Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0632 | 0.2569 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0313 | 0.0622 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0734 | 0.0839 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0734 | 0.1526 |
Onchocerca volvulus | 0.0038 | 0.0734 | 1 | |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0313 | 0.0313 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0734 | 0.0839 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.001 | 0.0054 | 0.0054 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0734 | 0.0839 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0313 | 0.0313 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0202 | 0.4688 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0313 | 0.0313 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0202 | 0.4688 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0011 | 0.0081 | 0.0081 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0313 | 0.0622 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0313 | 0.0622 |
Schistosoma mansoni | nuclear receptor | 0.001 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0313 | 0.0622 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.1362 | 0.1362 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0136 | 0.0136 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0313 | 0.0622 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0081 | 0.0127 |
Loa Loa (eye worm) | endoplasmin | 0.0034 | 0.0632 | 0.1307 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0313 | 0.0313 |
Echinococcus granulosus | heat shock protein | 0.0034 | 0.0632 | 0.0632 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0034 | 0.0632 | 0.2569 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0734 | 0.0839 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0313 | 0.0622 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0034 | 0.0632 | 0.0676 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0313 | 0.0622 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.2026 | 0.4294 |
Echinococcus granulosus | endoplasmin | 0.0027 | 0.0467 | 0.0467 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0734 | 0.0899 |
Onchocerca volvulus | 0.003 | 0.0537 | 0.7104 | |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0284 | 0.0699 |
Echinococcus multilocularis | heat shock protein | 0.0034 | 0.0632 | 0.0632 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.015 | 0.3438 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0313 | 0.0622 |
Echinococcus multilocularis | smad | 0.0008 | 0.0022 | 0.0022 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0027 | 0.0467 | 0.058 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0313 | 0.0622 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0091 | 0.2014 | 0.2014 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0313 | 0.0313 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0034 | 0.0632 | 0.4675 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0734 | 0.1526 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0307 | 0.7223 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0537 | 0.0537 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0284 | 0.2243 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.4499 | 0.4499 |
Echinococcus granulosus | heat shock protein 90 | 0.0034 | 0.0632 | 0.0632 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0284 | 0.0284 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0313 | 0.0313 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0284 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0136 | 0.0243 |
Schistosoma mansoni | smad | 0.0008 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.001 | 0.0054 | 0.0067 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0734 | 0.1526 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.001 | 0.0054 | 0.0054 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0734 | 0.082 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0022 | 0.0022 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.3922 | 0.3922 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.017 | 0.0317 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0124 | 0.0218 |
Brugia malayi | nuclear receptor RXR | 0.001 | 0.0054 | 0.0067 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0022 | 0.0022 |
Schistosoma mansoni | endoplasmin | 0.0034 | 0.0632 | 0.0632 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0284 | 0.0562 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0034 | 0.0632 | 0.2569 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0313 | 0.0622 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0313 | 0.0313 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.1362 | 0.1362 |
Brugia malayi | ecdysone receptor | 0.001 | 0.0054 | 0.0067 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.1362 | 0.1362 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0284 | 0.0284 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0034 | 0.0632 | 0.4675 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0313 | 0.0622 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0121 | 0.2754 | 0.5855 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0734 | 0.082 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.001 | 0.0054 | 0.0067 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0734 | 0.5674 |
Schistosoma mansoni | nuclear receptor | 0.001 | 0.0054 | 0.0054 |
Brugia malayi | conserved hypotetical protein | 0.001 | 0.0054 | 0.0067 |
Onchocerca volvulus | 0.002 | 0.0313 | 0.3805 | |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0091 | 0.2014 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0064 | 0.1362 | 0.2871 |
Brugia malayi | MH2 domain containing protein | 0.0121 | 0.2754 | 0.5855 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0472 | 0.0472 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0734 | 0.1427 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Schistosoma mansoni | hypothetical protein | 0.0422 | 1 | 1 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0034 | 0.0632 | 0.2569 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0034 | 0.0632 | 0.2569 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0284 | 0.0184 |
Brugia malayi | Endoplasmin precursor | 0.0034 | 0.0632 | 0.1307 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Loa Loa (eye worm) | TAR-binding protein | 0.0194 | 0.4499 | 0.9594 |
Echinococcus granulosus | tar DNA binding protein | 0.0194 | 0.4499 | 0.4499 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.2003 | 0.4245 |
Schistosoma mansoni | lamin | 0.0027 | 0.0472 | 0.0472 |
Schistosoma mansoni | endoplasmin | 0.0034 | 0.0632 | 0.0632 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0734 | 0.0734 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0313 | 0.0313 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0472 | 0.0963 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0064 | 0.1362 | 0.2871 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0022 | 0.0022 |
