Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0012 | 0.0012 | 0.0016 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0034 | 0.0027 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0023 | 0.019 | 0.0235 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.0438 | 0.0528 |
Giardia lamblia | DINP protein human, muc B family | 0.0077 | 0.1001 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0025 | 0.021 | 0.0763 |
Loa Loa (eye worm) | carboxylesterase | 0.009 | 0.1198 | 0.1517 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0022 | 0.0012 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0077 | 0.1001 | 0.286 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0012 | 0.0022 | 0.0028 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.0109 | 0.1488 | 0.5627 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.016 | 0.2265 | 0.287 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase small chain CoxS | 0.0021 | 0.0152 | 0.0755 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0022 | 0.0174 | 0.0443 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0038 | 0.0405 | 0.51 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0034 | 0.0356 | 0.0436 |
Toxoplasma gondii | ABC1 family protein | 0.004 | 0.0438 | 0.5527 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0012 | 0.0012 | 0.0001 |
Echinococcus multilocularis | 0.0012 | 0.0022 | 0.0022 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0266 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0121 | 0.0135 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0027 | 0.0252 | 0.0312 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.002 | 0.0133 | 0.0649 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1001 | 0.286 |
Toxoplasma gondii | exonuclease III APE | 0.0015 | 0.0061 | 0.0583 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0015 | 0.0058 | 0.1136 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.004 | 0.0438 | 0.1136 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.002 | 0.0133 | 0.2678 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0438 | 0.0555 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0015 | 0.0061 | 0.5035 |
Trypanosoma brucei | unspecified product | 0.005 | 0.0586 | 0.1647 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0113 | 0.1544 | 0.4456 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0092 | 0.1237 | 0.4636 |
Leishmania major | DNA polymerase eta, putative | 0.0112 | 0.1528 | 0.44 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0022 | 0.0174 | 0.3326 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0055 | 0.0664 | 0.1874 |
Brugia malayi | nuclear hormone receptor | 0.0025 | 0.021 | 0.025 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0062 | 0.0774 | 0.0945 |
Onchocerca volvulus | 0.0024 | 0.0204 | 0.0742 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0238 | 0.3445 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0025 | 0.021 | 0.025 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0012 | 0.0012 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0438 | 0.1136 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0092 | 0.1237 | 0.7084 |
Treponema pallidum | quinoline 2-oxidoreductase | 0.0017 | 0.0099 | 0.9293 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0477 | 0.0605 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.0438 | 0.054 |
Echinococcus multilocularis | protein dispatched 1 | 0.0087 | 0.1157 | 0.1157 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0547 | 0.0547 |
Loa Loa (eye worm) | hypothetical protein | 0.0532 | 0.7892 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0532 | 0.7892 | 0.7892 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0025 | 0.021 | 0.025 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0228 | 0.4888 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0015 | 0.0061 | 0.0484 |
Brugia malayi | polk-prov protein | 0.0043 | 0.0487 | 0.0603 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0282 | 0.0343 |
Schistosoma mansoni | SET domain protein | 0.0014 | 0.0041 | 0.0036 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0025 | 0.021 | 0.0266 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0487 | 0.1359 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0025 | 0.021 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0266 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0012 | 0.0022 | 0.0028 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0081 | 0.107 | 0.1324 |
Echinococcus granulosus | neuroligin | 0.009 | 0.1198 | 0.1482 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1382 | 0.1751 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.0436 | 0.0436 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0022 | 0.0028 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.009 | 0.1198 | 0.1469 |
Brugia malayi | Carboxylesterase family protein | 0.009 | 0.1198 | 0.1504 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0025 | 0.021 | 0.025 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0013 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0517 | 0.0655 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0025 | 0.021 | 0.021 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0034 | 0.0027 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.0012 | 0.0001 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0025 | 0.021 | 0.025 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0438 | 0.1485 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0034 | 0.0344 | 0.0954 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.0012 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1082 | 0.1371 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0027 | 0.0252 | 0.0298 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0238 | 0.3445 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0022 | 0.0017 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0022 | 0.0174 | 0.0458 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0024 | 0.0204 | 0.0204 |
Schistosoma mansoni | cytochrome P450 | 0.0012 | 0.0022 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1198 | 0.1517 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0025 | 0.021 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0228 | 0.0289 |
