Detailed information for compound 59757

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 447.651 | Formula: C27H45NO4
  • H donors: 1 H acceptors: 1 LogP: 8.49 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCC/C=C/CCCCCCCC(=O)Nc1cc(OC)c(cc1OC)OC
  • InChi: 1S/C27H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-27(29)28-23-21-25(31-3)26(32-4)22-24(23)30-2/h12-13,21-22H,5-11,14-20H2,1-4H3,(H,28,29)/b13-12+
  • InChiKey: GOVBOZVZKBKSMK-OUKQBFOZSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Oryctolagus cuniculus Acyl-CoA:cholesterol acyltransferase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K00637 sterol O-acyltransferase [EC2.3.1.26], putative Get druggable targets OG5_133487 All targets in OG5_133487
Echinococcus multilocularis sterol O acyltransferase 1 Get druggable targets OG5_133487 All targets in OG5_133487
Echinococcus granulosus sterol O acyltransferase 1 Get druggable targets OG5_133487 All targets in OG5_133487
Schistosoma mansoni sterol O-acyltransferase 1 Get druggable targets OG5_133487 All targets in OG5_133487
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133487 All targets in OG5_133487
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133487 All targets in OG5_133487

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum diacylglycerol O-acyltransferase 1 Acyl-CoA:cholesterol acyltransferase   305 aa 278 aa 21.9 %
Neospora caninum sterol O-acyltransferase, putative Acyl-CoA:cholesterol acyltransferase   305 aa 258 aa 20.2 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0089 0.0899 0.0891
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0365 0.0356
Echinococcus granulosus tyrosine protein kinase Blk 0.0038 0.0275 0.0267
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0033 0.0024
Echinococcus multilocularis polycomb protein SCMH1 0.0104 0.1089 0.1081
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0029 0.0156 0.0147
Plasmodium falciparum plasmepsin VIII, putative 0.0021 0.0057 0.0679
Leishmania major hypothetical protein, conserved 0.0033 0.0214 0.03
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0041 0.0309 0.075
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0111 0.1168 0.116
Loa Loa (eye worm) hypothetical protein 0.0067 0.0626 0.0913
Echinococcus multilocularis mitogen activated protein kinase 11 0.0128 0.138 0.1373
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0034 0.0224 0.0327
Brugia malayi jmjC domain containing protein 0.0074 0.0722 0.1053
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0041 0.0309 0.0432
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0241 0.0351
Brugia malayi SPARC precursor 0.0038 0.0266 0.0388
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.1081 0.1074
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0021 0.0064 0.0055
Loa Loa (eye worm) hypothetical protein 0.0264 0.3063 0.4468
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0021 0.0057 0.0236
Mycobacterium tuberculosis Conserved protein 0.0019 0.0042 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0061 0.0086
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0021 0.0064 0.0055
Trypanosoma brucei ISWI complex protein 0.0033 0.0214 0.03
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0079 0.0777 0.1087
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0089 0.0899 0.1311
Plasmodium falciparum eukaryotic initiation factor 4A 0.0058 0.052 0.8725
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0046 0.0365 0.0356
Onchocerca volvulus 0.0021 0.0057 0.009
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0021 0.0057 0.0138
Echinococcus granulosus carbonic anhydrase 0.0055 0.048 0.0472
Loa Loa (eye worm) hypothetical protein 0.0021 0.0057 0.0083
Giardia lamblia Aldose reductase 0.0067 0.0632 0.1402
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0166 0.0157
Loa Loa (eye worm) Poly(ADP-ribose) glycohydrolase 0.0156 0.1727 0.2519
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.007 0.0666 0.2326
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0026 0.012 0.0111
Loa Loa (eye worm) hypothetical protein 0.0027 0.013 0.019
Brugia malayi Glycosyl hydrolases family 31 protein 0.0195 0.2209 0.3222
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0019 0.0042 0.0061
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0058 0.052 0.1263
Loa Loa (eye worm) MBOAT family protein 0.0026 0.012 0.0174
Trichomonas vaginalis aldo/keto reductase, putative 0.0067 0.0632 0.1535
Toxoplasma gondii protease inhibitor PI2 0.0038 0.0266 0.1458
Trichomonas vaginalis alpha-glucosidase, putative 0.0043 0.0335 0.0814
Schistosoma mansoni hypothetical protein 0.0021 0.0061 0.0053
Brugia malayi bZIP transcription factor family protein 0.0083 0.0827 0.1206
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1081 0.2624
Brugia malayi Variant SH3 domain containing protein 0.002 0.0046 0.0068
Echinococcus multilocularis jun protein 0.0083 0.0827 0.0819
Brugia malayi intermediate filament protein 0.0032 0.02 0.0291
Onchocerca volvulus 0.0021 0.0064 0.01
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.007 0.067 0.0662
Schistosoma mansoni unc-13 (munc13) 0.0087 0.0876 0.0869
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0026 0.012 0.0111
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0128 0.138 0.2013
Trichomonas vaginalis aldo/keto reductase, putative 0.0067 0.0632 0.1535
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0087 0.0876 0.0869
Brugia malayi jmjC domain containing protein 0.0019 0.0033 0.0048
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0021 0.0064 0.0055
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0135 0.1472 0.1465
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0594 0.1441
Brugia malayi small heat shock protein 0.0571 0.6856 1
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0055 0.048 0.0672
Onchocerca volvulus 0.0021 0.0064 0.01
Brugia malayi protein-tyrosine kinase 0.0038 0.0275 0.0401
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0027 0.013 0.0122
Loa Loa (eye worm) hypothetical protein 0.033 0.3881 0.566
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0033 0.0046
Brugia malayi Protein kinase domain containing protein 0.0089 0.0899 0.1311
Schistosoma mansoni follistatin 0.0038 0.0266 0.0258
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0027 0.013 0.019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0057 0.0049
Schistosoma mansoni methyl-cpg binding protein mbd 0.0037 0.0261 0.0253
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0241 0.397
Echinococcus multilocularis protein kinase c epsilon type 0.0341 0.4014 0.4009
Echinococcus granulosus mitogen activated protein kinase 0.0104 0.1081 0.1074
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0309 1
Entamoeba histolytica phosphofructokinase, putative 0.0237 0.2735 0.6638
Mycobacterium ulcerans hypothetical protein 0.0036 0.0241 0.075
Schistosoma mansoni lamin 0.0032 0.02 0.0191
Onchocerca volvulus 0.0067 0.0632 0.0996
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0026 0.012 0.0111
Brugia malayi MBOAT family protein 0.0026 0.012 0.0174
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.013 0.0316
Onchocerca volvulus 0.0038 0.0266 0.0419
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0026 0.012 0.0111
Echinococcus granulosus methyl CpG binding domain protein 2 0.0037 0.0261 0.0253
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0067 0.0632 0.0886
Leishmania major glycerol uptake protein, putative 0.0026 0.012 0.0167
Mycobacterium ulcerans dihydrolipoamide acetyltransferase 0.0021 0.0061 0.0085
Schistosoma mansoni zinc finger protein 0.0033 0.0214 0.0206
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0207 0.2362 0.5732
Loa Loa (eye worm) hhat protein 0.0026 0.012 0.0174
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0033 0.0024
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0153 0.1689 0.2464
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0034 0.0224 0.1213
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0309 0.0432
Trypanosoma brucei aldo/keto reductase, putative 0.0019 0.0042 0.0059
Schistosoma mansoni ap endonuclease 0.0041 0.0309 0.03
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0043 0.0335 0.0814
Toxoplasma gondii hypothetical protein 0.0026 0.012 0.0602
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0038 0.0093
Echinococcus granulosus raf serine:threonine protein kinase 0.0082 0.0809 0.0802
Onchocerca volvulus 0.0021 0.0057 0.009
Echinococcus granulosus carbonic anhydrase II 0.0055 0.048 0.0472
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0021 0.0064 0.0055
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0594 0.1441
Brugia malayi MAP kinase sur-1 0.0104 0.1081 0.1577
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0241 0.0233
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0055 0.048 0.07
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0135 0.1472 0.2062
Trypanosoma brucei cAMP-specific phosphodiesterase 0.006 0.0546 0.0765
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0081 0.0799 0.194
Trypanosoma cruzi aldo/keto reductase, putative 0.0067 0.0632 0.0886
Leishmania major mitochondrial DNA polymerase beta 0.0361 0.4265 0.5971
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0119 0.1267 0.1259
Loa Loa (eye worm) agrin synaptic family protein 0.0038 0.0266 0.0388
Echinococcus multilocularis protein patched 0.0056 0.0489 0.0481
Schistosoma mansoni sterol O-acyltransferase 1 0.0264 0.3063 0.3057
Brugia malayi hypothetical protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) hypothetical protein 0.0081 0.0799 0.1165
Trichomonas vaginalis pten, drome, putative 0.0021 0.0064 0.0154
Leishmania major hypothetical protein, conserved 0.0026 0.012 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0899 0.0891
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0058 0.052 0.1263
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0594 0.1441
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0055 0.048 0.07
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0043 0.0335 0.0489
Plasmodium falciparum plasmepsin VII 0.0021 0.0057 0.0679
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0019 0.0042 0.0571
Loa Loa (eye worm) oxidoreductase 0.0067 0.0632 0.0922
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0058 0.052 0.0728
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Onchocerca volvulus 0.0021 0.0064 0.01
Brugia malayi PHD-finger family protein 0.0054 0.0473 0.0691
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0959 0.2328
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0033 0.0024
Brugia malayi mbt repeat family protein 0.0104 0.1089 0.1588
Entamoeba histolytica diacylglycerol kinase, putative 0.0079 0.0784 0.1902
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0266 0.1458
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.006 0.0546 0.0538
Echinococcus multilocularis serine:threonine protein kinase 38 0.0089 0.0899 0.0891
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0026 0.012 0.029
