schistosoma mansoni hypothetical protein 0.0068 0.0207 0.0738
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0163 0.0561 0.2012
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.017 0.059 1
Echinococcus multilocularis neuropeptide receptor A26 0.0557 0.2041 0.2041
Echinococcus multilocularis neutral amino acid transporter A 0.0757 0.2788 0.2788
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0335 0.1209 0.4331
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.007 0.0251
Echinococcus granulosus excitatory amino acid transporter 3 0.0757 0.2788 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.009 0.032
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0007 0.0027
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0335 0.1209 0.1208
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.007 0.0253
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0002 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.1258 0.6169
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.007 0.0247
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0021 0.0075
Brugia malayi hypothetical protein 0.003 0.0064 0.0229
Plasmodium vivax SET domain protein, putative 0.007 0.0214 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0117 0.0398
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.017 0.059 0.5273
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.009 0.0262
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.007 0.0253
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0504 0.1805
Echinococcus granulosus excitatory amino acid transporter 2 0.0757 0.2788 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.007 0.0251
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.009 0.032
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.007 0.0251
Echinococcus granulosus microtubule associated protein 2 0.0692 0.2546 0.913
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0007 0.0025
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0757 0.2788 0.2788
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0007 0.0027
Echinococcus multilocularis Excitatory amino acid transporter 0.0757 0.2788 0.2788
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0038 0.086
Schistosoma mansoni hypothetical protein 0.004 0.0101 0.0357
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0007 0.0027
Brugia malayi hypothetical protein 0.0015 0.0007 0.0027
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0411 0.3386
Echinococcus multilocularis protein dispatched 1 0.0047 0.0129 0.0128
Treponema pallidum fructose-bisphosphate aldolase 0.0349 0.1258 1
Entamoeba histolytica protein kinase, putative 0.0101 0.0329 0.2385
Loa Loa (eye worm) hypothetical protein 0.0042 0.0107 0.0382
Loa Loa (eye worm) hypothetical protein 0.0282 0.1009 0.3617
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0064 0.2212
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0335 0.1209 0.1208
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.007 0.007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.1258 0.6169
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.007 0.0214 0.4944
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0095 0.0464
Echinococcus multilocularis Excitatory amino acid transporter 0.0757 0.2788 0.2788
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Onchocerca volvulus 0.0034 0.008 0.026
Loa Loa (eye worm) beta-lactamase 0.0037 0.009 0.032
Schistosoma mansoni hypothetical protein 0.004 0.0101 0.0357
Echinococcus multilocularis expressed conserved protein 0.0091 0.0292 0.0292
Schistosoma mansoni patched 1 0.0042 0.0107 0.0377
Echinococcus granulosus neuropeptide s receptor 0.0557 0.2041 0.732
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.1258 0.6169
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0107 0.0382
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.007 0.0251
Loa Loa (eye worm) DR-78 0.0015 0.0007 0.0025
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0038 0.0136
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0038 0.0425
Echinococcus granulosus muscleblind protein 0.0163 0.0561 0.2012
Leishmania major hypothetical protein, conserved 0.0037 0.009 0.1755
Schistosoma mansoni hypothetical protein 0.0032 0.007 0.0244
Echinococcus multilocularis cpg binding protein 0.0036 0.0087 0.0086
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.007 0.0251
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Echinococcus multilocularis microtubule associated protein 2 0.0692 0.2546 0.2545
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0049
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0007 0.002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.007 0.007
Entamoeba histolytica hypothetical protein 0.0101 0.0329 0.2385
Schistosoma mansoni importin beta-1 0.0031 0.0069 0.0241
Loa Loa (eye worm) hypothetical protein 0.0037 0.009 0.032
Trichomonas vaginalis glutaminase, putative 0.029 0.1038 0.5056
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.007 0.0227
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.009 0.0262
Loa Loa (eye worm) hypothetical protein 0.0031 0.0069 0.0246
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0044 0.0117 0.0645
Schistosoma mansoni hypothetical protein 0.0058 0.0167 0.0593
Schistosoma mansoni jumonji domain containing protein 0.007 0.0214 0.0763
Loa Loa (eye worm) hypothetical protein 0.0044 0.0117 0.0416
Echinococcus multilocularis snurportin 1 0.0335 0.1209 0.1208
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0107 0.0382
Schistosoma mansoni hypothetical protein 0.0488 0.1781 0.6384
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.007 0.0253
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0037 0.009 0.032
Brugia malayi Importin beta-1 subunit 0.0031 0.0069 0.0248
Loa Loa (eye worm) hypothetical protein 0.0037 0.009 0.032
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.009 0.0089
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.007 0.0227
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0021 0.0021
Trichomonas vaginalis esterase, putative 0.0037 0.009 0.0262
Schistosoma mansoni ran 0.0023 0.0038 0.013
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0007 0.0027
Schistosoma mansoni hypothetical protein 0.004 0.0101 0.0357
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0069 0.1224
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.0757 0.2788 1
Schistosoma mansoni hypothetical protein 0.017 0.0588 0.2105
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.007 0.0253
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0044 0.0117 0.0412
