Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0169 | 0.0123 |
Plasmodium falciparum | polyprenol reductase, putative | 0.0044 | 0.0359 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0486 | 0.5911 | 0.5908 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0007 | 0.0017 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0486 | 0.5911 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0385 | 0.0378 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0092 | 0.0964 | 0.0957 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0125 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0652 | 0.0645 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0174 | 0.0167 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0261 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0283 | 0.0276 |
Brugia malayi | hypothetical protein | 0.0107 | 0.1152 | 0.1939 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0021 | 0.0024 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0233 | 0.0383 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0207 | 0.2408 | 0.4067 |
Schistosoma mansoni | acetylcholinesterase | 0.0046 | 0.0385 | 0.0902 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0359 | 0.0352 |
Echinococcus granulosus | chromobox protein 1 | 0.0152 | 0.1723 | 0.2906 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0261 | 0.0378 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.0044 | 0.0359 | 0.0354 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0025 | 0.0125 | 0.02 |
Onchocerca volvulus | 0.0036 | 0.0261 | 0.0448 | |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0051 | 0.0448 | 0.0443 |
Brugia malayi | MAP kinase sur-1 | 0.0051 | 0.0453 | 0.0754 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.0203 | 0.0332 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0028 | 0.0169 | 0.0162 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0025 | 0.0125 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.013 | 0.0123 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0385 | 0.0639 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0261 | 0.0704 |
Schistosoma mansoni | jumonji domain containing protein | 0.0081 | 0.0829 | 0.1943 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0085 | 0.0883 | 0.2121 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0356 | 0.0349 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0964 | 0.2259 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0207 | 0.2408 | 0.6388 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0051 | 0.0453 | 0.0916 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0064 | 0.0619 | 0.0612 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0282 | 0.0465 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0261 | 0.0429 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.0309 | 0.3699 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0207 | 0.0229 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0046 | 0.0385 | 0.0639 |
Echinococcus granulosus | Chromobox protein 3 | 0.0025 | 0.0125 | 0.02 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0021 | 0.005 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0025 | 0.0125 | 0.0119 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0046 | 0.0385 | 0.0366 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0046 | 0.0385 | 0.038 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0036 | 0.0259 | 0.0253 |
Onchocerca volvulus | 0.0046 | 0.0385 | 0.086 | |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0046 | 0.0385 | 0.038 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0453 | 0.0916 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0203 | 0.0196 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.0203 | 0.0476 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0051 | 0.0448 | 0.0747 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0207 | 0.2408 | 0.6388 |
Echinococcus multilocularis | peregrin | 0.0033 | 0.0232 | 0.0226 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0041 | 0.0329 | 0.0772 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0207 | 0.2408 | 0.4067 |
Onchocerca volvulus | 0.0025 | 0.0125 | 0.000000058117 | |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0261 | 0.0005 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0233 | 0.274 | 0.2734 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0261 | 0.0005 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0125 | 0.02 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0261 | 0.0611 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0207 | 0.2408 | 0.2415 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0021 | 0.005 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.027 | 0.3199 | 0.7499 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0482 | 0.0475 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.0752 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0883 | 0.0877 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0125 | 0.0118 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.0044 | 0.0359 | 0.0596 |
Onchocerca volvulus | 0.0059 | 0.0552 | 0.1414 | |
Plasmodium vivax | polyprenol reductase, putative | 0.0044 | 0.0359 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0065 | 0.0058 |
Echinococcus granulosus | acetylcholinesterase | 0.027 | 0.3199 | 0.5406 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0028 | 0.0169 | 0.0123 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0051 | 0.0453 | 0.0446 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.0453 | 0.1223 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0044 | 0.0359 | 0.0655 |
Schistosoma mansoni | single-minded | 0.0048 | 0.0416 | 0.0974 |
