Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.15 | 0.2907 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.15 | 0.2907 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0086 | 0.0167 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0086 | 0.0167 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0412 | 0.5976 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.0086 | 0.0575 |
Onchocerca volvulus | 0.0034 | 0.0429 | 0.2859 | |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0086 | 0.0144 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0086 | 0.0167 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0348 | 0.0674 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0086 | 0.0167 |
Echinococcus multilocularis | neuroligin | 0.0034 | 0.0429 | 0.0718 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0107 | 0.15 | 0.2907 |
Onchocerca volvulus | 0.0107 | 0.15 | 1 | |
Onchocerca volvulus | 0.0107 | 0.15 | 1 | |
Mycobacterium tuberculosis | Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) | 0.0169 | 0.2402 | 0.2062 |
Onchocerca volvulus | 0.0034 | 0.0429 | 0.2859 | |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0824 | 0.138 |
Loa Loa (eye worm) | TAR-binding protein | 0.0125 | 0.1763 | 0.3415 |
Onchocerca volvulus | 0.0034 | 0.0429 | 0.2859 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.1763 | 0.295 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0086 | 0.0167 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1256 | 0.2101 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0086 | 0.0144 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0107 | 0.15 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0372 | 0.0623 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0429 | 0.0718 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0006 | 0.0009 | 0.0018 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0107 | 0.15 | 0.5428 |
Mycobacterium leprae | Probable lipase LipE | 0.0107 | 0.15 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.1256 | 0.2433 |
Schistosoma mansoni | hypothetical protein | 0.0244 | 0.3504 | 0.5863 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0086 | 0.0144 |
Echinococcus granulosus | geminin | 0.037 | 0.5367 | 0.898 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.15 | 0.2907 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0086 | 0.0144 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0086 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0429 | 0.0831 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0113 | 0.158 | 0.3062 |
Onchocerca volvulus | 0.0011 | 0.0086 | 0.0575 | |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0086 | 0.0167 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0429 | 0.0831 |
Echinococcus multilocularis | acetylcholinesterase | 0.0204 | 0.2918 | 0.4882 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0372 | 0.0623 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0086 | 0.0167 |
Mycobacterium tuberculosis | Conserved protein | 0.0107 | 0.15 | 0.1119 |
Mycobacterium ulcerans | epoxide hydrolase EphA | 0.0169 | 0.2402 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0356 | 0.5161 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0054 | 0.0091 |
Schistosoma mansoni | hypothetical protein | 0.0412 | 0.5976 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0816 | 0.1365 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0086 | 0.0167 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0006 | 0.0009 | 0.0015 |
Echinococcus granulosus | acetylcholinesterase | 0.0204 | 0.2918 | 0.4882 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0029 | 0.0048 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.1256 | 0.2433 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0086 | 0.0144 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0034 | 0.0429 | 0.0718 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0429 | 0.0831 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0029 | 0.0048 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0086 | 0.0144 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0086 | 0.0144 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0816 | 0.1365 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1256 | 0.2101 |
Loa Loa (eye worm) | RNA binding protein | 0.0125 | 0.1763 | 0.3415 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0034 | 0.0429 | 0.0718 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.2918 | 0.5653 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0086 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0429 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.15 | 0.2907 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.15 | 0.2907 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.1256 | 0.2101 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0006 | 0.0009 | 0.0015 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.0086 | 0.0575 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0816 | 0.196 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.1763 | 0.295 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0086 | 0.0144 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0086 | 0.0167 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0086 | 0.0144 |
Echinococcus multilocularis | acetylcholinesterase | 0.0204 | 0.2918 | 0.4882 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0086 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0009 | 0.0018 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0107 | 0.15 | 0.2907 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0086 | 0.0167 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0086 | 0.0167 |
Onchocerca volvulus | 0.0107 | 0.15 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.5161 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0107 | 0.15 | 0.1119 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0029 | 0.0048 |
Schistosoma mansoni | gliotactin | 0.0034 | 0.0429 | 0.0718 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0086 | 0.0144 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0113 | 0.158 | 0.2645 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0009 | 0.0018 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.158 | 0.2645 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0816 | 0.196 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0086 | 0.0167 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0348 | 0.0674 |