Schistosoma mansoni | SET domain protein | 0.0027 | 0.0245 | 0.0289 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0038 | 0.0405 | 0.1134 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0012 | 0.0012 | 0.0015 |
Brugia malayi | Cytochrome P450 family protein | 0.0056 | 0.0691 | 0.0861 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.004 | 0.0438 | 0.1136 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0019 | 0.0121 | 0.015 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0025 | 0.021 | 0.0259 |
Schistosoma mansoni | nuclear hormone receptor | 0.0025 | 0.021 | 0.0245 |
Brugia malayi | Carboxylesterase family protein | 0.009 | 0.1198 | 0.1504 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0022 | 0.0012 |
Trichomonas vaginalis | esterase, putative | 0.004 | 0.0438 | 0.1485 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0113 | 0.1544 | 0.4447 |
Schistosoma mansoni | ap endonuclease | 0.0015 | 0.0061 | 0.0061 |
Onchocerca volvulus | 0.004 | 0.0438 | 0.1645 | |
Brugia malayi | Pre-SET motif family protein | 0.016 | 0.2265 | 0.2859 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0025 | 0.021 | 0.021 |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0.0092 | 0.022 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0027 | 0.0252 | 0.3083 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0025 | 0.021 | 0.0259 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0113 | 0.1544 | 0.4447 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0025 | 0.021 | 0.025 |
Brugia malayi | hypothetical protein | 0.009 | 0.1198 | 0.1504 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0023 | 0.019 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0266 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0015 | 0.0061 | 0.0106 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.004 | 0.0438 | 0.1136 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0547 | 0.0677 |
Schistosoma mansoni | acetylcholinesterase | 0.009 | 0.1198 | 0.1469 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0025 | 0.021 | 0.0259 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0015 | 0.0058 | 0.0099 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0112 | 0.1528 | 0.4409 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0278 | 0.0337 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0012 | 0.0015 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0041 | 0.0455 | 0.1278 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0547 | 0.0663 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.004 | 0.0438 | 0.0555 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0252 | 0.2287 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.009 | 0.1198 | 0.448 |
Onchocerca volvulus | 0.0029 | 0.0282 | 0.1045 | |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0034 | 0.0356 | 0.1164 |
Entamoeba histolytica | recQ family DNA helicase | 0.0012 | 0.0017 | 0.0065 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0012 | 0.0012 | 0.0015 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0043 | 0.0489 | 0.0591 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0062 | 0.0774 | 0.0958 |
Onchocerca volvulus | 0.004 | 0.0438 | 0.1645 | |
Schistosoma mansoni | coup transcription factor | 0.0025 | 0.021 | 0.0245 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0058 | 0.0074 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0013 | 0.0034 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0133 | 0.0169 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0023 | 0.019 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0034 | 0.0042 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.002 | 0.0133 | 0.0649 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0089 | 0.0097 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0015 | 0.0061 | 0.0113 |
Treponema pallidum | hypothetical protein | 0.0015 | 0.0057 | 0.4632 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.002 | 0.0133 | 0.0325 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0025 | 0.021 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0438 | 0.0555 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0015 | 0.0061 | 0.0077 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0024 | 0.0204 | 0.0238 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0093 | 0.1239 | 0.152 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0025 | 0.021 | 0.0245 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0034 | 0.0042 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0022 | 0.0174 | 0.0443 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0115 | 0.1576 | 0.1938 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.002 | 0.0133 | 0.0649 |
Plasmodium vivax | hypothetical protein, conserved | 0.004 | 0.0438 | 1 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.013 | 0.1805 | 0.2223 |
Schistosoma mansoni | gliotactin | 0.009 | 0.1198 | 0.1469 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.356 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0022 | 0.0174 | 0.0443 |
Brugia malayi | Carboxylesterase family protein | 0.0532 | 0.7892 | 1 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase small chain CoxS | 0.0021 | 0.0152 | 0.0755 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.034 | 0.034 |
Echinococcus granulosus | carboxylesterase 5A | 0.0532 | 0.7892 | 0.9766 |
Treponema pallidum | hypothetical protein | 0.0018 | 0.0105 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0532 | 0.7892 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0025 | 0.021 | 0.0245 |
Loa Loa (eye worm) | carboxylesterase | 0.0532 | 0.7892 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0013 | 0.0034 | 0.0027 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0112 | 0.1528 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1198 | 0.1517 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0115 | 0.1576 | 0.4538 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0022 | 0.0174 | 0.2062 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.002 | 0.0133 | 0.1167 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0022 | 0.0174 | 0.0458 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0092 | 0.1237 | 0.4636 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.1576 | 0.1996 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0015 | 0.0061 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0487 | 0.0617 |