Echinococcus granulosus protein kinase c epsilon type 0.0341 0.4014 0.4009
Entamoeba histolytica 1,4-alpha-glucan branching enzyme, putative 0.0057 0.0502 0.1219
Leishmania major squalene monooxygenase-like protein 0.0594 0.7142 1
Leishmania major glycerol uptake protein, putative 0.0026 0.012 0.0167
Mycobacterium tuberculosis Conserved protein 0.0036 0.0241 0.075
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0026 0.012 0.0111
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0067 0.0632 0.0922
Entamoeba histolytica poly(ADP-ribose) glycohydrolase, putative 0.0156 0.1727 0.4192
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0166 0.0157
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0546 0.1326
Echinococcus granulosus RUN 0.0043 0.0333 0.0325
Plasmodium falciparum plasmepsin IX 0.0021 0.0057 0.0679
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0266 0.0388
Echinococcus multilocularis tyrosine protein kinase Srms 0.0038 0.0275 0.0267
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0015 0.0021
Echinococcus multilocularis Niemann Pick C1 protein 0.0056 0.0489 0.0481
Entamoeba histolytica protein kinase, putative 0.0089 0.0899 0.2181
Loa Loa (eye worm) hypothetical protein 0.0104 0.1089 0.1588
Loa Loa (eye worm) TK protein kinase 0.0038 0.0275 0.0401
Echinococcus multilocularis hypothetical protein 0.0021 0.0064 0.0055
Schistosoma mansoni zinc finger protein 0.0043 0.0329 0.0321
Loa Loa (eye worm) hypothetical protein 0.0021 0.0057 0.0083
Schistosoma mansoni polycystin 1-related 0.0043 0.0333 0.0325
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1081 0.2624
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0021 0.0064 0.0055
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.07 0.0693
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0021 0.0064 0.0055
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.0038 0.0356
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0058 0.052 0.0512
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1081 0.2624
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0033 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0959 0.2328
Plasmodium falciparum aldo-keto reductase, putative 0.0019 0.0042 0.0415
Mycobacterium leprae Conserved hypothetical protein 0.0048 0.0392 0.131
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0026 0.012 0.0111
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0594 0.1441
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0241 0.0584
Loa Loa (eye worm) hypothetical protein 0.0079 0.0784 0.1143
Onchocerca volvulus 4.1 G protein, putative homolog 0.0021 0.0064 0.01
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0034 0.0224 0.1213
Onchocerca volvulus 0.0021 0.0064 0.01
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0033 0.0024
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0026 0.012 0.0111
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0366 0.0358
Trichomonas vaginalis alpha-amylase, putative 0.0128 0.1381 0.335
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0058 0.052 0.1126
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0309 0.045
Onchocerca volvulus 0.0104 0.1089 0.1715
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0079 0.0777 0.1133
Brugia malayi beta-lactamase family protein 0.0036 0.0241 0.0351
Onchocerca volvulus 0.0036 0.0241 0.0379
Treponema pallidum quinoline 2-oxidoreductase 0.0033 0.0208 0.0465
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0021 0.0057 0.0049
Loa Loa (eye worm) hypothetical protein 0.0038 0.0266 0.0388
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0546 0.1326
Echinococcus multilocularis protein kinase c iota type 0.0267 0.31 0.3094
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0033 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0241 0.0337
Onchocerca volvulus 0.0021 0.0064 0.01
Trypanosoma brucei 2-oxoglutarate dehydrogenase E2 component, putative 0.0018 0.0018 0.0025
Mycobacterium ulcerans oxidoreductase 0.0067 0.0632 0.2203
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Loa Loa (eye worm) raf kinase 0.0079 0.0784 0.1143
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0056
Echinococcus multilocularis carbonic anhydrase 0.0055 0.048 0.0472
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0799 0.1119
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0017 0.0008
Leishmania major glycerol uptake protein, putative 0.0026 0.012 0.0167
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0058 0.052 0.0728
Schistosoma mansoni hypothetical protein 0.0033 0.0214 0.0206
Brugia malayi Protein kinase domain containing protein 0.0089 0.0899 0.1311
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.013 0.1413 0.1405
Onchocerca volvulus 0.0065 0.0606 0.0955
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0064 0.0594 1
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0241 0.0337
Plasmodium falciparum cysteine repeat modular protein 1 0.0021 0.0061 0.0755
Brugia malayi Hhat protein 0.0026 0.012 0.0174
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0055 0.048 0.0472
Echinococcus multilocularis tyrosine protein kinase HCK 0.0031 0.0183 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.3723 0.3717
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0046 0.0365 0.0356
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0079 0.0777 0.0769
Plasmodium vivax 6-phosphofructokinase, putative 0.0064 0.0594 1
Trypanosoma brucei squalene monooxygenase, putative 0.0594 0.7142 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.002 0.0046 0.0068
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Plasmodium vivax aldehyde reductase, putative 0.0019 0.0042 0.0571
Onchocerca volvulus 0.0055 0.0482 0.076
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0021 0.0064 0.0055
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0029 0.0156 0.0227
Mycobacterium leprae Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB 0.0021 0.0061 0.0085
Trypanosoma cruzi glycerol uptake protein, putative 0.0026 0.012 0.0167
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0266 0.1458
Schistosoma mansoni protein tyrosine phosphatase 0.0021 0.0064 0.0055
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0067 0.0632 0.0886
Schistosoma mansoni organic anion transporter 0.0055 0.0482 0.0474
Echinococcus multilocularis aldo keto reductase 0.0067 0.0632 0.0625
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0241 0.075
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.007 0.067 0.0662
Onchocerca volvulus 0.0021 0.0064 0.01
Loa Loa (eye worm) hypothetical protein 0.0146 0.16 0.2334
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0099 0.1025 0.1017
Brugia malayi protein kinase C II. 0.0341 0.4014 0.5855
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0632 0.0625
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0018 0.0018 0.0026
Schistosoma mansoni hypothetical protein 0.0055 0.048 0.0472
Schistosoma mansoni organic anion transporter 0.0055 0.0482 0.0474
Echinococcus granulosus Rac GTPase activating protein 1 0.0079 0.0784 0.0776
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Loa Loa (eye worm) hypothetical protein 0.0141 0.1549 0.226
Entamoeba histolytica alpha-amylase family protein 0.0128 0.1381 0.335
Toxoplasma gondii ABC1 family protein 0.0036 0.0241 0.131
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0249 0.0241
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0043 0.0335 0.0814
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0026 0.012 0.0111
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0135 0.1472 0.2062
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0089 0.0899 0.0891
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0026 0.012 0.0111
Toxoplasma gondii aspartyl protease ASP1 0.0021 0.0057 0.0236
Echinococcus multilocularis N chimaerin 0.0087 0.0876 0.0868
Trypanosoma brucei glucosidase, putative 0.0043 0.0335 0.0469
Onchocerca volvulus 0.023 0.2644 0.4165
Mycobacterium tuberculosis Conserved hypothetical protein 0.019 0.2152 0.7838
Loa Loa (eye worm) aspartyl protease 6 0.0021 0.0057 0.0083
Trypanosoma brucei RNA helicase, putative 0.0114 0.1207 0.169
Loa Loa (eye worm) hypothetical protein 0.0146 0.16 0.2334
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0309 0.513
Echinococcus multilocularis tyrosine protein kinase Blk 0.0038 0.0275 0.0267
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Echinococcus granulosus unc 13 munc13 0.0087 0.0876 0.0869
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0018 0.0018 0.0025
Plasmodium falciparum plasmepsin II 0.0021 0.0057 0.0679
Schistosoma mansoni starch branching enzyme II 0.0057 0.0502 0.0494
Treponema pallidum fructose-bisphosphate aldolase 0.0349 0.4121 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) hypothetical protein 0.0036 0.0241 0.0351
Loa Loa (eye worm) MBOAT family protein 0.0026 0.012 0.0174
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Brugia malayi Bloom's syndrome protein homolog 0.0049 0.0409 0.0597
Schistosoma mansoni lamin 0.0032 0.02 0.0191
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0034 0.0224 0.0327
Loa Loa (eye worm) hypothetical protein 0.0055 0.0482 0.0703
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0021 0.0064 0.0055
Trichomonas vaginalis alpha-amylase, putative 0.0128 0.1381 0.335
Echinococcus multilocularis dnaJ subfamily C 6 0.0134 0.1455 0.1447
Schistosoma mansoni lipoxygenase 0.0121 0.1291 0.1284
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0171 0.1911 0.6944
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0089 0.0899 0.0891
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0021 0.0064 0.0055
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0026 0.012 0.0111
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0799 0.1119
Trichomonas vaginalis phosphofructokinase, putative 0.0237 0.2735 0.6638
Echinococcus granulosus jun protein 0.0083 0.0827 0.0819
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4121 1
Schistosoma mansoni carbonic anhydrase 0.0055 0.048 0.0472
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0029 0.0156 0.0147
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0033 0.0024
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0365 0.0356
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0089 0.0899 0.1311
Echinococcus multilocularis voltage gated potassium channel subunit 0.0019 0.0042 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0594 0.1441
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0017 0.0017 0.0023
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0021 0.0064 0.0055
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0128 0.138 0.1933
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0021 0.0064 0.0093
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Plasmodium falciparum plasmepsin I 0.0021 0.0057 0.0679
Trichomonas vaginalis alpha-glucosidase, putative 0.0043 0.0335 0.0814
Schistosoma mansoni jun-related protein 0.0067 0.0635 0.0627
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Echinococcus multilocularis lamin dm0 0.0032 0.02 0.0191