Echinococcus granulosus | carboxylesterase 5A | 0.0204 | 0.2918 | 0.4882 |
Onchocerca volvulus | 0.0029 | 0.0348 | 0.2319 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0086 | 0.0167 |
Mycobacterium leprae | conserved hypothetical protein | 0.0107 | 0.15 | 0.5 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0429 | 0.0831 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0054 | 0.0105 |
Brugia malayi | Carboxylesterase family protein | 0.0204 | 0.2918 | 0.5653 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.0086 | 0.0575 |
Mycobacterium ulcerans | beta-lactamase | 0.0107 | 0.15 | 0.5428 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0429 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0086 | 0.0167 |
Echinococcus granulosus | GPCR family 2 | 0.0113 | 0.158 | 0.2645 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0429 | 0.0718 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0372 | 0.0623 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.158 | 0.2645 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.2918 | 0.5653 |
Schistosoma mansoni | hypothetical protein | 0.037 | 0.5367 | 0.898 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0034 | 0.0429 | 0.0718 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0107 | 0.15 | 0.1119 |
Plasmodium vivax | hypothetical protein, conserved | 0.0107 | 0.15 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0086 | 0.0167 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0009 | 0.0018 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0034 | 0.0429 | 0.0718 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0029 | 0.0048 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.1763 | 0.295 |
Mycobacterium ulcerans | lipase LipD | 0.0107 | 0.15 | 0.5428 |
Echinococcus granulosus | tar DNA binding protein | 0.0125 | 0.1763 | 0.295 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0086 | 0.0144 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0372 | 0.0623 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0009 | 0.0018 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0107 | 0.15 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0086 | 0.0167 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0086 | 0.0167 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0429 | 0.0831 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0107 | 0.15 | 0.251 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0006 | 0.0009 | 0.0015 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0034 | 0.0429 | 0.2767 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.1763 | 0.295 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0113 | 0.158 | 0.3062 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0086 | 0.0144 |
Echinococcus multilocularis | geminin | 0.037 | 0.5367 | 0.898 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0086 | 0.0144 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0107 | 0.15 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0009 | 0.0018 |
Mycobacterium tuberculosis | Conserved protein | 0.0107 | 0.15 | 0.1119 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0107 | 0.15 | 0.251 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0009 | 0.0018 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0113 | 0.158 | 0.2645 |
Leishmania major | hypothetical protein, conserved | 0.0107 | 0.15 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0107 | 0.15 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.158 | 0.2645 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0034 | 0.0429 | 0.0718 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0054 | 0.0091 |
Mycobacterium tuberculosis | Conserved protein | 0.0107 | 0.15 | 0.1119 |
Brugia malayi | RNA binding protein | 0.0125 | 0.1763 | 0.3415 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0204 | 0.2918 | 0.4882 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0086 | 0.0167 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0107 | 0.15 | 1 |
Onchocerca volvulus | 0.0034 | 0.0429 | 0.2859 | |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0429 | 0.0831 |
Echinococcus granulosus | acetylcholinesterase | 0.0204 | 0.2918 | 0.4882 |
Schistosoma mansoni | hypothetical protein | 0.037 | 0.5367 | 0.898 |
Echinococcus multilocularis | tar DNA binding protein | 0.0125 | 0.1763 | 0.295 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0086 | 0.0144 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0244 | 0.3504 | 0.6789 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0429 | 0.0718 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0086 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0086 | 0.0167 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0086 | 0.0144 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0086 | 0.0167 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0125 | 0.1763 | 0.3415 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0006 | 0.0009 | 0.0015 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0348 | 0.0582 |
Brugia malayi | nuclear receptor RXR | 0.0006 | 0.0009 | 0.0018 |
Schistosoma mansoni | acetylcholinesterase | 0.0034 | 0.0429 | 0.0718 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0009 | 0.0018 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0107 | 0.15 | 0.1119 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0086 | 0.0144 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0113 | 0.158 | 0.3062 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0086 | 0.0167 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0204 | 0.2918 | 0.5653 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0086 | 0.0144 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.1256 | 0.2101 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.0816 | 0.0404 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0086 | 0.0144 |