Onchocerca volvulus | 0.004 | 0.0438 | 0.1645 | |
Mycobacterium ulcerans | hypothetical protein | 0.004 | 0.0438 | 0.2423 |
Loa Loa (eye worm) | hypothetical protein | 0.0532 | 0.7892 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0025 | 0.021 | 0.0266 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0252 | 0.2287 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0046 | 0.0066 |
Onchocerca volvulus | 0.0182 | 0.2598 | 1 | |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.0438 | 0.054 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0115 | 0.1576 | 0.4538 |
Schistosoma mansoni | ap endonuclease | 0.0015 | 0.0061 | 0.0061 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0092 | 0.1237 | 0.3549 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.3549 |
Echinococcus granulosus | histone lysine N methyltransferase NSD3 | 0.0027 | 0.0245 | 0.0303 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0547 | 0.0677 |
Loa Loa (eye worm) | beta-lactamase | 0.004 | 0.0438 | 0.0555 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0012 | 0.0012 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0438 | 0.0555 |
Schistosoma mansoni | thyroid hormone receptor | 0.0025 | 0.021 | 0.0245 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0025 | 0.021 | 0.0763 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.004 | 0.0438 | 0.0438 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0438 | 0.1228 |
Plasmodium vivax | SET domain protein, putative | 0.0024 | 0.0204 | 0.4543 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0092 | 0.1237 | 0.7084 |
Echinococcus granulosus | BC026374 protein S09 family | 0.009 | 0.1198 | 0.1482 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0025 | 0.021 | 0.0245 |
Brugia malayi | CHE-14 protein | 0.0082 | 0.1082 | 0.1357 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0013 | 0.0034 | 0.0027 |
Echinococcus granulosus | zinc finger protein | 0.0023 | 0.0189 | 0.0234 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0025 | 0.021 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0058 | 0.0074 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0026 | 0.0224 | 0.0591 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0015 | 0.0058 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.0438 | 0.0528 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0025 | 0.021 | 0.0245 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0092 | 0.1237 | 0.3549 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0025 | 0.021 | 0.0259 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0068 | 0.0859 | 0.1063 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0082 | 0.1082 | 0.1339 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0043 | 0.0489 | 0.0605 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0024 | 0.0204 | 0.2462 |
Leishmania major | DNA polymerase kappa, putative | 0.0022 | 0.0174 | 0.0443 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.0012 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1198 | 0.1517 |
Brugia malayi | AMP-binding enzyme family protein | 0.002 | 0.0133 | 0.0154 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.004 | 0.0438 | 0.0542 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0025 | 0.021 | 0.025 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0025 | 0.021 | 0.025 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0022 | 0.0012 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0025 | 0.021 | 0.021 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0025 | 0.021 | 0.0245 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0027 | 0.0252 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0266 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0015 | 0.0061 | 0.0062 |
Mycobacterium ulcerans | hypothetical protein | 0.002 | 0.0133 | 0.0649 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.002 | 0.0133 | 0.0649 |
Toxoplasma gondii | hypothetical protein | 0.0038 | 0.0418 | 0.5273 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.356 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.3549 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0034 | 0.0344 | 0.0939 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0025 | 0.021 | 0.0266 |
Brugia malayi | ecdysteroid receptor | 0.0025 | 0.021 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1198 | 0.1517 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.002 | 0.0133 | 0.0649 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.002 | 0.0133 | 0.1167 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0023 | 0.019 | 0.2276 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0087 | 0.1159 | 0.3322 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.002 | 0.0133 | 0.0325 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0019 | 0.0121 | 0.0121 |
Echinococcus multilocularis | histone lysine N methyltransferase NSD3 | 0.0027 | 0.0245 | 0.0245 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0164 | 0.2316 | 0.2316 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0081 | 0.107 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0022 | 0.0174 | 0.0458 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0547 | 0.0663 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1198 | 0.1517 |
Schistosoma mansoni | bromodomain containing protein | 0.0071 | 0.0919 | 0.1124 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0025 | 0.021 | 0.021 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0228 | 0.5098 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0025 | 0.021 | 0.025 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0025 | 0.021 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0058 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0025 | 0.021 | 0.0266 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.0438 | 0.1485 |
