Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0277 | 0.2226 |
Mycobacterium ulcerans | metal cation transporter p-type ATPase a | 0.0009 | 0.0089 | 0.5 |
Mycobacterium leprae | PROBABLE CATION-TRANSPORTER ATPASE I CTPI | 0.0009 | 0.0089 | 0.5 |
Brugia malayi | Ets-domain containing protein | 0.0073 | 0.1672 | 0.2177 |
Echinococcus multilocularis | ets variant gene 4 | 0.0011 | 0.014 | 0.0084 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.027 | 0.0215 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0096 | 0.2228 | 1 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0009 | 0.0089 | 0.0399 |
Trypanosoma cruzi | cation-transporting ATPase, putative | 0.0009 | 0.0089 | 0.0378 |
Loa Loa (eye worm) | DNA-binding protein D-ETS-3 | 0.0011 | 0.014 | 0.0184 |
Toxoplasma gondii | sarco/endoplasmic reticulum Ca2+-ATPase | 0.0009 | 0.0089 | 0.0689 |
Echinococcus multilocularis | phospholipid transporting ATPase IIB | 0.0009 | 0.0089 | 0.0033 |
Schistosoma mansoni | cation-transporting atpase worm | 0.0009 | 0.0089 | 0.0084 |
Trypanosoma cruzi | phospholipid-transporting ATPase-like protein, putative | 0.0009 | 0.0089 | 0.0378 |
Echinococcus multilocularis | phosphoserine phosphatase | 0.0009 | 0.0089 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0089 | 0.0114 |
Toxoplasma gondii | phospholipid-translocating P-type ATPase, flippase subfamily protein | 0.0009 | 0.0089 | 0.0689 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.027 | 0.0215 |
Trichomonas vaginalis | ATPase, class VI, type 11C, putative | 0.0009 | 0.0089 | 0.022 |
Brugia malayi | DNA-binding protein D-ETS-3 | 0.0011 | 0.014 | 0.007 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0125 | 0.005 |
Entamoeba histolytica | cation-transporting P-typeATPase, putative | 0.0009 | 0.0089 | 0.0399 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0197 | 0.0506 |
Schistosoma mansoni | hypothetical protein | 0.0412 | 1 | 1 |
Echinococcus granulosus | protein C ets 2 | 0.0011 | 0.014 | 0.0084 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.01 | 0.0044 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0631 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0125 | 0.0163 |
Echinococcus granulosus | dual specificity | 0.009 | 0.2096 | 0.2051 |
Entamoeba histolytica | plasma membrane calcium ion-transporting ATPase, putative | 0.0009 | 0.0089 | 0.0399 |
Schistosoma mansoni | eyes absent homolog | 0.0089 | 0.206 | 0.2056 |
Schistosoma mansoni | elf1 | 0.0011 | 0.014 | 0.0135 |
Schistosoma mansoni | kinase | 0.0049 | 0.1079 | 0.1075 |
Trypanosoma cruzi | copper-transporting ATPase-like protein, putative | 0.0009 | 0.0089 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0723 | 0.0977 |
Brugia malayi | Protein kinase domain containing protein | 0.009 | 0.2096 | 0.2761 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.027 | 0.0265 |
Trichomonas vaginalis | cation-transporting ATPase fungi, putative | 0.0009 | 0.0089 | 0.022 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0011 | 0.014 | 0.0084 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0096 | 0.2228 | 0.2943 |
Schistosoma mansoni | phosphoserine phosphatase | 0.0009 | 0.0089 | 0.0084 |
Trypanosoma cruzi | Calcium ATPase SERCA-like | 0.0009 | 0.0089 | 0.0378 |
Plasmodium vivax | copper-transporting ATPase, putative | 0.0009 | 0.0089 | 0.316 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0197 | 0.0715 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.1113 | 0.1508 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.027 | 0.0265 |
Echinococcus multilocularis | Tetracycline resistance leader peptide, TetL | 0.0009 | 0.0089 | 0.0033 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0041 | 0.00000000046215 |
Echinococcus multilocularis | phosphoserine phosphatase | 0.0009 | 0.0089 | 0.0033 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2228 | 1 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0125 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.2077 | 0.2818 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0089 | 0.0114 |
Toxoplasma gondii | haloacid dehalogenase family hydrolase domain-containing protein | 0.0009 | 0.0089 | 0.0689 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0125 | 0.005 |
Plasmodium vivax | P-type ATPase4, putative | 0.0009 | 0.0089 | 0.316 |
Echinococcus multilocularis | dual specificity | 0.009 | 0.2096 | 0.2051 |