Brugia malayi | TAR-binding protein | 0.0125 | 0.1763 | 0.3415 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.158 | 0.2645 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0086 | 0.0167 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0816 | 0.1135 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.1256 | 0.2101 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0086 | 0.0167 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0034 | 0.0429 | 0.0718 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0086 | 0.0167 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0125 | 0.1763 | 0.3415 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0429 | 0.0831 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0053 | 0.0102 |
Loa Loa (eye worm) | carboxylesterase | 0.0034 | 0.0429 | 0.0831 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0086 | 0.0144 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0107 | 0.15 | 0.1119 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0086 | 0.0167 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0086 | 0.0167 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0816 | 0.1365 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0429 | 0.0831 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0107 | 0.15 | 0.251 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0107 | 0.15 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0107 | 0.15 | 0.2907 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0086 | 0.0144 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.1763 | 0.295 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0107 | 0.15 | 0.1119 |
Brugia malayi | Carboxylesterase family protein | 0.0204 | 0.2918 | 0.5653 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.0816 | 0.1365 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1256 | 0.2101 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.3504 | 0.6789 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0086 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0429 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0009 | 0.0018 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0034 | 0.0429 | 0.0718 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0086 | 0.0144 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0086 | 0.0144 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0086 | 0.0167 |
Loa Loa (eye worm) | carboxylesterase | 0.0204 | 0.2918 | 0.5653 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0086 | 0.0167 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0204 | 0.2918 | 0.4882 |
Brugia malayi | beta-lactamase family protein | 0.0107 | 0.15 | 0.2907 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.158 | 0.3062 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0107 | 0.15 | 0.1119 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0086 | 0.0167 |
Loa Loa (eye worm) | carboxylesterase | 0.0034 | 0.0429 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0086 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0086 | 0.0167 |
Echinococcus granulosus | dnaJ subfamily B | 0.0412 | 0.5976 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0107 | 0.15 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0086 | 0.0144 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0107 | 0.15 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0113 | 0.158 | 0.2645 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.15 | 0.2907 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0086 | 0.0167 |
Onchocerca volvulus | 0.0034 | 0.0429 | 0.2859 | |
Loa Loa (eye worm) | beta-lactamase | 0.0107 | 0.15 | 0.2907 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.1256 | 0.2101 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0009 | 0.0018 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0107 | 0.15 | 0.251 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0816 | 0.196 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0086 | 0.0144 |
Toxoplasma gondii | ABC1 family protein | 0.0107 | 0.15 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0429 | 0.0831 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0086 | 0.0144 |
Mycobacterium ulcerans | hypothetical protein | 0.0107 | 0.15 | 0.5428 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0086 | 0.0144 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0034 | 0.0429 | 0.2767 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0086 | 0.0144 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0107 | 0.15 | 0.5428 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0356 | 0.5161 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0034 | 0.0429 | 0.0718 |
Echinococcus granulosus | neuroligin | 0.0034 | 0.0429 | 0.0718 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0086 | 0.0167 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0356 | 0.5161 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0113 | 0.158 | 0.2645 |
Brugia malayi | beta-lactamase | 0.0107 | 0.15 | 0.2907 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0107 | 0.15 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0086 | 0.0167 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0107 | 0.15 | 0.1119 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0113 | 0.158 | 0.2645 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0029 | 0.0048 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0086 | 0.0144 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -1.04 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = -1.01 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 1 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 1.71 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 28 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 53 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 96 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition frequency index (IFI) (functional) | = 11.27 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 1 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 28 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 53 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 96 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
XC50 (functional) | = 6.07 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
XC50 (functional) | = 0.84505 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.