Schistosoma mansoni | zinc finger protein | 0.0012 | 0.0012 | 0.0001 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0072 | 0.0931 | 0.5297 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0012 | 0.0022 | 0.0074 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0021 | 0.0148 | 0.3241 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0025 | 0.021 | 0.0245 |
Echinococcus multilocularis | bloom syndrome protein | 0.0034 | 0.0356 | 0.0356 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0025 | 0.021 | 0.0259 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0022 | 0.0174 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0438 | 0.1485 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0228 | 0.0601 |
Echinococcus granulosus | bloom syndrome protein | 0.0034 | 0.0356 | 0.0441 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0115 | 0.1576 | 0.9058 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0015 | 0.0061 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0489 | 0.062 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0347 | 0.0415 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0022 | 0.0174 | 0.0443 |
Mycobacterium ulcerans | hypothetical protein | 0.0126 | 0.1737 | 1 |
Giardia lamblia | DNA damage repair protein | 0.0022 | 0.0174 | 0.1199 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0072 | 0.0923 | 0.117 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0532 | 0.7892 | 0.9766 |
Trypanosoma brucei | unspecified product | 0.0087 | 0.1159 | 0.3322 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.002 | 0.0133 | 0.0649 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0112 | 0.1528 | 0.44 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0072 | 0.0923 | 0.0923 |
Trypanosoma brucei | ISWI complex protein | 0.0017 | 0.0092 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1198 | 0.1517 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.034 | 0.0406 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0012 | 0.0022 | 0.0017 |
Onchocerca volvulus | 0.009 | 0.1198 | 0.4584 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.009 | 0.1198 | 0.1482 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0038 | 0.0405 | 0.1119 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0025 | 0.021 | 0.025 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0068 | 0.0859 | 0.0859 |
Echinococcus granulosus | dnaJ subfamily B | 0.0323 | 0.4724 | 0.5845 |
Schistosoma mansoni | DNA helicase recq1 | 0.0023 | 0.019 | 0.0221 |
Mycobacterium leprae | conserved hypothetical protein | 0.004 | 0.0438 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.009 | 0.1198 | 0.3215 |
Brugia malayi | Pre-SET motif family protein | 0.0024 | 0.0204 | 0.0243 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0012 | 0.0017 | 0.0006 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0131 | 0.0166 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0025 | 0.021 | 0.0245 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0126 | 0.1737 | 0.469 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0037 | 0.0394 | 0.2168 |
Schistosoma mansoni | DNA polymerase eta | 0.0112 | 0.1528 | 0.1879 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0023 | 0.019 | 0.0235 |
Echinococcus multilocularis | dna polymerase eta | 0.0112 | 0.1528 | 0.1528 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0072 | 0.0923 | 0.8615 |
Echinococcus multilocularis | protein patched | 0.0082 | 0.1082 | 0.1082 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.009 | 0.1198 | 0.448 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0072 | 0.0923 | 0.1156 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.004 | 0.0438 | 0.054 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0062 | 0.0774 | 0.0774 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0266 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0012 | 0.0012 | 0.0001 |
Brugia malayi | nuclear receptor RXR | 0.0013 | 0.0034 | 0.0027 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0323 | 0.4724 | 0.4724 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0055 | 0.0664 | 0.1874 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0022 | 0.0017 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.3549 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0072 | 0.0923 | 0.2465 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0023 | 0.019 | 0.1372 |
Mycobacterium ulcerans | beta-lactamase | 0.004 | 0.0438 | 0.2423 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0022 | 0.0174 | 0.0458 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0266 |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0.0092 | 0.022 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.006 | 0.0747 | 0.9584 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0072 | 0.0923 | 0.1129 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.034 | 0.0406 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0038 | 0.0405 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0025 | 0.021 | 0.025 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0012 | 0.0012 | 0.0012 |
Brugia malayi | beta-lactamase | 0.004 | 0.0438 | 0.054 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0252 | 0.0298 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0109 | 0.1488 | 0.5627 |
Brugia malayi | AMP-binding enzyme family protein | 0.002 | 0.0133 | 0.0154 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.009 | 0.1198 | 0.1469 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0023 | 0.019 | 0.3795 |
Brugia malayi | steroid hormone receptor | 0.0025 | 0.021 | 0.025 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0038 | 0.0405 | 0.1134 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0025 | 0.021 | 0.0266 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.009 | 0.1198 | 0.1469 |