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0326 0.1168
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.0757 0.2788 1
Schistosoma mansoni hypothetical protein 0.0032 0.007 0.0244
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0484 0.1766 0.6333
Mycobacterium ulcerans glutaminase 0.029 0.1038 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0038 0.0538
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0021 0.0021
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0326 0.1169
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0101 0.0329 0.7901
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.007 0.007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0095 0.0337
Echinococcus multilocularis excitatory amino acid transporter 3 0.0757 0.2788 0.2788
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0047 0.0045
Brugia malayi Latrophilin receptor protein 2 0.0032 0.007 0.025
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0757 0.2788 0.2788
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0002 0.0001
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0335 0.1209 0.4331
Echinococcus granulosus neutral amino acid transporter A 0.0757 0.2788 1
Brugia malayi hypothetical protein 0.0282 0.1009 0.3618
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0233 0.0831
Loa Loa (eye worm) hypothetical protein 0.0163 0.0561 0.2012
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.007 0.0247
Onchocerca volvulus 0.0037 0.009 0.0296
Schistosoma mansoni hypothetical protein 0.004 0.0101 0.0357
Echinococcus multilocularis dual specificity 0.0101 0.0329 0.0329
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0021 0.007
Brugia malayi Excitatory amino acid transporter 0.0757 0.2788 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0117 0.3095
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0038 0.2262
Loa Loa (eye worm) hypothetical protein 0.0051 0.0142 0.0507
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0064 0.1384
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0095 0.0339
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0329 0.1175
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0007 0.0025
Onchocerca volvulus 0.007 0.0214 0.0742
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.007 0.0251
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0411 0.3386
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0007 0.0025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0504 0.1801
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0101 0.0329 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0095 0.0094
Schistosoma mansoni nuclear receptor 0.0015 0.0007 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0101 0.0329 0.2385
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0049
Plasmodium vivax importin-beta 2, putative 0.0031 0.0069 0.2475
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.007 0.007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0095 0.2379
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0038 0.0134
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.007 0.0253
Echinococcus multilocularis ubiquitin specific protease 41 0.0044 0.0117 0.0116
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0504 0.1805
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.007 0.0251
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.009 0.0262
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0222 0.0789
Schistosoma mansoni thyroid hormone receptor 0.0032 0.007 0.0247
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0095 0.0018
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.007 0.0247
Echinococcus multilocularis neutral amino acid transporter A 0.0757 0.2788 0.2788
Echinococcus granulosus cpg binding protein 0.0036 0.0087 0.031
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0314 0.0314
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0038 0.0538
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0095 0.1879
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0007 0.002
Brugia malayi nuclear hormone receptor 0.0032 0.007 0.0253
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0064 0.5819
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0049
Echinococcus granulosus snurportin 1 0.0335 0.1209 0.4334
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0007 0.0025
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0411 0.1468
Brugia malayi conserved hypotetical protein 0.0015 0.0007 0.0027
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Schistosoma mansoni ap endonuclease 0.0038 0.0095 0.0333
Brugia malayi hypothetical protein 0.0017 0.0014 0.0051
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.007 0.0253
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0095 0.0051
Loa Loa (eye worm) excitatory amino acid transporter 0.0757 0.2788 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0032 0.007 0.0251
Schistosoma mansoni microtubule-associated protein tau 0.0692 0.2546 0.913
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.007 0.0069
Onchocerca volvulus Excitatory amino acid transporter homolog 0.0757 0.2788 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0504 0.1801
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0021 0.007
Brugia malayi jmjC domain containing protein 0.0019 0.0021 0.0077
Echinococcus multilocularis survival motor neuron protein 1 0.0282 0.1009 0.1008
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0029 0.0028
Loa Loa (eye worm) glutaminase 0.029 0.1038 0.3722
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0095 0.2379
Echinococcus granulosus expressed conserved protein 0.0091 0.0292 0.1046
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0044 0.0117 0.0398
Brugia malayi nuclear receptor RXR 0.0017 0.0014 0.0051
Echinococcus granulosus dnaJ subfamily B 0.0488 0.1781 0.6386
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.1258 0.6169
Schistosoma mansoni survival motor neuron protein 0.0058 0.0167 0.0593
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.007 0.0214 0.0767
Loa Loa (eye worm) hypothetical protein 0.0032 0.007 0.0249
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0021 0.0021
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0107 0.0382
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0069 0.1549
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0047 0.0045
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0044 0.0117 0.0116
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0411 0.1472