Toxoplasma gondii | P-type ATPase4, putative | 0.0009 | 0.0089 | 0.0689 |
Echinococcus multilocularis | cation transporting ATPase 13A3 | 0.0009 | 0.0089 | 0.0033 |
Toxoplasma gondii | haloacid dehalogenase family hydrolase domain-containing protein | 0.0009 | 0.0089 | 0.0689 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0096 | 0.2228 | 0.3024 |
Echinococcus multilocularis | phosphoserine phosphatase | 0.0009 | 0.0089 | 0.0033 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.1387 | 0.1383 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.014 | 0.0135 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.027 | 0.0215 |
Trypanosoma cruzi | P-type H+-ATPase, putative | 0.0009 | 0.0089 | 0.0378 |
Echinococcus multilocularis | ewsr:fli fusion protein type | 0.0011 | 0.014 | 0.0084 |
Echinococcus granulosus | ETS transcription factor Elf 5 | 0.0011 | 0.014 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.206 | 0.2795 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1412 | 0.1913 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0096 | 0.2228 | 0.2225 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0016 | 0.0281 | 1 |
Mycobacterium ulcerans | metal cation-transporting p-type ATPase F, CtpF | 0.0009 | 0.0089 | 0.5 |
Echinococcus granulosus | sarco:endoplasmic reticulum calcium ATPase | 0.0009 | 0.0089 | 0.0033 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0631 | 0.0578 |
Entamoeba histolytica | phospholipid-transporting P-type ATPase, putative | 0.0009 | 0.0089 | 0.0399 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.1113 | 0.1409 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0089 | 0.0114 |
Entamoeba histolytica | phospholipid-transporting P-type ATPase, putative | 0.0009 | 0.0089 | 0.0399 |
Schistosoma mansoni | cation-transporting ATPase | 0.0009 | 0.0089 | 0.0084 |
Mycobacterium tuberculosis | Probable metal cation transporter ATPase P-type CtpE | 0.0009 | 0.0089 | 0.5 |
Schistosoma mansoni | ets-related | 0.0222 | 0.532 | 0.5317 |
Brugia malayi | hypothetical protein | 0.0304 | 0.7357 | 1 |
Entamoeba histolytica | plasma membrane calcium-transporting ATPase 1, putative | 0.0009 | 0.0089 | 0.0399 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0041 | 0.00000000046215 |
Toxoplasma gondii | P-type ATPase PMA1 | 0.0009 | 0.0089 | 0.0689 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.027 | 0.0361 |
Mycobacterium ulcerans | metal cation transporter ATPase p-type CtpE | 0.0009 | 0.0089 | 0.5 |
Schistosoma mansoni | ets | 0.0011 | 0.014 | 0.0135 |
Loa Loa (eye worm) | ets-domain-containing protein | 0.0011 | 0.014 | 0.0184 |
Echinococcus multilocularis | copper transporting ATPase 1 | 0.0009 | 0.0089 | 0.0033 |
Echinococcus multilocularis | cation transporting ATPase 13A1 | 0.0009 | 0.0089 | 0.0033 |
Trypanosoma cruzi | copper-transporting ATPase-like protein, putative | 0.0009 | 0.0089 | 0.0378 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0097 | 0.0011 |
Trypanosoma cruzi | proton motive ATPase 1, putative | 0.0009 | 0.0089 | 0.0378 |
Entamoeba histolytica | calcium-transporting P-type ATPase, putative | 0.0009 | 0.0089 | 0.0399 |
Schistosoma mansoni | copper ABC transporter ATPase | 0.0009 | 0.0089 | 0.0084 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0009 | 0.0089 | 0.0378 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0011 | 0.014 | 0.0184 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0041 | 0.00000000046215 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0011 | 0.014 | 0.0084 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2228 | 1 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0011 | 0.014 | 0.0084 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.1113 | 0.1409 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0125 | 0.0069 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0125 | 0.0069 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0125 | 0.0069 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.1226 | 1 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.009 | 0.2096 | 0.9379 |
Toxoplasma gondii | phospholipid-translocating P-type ATPase, flippase subfamily protein | 0.0009 | 0.0089 | 0.0689 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0125 | 0.0984 |
Trichomonas vaginalis | ATPase, class I, type 8B, putative | 0.0009 | 0.0089 | 0.022 |