Echinococcus granulosus | chromobox protein 1 | 0.0152 | 0.1723 | 0.2906 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.1693 | 0.1687 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0309 | 0.3699 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0207 | 0.2408 | 0.5646 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0428 | 0.0421 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0207 | 0.2408 | 0.651 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.013 | 0.02 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0046 | 0.0385 | 0.0726 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0051 | 0.0453 | 0.1223 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0044 | 0.0359 | 0.0842 |
Brugia malayi | jmjC domain containing protein | 0.0041 | 0.0329 | 0.0545 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0044 | 0.0359 | 0.0655 |
Trypanosoma brucei | protein kinase, putative | 0.0051 | 0.0453 | 0.1223 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0123 | 0.1364 | 0.1364 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0059 | 0.0552 | 0.1294 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0615 | 0.1442 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0174 | 0.0408 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0051 | 0.0453 | 0.1223 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0092 | 0.0964 | 0.162 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.0093 | 0.0145 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0046 | 0.0385 | 0.0902 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0385 | 0.0639 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0051 | 0.0453 | 0.1132 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0046 | 0.0385 | 0.0726 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0046 | 0.0385 | 0.0639 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0261 | 0.0005 |
Trypanosoma brucei | polo-like protein kinase | 0.0207 | 0.2408 | 0.651 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0025 | 0.0125 | 0.0294 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0261 | 0.578 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0102 | 0.1091 | 0.1836 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0261 | 0.0429 |
Onchocerca volvulus | 0.0044 | 0.0359 | 0.0775 | |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0385 | 0.0639 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.0385 | 0.0902 |
Brugia malayi | bHLH-PAS transcription factor | 0.0036 | 0.0259 | 0.0426 |
Echinococcus granulosus | peregrin | 0.0033 | 0.0232 | 0.0381 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0123 | 0.1364 | 0.3686 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.0964 | 0.0962 |
Echinococcus multilocularis | acetylcholinesterase | 0.027 | 0.3199 | 0.321 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0261 | 0.0378 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0565 | 0.0944 |
Onchocerca volvulus | 0.0265 | 0.3143 | 1 | |
Entamoeba histolytica | hypothetical protein | 0.0044 | 0.0359 | 0.0655 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0207 | 0.2408 | 0.6388 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.0615 | 0.0608 |
Loa Loa (eye worm) | hypothetical protein | 0.0811 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0615 | 0.1442 |
Schistosoma mansoni | chromobox protein | 0.0152 | 0.1723 | 0.4039 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0046 | 0.0385 | 0.0514 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0007 | 0.0017 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0428 | 0.0712 |
Schistosoma mansoni | chromobox protein | 0.0152 | 0.1723 | 0.4039 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.013 | 0.0351 |
Brugia malayi | hypothetical protein | 0.0161 | 0.1836 | 0.3097 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0019 | 0.0045 | 0.0106 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0046 | 0.0385 | 0.0639 |
Schistosoma mansoni | kinase | 0.0105 | 0.1135 | 0.266 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0964 | 0.2259 |
Entamoeba histolytica | trans-2,3-enoyl-CoA reductase, putative | 0.0044 | 0.0359 | 0.0655 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0218 | 0.0511 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0022 | 0.0089 | 0.0139 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.0453 | 0.1223 |
Loa Loa (eye worm) | helicase | 0.0025 | 0.0125 | 0.0118 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0565 | 0.0561 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.0385 | 0.0902 |
Schistosoma mansoni | survival motor neuron protein | 0.0099 | 0.1056 | 0.2477 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0109 | 0.0173 |
Trichomonas vaginalis | chromobox protein, putative | 0.0092 | 0.0965 | 0.2349 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0207 | 0.2408 | 0.2403 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.11 | 0.2728 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0125 | 0.0118 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.0359 | 0.0971 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0428 | 0.0712 |
Echinococcus multilocularis | neuroligin | 0.0046 | 0.0385 | 0.038 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0261 | 0.0704 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0028 | 0.0163 | 0.0106 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0046 | 0.0385 | 0.0514 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0233 | 0.0547 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.0203 | 0.0196 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0228 | 0.2674 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.1056 | 0.2477 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0261 | 0.0378 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0065 | 0.0153 |