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0099 0.1025 0.1017
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0033 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0042 0.0102
Onchocerca volvulus 0.0021 0.0064 0.01
Leishmania major alpha glucosidase II subunit, putative 0.0043 0.0335 0.0469
Leishmania major glycerol uptake protein, putative 0.0026 0.012 0.0167
Echinococcus multilocularis mitogen activated protein kinase 14 0.0128 0.138 0.1373
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0019 0.0042 0.0147
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0026 0.012 0.1766
Onchocerca volvulus 0.0021 0.0064 0.01
Trichomonas vaginalis amylase, putative 0.0057 0.0502 0.1219
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0029 0.0156 0.0147
Loa Loa (eye worm) hypothetical protein 0.0055 0.0482 0.0703
Brugia malayi RhoGAP domain containing protein 0.0079 0.0784 0.1143
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0335 0.0469
Loa Loa (eye worm) apoptosis regulator protein 0.0099 0.1025 0.1495
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Loa Loa (eye worm) bromodomain containing protein 0.0039 0.0278 0.0405
Plasmodium vivax aspartyl protease, putative 0.0021 0.0057 0.083
Echinococcus granulosus polyADP ribose glycohydrolase 0.0156 0.1727 0.172
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0632 0.0625
Echinococcus granulosus lysosomal alpha glucosidase 0.0195 0.2209 0.2202
Trichomonas vaginalis transmembrane protein nessy, putative 0.0026 0.012 0.029
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0021 0.0057 0.0049
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.1081 0.1514
Echinococcus granulosus aldehyde reductase 0.0048 0.0392 0.0384
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0037 0.0261 0.0253
Echinococcus granulosus histone acetyltransferase MYST2 0.0119 0.1267 0.1259
Onchocerca volvulus 0.0021 0.0064 0.01
Plasmodium falciparum plasmepsin X 0.0021 0.0057 0.0679
Brugia malayi eukaryotic initiation factor 4A 0.0058 0.052 0.0759
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0067 0.0632 0.1535
Echinococcus granulosus lysine specific demethylase 5A 0.0074 0.0722 0.0714
Echinococcus granulosus hypothetical protein 0.0067 0.0632 0.0625
Trypanosoma cruzi glycerol uptake protein, putative 0.0026 0.012 0.0167
Echinococcus multilocularis aldo keto reductase 0.0067 0.0632 0.0625
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0063 0.0585 0.1285
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0081 0.0799 0.0791
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0055 0.048 0.07
Loa Loa (eye worm) protein tyrosine phosphatase 0.0021 0.0064 0.0093
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.043 0.5112 0.5108
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0309 0.045
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0482 0.0703
Echinococcus granulosus voltage gated potassium channel subunit 0.0019 0.0042 0.0033
Toxoplasma gondii aspartyl protease ASP3 0.0021 0.0057 0.0236
Schistosoma mansoni ap endonuclease 0.0041 0.0309 0.03
Schistosoma mansoni hypothetical protein 0.0079 0.0784 0.0776
Leishmania major ATP-dependent phosphofructokinase 0.0237 0.2735 0.383
Toxoplasma gondii GAF domain-containing protein 0.0019 0.0038 0.0127
Loa Loa (eye worm) hypothetical protein 0.033 0.3881 0.566
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Loa Loa (eye worm) hypothetical protein 0.0036 0.0241 0.0351
Echinococcus granulosus microsomal glutathione S transferase 3 0.0111 0.1168 0.116
Brugia malayi Protein kinase c protein 2 0.0232 0.2672 0.3897
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0021 0.0064 0.0154
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0026 0.012 0.0111
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0033 0.0048
Leishmania major prostaglandin f synthase, putative 0.0067 0.0632 0.0886
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0026 0.012 0.0174
Loa Loa (eye worm) hypothetical protein 0.0079 0.0784 0.1143
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0064 0.0594 0.1307
Brugia malayi hypothetical protein 0.0021 0.0057 0.0083
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0079 0.0777 0.1087
Echinococcus granulosus aldo keto reductase 0.0067 0.0632 0.0625
Onchocerca volvulus 0.0021 0.0064 0.01
Plasmodium falciparum plasmepsin V 0.0021 0.0057 0.0679
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0021 0.0064 0.0055
Trichomonas vaginalis alpha-glucosidase, putative 0.0043 0.0335 0.0814
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Onchocerca volvulus 0.0021 0.0064 0.01
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0419 0.4978 0.4973
Echinococcus granulosus carbonic anhydrase 0.0055 0.048 0.0472
Onchocerca volvulus 0.0043 0.0333 0.0525
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0309 0.0712
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Leishmania major eukaryotic initiation factor 4a, putative 0.0058 0.052 0.0728
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0055 0.048 0.0472
Plasmodium vivax 6-phosphofructokinase, putative 0.0064 0.0594 1
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0482 0.076
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0309 0.0432
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0078 0.0771 0.0763
Trichomonas vaginalis alpha-glucosidase, putative 0.0043 0.0335 0.0814
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0057 0.0049
Echinococcus granulosus tyrosine protein kinase Src64B 0.0046 0.0365 0.0356
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Loa Loa (eye worm) hypothetical protein 0.0079 0.0784 0.1143
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0266 0.0388
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0266 0.1458
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Trichomonas vaginalis DNA helicase recq1, putative 0.0049 0.0409 0.0993
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0266 0.1458
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0241 0.0584
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0067 0.0632 0.2203
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0455 0.1103
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0632 0.0625
Brugia malayi Cytochrome P450 family protein 0.0029 0.0164 0.0239
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0021 0.0057 0.0083
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0026 0.012 0.0111
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0079 0.0777 0.0769
Brugia malayi hypothetical protein 0.0021 0.0064 0.0093
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0033 0.0094
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0079 0.0777 0.1087
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0237 0.2735 0.383
Toxoplasma gondii aspartyl protease 0.0021 0.0057 0.0236
Echinococcus granulosus intermediate filament protein 0.0032 0.02 0.0191
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0021 0.0064 0.0055
Schistosoma mansoni atypical protein kinase C 0.0274 0.3189 0.3184
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0055 0.048 0.0672
Trypanosoma brucei glycerol uptake protein, putative 0.0026 0.012 0.0167
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0026 0.012 0.0111
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0155 0.0811
Echinococcus granulosus lamin dm0 0.0032 0.02 0.0191
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0333 0.0325
Loa Loa (eye worm) runx1 0.0066 0.0622 0.0907
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Echinococcus granulosus carbonic anhydrase 0.0055 0.048 0.0472
Onchocerca volvulus 0.0021 0.0061 0.0097
Echinococcus multilocularis carbonic anhydrase 0.0055 0.048 0.0472
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0189 0.2139 0.3119
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0021 0.0064 0.0055
Echinococcus granulosus serine:threonine protein kinase N2 0.0169 0.1888 0.1881
Toxoplasma gondii phosphofructokinase PFKII 0.0064 0.0594 0.3373
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0799 0.194
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0241 0.0351
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0098 0.1008 0.3597
Mycobacterium ulcerans 6-phosphofructokinase 0.0237 0.2735 1
Schistosoma mansoni tyrosine kinase 0.0046 0.0365 0.0356
Loa Loa (eye worm) hypothetical protein 0.0055 0.048 0.07
Brugia malayi MBOAT family protein 0.0026 0.012 0.0174
Schistosoma mansoni carbonic anhydrase-related 0.0055 0.048 0.0472
Brugia malayi Pleckstrin Homology Domain 0.0084 0.0844 0.1231
Trypanosoma cruzi GUP1, putative 0.0026 0.012 0.0167
Brugia malayi Protein-tyrosine phosphatase 1 0.0021 0.0064 0.0093
Brugia malayi 6-phosphofructokinase 0.0237 0.2735 0.3989
Toxoplasma gondii glycosyltransferase 0.0057 0.0502 0.284
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0099 0.1025 0.1017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0241 0.0351
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0249 0.0241
Echinococcus granulosus eukaryotic initiation factor 4A 0.0058 0.052 0.0512
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0027 0.013 0.0122
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.043 0.5112 0.5108
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0034 0.0224 0.0216
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Onchocerca volvulus 0.0021 0.0064 0.01
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0241 0.0584
Echinococcus multilocularis sterol regulatory element binding protein 0.0056 0.0489 0.0481
Onchocerca volvulus 0.0032 0.02 0.0314
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0799 0.1119
Onchocerca volvulus 0.0029 0.0166 0.0261
Loa Loa (eye worm) hypothetical protein 0.053 0.6347 0.9258
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0064 0.0594 1
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0021 0.0064 0.0055
Onchocerca volvulus 0.0019 0.0042 0.0066
Echinococcus granulosus protein kinase C gamma type 0.0238 0.274 0.2734
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0241 0.0584
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0043 0.0335 0.1863
Echinococcus granulosus aldo keto reductase 0.0067 0.0632 0.0625
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0099 0.1025 0.1495
Schistosoma mansoni diacylglycerol kinase theta 0.0079 0.0784 0.0776
Schistosoma mansoni bromodomain containing protein 0.0138 0.1509 0.1502
Brugia malayi aspartic protease BmAsp-1, identical 0.0021 0.0057 0.0083
Entamoeba histolytica PH domain containing protein kinase, putative 0.0174 0.1948 0.4728
Loa Loa (eye worm) MBCTL1 0.0119 0.1267 0.1848
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0021 0.0064 0.0055
Onchocerca volvulus 0.0067 0.0632 0.0996
Leishmania major glycerol uptake protein, putative 0.0026 0.012 0.0167
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0081 0.0799 0.0791
Echinococcus multilocularis carbonic anhydrase 0.0055 0.048 0.0472
Giardia lamblia Aldose reductase 0.0067 0.0632 0.1402
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0166 0.0157