Schistosoma mansoni | DNA helicase recq5 | 0.0023 | 0.019 | 0.0221 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.002 | 0.0133 | 0.0304 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (small chain) | 0.0021 | 0.0152 | 0.0354 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0012 | 0.0012 | 0.0012 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0438 | 0.1136 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0228 | 0.4888 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0774 | 0.0981 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0438 | 0.1136 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0487 | 0.1359 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0051 | 0.0615 | 0.3458 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.002 | 0.0133 | 0.1167 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Mycobacterium ulcerans | hypothetical protein | 0.0022 | 0.0174 | 0.0883 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0024 | 0.0204 | 0.0238 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0038 | 0.0405 | 0.1119 |
Schistosoma mansoni | hypothetical protein | 0.0283 | 0.4127 | 0.51 |
Echinococcus granulosus | expressed conserved protein | 0.0077 | 0.0995 | 0.1232 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0438 | 0.1228 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0037 | 0.0394 | 0.2168 |
Trypanosoma brucei | hypothetical protein, conserved | 0.004 | 0.0438 | 0.1214 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.034 | 0.042 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0115 | 0.1576 | 0.4547 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0121 | 0.0135 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0054 | 0.0652 | 0.2331 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.002 | 0.0133 | 0.0304 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0043 | 0.0489 | 0.0591 |
Onchocerca volvulus | 0.002 | 0.0133 | 0.0468 | |
Echinococcus multilocularis | neuroligin | 0.009 | 0.1198 | 0.1198 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0109 | 0.1488 | 0.5627 |
Leishmania major | DNA polymerase eta, putative | 0.0062 | 0.0778 | 0.221 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0025 | 0.021 | 0.021 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.004 | 0.0438 | 0.1136 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1018 | 0.1289 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0012 | 0.0022 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Mycobacterium leprae | Probable lipase LipE | 0.004 | 0.0438 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0025 | 0.021 | 0.0266 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0025 | 0.021 | 0.021 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0282 | 0.0358 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0077 | 0.1001 | 0.2678 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0012 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0283 | 0.4127 | 0.51 |
Echinococcus granulosus | dna polymerase eta | 0.0112 | 0.1528 | 0.1891 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0012 | 0.0012 | 0.0012 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0012 | 0.0022 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0438 | 0.0555 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0238 | 0.3445 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0547 | 0.0663 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0025 | 0.021 | 0.0245 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0532 | 0.7892 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0574 | 0.0727 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0022 | 0.0174 | 0.3832 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0043 | 0.0489 | 0.0489 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0347 | 0.0415 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0082 | 0.1082 | 0.1082 |
Brugia malayi | Carboxylesterase family protein | 0.009 | 0.1198 | 0.1504 |
Schistosoma mansoni | patched 1 | 0.0082 | 0.1082 | 0.1326 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0022 | 0.0169 | 0.0209 |
Onchocerca volvulus | 0.009 | 0.1198 | 0.4584 | |
Loa Loa (eye worm) | carboxylesterase | 0.009 | 0.1198 | 0.1517 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0164 | 0.2316 | 0.2866 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0032 | 0.0322 | 0.7597 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0026 | 0.0224 | 0.0644 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0046 | 0.0066 |
Schistosoma mansoni | nuclear receptor | 0.0012 | 0.0012 | 0.0001 |
Echinococcus granulosus | FTZ F1 alpha | 0.0025 | 0.021 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.1528 | 0.1936 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0013 | 0.0034 | 0.0027 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0051 | 0.0615 | 0.1622 |
Loa Loa (eye worm) | DR-78 | 0.0012 | 0.0012 | 0.0016 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0012 | 0.0012 | 0.0012 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0051 | 0.0615 | 0.3458 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0062 | 0.0778 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.009 | 0.1198 | 0.1198 |
Brugia malayi | nuclear receptor NHR-88 | 0.0025 | 0.021 | 0.025 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0081 | 0.107 | 0.107 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0438 | 0.0555 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.009 | 0.1198 | 0.1469 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0025 | 0.021 | 0.0259 |
Echinococcus multilocularis | potassium voltage gated channel subfamily A | 0.0059 | 0.0733 | 0.0733 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.002 | 0.0133 | 0.0325 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0015 | 0.0061 | 0.0077 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0022 | 0.0028 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.009 | 0.1198 | 0.1198 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0228 | 0.0273 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.0436 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0034 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1198 | 0.1517 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0015 | 0.0061 | 0.5 |