Loa Loa (eye worm) | D-ets-2 protein | 0.0011 | 0.014 | 0.0184 |
Brugia malayi | Ets-domain containing protein | 0.0011 | 0.014 | 0.007 |
Brugia malayi | Ets-domain containing protein | 0.0073 | 0.1672 | 0.2177 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Entamoeba histolytica | recQ family DNA helicase | 0.0005 | 0.0005 | 0.0021 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.009 | 0.2096 | 0.9403 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0041 | 0.00000000046215 |
Loa Loa (eye worm) | calcium ATPase | 0.0009 | 0.0089 | 0.0114 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0073 | 0.1672 | 0.1624 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0041 | 0.00000000046215 |
Schistosoma mansoni | cation-transporting atpase worm | 0.0009 | 0.0089 | 0.0084 |
Echinococcus granulosus | cation transporting ATPase 13A3 | 0.0009 | 0.0089 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.2077 | 0.2818 |
Echinococcus multilocularis | phosphoserine phosphatase | 0.0009 | 0.0089 | 0.0033 |
Echinococcus granulosus | calcium transporting ATPase type 2C member | 0.0009 | 0.0089 | 0.0033 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.027 | 0.0215 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.001 | 0.0125 | 0.1153 |
Schistosoma mansoni | polyomavirus enhancer activator 3 pea3 | 0.0011 | 0.014 | 0.0135 |
Echinococcus granulosus | cation transporting atpase worm | 0.0009 | 0.0089 | 0.0033 |
Trypanosoma cruzi | copper-transporting ATPase, putative | 0.0009 | 0.0089 | 0.0378 |
Schistosoma mansoni | ATPase | 0.0009 | 0.0089 | 0.0084 |
Loa Loa (eye worm) | sodium/potassium-transporting ATPase subunit alpha | 0.0009 | 0.0089 | 0.0114 |
Echinococcus granulosus | copper transporting ATPase 1 | 0.0009 | 0.0089 | 0.0033 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0096 | 0.2228 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2228 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.059 | 0.069 |
Mycobacterium ulcerans | cation transporter p-type ATPase a CtpA | 0.0009 | 0.0089 | 0.5 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0073 | 0.1672 | 0.2267 |
Schistosoma mansoni | Na+/K+ transporting ATPase subunit alpha | 0.0009 | 0.0089 | 0.0084 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0631 | 0.0626 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.027 | 0.0361 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0125 | 0.0984 |
Mycobacterium leprae | Probable metal cation-transporting P-type ATPase C CtpC | 0.0009 | 0.0089 | 0.5 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Brugia malayi | hypothetical protein | 0.0089 | 0.206 | 0.2712 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0125 | 0.012 |
Mycobacterium ulcerans | cation-transporter ATPase I CtpI | 0.0009 | 0.0089 | 0.5 |
Entamoeba histolytica | recQ family helicase, putative | 0.0013 | 0.0197 | 0.0885 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0125 | 0.0163 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Loa Loa (eye worm) | fli-1 protein | 0.0222 | 0.532 | 0.7229 |
Echinococcus granulosus | ETS transcription factor Elf 1 | 0.0011 | 0.014 | 0.0084 |
Schistosoma mansoni | gabp alpha | 0.0073 | 0.1672 | 0.1668 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0056 | 0.0052 |
Schistosoma mansoni | type V p-type atpase isoform | 0.0009 | 0.0089 | 0.0084 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0041 | 0.00000000046215 |
Mycobacterium tuberculosis | Possible metal cation transporting P-type ATPase CtpH | 0.0009 | 0.0089 | 0.5 |
Echinococcus multilocularis | calcium transporting ATPase type 2C member | 0.0009 | 0.0089 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0089 | 0.0114 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.009 | 0.2096 | 0.2844 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0197 | 0.0506 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.027 | 0.0249 |
Echinococcus granulosus | ETS domain containing protein Elk 1 | 0.0011 | 0.014 | 0.0084 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.027 | 0.0215 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.027 | 0.0215 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0041 | 0.00000000046215 |
Mycobacterium tuberculosis | Probable cation transporter P-type ATPase D CtpD | 0.0009 | 0.0089 | 0.5 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0474 | 0.1979 |