Brugia malayi Pre-SET motif family protein 0.007 0.0214 0.0767
Loa Loa (eye worm) glutaminase 2 0.029 0.1038 0.3722
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0049
Brugia malayi nuclear receptor RXR 0.0015 0.0007 0.0027
Brugia malayi nuclear receptor NHR-88 0.0015 0.0007 0.0027
Onchocerca volvulus 0.0037 0.009 0.0296
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.007 0.0247
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.008 0.0284
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0047 0.0045
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0007 0.0007
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0064 0.5819
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.0757 0.2788 1
Echinococcus granulosus excitatory amino acid transporter 2 0.0757 0.2788 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0047 0.0825
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0207 0.0744
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0349 0.1258 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.009 0.032
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0411 0.1468
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0067 0.0202 0.0721
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0007 0.0007
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.007 0.0247
Schistosoma mansoni cpg binding protein 0.0036 0.0087 0.0306
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.1258 0.6169
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0411 1
Brugia malayi CXXC zinc finger family protein 0.0034 0.008 0.0286
Echinococcus multilocularis dnaJ subfamily B 0.0488 0.1781 0.178
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0007 0.0007
Schistosoma mansoni cpg binding protein 0.0034 0.008 0.028
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.007 0.025
Echinococcus granulosus FTZ F1 alpha 0.0032 0.007 0.0251
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0007 0.0027
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0222 0.0793
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0167 0.0599
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0095 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Echinococcus granulosus ubiquitin specific protease 41 0.0044 0.0117 0.0416
Echinococcus multilocularis protein patched 0.0042 0.0107 0.0106
Echinococcus granulosus importin subunit beta 1 0.0031 0.0069 0.0246
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0117 0.3095
Echinococcus multilocularis neutral amino acid transporter A 0.0757 0.2788 0.2788
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.007 0.0249
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.007 0.007
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0101 0.0329 0.1179
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.007 0.007
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.007 0.0214 0.0761
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.007 0.0253
Brugia malayi Protein kinase domain containing protein 0.0101 0.0329 0.118
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0314 0.1127
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.007 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.01 0.0326 0.1168
Loa Loa (eye worm) hypothetical protein 0.0068 0.0207 0.0742
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0095 0.0337
Loa Loa (eye worm) hypothetical protein 0.0032 0.007 0.0251
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.009 0.2221
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0007 0.002
Echinococcus granulosus GPCR family 2 0.0032 0.007 0.0249
Onchocerca volvulus 0.0037 0.009 0.0296
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0014 0.0049
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0021 0.0075
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0007 0.0007
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0021 0.007
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.007 0.0253
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.017 0.059 0.1853
Echinococcus multilocularis excitatory amino acid transporter 2 0.0757 0.2788 0.2788
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.007 0.0251
Brugia malayi glutaminase DH11.1 0.029 0.1038 0.3723
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.009 0.0316
Onchocerca volvulus 0.0551 0.2016 0.7224
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0049
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0044 0.0117 0.0412
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.007 0.0251
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.007 0.0251
Brugia malayi jmjC domain containing protein 0.0019 0.0021 0.0077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.1258 0.6169
Schistosoma mansoni ap endonuclease 0.0038 0.0095 0.0333
Toxoplasma gondii ABC1 family protein 0.0037 0.009 0.1755
Echinococcus granulosus histone lysine methyltransferase setb 0.007 0.0214 0.0766
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.047 0.0469
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.007 0.0247
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0007 0.0025
Echinococcus granulosus geminin 0.017 0.0588 0.2109
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0021 0.0075
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0038 0.0134
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0007 0.0025
Schistosoma mansoni nuclear hormone receptor 0.0032 0.007 0.0247
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0007 0.0025
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.007 0.0251
Leishmania major GTP-binding protein, putative 0.0023 0.0038 0.0425
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0101 0.0329 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0038 0.0538
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0335 0.1209 0.4334
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0075
Entamoeba histolytica hypothetical protein 0.0025 0.0047 0.0072
Loa Loa (eye worm) hypothetical protein 0.007 0.0214 0.0766
Brugia malayi hypothetical protein 0.0019 0.0024 0.0086
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.009 0.032
Toxoplasma gondii exonuclease III APE 0.0038 0.0095 0.1879
Treponema pallidum glutamate transporter 0.0335 0.1209 0.9573
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.007 0.0253
Chlamydia trachomatis glutamate symporter 0.0757 0.2788 1
Brugia malayi CHE-14 protein 0.0042 0.0107 0.0384
Plasmodium falciparum importin beta, putative 0.0031 0.0069 0.6511
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0021 0.0075
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0064 0.1094