Echinococcus multilocularis | dna polymerase kappa | 0.0092 | 0.1237 | 0.1237 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0056 | 0.0691 | 0.0875 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.019 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0017 | 0.0021 |
Brugia malayi | Bromodomain containing protein | 0.0084 | 0.1114 | 0.1399 |
Trypanosoma brucei | unspecified product | 0.005 | 0.0586 | 0.1647 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.3549 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0015 | 0.0058 | 0.0211 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0544 | 0.8082 | 1 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0022 | 0.0176 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.1082 | 0.4024 |
Echinococcus multilocularis | expressed conserved protein | 0.0077 | 0.0995 | 0.0995 |
Onchocerca volvulus | 0.0025 | 0.021 | 0.0763 | |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0034 | 0.0344 | 0.0954 |
Echinococcus multilocularis | acetylcholinesterase | 0.0532 | 0.7892 | 0.7892 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0238 | 0.3445 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.356 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0015 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0034 | 0.0042 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0544 | 0.8082 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0025 | 0.021 | 0.0763 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0133 | 0.0169 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.3549 |
Mycobacterium tuberculosis | Probable hydrolase | 0.004 | 0.0438 | 0.1136 |
Mycobacterium ulcerans | hypothetical protein | 0.0018 | 0.0105 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0266 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0025 | 0.021 | 0.025 |
Brugia malayi | cytochrome P450 | 0.0012 | 0.0022 | 0.0012 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0228 | 0.0601 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.0189 | 0.0219 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.004 | 0.0438 | 0.1136 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0092 | 0.0099 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0064 | 0.0808 | 0.0987 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0072 | 0.0923 | 0.1129 |
Leishmania major | DNA damage repair protein, putative | 0.0022 | 0.0174 | 0.0443 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0025 | 0.021 | 0.025 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0015 | 0.0061 | 0.013 |
Loa Loa (eye worm) | RecQ helicase | 0.0034 | 0.0356 | 0.0451 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0027 | 0.0238 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0485 | 0.0615 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0046 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.009 | 0.1198 | 0.3215 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0347 | 0.0415 |
Brugia malayi | Telomerase reverse transcriptase | 0.01 | 0.135 | 0.1698 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0252 | 0.0304 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0026 | 0.0224 | 0.0591 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0115 | 0.1576 | 0.1576 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0092 | 0.0203 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.002 | 0.0133 | 0.2678 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.009 | 0.1198 | 0.6854 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.3549 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0012 | 0.0012 | 0.0016 |
Brugia malayi | Carboxylesterase family protein | 0.009 | 0.1198 | 0.1504 |
Schistosoma mansoni | nuclear receptor | 0.0012 | 0.0012 | 0.0001 |
Echinococcus granulosus | dna polymerase kappa | 0.0092 | 0.1237 | 0.1531 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0025 | 0.021 | 0.0245 |
Echinococcus granulosus | acetylcholinesterase | 0.0532 | 0.7892 | 0.9766 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0023 | 0.0181 | 0.0229 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0282 | 0.0335 |
Leishmania major | DNA polymerase kappa, putative | 0.0077 | 0.1001 | 0.286 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0054 | 0.0652 | 0.2331 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0022 | 0.0013 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.004 | 0.0438 | 0.1136 |
Echinococcus multilocularis | geminin | 0.0283 | 0.4127 | 0.4127 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0013 | 0.0034 | 0.0027 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0055 | 0.0664 | 0.1874 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0228 | 0.2774 |
Echinococcus granulosus | acetylcholinesterase | 0.0532 | 0.7892 | 0.9766 |
Mycobacterium ulcerans | lipase LipD | 0.004 | 0.0438 | 0.2423 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0532 | 0.7892 | 0.7892 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0547 | 0.0693 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0547 | 0.0547 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0025 | 0.021 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0058 | 0.0074 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0015 | 0.0061 | 0.1199 |
Trichomonas vaginalis | set domain proteins, putative | 0.0182 | 0.2598 | 1 |
Loa Loa (eye worm) | cytochrome P450 | 0.0012 | 0.0022 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0034 | 0.0042 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0254 | 0.3678 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0015 | 0.0061 | 0.0113 |
Schistosoma mansoni | thyroid hormone receptor | 0.0025 | 0.021 | 0.0245 |
Brugia malayi | AMP-binding enzyme family protein | 0.002 | 0.0133 | 0.0154 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.3549 |
Leishmania major | hypothetical protein, conserved | 0.004 | 0.0438 | 0.1214 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0072 | 0.0923 | 0.1143 |
Echinococcus multilocularis | zinc finger protein | 0.0023 | 0.0189 | 0.0189 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0025 | 0.021 | 0.021 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.0438 | 0.1485 |