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Trichomonas vaginalis set domain proteins, putative 0.0234 0.2694 0.6539
Mycobacterium leprae Possible oxidoreductase 0.0019 0.0042 0.0013
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0021 0.0064 0.0093
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4121 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0081 0.0799 0.1166
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0081 0.0799 0.0791
Brugia malayi Variant SH3 domain containing protein 0.0087 0.0876 0.1277
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0021 0.0064 0.0055
Echinococcus granulosus Diacylglycerol kinase theta 0.0079 0.0784 0.0776
Leishmania major hypothetical protein, conserved 0.0019 0.0033 0.0046
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0482 0.076
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0058 0.052 0.0512
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0021 0.0064 0.0089
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0087 0.0876 0.1277
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0021 0.0064 0.0055
Echinococcus granulosus neutral alpha glucosidase AB 0.0043 0.0335 0.0327
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0057 0.0049
Trichomonas vaginalis amylase, putative 0.0128 0.1381 0.335
Mycobacterium tuberculosis Conserved protein 0.0036 0.0241 0.075
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.006 0.0546 0.0538
Brugia malayi beta-lactamase 0.0036 0.0241 0.0351
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0626 0.0618
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.0722 0.0714
Loa Loa (eye worm) hypothetical protein 0.023 0.2644 0.3856
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0241 0.0233
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0104 0.1081 0.1514
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.004 0.029 0.0933
Loa Loa (eye worm) hypothetical protein 0.0032 0.0202 0.0294
Onchocerca volvulus 0.0225 0.2583 0.407
Brugia malayi Protein kinase domain containing protein 0.0018 0.0023 0.0034
Brugia malayi NADH-dependent xylose reductase 0.0019 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.0048
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0067 0.0632 0.1535
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0057 0.0049
Trichomonas vaginalis protein kinase inhibitor, putative 0.0134 0.1455 0.353
Plasmodium vivax aspartyl protease, putative 0.0021 0.0057 0.083
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0137 0.1497 0.541
Trypanosoma brucei carbonic anhydrase-like protein 0.0055 0.048 0.0672
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Trypanosoma cruzi glycerol uptake protein, putative 0.0026 0.012 0.0167
Trypanosoma cruzi squalene monooxygenase, putative 0.0594 0.7142 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0067 0.0632 0.0922
Entamoeba histolytica recQ family DNA helicase 0.0017 0.0017 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0015 0.0021
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0021 0.0064 0.0055
Trichomonas vaginalis alpha-glucosidase, putative 0.0043 0.0335 0.0814
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0019 0.0042 0.0102
Echinococcus granulosus 6 phosphofructokinase 0.0237 0.2735 0.2729
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0021 0.0064 0.0154
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0135 0.1472 0.1465
Echinococcus multilocularis musashi 0.0032 0.02 0.0191
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0083 0.0831 0.0823
Loa Loa (eye worm) 6-phosphofructokinase 0.0237 0.2735 0.3989
Plasmodium vivax aspartyl proteinase, putative 0.0021 0.0057 0.083
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0104 0.1081 0.1514
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0043 0.0335 0.0814
Loa Loa (eye worm) hypothetical protein 0.033 0.3881 0.566
Entamoeba histolytica protein kinase, putative 0.0094 0.0959 0.2328
Brugia malayi mbt repeat family protein 0.0104 0.1089 0.1588
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Onchocerca volvulus 0.0036 0.0241 0.0379
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0241 0.0233
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0055 0.048 0.07
Loa Loa (eye worm) hypothetical protein 0.0026 0.012 0.0174
Echinococcus multilocularis RUN 0.0043 0.0333 0.0325
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0361 0.4265 0.5971
Echinococcus granulosus lamin 0.0032 0.02 0.0191
Loa Loa (eye worm) hypothetical protein 0.0043 0.0333 0.0486
Plasmodium vivax aspartyl proteinase, putative 0.0021 0.0057 0.083
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.0087 0.0127
Toxoplasma gondii aldose reductase, putative 0.0067 0.0632 0.36
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0021 0.0064 0.0055
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0078 0.0771 0.0763
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0058 0.052 0.1263
Schistosoma mansoni alpha-glucosidase 0.0168 0.1874 0.1867
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0021 0.0057 0.0083
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0057 0.0049
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0034 0.0224 0.3581
Echinococcus multilocularis lysine specific demethylase 5A 0.007 0.067 0.0662
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0021 0.0064 0.0093
Toxoplasma gondii diacylglycerol kinase, putative 0.0079 0.0784 0.4484
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0229 0.263 0.3836
Schistosoma mansoni methyl-cpg binding protein mbd 0.0037 0.0261 0.0253
Loa Loa (eye worm) hypothetical protein 0.0055 0.048 0.07
Schistosoma mansoni hypothetical protein 0.0114 0.1207 0.12
Loa Loa (eye worm) 6-phosphofructokinase 0.0237 0.2735 0.3989
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0046 0.0365 0.0356
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0722 0.1053
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0104 0.1089 0.1081
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Loa Loa (eye worm) hypothetical protein 0.0089 0.0901 0.1314
Schistosoma mansoni protein kinase C mu 0.0229 0.263 0.2624
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.012 0.029
Mycobacterium tuberculosis Conserved protein 0.0036 0.0241 0.075
Echinococcus multilocularis serine threonine protein kinase 0.0238 0.274 0.2734
Giardia lamblia Sgs1 DNA helicase, putative 0.0034 0.0224 0.0396
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0241 0.0337
Treponema pallidum hypothetical protein 0.0028 0.0144 0.031
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0063 0.0585 0.142
Brugia malayi Protein kinase domain containing protein 0.0023 0.0087 0.0127
Echinococcus granulosus o acyltransferase membrane bound domain 0.0026 0.012 0.0111
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0046 0.0371 0.6132
Echinococcus multilocularis protein dispatched 1 0.0056 0.0489 0.0481
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0632 0.0625
Onchocerca volvulus 0.0055 0.0482 0.076
Schistosoma mansoni rab6-interacting 0.0043 0.0333 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0489 0.1187
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0057 0.0049
Brugia malayi MBOAT family protein 0.0026 0.012 0.0174
Brugia malayi Doublecortin family protein 0.0043 0.0333 0.0486
Brugia malayi Glycosyl hydrolases family 31 protein 0.0043 0.0335 0.0489
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0333 0.0325
Plasmodium vivax plasmepsin V, putative 0.0021 0.0057 0.083
Loa Loa (eye worm) hypothetical protein 0.0055 0.0482 0.0703
Loa Loa (eye worm) hypothetical protein 0.0409 0.4863 0.7093
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0067 0.0626 0.0618
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Schistosoma mansoni hypothetical protein 0.0641 0.7731 0.7729
Loa Loa (eye worm) hypothetical protein 0.0084 0.0837 0.122
Schistosoma mansoni intermediate filament proteins 0.0032 0.02 0.0191
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Schistosoma mansoni rab6-interacting 0.0043 0.0333 0.0325
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0229 0.263 0.3836
Loa Loa (eye worm) hypothetical protein 0.0079 0.0784 0.1143
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0058 0.052 0.0512
Loa Loa (eye worm) hypothetical protein 0.0079 0.0784 0.1143
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0166 0.0871
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0064 0.0594 0.1441
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0026 0.012 0.19
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0309 0.0749
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Trichomonas vaginalis phosphofructokinase, putative 0.0237 0.2735 0.6638
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0241 0.075
Loa Loa (eye worm) hypothetical protein 0.0093 0.0952 0.1389
Trichomonas vaginalis phosphofructokinase, putative 0.0237 0.2735 0.6638
Schistosoma mansoni DNA helicase recq1 0.0034 0.0224 0.0216
Echinococcus granulosus tyrosine kinase 0.0038 0.0275 0.0267
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0275 0.0267
Onchocerca volvulus 0.0021 0.0064 0.01
Trypanosoma brucei cAMP-specific phosphodiesterase 0.006 0.0546 0.0765
Brugia malayi diacylglycerol kinase 0.0079 0.0784 0.1143
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0021 0.0057 0.0236
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0058 0.052 0.1787
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0033 0.0048
Echinococcus multilocularis lysosomal alpha glucosidase 0.0195 0.2209 0.2202
Entamoeba histolytica alpha-amylase family protein 0.0128 0.1381 0.335
Brugia malayi hypothetical protein 0.0021 0.0057 0.0083
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0365 0.0356
Brugia malayi protein kinase C3,putative 0.0182 0.2049 0.2989
Trypanosoma brucei rac serine-threonine kinase, putative 0.0094 0.0959 0.1343
Entamoeba histolytica hypothetical protein 0.0079 0.0784 0.1902
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0959 0.2328
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.1089 0.1081
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0241 0.0233
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0171 0.1911 0.6944
Loa Loa (eye worm) hypothetical protein 0.0084 0.0844 0.1231
Schistosoma mansoni hypothetical protein 0.0099 0.1025 0.1017
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Entamoeba histolytica protein kinase, putative 0.0089 0.0899 0.2181
Loa Loa (eye worm) SRC-1 0.0046 0.0365 0.0532
Echinococcus multilocularis mitogen activated protein kinase 11 0.0128 0.138 0.1373
Echinococcus multilocularis mitogen activated protein kinase 0.0104 0.1081 0.1074
Schistosoma mansoni patched 1 0.0056 0.0489 0.0481
Onchocerca volvulus 0.0043 0.0333 0.0525
Echinococcus multilocularis zinc finger protein 0.0043 0.0329 0.0321
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0067 0.0632 0.1535
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0067 0.0632 0.0922