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.032 0.1141
Schistosoma mansoni hypothetical protein 0.0335 0.1209 0.4332
Echinococcus granulosus neutral amino acid transporter A 0.0757 0.2788 1
Echinococcus granulosus dual specificity 0.0101 0.0329 0.1179
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0326 0.1169
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.007 0.0251
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.007 0.0214 0.0213
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.1258 0.6169
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0021 0.0075
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0044 0.0117 0.0416
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.007 0.0251
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0029 0.0101
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0314 0.2263
Echinococcus multilocularis GPCR, family 2 0.0032 0.007 0.0069
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0014 0.0014
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0064 0.1384
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0095 0.0286
Loa Loa (eye worm) hypothetical protein 0.003 0.0064 0.0228
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0366 0.1322 0.1322
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.009 0.0262
Loa Loa (eye worm) hypothetical protein 0.0032 0.007 0.0251
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0117 0.3095
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0007 0.0025
Echinococcus multilocularis geminin 0.017 0.0588 0.0588
Echinococcus multilocularis lysine specific demethylase 5A 0.007 0.0214 0.0214
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0021 0.007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0044 0.0117 0.0416
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.007 0.0247
Schistosoma mansoni hypothetical protein 0.0032 0.007 0.0244
Schistosoma mansoni cpg binding protein 0.0036 0.0087 0.0306
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.007 0.0253
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0038 0.0037
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0314 0.1125
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.0214 0.0761
Schistosoma mansoni ran 0.0023 0.0038 0.013
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0095 0.0286
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0044 0.0117 0.0418
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0411 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0044 0.0117 0.0116
Loa Loa (eye worm) hypothetical protein 0.0032 0.007 0.0251
Plasmodium vivax hypothetical protein, conserved 0.0037 0.009 0.355
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.009 0.2221
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0504 0.0503
Brugia malayi RNA, U transporter 1 0.0089 0.0286 0.1026
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0021 0.0075
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.0214 0.0761
Brugia malayi hypothetical protein 0.0015 0.0007 0.0027
Brugia malayi tailless protein 0.0015 0.0007 0.0027
Brugia malayi beta-lactamase 0.0037 0.009 0.0322
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0014 0.0049
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.007 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.007 0.0253
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0007 0.0007
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0107 0.0106
Brugia malayi jmjC domain containing protein 0.0072 0.0222 0.0795
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0044 0.0117 0.0398
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0411 0.119
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0349 0.1258 1
Entamoeba histolytica protein kinase, putative 0.0101 0.0329 0.2385
Brugia malayi jmjC domain containing protein 0.0019 0.0021 0.0077
Echinococcus granulosus neuropeptide receptor A26 0.0557 0.2041 0.732
Schistosoma mansoni thyroid hormone receptor 0.0032 0.007 0.0247
Echinococcus multilocularis muscleblind protein 1 0.0163 0.0561 0.0561
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.007 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0037 0.009 0.032
Treponema pallidum glutamate/aspartate transporter 0.0335 0.1209 0.9573
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.007 0.0253
Brugia malayi steroid hormone receptor 0.0032 0.007 0.0253
Loa Loa (eye worm) hypothetical protein 0.0097 0.0314 0.1125
Brugia malayi ecdysone receptor 0.0015 0.0007 0.0027
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.007 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.007 0.0253
Onchocerca volvulus 0.0032 0.007 0.0227
Giardia lamblia Fructose-bisphosphate aldolase 0.0349 0.1258 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.007 0.0251
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.1258 0.6169
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0021 0.007
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0095 0.3801
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.009 0.0262
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0014 0.0051
Echinococcus granulosus tachykinin peptides receptor 99D 0.0366 0.1322 0.4741
Schistosoma mansoni hypothetical protein 0.017 0.0588 0.2105
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.007 0.007
Echinococcus multilocularis excitatory amino acid transporter 2 0.0757 0.2788 0.2788
Brugia malayi nuclear receptor NHR-88 0.0032 0.007 0.0253
Trichomonas vaginalis set domain proteins, putative 0.0551 0.2016 1
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.009 0.2221
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.007 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.007 0.0253
Brugia malayi Muscleblind-like protein 0.0163 0.0561 0.2014
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0044 0.0117 0.0645
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0107 0.0349
Echinococcus granulosus lysine specific demethylase 5A 0.0072 0.0222 0.0793
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.047 0.1684
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0021 0.0021
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0147 0.0504 0.1807
Loa Loa (eye worm) hypothetical protein 0.01 0.0327 0.1172
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.007 0.0251
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0504 0.1801
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0014 0.0051

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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