Brugia malayi | nuclear receptor NHR-67 | 0.001 | 0.0054 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.001 | 0.0054 | 0.0054 |
Brugia malayi | tailless protein | 0.001 | 0.0054 | 0.0067 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0313 | 0.0622 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0011 | 0.0081 | 0.0081 |
Brugia malayi | Hsp90 protein | 0.0014 | 0.0154 | 0.0283 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0313 | 0.0313 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.015 | 0.3438 | 1 |
Brugia malayi | RNA binding protein | 0.0194 | 0.4499 | 0.9594 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0313 | 0.0313 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.1362 | 0.1362 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0313 | 0.0313 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0734 | 0.3119 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0313 | 0.0622 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0313 | 0.0313 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0632 | 0.2569 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0307 | 0.7223 | 1 |
Schistosoma mansoni | zinc finger protein | 0.001 | 0.0054 | 0.0054 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0313 | 0.0622 |
Echinococcus multilocularis | GPCR, family 2 | 0.0064 | 0.1362 | 0.1362 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0734 | 0.0899 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.001 | 0.0054 | 0.0054 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0022 | 0.0022 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0136 | 0.0136 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0734 | 0.1526 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0034 | 0.0632 | 0.2569 |
Loa Loa (eye worm) | RNA binding protein | 0.0194 | 0.4499 | 0.9594 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0734 | 0.0839 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0064 | 0.1362 | 0.2871 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0313 | 0.0313 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0081 | 0.0127 |
Trichomonas vaginalis | heat shock protein, putative | 0.0027 | 0.0467 | 0.0443 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0537 | 0.1104 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0307 | 0.7223 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0124 | 0.0218 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0313 | 0.0622 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0307 | 0.7223 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0307 | 0.7223 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0313 | 0.0622 |
Echinococcus multilocularis | heat shock protein 90 | 0.0027 | 0.0467 | 0.0467 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0472 | 0.0963 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.3148 | 0.67 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.1362 | 0.1362 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0472 | 0.0472 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0284 | 0.0699 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0313 | 0.0313 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0081 | 0.0127 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0284 | 0.0184 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.001 | 0.0054 | 0.0054 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.1338 | 0.1338 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.1362 | 0.1362 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0313 | 0.0622 |
Echinococcus granulosus | dual specificity | 0.0091 | 0.2014 | 0.2014 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0734 | 0.082 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.4499 | 0.4499 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0138 | 0.3148 | 0.67 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0014 | 0.0154 | 0.1477 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0313 | 0.0622 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0313 | 0.0313 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.2026 | 0.2026 |
Giardia lamblia | Grp94/Hsp90 | 0.0027 | 0.0467 | 0.0264 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0313 | 0.0313 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0284 | 0.0284 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0307 | 0.7223 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0313 | 0.0622 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0307 | 0.7223 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0313 | 0.0313 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0202 | 0.4688 | 1 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0091 | 0.2014 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0734 | 0.1526 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0313 | 0.0313 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.1176 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0307 | 0.7223 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.001 | 0.0054 | 0.0067 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0734 | 0.0734 |
Echinococcus multilocularis | tar DNA binding protein | 0.0194 | 0.4499 | 0.4499 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0307 | 0.7223 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0734 | 0.1526 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0081 | 0.0081 |
Entamoeba histolytica | hypothetical protein | 0.0091 | 0.2014 | 0.2631 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0307 | 0.7223 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0011 | 0.0081 | 0.0127 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.001 | 0.0054 | 0.0067 |
Echinococcus granulosus | heat shock protein 90 | 0.0027 | 0.0467 | 0.0467 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0014 | 0.0154 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Onchocerca volvulus | 0.0038 | 0.0734 | 1 | |
Entamoeba histolytica | heat shock protein 90, putative | 0.0034 | 0.0632 | 0.0676 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0472 | 0.0472 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0734 | 0.1526 |
Echinococcus multilocularis | endoplasmin | 0.0027 | 0.0467 | 0.0467 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0022 | 0.0022 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0014 | 0.0154 | 0.0154 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0734 | 0.082 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0313 | 0.0622 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0044 | 0.0046 |