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Giardia lamblia Fructose-bisphosphate aldolase 0.0349 0.4121 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Schistosoma mansoni alpha glucosidase 0.0043 0.0335 0.0327
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.0042 0.0102
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Brugia malayi diacylglycerol acyltransferase 0.0026 0.012 0.0174
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0046 0.0365 0.0356
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) hypothetical protein 0.0038 0.0266 0.0388
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0057 0.0049
Onchocerca volvulus 0.0146 0.16 0.2521
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.006 0.0546 0.0538
Schistosoma mansoni protein tyrosine phosphatase 0.0021 0.0064 0.0055
Loa Loa (eye worm) hypothetical protein 0.0055 0.0482 0.0703
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0057 0.0049
Treponema pallidum alginate O-acetylation protein (algI) 0.0026 0.012 0.0251
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0029 0.0156 0.0147
Brugia malayi hypothetical protein 0.0021 0.0064 0.0093
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0021 0.0064 0.0055
Echinococcus multilocularis agrin 0.0038 0.0266 0.0258
Brugia malayi Bromodomain containing protein 0.0084 0.0835 0.1218
Brugia malayi prostaglandin transporter 0.0055 0.0482 0.0703
Leishmania major hypothetical protein, conserved 0.0021 0.0061 0.0086
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4121 1
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0026 0.012 0.0111
Brugia malayi hypothetical protein 0.0055 0.0482 0.0703
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Onchocerca volvulus 0.053 0.6347 1
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0899 0.2181
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0632 0.0625
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.1081 0.1514
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0135 0.1472 0.2147
Schistosoma mansoni vav2 0.0092 0.0936 0.0929
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0098 0.1008 0.3597
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0361 0.4265 0.5971
Echinococcus granulosus protein kinase c eta type 0.0079 0.0784 0.0776
Echinococcus granulosus RNA directed DNA polymerase 0.0141 0.1549 0.1542
Trichomonas vaginalis maltase-glucoamylase, putative 0.0043 0.0335 0.0814
Toxoplasma gondii aldo-keto reductase 0.0019 0.0042 0.0147
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0333 0.5476
Onchocerca volvulus 0.0021 0.0064 0.01
Schistosoma mansoni hypothetical protein 0.0043 0.0333 0.0325
Onchocerca volvulus 0.0067 0.0632 0.0996
Echinococcus multilocularis myotubularin protein 13 0.0084 0.0844 0.0837
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0135 0.1472 0.2062
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0081 0.0799 0.1119
Brugia malayi C1-like domain containing protein 0.0229 0.263 0.3836
Brugia malayi hypothetical protein 0.0055 0.0482 0.0703
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0034 0.0224 0.0216
Loa Loa (eye worm) hypothetical protein 0.0026 0.012 0.0174
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0959 0.2328
Trichomonas vaginalis porcupine, putative 0.0026 0.012 0.029
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1081 0.2624
Schistosoma mansoni apoptosis regulator bax 0.0099 0.1025 0.1017
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Echinococcus multilocularis ubiquitin specific protease 41 0.0081 0.0799 0.0791
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.013 0.019
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0152 0.0144
Loa Loa (eye worm) hypothetical protein 0.0225 0.2583 0.3768
Trypanosoma brucei prostaglandin f synthase 0.0067 0.0632 0.0886
Echinococcus granulosus sterol O acyltransferase 1 0.0264 0.3063 0.3057
Echinococcus multilocularis 0.0021 0.0064 0.0055
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.02 0.0291
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0309 0.0432
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0064 0.0594 0.1441
Loa Loa (eye worm) hypothetical protein 0.0055 0.048 0.07
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0037 0.0262 0.0367
Loa Loa (eye worm) beta-lactamase 0.0036 0.0241 0.0351
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0021 0.0064 0.0055
Entamoeba histolytica hypothetical protein 0.0069 0.0659 0.1599
Plasmodium vivax RNA helicase-1, putative 0.0058 0.052 0.8745
Loa Loa (eye worm) hypothetical protein 0.0081 0.0799 0.1166
Loa Loa (eye worm) hypothetical protein 0.0099 0.1025 0.1495
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0021 0.0064 0.0093
Onchocerca volvulus 0.0087 0.0876 0.1381
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0333 0.0325
Echinococcus granulosus Niemann Pick C1 protein 0.0056 0.0489 0.0481
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0333 0.0325
Schistosoma mansoni protein kinase C mu 0.0079 0.0784 0.0776
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4121 1
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0021 0.0064 0.0089
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0309 0.1002
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0058 0.052 0.1263
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0119 0.1267 0.1848
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0241 0.075
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0021 0.0064 0.0093
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0056 0.0489 0.0481
Schistosoma mansoni myelin transcription factor 1 myt1 0.0119 0.1267 0.1259
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0959 0.2328
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0019 0.0042 0.0147
Entamoeba histolytica aldose reductase, putative 0.0067 0.0632 0.1535
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0128 0.138 0.1933
Echinococcus granulosus protein kinase c iota type 0.0267 0.31 0.3094
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0546 0.1326
Leishmania major 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0018 0.0018 0.0025
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0081 0.0799 0.1813
Plasmodium falciparum plasmepsin VI 0.0021 0.0057 0.0679
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.2343 0.3418
Loa Loa (eye worm) hypothetical protein 0.0026 0.012 0.0174
Trypanosoma brucei glycerol uptake protein, putative 0.0026 0.012 0.0167
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0365 0.0356
Toxoplasma gondii hypothetical protein 0.0019 0.0038 0.0127
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0089 0.0899 0.1311
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0429 0.06
Echinococcus multilocularis carbonic anhydrase II 0.0055 0.048 0.0472
Echinococcus granulosus tissue type plasminogen activator 0.0021 0.0061 0.0053
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0546 0.0765
Schistosoma mansoni unc-13 (munc13) 0.0089 0.09 0.0892
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0546 0.1326
Plasmodium falciparum plasmepsin IV 0.0021 0.0057 0.0679
Echinococcus granulosus protein tyrosine phosphatase n9 0.0021 0.0064 0.0055
Trypanosoma cruzi poly(ADP-ribose) glycohydrolase, putative 0.0156 0.1727 0.2419
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0241 0.075
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0017 0.0017 0.0023
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0033 0.0046
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0241 0.075
Toxoplasma gondii kringle domain-containing protein 0.0021 0.0061 0.0262
Echinococcus multilocularis sterol O acyltransferase 1 0.0264 0.3063 0.3057
Loa Loa (eye worm) hypothetical protein 0.0032 0.02 0.0291
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Mycobacterium tuberculosis DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase 0.0021 0.0061 0.0085
Brugia malayi DnaJ domain containing protein 0.0134 0.1455 0.2122
Echinococcus multilocularis histone acetyltransferase MYST2 0.0119 0.1267 0.1259
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.0048
Onchocerca volvulus 0.0021 0.0064 0.01
Mycobacterium tuberculosis 1,4-alpha-glucan branching enzyme GlgB (glycogen branching enzyme) 0.0057 0.0502 0.1721
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Echinococcus multilocularis poly(ADP ribose) glycohydrolase 0.0156 0.1727 0.172
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0037 0.0262 0.0367
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0482 0.0703
Schistosoma mansoni diacylglycerol kinase theta 0.0079 0.0784 0.0776
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0104 0.1081 0.1577
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0799 0.194
Loa Loa (eye worm) hypothetical protein 0.0087 0.0876 0.1278
Echinococcus granulosus follistatin 0.0038 0.0266 0.0258
Brugia malayi Pre-SET motif family protein 0.0029 0.0166 0.0242
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.0827 0.0819
Schistosoma mansoni hypothetical protein 0.0026 0.012 0.0111
Onchocerca volvulus 0.0055 0.0482 0.076
Loa Loa (eye worm) hypothetical protein 0.0221 0.2532 0.3693
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0087 0.0876 0.0868
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0021 0.0064 0.0089
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.004 0.029 0.0933
Schistosoma mansoni alpha-glucosidase 0.0168 0.1874 0.1867
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0309 0.1002
Trichomonas vaginalis esterase, putative 0.0036 0.0241 0.0584
Mycobacterium ulcerans hypothetical protein 0.019 0.2152 0.7838
Onchocerca volvulus 0.033 0.3881 0.6114
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0309 0.03
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0064 0.0594 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Onchocerca volvulus 0.0055 0.0482 0.076
Toxoplasma gondii hypothetical protein 0.0053 0.0455 0.2561
Echinococcus granulosus phd:f box containing protein 0.0019 0.0033 0.0024
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0135 0.1472 0.5317
Treponema pallidum ATP-dependent RNA helicase 0.0058 0.052 0.1227
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0026 0.012 0.0602
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0087 0.0876 0.0869
Onchocerca volvulus 0.0067 0.0632 0.0996
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.013 0.1413 0.1405
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Brugia malayi 1,4-alpha-glucan branching enzyme 0.0057 0.0502 0.0733
Echinococcus multilocularis neutral alpha glucosidase AB 0.0043 0.0335 0.0327
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0055 0.0482 0.0474
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0055 0.048 0.07
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.0042 0.0102
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0141 0.1549 0.1542
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0037 0.0262 0.0367
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.013 0.0316
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0831 0.0823
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0594 0.1441
