Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.1377 | 0.2714 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 0.3979 | 0.3979 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 0.3979 | 0.3979 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.1695 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.4656 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.1377 | 0.7399 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.4656 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.4656 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.4656 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0126 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 0.3979 | 0.3979 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.4656 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.2101 | 0.2101 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.1695 | 0.3419 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.4656 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 0.3979 | 0.7349 |
Brugia malayi | RNA binding protein | 0.0067 | 0.3979 | 0.3979 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3979 | 0.7349 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0073 | 0.4656 | 0.4656 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.4656 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 0.3979 | 0.7349 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0126 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 0.3979 | 0.3979 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.1377 | 0.2714 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3979 | 0.7349 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3979 | 0.7349 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.1695 | 0.3419 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3979 | 0.7349 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3979 | 0.7349 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.2101 | 0.2101 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1377 | 0.1377 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.1377 | 0.1377 |
Brugia malayi | Heterochromatin protein 1 | 0.0073 | 0.4656 | 0.4656 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.4656 | 1 |
Brugia malayi | TAR-binding protein | 0.0067 | 0.3979 | 0.3979 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0473 | 0.0473 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.