Plasmodium vivax | endoplasmin, putative | 0.0034 | 0.0632 | 0.8239 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0022 | 0.0022 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.2003 | 0.4245 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.001 | 0.0054 | 0.0067 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.2026 | 0.4294 |
Echinococcus granulosus | geminin | 0.017 | 0.3922 | 0.3922 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0632 | 0.2569 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0734 | 0.1427 |
Entamoeba histolytica | protein kinase, putative | 0.0091 | 0.2014 | 0.2631 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0313 | 0.0313 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0422 | 1 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0734 | 0.1427 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0578 | 0.0578 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.1362 | 0.1362 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0472 | 0.0963 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0284 | 0.2722 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0313 | 0.0622 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0313 | 0.0313 |
Brugia malayi | TAR-binding protein | 0.0194 | 0.4499 | 0.9594 |
Onchocerca volvulus | 0.0038 | 0.0734 | 1 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0734 | 0.0734 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.2026 | 0.2026 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.001 | 0.0054 | 0.0054 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0313 | 0.0313 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0734 | 0.0734 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0313 | 0.0313 |
Trichomonas vaginalis | heat shock protein, putative | 0.0027 | 0.0467 | 0.0443 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0313 | 0.0622 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0034 | 0.0632 | 0.2569 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0472 | 0.0472 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0578 | 0.0578 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0313 | 0.3805 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0081 | 0.0127 |
Onchocerca volvulus | 0.0027 | 0.0472 | 0.6141 | |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0041 | 0.004 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0734 | 0.082 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.3922 | 0.3922 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0313 | 0.0622 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0632 | 0.2569 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0472 | 0.0963 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0091 | 0.2014 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0313 | 0.0622 |
Plasmodium vivax | heat shock protein 86, putative | 0.0034 | 0.0632 | 0.8239 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0284 | 0.0284 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0194 | 0.4499 | 0.9594 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0632 | 0.2569 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0313 | 0.0622 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0054 | 0.0054 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0081 | 0.0127 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.001 | 0.0054 | 0.0054 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0027 | 0.0467 | 0.1683 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.4499 | 0.4499 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0734 | 0.0839 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0027 | 0.0467 | 0.1683 |
Trichomonas vaginalis | endoplasmin, putative | 0.0021 | 0.0319 | 0.0233 |
Entamoeba histolytica | protein kinase, putative | 0.0091 | 0.2014 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0081 | 0.0127 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0091 | 0.2014 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.001 | 0.0054 | 0.0054 |
Brugia malayi | Protein kinase domain containing protein | 0.0091 | 0.2014 | 0.4269 |
Brugia malayi | Nuclear hormone receptor E75 | 0.001 | 0.0054 | 0.0067 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0734 | 0.3119 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0034 | 0.0632 | 0.1307 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0734 | 0.0839 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0734 | 0.1526 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0537 | 0.1104 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0313 | 0.0313 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.002 | 0.03 | 0.0786 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0472 | 0.0963 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.001 | 0.0054 | 0.0054 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0578 | 0.0578 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0241 | 0.5647 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.4499 | 0.4499 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0284 | 0.0699 |
Echinococcus multilocularis | heat shock protein 90 | 0.0034 | 0.0632 | 0.0632 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0313 | 0.0622 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0313 | 0.3805 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0081 | 0.0127 |
Onchocerca volvulus | 0.0027 | 0.0472 | 0.6141 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0734 | 0.3119 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0121 | 0.2754 | 0.5855 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0313 | 0.0313 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0022 | 0.0022 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0313 | 0.0622 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0472 | 0.0472 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0284 | 0.0699 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0014 | 0.0154 | 0.0283 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.001 | 0.0054 | 0.0067 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0091 | 0.2014 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0734 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0734 | 0.0839 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Trichomonas vaginalis | heat shock protein, putative | 0.0021 | 0.0319 | 0.0233 |
Treponema pallidum | heat shock protein 90 | 0.0027 | 0.0467 | 0.0264 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0027 | 0.0467 | 0.0341 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0313 | 0.0313 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0027 | 0.0467 | 0.0264 |
Schistosoma mansoni | heat shock protein | 0.0014 | 0.0154 | 0.0154 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.017 | 0.0317 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0022 | 0.0022 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0054 | 0.0054 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0027 | 0.0467 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.001 | 0.0054 | 0.0067 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Echinococcus multilocularis | dual specificity | 0.0091 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0734 | 0.1526 |