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0079 0.0777 0.1885
Trichomonas vaginalis aldo/keto reductase, putative 0.0067 0.0632 0.1535
Loa Loa (eye worm) hypothetical protein 0.0419 0.4978 0.7261
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Loa Loa (eye worm) oxidoreductase 0.0067 0.0632 0.0922
Loa Loa (eye worm) hypothetical protein 0.0571 0.6856 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0084 0.0076
Loa Loa (eye worm) carbonic anhydrase 3 0.0055 0.048 0.07
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.007 0.0666 0.2326
Leishmania major tyrosine specific protein phosphatase, putative 0.0021 0.0064 0.0089
Echinococcus multilocularis serine:threonine protein kinase N2 0.0254 0.2938 0.2933
Schistosoma mansoni hypothetical protein 0.0099 0.1025 0.1017
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0365 0.0356
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0021 0.0064 0.0089
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0482 0.076
Echinococcus multilocularis follistatin 0.0038 0.0266 0.0258
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0241 0.075
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.006 0.0546 0.1326
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0799 0.194
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0049 0.041 0.0401
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0317 0.3723 0.3717
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0019 0.0042 0.0061
Echinococcus granulosus Solute carrier organic anion transporter family 0.0055 0.0482 0.0474
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0081 0.0799 0.0791
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0033 0.0024
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0064 0.0594 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Mycobacterium ulcerans glycogen branching protein 0.0057 0.0502 0.1721
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0021 0.0064 0.0055
Brugia malayi MBOAT family protein 0.0026 0.012 0.0174
Schistosoma mansoni DNA helicase recq5 0.0034 0.0224 0.0216
Loa Loa (eye worm) hypothetical protein 0.0055 0.0482 0.0703
Entamoeba histolytica aldose reductase, putative 0.0067 0.0632 0.1535
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0455 0.1103
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0089 0.0899 0.0891
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0349 0.4121 1
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0079 0.0784 0.1143
Schistosoma mansoni protein tyrosine phosphatase 0.0021 0.0064 0.0055
Toxoplasma gondii 1,4-alpha-glucan-branching enzyme 0.0057 0.0502 0.284
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0058 0.052 0.2944
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0033 0.0094
Mycobacterium tuberculosis Probable oxidoreductase 0.0067 0.0632 0.2203
Loa Loa (eye worm) oxidoreductase 0.0067 0.0632 0.0922
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0099 0.1025 0.1017
Schistosoma mansoni hypothetical protein 0.0045 0.0358 0.035
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0207 0.2362 0.5732
Brugia malayi Protein kinase domain containing protein 0.0083 0.0831 0.1211
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4121 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0021 0.0064 0.0055
Entamoeba histolytica alcohol dehydrogenase, putative 0.0019 0.0042 0.0102
Brugia malayi Ras association domain family 1 isoform A 0.0079 0.0784 0.1143
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0021 0.0064 0.0055
Brugia malayi P38 map kinase family protein 2 0.0128 0.138 0.2013
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0429 0.06
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0098 0.1008 0.3597
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0309 0.0749
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Loa Loa (eye worm) DnaJ domain-containing protein 0.0134 0.1455 0.2122
Trypanosoma cruzi MFS transporter, putative 0.0055 0.0482 0.0675
Loa Loa (eye worm) RecQ helicase 0.0049 0.0409 0.0597
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0241 0.075
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0033 0.0258
Onchocerca volvulus 0.0021 0.0064 0.01
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0026 0.012 0.0602
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0366 0.0358
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0959 0.2328
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Trypanosoma brucei aldo-keto reductase, putative 0.0067 0.0632 0.0886
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0026 0.012 0.029
Loa Loa (eye worm) hypothetical protein 0.0058 0.052 0.0759
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0018 0.0018 0.001
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0632 0.0625
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0034 0.0224 0.0327
Brugia malayi jmjC domain containing protein 0.0019 0.0033 0.0048
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0026 0.012 0.0174
Schistosoma mansoni blooms syndrome DNA helicase 0.0032 0.0194 0.0185
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0046 0.0365 0.0356
Echinococcus granulosus polycomb protein SCMH1 0.0104 0.1089 0.1081
Loa Loa (eye worm) RasGEF domain-containing protein 0.0079 0.0784 0.1143
Schistosoma mansoni zinc finger protein 0.0026 0.012 0.0111
Leishmania major eukaryotic initiation factor 4a, putative 0.0058 0.052 0.0728
Onchocerca volvulus 0.0021 0.0064 0.01
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0087 0.0876 0.0868
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0058 0.052 0.0728
Loa Loa (eye worm) hypothetical protein 0.0119 0.1267 0.1848
Brugia malayi aspartic protease BmAsp-2, identical 0.0021 0.0057 0.0083
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0079 0.0784 0.1143
Echinococcus granulosus fetal alzheimer antigen falz 0.0049 0.041 0.0401
Brugia malayi hypothetical protein 0.0043 0.0333 0.0486
Toxoplasma gondii poly(ADP-ribose) glycohydrolase 0.0069 0.0659 0.3755
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0021 0.0061 0.0905
Loa Loa (eye worm) hypothetical protein 0.0036 0.0241 0.0351
Echinococcus granulosus mitogen activated protein kinase 3 0.0104 0.1081 0.1074
Toxoplasma gondii poly(ADP-ribose) glycohydrolase 0.0156 0.1727 1
Brugia malayi RhoGEF domain containing protein 0.0079 0.0784 0.1143
Brugia malayi phosphofructokinase 0.0237 0.2735 0.3989
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Trichomonas vaginalis alpha-amylase, putative 0.0128 0.1381 0.335
Schistosoma mansoni pol-related 0.0067 0.0632 0.0625
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0632 0.0625
Brugia malayi hypothetical protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) hypothetical protein 0.0036 0.0241 0.0351
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0482 0.0703
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.006 0.0546 0.1326
Brugia malayi Poly 0.0156 0.1727 0.2519
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0046 0.0365 0.0356
Mycobacterium ulcerans beta-lactamase 0.0036 0.0241 0.075
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0349 0.4121 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0029 0.0156 0.0147
Echinococcus multilocularis raf serine:threonine protein kinase 0.0082 0.0809 0.0802
Loa Loa (eye worm) hypothetical protein 0.0021 0.0057 0.0083
Toxoplasma gondii AGC kinase 0.0089 0.0899 0.5156
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0033 0.0024
Brugia malayi p70 ribosomal S6 kinase beta 0.0089 0.0899 0.1311
Echinococcus multilocularis mitogen activated protein kinase 3 0.0104 0.1081 0.1074
Echinococcus multilocularis lysosomal alpha glucosidase 0.0195 0.2209 0.2202
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Brugia malayi Bromodomain containing protein 0.0164 0.1826 0.2663
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4121 1
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0237 0.2735 1
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0055 0.0482 0.0474
Echinococcus granulosus agrin 0.0038 0.0266 0.0258
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0089 0.0899 0.0891
Schistosoma mansoni lozenge 0.0066 0.0622 0.0614
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0626 0.0618
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0309 0.0749
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0019 0.0042 0.0033
Brugia malayi SRC-1 0.0046 0.0365 0.0532
Brugia malayi Protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0632 0.0625
Mycobacterium ulcerans hypothetical protein 0.0034 0.0217 0.0663
Echinococcus multilocularis aldo keto reductase 0.0067 0.0632 0.0625
Schistosoma mansoni protein kinase C 0.0087 0.0876 0.0869
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0026 0.012 0.0111
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.043 0.5112 0.5108
Echinococcus granulosus zinc finger protein 0.0043 0.0329 0.0321
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0632 0.0625
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0266 0.0388
Loa Loa (eye worm) oxidoreductase 0.0067 0.0632 0.0922
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0043 0.0335 0.0814
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0899 0.0891
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0419 0.4978 0.4973
Schistosoma mansoni carbonic anhydrase-related 0.0055 0.048 0.0472
Giardia lamblia 1,4-alpha-glucan branching enzyme 0.0057 0.0502 0.1082
Echinococcus granulosus tyrosine protein kinase HCK 0.0031 0.0183 0.0175
Plasmodium vivax dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative 0.0018 0.0018 0.0162
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0079 0.0777 0.1133
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0546 0.1326
Schistosoma mansoni poly(ADP-ribose) glycohydrolase 0.0156 0.1727 0.172
Onchocerca volvulus 0.0055 0.0482 0.076
Plasmodium falciparum plasmepsin III 0.0021 0.0057 0.0679
Echinococcus multilocularis aldehyde reductase 0.0048 0.0392 0.0384
Trichomonas vaginalis phosphofructokinase, putative 0.0237 0.2735 0.6638
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0021 0.0064 0.0055
Onchocerca volvulus 0.0026 0.012 0.0188
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0079 0.0777 0.1087
Treponema pallidum hypothetical protein 0.0034 0.0217 0.0489
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0033 0.0048
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0546 0.1326
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0021 0.0064 0.0055
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0041 0.0309 0.075
Echinococcus multilocularis microtubule associated protein 2 0.0825 1 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0429 0.06
Entamoeba histolytica poly(ADP-ribose) glycohydrolase, putative 0.0069 0.0659 0.1599
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0058 0.052 0.0512
Toxoplasma gondii 6-phosphofructokinase 0.0064 0.0594 0.3373
Brugia malayi Pepsin A precursor 0.0021 0.0057 0.0083
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0021 0.0064 0.0055
Loa Loa (eye worm) AGC/PKN protein kinase 0.0089 0.0899 0.1311