Toxoplasma gondii | cation-transporting atpase family protein | 0.0009 | 0.0089 | 0.0689 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0041 | 0.00000000046215 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2228 | 1 |
Loa Loa (eye worm) | E1-E2 ATPase | 0.0009 | 0.0089 | 0.0114 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2228 | 1 |
Trichomonas vaginalis | phospholipid-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Mycobacterium ulcerans | cation-transporter p-type ATPase B CtpB | 0.0009 | 0.0089 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.027 | 0.0249 |
Schistosoma mansoni | serine/threonine protein kinase | 0.009 | 0.2096 | 0.2092 |
Echinococcus granulosus | cation transporting ATPase 13A1 | 0.0009 | 0.0089 | 0.0033 |
Mycobacterium tuberculosis | Cation transporter P-type ATPase a CtpA | 0.0009 | 0.0089 | 0.5 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0474 | 0.042 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.059 | 0.0796 |
Echinococcus multilocularis | phospholipid transporting ATPase VA | 0.0009 | 0.0089 | 0.0033 |
Treponema pallidum | cation-transporting ATPase, P-type | 0.0009 | 0.0089 | 1 |
Echinococcus multilocularis | protein C ets 2 | 0.0011 | 0.014 | 0.0084 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0009 | 0.0089 | 0.0399 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.009 | 0.2096 | 0.9403 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0412 | 1 | 1 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0474 | 0.0638 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0048 | 0.1048 | 0.4605 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0197 | 0.0865 |
Brugia malayi | transcription factor E74 isoform | 0.0011 | 0.014 | 0.007 |
Echinococcus multilocularis | phosphoserine phosphatase | 0.0009 | 0.0089 | 0.0033 |
Echinococcus multilocularis | cation transporting atpase worm | 0.0009 | 0.0089 | 0.0033 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.001 | 0.0125 | 0.0169 |
Trypanosoma brucei | polo-like protein kinase | 0.0096 | 0.2228 | 1 |
Schistosoma mansoni | atpase class VI type 11c | 0.0009 | 0.0089 | 0.0084 |
Schistosoma mansoni | ets-related | 0.0011 | 0.014 | 0.0135 |
Trypanosoma cruzi | copper-transporting ATPase-like protein, putative | 0.0009 | 0.0089 | 0.0378 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.009 | 0.2096 | 0.9379 |
Echinococcus multilocularis | ETS domain containing protein Elk 1 | 0.0011 | 0.014 | 0.0084 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.01 | 0.0129 |
Onchocerca volvulus | 0.0029 | 0.059 | 0.069 | |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.027 | 0.0265 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0125 | 0.0069 |
Echinococcus multilocularis | sarco:endoplasmic reticulum calcium ATPase | 0.0009 | 0.0089 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.4072 | 0.407 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase 2 | 0.0009 | 0.0089 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.027 | 0.0265 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0474 | 0.1979 |
Echinococcus multilocularis | geminin | 0.0171 | 0.4072 | 0.4039 |
Brugia malayi | Fli-1 protein | 0.0222 | 0.532 | 0.7196 |
Echinococcus granulosus | phospholipid transporting ATPase VA | 0.0009 | 0.0089 | 0.0033 |
Mycobacterium ulcerans | metal cation transporter p-type ATPase, CtpV | 0.0009 | 0.0089 | 0.5 |
Mycobacterium tuberculosis | Probable metal cation transporter P-type ATPase CtpV | 0.0009 | 0.0089 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0631 | 0.0626 |
Plasmodium vivax | calcium-transporting ATPase, putative | 0.0009 | 0.0089 | 0.316 |
Echinococcus multilocularis | ETS transcription factor Elf 1 | 0.0011 | 0.014 | 0.0084 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2228 | 1 |
Mycobacterium ulcerans | metal cation-transporting p-type ATPase CtpC | 0.0009 | 0.0089 | 0.5 |
Echinococcus granulosus | ewsr:fli fusion protein type | 0.0011 | 0.014 | 0.0084 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0474 | 0.042 |
Echinococcus multilocularis | phosphoserine phosphatase | 0.0009 | 0.0089 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0089 | 0.0114 |
Loa Loa (eye worm) | Na,K-ATPase alpha subunit | 0.0009 | 0.0089 | 0.0114 |