Schistosoma mansoni | heat shock protein | 0.0034 | 0.0632 | 0.0632 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0313 | 0.0622 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0632 | 0.2569 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0194 | 0.4499 | 0.9594 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0313 | 0.0313 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0011 | 0.0081 | 0.0081 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.001 | 0.0054 | 0.0054 |
Echinococcus granulosus | lamin | 0.0027 | 0.0472 | 0.0472 |
Brugia malayi | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0734 | 0.1526 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0734 | 0.1526 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0313 | 0.0622 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0313 | 0.0622 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0034 | 0.0632 | 0.2569 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0081 | 0.0127 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0054 | 0.0067 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.2026 | 0.2026 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0284 | 0.0562 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0313 | 0.0622 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0027 | 0.0467 | 0.1683 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0313 | 0.0313 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.001 | 0.0054 | 0.0054 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0313 | 0.0622 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.1362 | 0.2871 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0313 | 0.0313 |
Trichomonas vaginalis | heat shock protein, putative | 0.0027 | 0.0467 | 0.0443 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0734 | 0.082 |
Brugia malayi | hypothetical protein | 0.001 | 0.0054 | 0.0067 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0734 | 0.1427 |
Brugia malayi | nuclear receptor RXR | 0.0011 | 0.0081 | 0.0127 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0313 | 0.0622 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0022 | 0.0022 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0734 | 0.0839 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0313 | 0.0313 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.001 | 0.0054 | 0.0054 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0027 | 0.0467 | 0.0467 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0307 | 0.7223 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0307 | 0.7223 | 1 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0022 | 0.0022 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0472 | 0.0472 |
Brugia malayi | heat shock protein 90 | 0.0034 | 0.0632 | 0.1307 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0034 | 0.0632 | 0.0501 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0734 | 0.0839 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0734 | 0.1427 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.001 | 0.0054 | 0.0067 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.2026 | 0.2026 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0578 | 0.0578 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.046 | 0.0938 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0313 | 0.0622 |
Schistosoma mansoni | heat shock protein | 0.0034 | 0.0632 | 0.0632 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.1362 | 0.1362 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.4688 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0064 | 0.1362 | 0.1362 |
Plasmodium falciparum | heat shock protein 90 | 0.0034 | 0.0632 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2026 | 0.2026 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.4499 | 0.4499 |
Echinococcus granulosus | smad | 0.0008 | 0.0022 | 0.0022 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0034 | 0.0632 | 0.2569 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0081 | 0.0127 |
Plasmodium falciparum | endoplasmin, putative | 0.0021 | 0.0319 | 0.345 |
Trichomonas vaginalis | heat shock protein, putative | 0.0034 | 0.0632 | 0.0676 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0734 | 0.1526 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0734 | 0.3119 |
Loa Loa (eye worm) | DR-78 | 0.001 | 0.0054 | 0.0067 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0632 | 0.2569 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0313 | 0.0622 |
Schistosoma mansoni | lamin | 0.0027 | 0.0472 | 0.0472 |
Echinococcus multilocularis | geminin | 0.017 | 0.3922 | 0.3922 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0091 | 0.2014 | 0.4269 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0022 | 0.0022 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0632 | 0.2569 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0054 | 0.0067 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0313 | 0.0313 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2026 | 0.2026 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0632 | 0.2569 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0284 | 0.1273 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.001 | 0.0054 | 0.0054 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2026 | 0.2026 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0313 | 0.0313 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0313 | 0.3805 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0313 | 0.0622 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.015 | 0.3438 | 0.588 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -0.04 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 4.29 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 6.5 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 7 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 53 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 72 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 92 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition frequency index (IFI) (functional) | = 9.09 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
MIC (functional) | = 32 ug ml-1 | Antibacterial activity against LPS-deffective Escherichia coli OC2530 by CLSI broth microdilution method | ChEMBL. | 17908943 |
Percent growth inhibition (functional) | = 7 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 53 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 72 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 92 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
XC50 (functional) | = 6.02 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
XC50 (functional) | = 0.96126 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.