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.07 0.0693
Echinococcus multilocularis lamin 0.0032 0.02 0.0191
Brugia malayi 6-phosphofructokinase 0.0237 0.2735 0.3989
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0057 0.0049
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0333 0.0325
Trichomonas vaginalis alpha-amylase, putative 0.0114 0.1208 0.2931
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0064 0.0594 0.3373
Entamoeba histolytica protein kinase, putative 0.0031 0.0183 0.0444
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0055 0.0482 0.0703
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0171 0.1911 0.6944
Brugia malayi RhoGAP domain containing protein 0.0087 0.0876 0.1277
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0079 0.0777 0.0769
Onchocerca volvulus 0.0021 0.0064 0.01
Trypanosoma brucei protein tyrosine phosphatase 1 0.0021 0.0064 0.0089
Giardia lamblia Kinase, CMGC MAPK 0.0104 0.1081 0.2509
Brugia malayi hypothetical protein 0.0065 0.0606 0.0885
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0029 0.0156 0.0227
Onchocerca volvulus 0.0021 0.0064 0.01
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0049 0.041 0.0401
Echinococcus granulosus ubiquitin specific protease 41 0.0081 0.0799 0.0791
Brugia malayi jmjC domain containing protein 0.0019 0.0033 0.0048
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0546 0.0765
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0046 0.0365 0.0356
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.1291 0.1284
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0899 0.0891
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0084 0.0076
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0899 0.2181
Toxoplasma gondii transporter, major facilitator family protein 0.0055 0.0482 0.2721
Toxoplasma gondii MAPEG family protein 0.0111 0.1168 0.673
Brugia malayi jmjC domain containing protein 0.0019 0.0033 0.0048
Plasmodium falciparum carbonic anhydrase 0.0055 0.048 0.8022
Echinococcus multilocularis tissue type plasminogen activator 0.0021 0.0061 0.0053
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0061 0.056 0.1934
Brugia malayi hypothetical protein 0.053 0.6347 0.9258
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0333 0.5549
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.0722 0.0714
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0335 0.0469
Trichomonas vaginalis sucrase-isomaltase, putative 0.0043 0.0335 0.0814
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0241 0.0584
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0309 0.0604
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Echinococcus granulosus mitogen activated protein kinase 11 0.0128 0.138 0.1373
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Onchocerca volvulus 0.0021 0.0064 0.01
Onchocerca volvulus 0.0021 0.0064 0.01
Toxoplasma gondii hypothetical protein 0.0019 0.0038 0.0127
Schistosoma mansoni aldo-keto reductase 0.0067 0.0632 0.0625
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0089 0.0899 0.0891
Entamoeba histolytica phosphofructokinase, putative 0.0237 0.2735 0.6638
Onchocerca volvulus 0.0067 0.0632 0.0996
Trypanosoma brucei poly(ADP-ribose) glycohydrolase, putative 0.0156 0.1727 0.2419
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Schistosoma mansoni tyrosine kinase 0.0046 0.0365 0.0356
Echinococcus multilocularis 6 phosphofructokinase 0.0237 0.2735 0.2729
Leishmania major aldo-keto reductase-like protein 0.0067 0.0632 0.0886
Schistosoma mansoni serine/threonine kinase 0.0089 0.0899 0.0891
Mycobacterium leprae Probable lipase LipE 0.0036 0.0241 0.075
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0104 0.1081 0.6224
Leishmania major hypothetical protein, conserved 0.0036 0.0241 0.0337
Mycobacterium ulcerans lipase LipD 0.0036 0.0241 0.075
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.006 0.0546 0.1326
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0546 0.1326
Trichomonas vaginalis aldehyde oxidase, putative 0.0207 0.2362 0.5732
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0104 0.1081 0.1514
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0058 0.052 0.082
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.012 0.029
Brugia malayi hypothetical protein 0.0021 0.0064 0.0093
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0546 0.1326
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0959 0.2328
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0055 0.0482 0.0474
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Echinococcus granulosus sterol regulatory element binding protein 0.0056 0.0489 0.0481
Brugia malayi secreted modular calcium-binding protein 1 0.0038 0.0266 0.0388
Leishmania major carbonic anhydrase-like protein 0.0055 0.048 0.0672
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0099 0.1025 0.1017
Echinococcus multilocularis Diacylglycerol kinase theta 0.0079 0.0784 0.0776
Echinococcus granulosus tyrosine protein kinase Src42A 0.0046 0.0365 0.0356
Echinococcus multilocularis serine:threonine protein kinase N2 0.0089 0.0899 0.0891
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0081 0.0799 0.0791
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0309 0.0432
Echinococcus multilocularis SAM and MBT domain containing protein 0.0104 0.1089 0.1081
Loa Loa (eye worm) hypothetical protein 0.0038 0.0266 0.0388
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0018 0.0018 0.001
Loa Loa (eye worm) hypothetical protein 0.0135 0.1472 0.2147
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0026 0.012 0.0111
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.007 0.0666 0.2326
Brugia malayi Pre-SET motif family protein 0.0206 0.2343 0.3418
Entamoeba histolytica vacuolar protein sorting 26 0.0026 0.012 0.029
Brugia malayi beta-lactamase family protein 0.0036 0.0241 0.0351
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0055 0.048 0.07
Toxoplasma gondii exonuclease III APE 0.0041 0.0309 0.1707
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Echinococcus multilocularis bloom syndrome protein 0.0049 0.0409 0.0401
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.013 0.0316
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0128 0.138 0.1933
Schistosoma mansoni potassium channel beta 0.0019 0.0042 0.0033
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0021 0.0064 0.0055
Loa Loa (eye worm) hypothetical protein 0.0056 0.0489 0.0713
Schistosoma mansoni serine/threonine protein kinase 0.0341 0.4014 0.4009
Echinococcus multilocularis protein kinase c eta type 0.0079 0.0784 0.0776
Echinococcus multilocularis RNA directed DNA polymerase 0.0141 0.1549 0.1542
Schistosoma mansoni aldo-keto reductase 0.0067 0.0632 0.0625
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0021 0.0064 0.0055
Trichomonas vaginalis DNA helicase recq, putative 0.0049 0.0409 0.0993
Onchocerca volvulus 0.0036 0.0241 0.0379
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0164 0.0239
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0067 0.0632 0.0922
Loa Loa (eye worm) hypothetical protein 0.0038 0.0266 0.0388
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0033 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Schistosoma mansoni microsomal glutathione s-transferase 0.0111 0.1168 0.116
Loa Loa (eye worm) protein-tyrosine phosphatase 0.043 0.5112 0.7456
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0034 0.0224 0.0216
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0063 0.0585 0.142
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.004 0.029 0.0933
Toxoplasma gondii hypothetical protein 0.0055 0.048 0.2708
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Trypanosoma brucei protein kinase, putative 0.0104 0.1081 0.1514
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0046 0.0365 0.0356
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0034 0.0224 0.0216
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0089 0.0899 0.1311
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0026 0.012 0.029
Echinococcus multilocularis Protein lozenge 0.0066 0.0622 0.0614
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0237 0.2735 1
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0083 0.0831 0.0823
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0632 0.0625
Loa Loa (eye worm) hhat protein 0.0026 0.012 0.0174
Plasmodium vivax aspartyl protease, putative 0.0021 0.0057 0.083
Brugia malayi hypothetical protein 0.0043 0.0333 0.0486
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0831 0.0823
Loa Loa (eye worm) hypothetical protein 0.0032 0.0192 0.028
Echinococcus multilocularis expressed protein 0.0038 0.0266 0.0258
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0171 0.1913 0.2679
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Schistosoma mansoni lipoxygenase 0.0043 0.0333 0.0325
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0026 0.012 0.0111
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0064 0.0055
Loa Loa (eye worm) MBOAT family protein 0.0026 0.012 0.0174
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4121 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0104 0.1089 0.1081
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0024
Brugia malayi Hr1 repeat family protein 0.0089 0.0899 0.1311
Loa Loa (eye worm) TK protein kinase 0.0031 0.0183 0.0267
Plasmodium vivax plasmepsin IV, putative 0.0021 0.0057 0.083
Entamoeba histolytica recQ family helicase, putative 0.0017 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0154 0.171 0.2494
Loa Loa (eye worm) hypothetical protein 0.0057 0.0502 0.0733
Echinococcus granulosus Protein patched homolog 1 0.0056 0.0489 0.0481
Echinococcus granulosus aldo keto reductase 0.0067 0.0632 0.0625
Entamoeba histolytica hypothetical protein, conserved 0.0026 0.012 0.029
Brugia malayi Protein-tyrosine phosphatase containing protein 0.043 0.5112 0.7456
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.0048
Brugia malayi diacylglycerol kinase 0.0079 0.0784 0.1143
Echinococcus granulosus serine:threonine protein kinase N2 0.0089 0.0899 0.0891
Onchocerca volvulus 0.0021 0.0064 0.01
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0021 0.0064 0.0154
Entamoeba histolytica alcohol dehydrogenase, putative 0.0019 0.0042 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.3723 0.3717
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0018 0.0018 0.0025
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0018 0.0018 0.001
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0111 0.1168 0.116
Schistosoma mansoni pcd6 interacting protein-related 0.0021 0.0064 0.0055
Chlamydia trachomatis 1,4-alpha-glucan branching enzyme 0.0057 0.0502 0.8415
Trichomonas vaginalis starch branching enzyme II, putative 0.0057 0.0502 0.1219
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0026 0.012 0.0111
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) AGC/AKT protein kinase 0.0094 0.0959 0.1399
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0064 0.0594 0.1406