Echinococcus multilocularis | ETS transcription factor Elf 5 | 0.0011 | 0.014 | 0.0084 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0723 | 0.0719 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0009 | 0.0089 | 0.022 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.014 | 0.0135 |
Mycobacterium ulcerans | cation transporter p-type ATPase D CtpD | 0.0009 | 0.0089 | 0.5 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0096 | 0.2228 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0096 | 0.2228 | 1 |
Chlamydia trachomatis | metal transport ATPase | 0.0009 | 0.0089 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.009 | 0.2096 | 0.9404 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2228 | 1 |
Toxoplasma gondii | calcium-translocating P-type ATPase, PMCA-type protein | 0.0009 | 0.0089 | 0.0689 |
Echinococcus granulosus | phospholipid transporting ATPase IIB | 0.0009 | 0.0089 | 0.0033 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0096 | 0.2228 | 0.2184 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.0349 | 0.0344 |
Onchocerca volvulus | 0.0304 | 0.7357 | 1 | |
Echinococcus granulosus | geminin | 0.0171 | 0.4072 | 0.4039 |
Toxoplasma gondii | heavy metal translocating P-type ATPase subfamily protein | 0.0009 | 0.0089 | 0.0689 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0402 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0096 | 0.2228 | 0.2943 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0048 | 0.1048 | 0.4605 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.014 | 0.0184 |
Giardia lamblia | Kinase, PLK | 0.0096 | 0.2228 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.4072 | 0.407 |
Entamoeba histolytica | phospholipid-transporting P-type ATPase, putative | 0.0009 | 0.0089 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0304 | 0.7357 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.009 | 0.2096 | 0.9404 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0073 | 0.1672 | 0.1624 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0011 | 0.014 | 0.0084 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.01 | 0.0044 |
Trypanosoma cruzi | P-type H+-ATPase, putative | 0.0009 | 0.0089 | 0.0378 |
Entamoeba histolytica | hypothetical protein | 0.009 | 0.2096 | 0.9404 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0009 | 0.0089 | 0.0378 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.059 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.287 | 0.3896 |
Schistosoma mansoni | cation-transporting atpase 13a1 (G-box binding protein) | 0.0009 | 0.0089 | 0.0084 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0009 | 0.0089 | 0.0399 |
Mycobacterium leprae | PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB | 0.0009 | 0.0089 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1113 | 0.1508 |
Schistosoma mansoni | ATPase | 0.0009 | 0.0089 | 0.0084 |
Entamoeba histolytica | protein kinase domain containing protein | 0.009 | 0.2096 | 0.9404 |
Treponema pallidum | hypothetical protein | 0.0009 | 0.0089 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.014 | 0.0184 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0096 | 0.2228 | 0.2184 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0723 | 0.0872 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0474 | 0.0529 |
Plasmodium vivax | cation transporting ATPase, putative | 0.0009 | 0.0089 | 0.316 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.206 | 0.2795 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -0.68 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 0 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 3.69 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 4.73 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 25 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 74 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 93 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition frequency index (IFI) (functional) | = 12.86 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
Percent growth inhibition (functional) | = -5 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 25 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 74 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 93 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
XC50 (functional) | = 5.95 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
XC50 (functional) | = 1.12876 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.