Echinococcus granulosus | geminin | 0.0283 | 0.4127 | 0.5107 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0115 | 0.1576 | 0.195 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0038 | 0.0405 | 0.9241 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0228 | 0.0616 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0025 | 0.021 | 0.025 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0062 | 0.0774 | 0.0945 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.3549 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.356 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0027 | 0.0238 | 0.0238 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.009 | 0.1198 | 0.1482 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0025 | 0.021 | 0.0259 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0115 | 0.1576 | 0.4547 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0023 | 0.019 | 0.2276 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0013 | 0.0034 | 0.0041 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0025 | 0.021 | 0.0259 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0026 | 0.0224 | 0.0606 |
Brugia malayi | Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit | 0.0062 | 0.0774 | 0.0967 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0054 | 0.0652 | 0.2331 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0016 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0054 | 0.0652 | 0.6289 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0544 | 0.8082 | 0.8082 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0012 | 0.0012 | 0.0001 |
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.0476 | 0.0588 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0115 | 0.1576 | 0.1984 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0347 | 0.0415 |
Entamoeba histolytica | recQ family helicase, putative | 0.0026 | 0.0224 | 0.2024 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0252 | 0.2287 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0012 | 0.0012 | 0.0012 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0015 | 0.0061 | 0.013 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0181 | 0.0209 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0013 | 0.003 | 0.0023 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0228 | 0.0616 |
Onchocerca volvulus | Telomerase reverse transcriptase homolog | 0.0138 | 0.1919 | 0.7375 |
Schistosoma mansoni | zinc finger protein | 0.0017 | 0.0092 | 0.0099 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0023 | 0.019 | 0.0225 |
Onchocerca volvulus | 0.009 | 0.1198 | 0.4584 | |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0082 | 0.1082 | 0.1371 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0252 | 0.2287 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0023 | 0.019 | 0.0225 |
Onchocerca volvulus | 0.009 | 0.1198 | 0.4584 | |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0062 | 0.0778 | 0.2222 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0082 | 0.1082 | 0.1339 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.107 | 0.1356 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0058 | 0.0074 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0142 | 0.1641 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0022 | 0.0174 | 0.0443 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.009 | 0.1198 | 0.1198 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0438 | 0.0555 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0081 | 0.107 | 0.1343 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0438 | 0.1485 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0034 | 0.0356 | 0.1164 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0023 | 0.019 | 0.0241 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0027 | 0.0238 | 0.028 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0547 | 0.0678 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0062 | 0.0774 | 0.0958 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0034 | 0.0344 | 0.0954 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0012 | 0.0012 | 0.0015 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0012 | 0.0012 | 0.0015 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0032 | 0.0326 | 0.1771 |
Onchocerca volvulus | 0.009 | 0.1198 | 0.4584 | |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0025 | 0.021 | 0.025 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.009 | 0.1198 | 0.3215 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0046 | 0.0066 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (medium chain) | 0.0037 | 0.0394 | 0.1017 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.004 | 0.0438 | 0.2423 |
Schistosoma mansoni | hypothetical protein | 0.0323 | 0.4724 | 0.5839 |
Giardia lamblia | Telomerase catalytic subunit | 0.0038 | 0.0405 | 0.3661 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0133 | 0.0169 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.002 | 0.0133 | 0.0649 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0092 | 0.1237 | 0.3549 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0266 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.004 | 0.0438 | 0.2423 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -2.06 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = -1.65 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = -1.05 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 0 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 14 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 93 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 94 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition frequency index (IFI) (functional) | = 0 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
Percent growth inhibition (functional) | = -3 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 14 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 93 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 94 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
XC50 (functional) | = 6.13 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
XC50 (functional) | = 0.73411 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.