Echinococcus multilocularis mitogen activated protein kinase 14 0.0128 0.138 0.1373
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0566 0.0792
Plasmodium vivax JmjC domain containing protein 0.0019 0.0033 0.0416
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0104 0.1081 0.1514
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.009
Entamoeba histolytica diacylglycerol kinase, putative 0.0079 0.0784 0.1902
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0309 0.5049
Toxoplasma gondii hypothetical protein 0.0058 0.0521 0.2948
Entamoeba histolytica recQ family helicase, putative 0.0037 0.0262 0.0637
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0019 0.0042 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0546 0.1326
Echinococcus multilocularis glucan (1,4 alpha), branching enzyme 1 0.0057 0.0502 0.0494
Schistosoma mansoni agrin 0.0038 0.0266 0.0258
Entamoeba histolytica aldose reductase, putative 0.0067 0.0632 0.1535
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0026
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0171 0.1913 0.2679
Brugia malayi Kringle domain containing protein 0.0021 0.0061 0.009
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0021 0.0064 0.0055
Loa Loa (eye worm) hypothetical protein 0.0034 0.0224 0.0327
Entamoeba histolytica hypothetical protein 0.0026 0.012 0.029
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) intermediate filament protein 0.0032 0.02 0.0291
Loa Loa (eye worm) hypothetical protein 0.0055 0.0482 0.0703
Loa Loa (eye worm) hypothetical protein 0.0055 0.0482 0.0703
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0809 0.0802
Brugia malayi Protein kinase domain containing protein 0.0094 0.0959 0.1399
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Onchocerca volvulus 0.0067 0.0632 0.0996
Echinococcus multilocularis unc 13 (munc13) 0.0087 0.0876 0.0869
Onchocerca volvulus 0.0021 0.0064 0.01
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0029 0.0164 0.265
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0021 0.0064 0.0093
Brugia malayi Protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0033 0.0024
Entamoeba histolytica 1,4-alpha-glucan branching enzyme, putative 0.0057 0.0502 0.1219
Echinococcus granulosus o acyltransferase membrane bound domain 0.0026 0.012 0.0111
Echinococcus granulosus myotubularin protein 13 0.0084 0.0844 0.0837
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0081 0.0799 0.0791
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0087 0.0876 0.0868
Onchocerca volvulus 0.0234 0.2696 0.4247
Toxoplasma gondii alpha amylase, catalytic domain-containing protein 0.0057 0.0502 0.284
Loa Loa (eye worm) mbt repeat family protein 0.0104 0.1089 0.1588
Schistosoma mansoni loxhd1 0.0043 0.0333 0.0325
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0104 0.1081 0.1514
Brugia malayi jmjC domain containing protein 0.007 0.067 0.0978
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0237 0.2735 0.383
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0341 0.4014 0.5855
Loa Loa (eye worm) hypothetical protein 0.0043 0.0333 0.0486
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0959 0.2328
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0038 0.0512
Loa Loa (eye worm) hypothetical protein 0.0036 0.0241 0.0351
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) phosphofructokinase 0.0237 0.2735 0.3989
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0365 0.0356
Entamoeba histolytica protein kinase, putative 0.0094 0.0959 0.2328
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0266 0.0388
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0021 0.0064 0.0055
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0135 0.1472 0.2062
Brugia malayi Tyrosine-protein kinase abl-1 0.0017 0.0008 0.0012
Echinococcus granulosus glucan 14 alpha branching enzyme 1 0.0057 0.0502 0.0494
Trichomonas vaginalis DNA helicase recq, putative 0.0037 0.0262 0.0637
Onchocerca volvulus 0.0032 0.02 0.0314
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Echinococcus multilocularis aldo keto reductase 0.0067 0.0632 0.0625
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0085 0.0852 0.2067
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0033 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0899 0.0891
Entamoeba histolytica phosphofructokinase, putative 0.0237 0.2735 0.6638
Schistosoma mansoni cathepsin D (A01 family) 0.0021 0.0057 0.0049
Schistosoma mansoni carbonic anhydrase-related 0.0055 0.048 0.0472
Schistosoma mansoni rac gtpase activating protein 0.0079 0.0784 0.0776
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.012 0.029
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0021 0.0064 0.0055
Echinococcus granulosus dnaJ subfamily C 6 0.0134 0.1455 0.1447
Trypanosoma cruzi aldo-keto reductase 0.0067 0.0632 0.0886
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0241 0.075
Mycobacterium ulcerans hypothetical protein 0.0019 0.0042 0.0013
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.2611 0.9538
Echinococcus granulosus Protein kinase C brain isozyme 0.0317 0.3723 0.3717
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0119 0.1267 0.1259
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0021 0.0064 0.0055
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0333 0.0486
Schistosoma mansoni 6-phosphofructokinase 0.0237 0.2735 0.2729
Trypanosoma cruzi squalene monooxygenase, putative 0.0594 0.7142 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.1291 0.1284
Trypanosoma cruzi aldo/keto reductase, putative 0.0019 0.0042 0.0059
Echinococcus granulosus bloom syndrome protein 0.0049 0.0409 0.0401
Schistosoma mansoni memapsin-2 (A01 family) 0.0516 0.6176 0.6173
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0333 0.0325
Echinococcus granulosus histone lysine methyltransferase setb 0.0067 0.0626 0.0618
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0241 0.075
Loa Loa (eye worm) hypothetical protein 0.053 0.6347 0.9258
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0309 0.03
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0237 0.2735 0.6624
Schistosoma mansoni hypothetical protein 0.0134 0.1455 0.1447
Echinococcus granulosus tyrosine protein kinase Lyn 0.0049 0.0411 0.0403
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.0042 0.0102
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0064 0.0093
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0135 0.1472 0.1465
Echinococcus granulosus mitogen activated protein kinase 14 0.0128 0.138 0.1373
Loa Loa (eye worm) oxidoreductase 0.0067 0.0632 0.0922
Loa Loa (eye worm) hypothetical protein 0.0067 0.0632 0.0922
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0128 0.138 0.1933
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Echinococcus granulosus o acyltransferase membrane bound domain 0.0026 0.012 0.0111
Echinococcus granulosus NDR protein kinase 0.0089 0.0899 0.0891
Trichomonas vaginalis amylase, putative 0.0128 0.1381 0.335
Schistosoma mansoni cathepsin D (A01 family) 0.0021 0.0057 0.0049
Trypanosoma cruzi ISWI complex protein 0.0033 0.0214 0.03
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0038 0.0275 0.0267
Loa Loa (eye worm) hypothetical protein 0.0238 0.2744 0.4003
Trypanosoma cruzi poly(ADP-ribose) glycohydrolase, putative 0.0156 0.1727 0.2419
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0055 0.048 0.07
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0058 0.052 0.0512
Toxoplasma gondii dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase 0.0018 0.0018 0.0008
Schistosoma mansoni jumonji domain containing protein 0.007 0.067 0.0662
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.1089 0.1081
Schistosoma mansoni 6-phosphofructokinase 0.0237 0.2735 0.2729
Loa Loa (eye worm) hypothetical protein 0.0079 0.0784 0.1143
Plasmodium falciparum aldehyde reductase, putative 0.0019 0.0042 0.0415
Entamoeba histolytica hypothetical protein 0.0156 0.1727 0.4192
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0055 0.048 0.07
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0064 0.0093
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0027 0.013 0.0122
Plasmodium vivax SET domain protein, putative 0.0029 0.0166 0.2686
Schistosoma mansoni hypothetical protein 0.0067 0.0635 0.0627
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4121 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Brugia malayi MBOAT family protein 0.0026 0.012 0.0174
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0026 0.012 0.0111
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0063 0.0585 0.142
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0055 0.048 0.07
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0361 0.4265 0.5971
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0632 0.1535
Trichomonas vaginalis alpha-amylase, putative 0.0128 0.1381 0.335
Brugia malayi Eukaryotic aspartyl protease family protein 0.0021 0.0057 0.0083
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.02 0.0291
Trypanosoma cruzi GUP1, putative 0.0026 0.012 0.0167
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0087 0.0876 0.0868
Loa Loa (eye worm) PHD-finger family protein 0.0045 0.0358 0.0522
Schistosoma mansoni hypothetical protein 0.0099 0.1025 0.1017
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.006 0.0546 0.1326
Echinococcus multilocularis Rac GTPase activating protein 1 0.0079 0.0784 0.0776
Schistosoma mansoni microtubule-associated protein tau 0.0825 1 1
Onchocerca volvulus 0.0113 0.1194 0.1881
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0546 0.0765
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0104 0.1089 0.1715
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0455 0.1103
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0899 0.2181
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0149 0.1647 0.2403
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0429 0.06
Echinococcus granulosus N chimaerin 0.0087 0.0876 0.0868
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.0827 0.0819
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0266 0.0388
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0241 0.075
Trypanosoma cruzi ISWI complex protein 0.0033 0.0214 0.03
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0093
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0056 0.0489 0.0713
Loa Loa (eye worm) AGC/NDR protein kinase 0.0089 0.0899 0.1311
Brugia malayi CHE-14 protein 0.0056 0.0489 0.0713
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0195 0.2209 0.3222
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0171 0.1913 0.2679

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.1 uM In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase, in intestinal microsomes isolated from cholesterol-fed rabbits ChEMBL. 1578488
IC50 (binding) = 1.1 uM In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase, in intestinal microsomes isolated from cholesterol-fed rabbits ChEMBL. 1578488

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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