Brugia malayi | Bromodomain containing protein | 0.0033 | 0.0232 | 0.0381 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.0615 | 0.0611 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.3199 | 0.3194 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0261 | 0.5 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0038 | 0.0285 | 0.028 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0031 | 0.0207 | 0.0229 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.0385 | 0.0902 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0125 | 0.0118 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0207 | 0.2408 | 0.651 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.0615 | 0.0608 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0046 | 0.0385 | 0.038 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.1364 | 0.3211 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0615 | 0.1442 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0085 | 0.0883 | 0.2512 |
Brugia malayi | CHD4 protein | 0.0028 | 0.0169 | 0.0274 |
Entamoeba histolytica | 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein | 0.0044 | 0.0359 | 0.0655 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0385 | 0.0378 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0261 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0309 | 0.3699 | 0.3695 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0125 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0385 | 0.0378 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.11 | 0.2728 |
Loa Loa (eye worm) | carboxylesterase | 0.0046 | 0.0385 | 0.0378 |
Echinococcus granulosus | acetylcholinesterase | 0.027 | 0.3199 | 0.5406 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0044 | 0.0359 | 0.0655 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0207 | 0.2408 | 0.6388 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0207 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0125 | 0.0118 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0207 | 0.2408 | 0.6388 |
Echinococcus granulosus | carboxylesterase 5A | 0.027 | 0.3199 | 0.5406 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0253 | 0.0247 |
Schistosoma mansoni | chromobox protein | 0.0025 | 0.0125 | 0.0294 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0261 | 0.0378 |
Trichomonas vaginalis | conserved hypothetical protein | 0.006 | 0.0571 | 0.1247 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0207 | 0.0229 |
Onchocerca volvulus | 0.0046 | 0.0385 | 0.086 | |
Schistosoma mansoni | chromobox protein | 0.0025 | 0.0125 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0359 | 0.0352 |
Trichomonas vaginalis | conserved hypothetical protein | 0.006 | 0.0571 | 0.1247 |
Brugia malayi | Carboxylesterase family protein | 0.027 | 0.3199 | 0.5406 |
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.0359 | 1 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0025 | 0.0125 | 0.0294 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0041 | 0.0329 | 0.0322 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0207 | 0.2408 | 0.651 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0051 | 0.0453 | 0.0754 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0385 | 0.0378 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0174 | 0.0283 |
Loa Loa (eye worm) | carboxylesterase | 0.0046 | 0.0385 | 0.0378 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0207 | 0.0229 |
Echinococcus multilocularis | geminin | 0.0355 | 0.4265 | 0.4283 |
Schistosoma mansoni | hypothetical protein | 0.0355 | 0.4265 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.0359 | 0.0655 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0029 | 0.0022 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.0093 | 0.0086 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.0309 | 0.3699 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0428 | 0.0421 |
Brugia malayi | RNA binding protein | 0.0064 | 0.0615 | 0.1029 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0073 | 0.0111 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0203 | 0.0476 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0044 | 0.0359 | 0.0655 |
Echinococcus multilocularis | chromobox protein 1 | 0.0152 | 0.1723 | 0.1726 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0964 | 0.2259 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0312 | 0.0305 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0261 | 0.0378 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.0542 | 0.1166 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0048 | 0.0416 | 0.0974 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0073 | 0.0066 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0309 | 0.3699 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0356 | 0.0591 |
Echinococcus granulosus | muscleblind protein | 0.015 | 0.1693 | 0.2856 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0125 | 0.0118 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.013 | 0.0013 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0099 | 0.1056 | 0.1777 |
Echinococcus multilocularis | chromobox protein 2 | 0.0025 | 0.0125 | 0.0119 |
Echinococcus multilocularis | muscleblind protein | 0.015 | 0.1693 | 0.1696 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0041 | 0.0329 | 0.0772 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0123 | 0.1364 | 0.2298 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0218 | 0.0511 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.0203 | 0.0197 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.0309 | 0.3699 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0233 | 0.274 | 0.4628 |
Echinococcus granulosus | Chromo domain | 0.0025 | 0.0125 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0261 | 0.0253 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0044 | 0.0359 | 0.0655 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0125 | 0.0118 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0044 | 0.0359 | 0.0842 |
Brugia malayi | Protein cec-1. | 0.0025 | 0.0125 | 0.02 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0028 | 0.0169 | 0.0274 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0448 | 0.0441 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0041 | 0.0329 | 0.0545 |
Trichomonas vaginalis | chromobox protein, putative | 0.0092 | 0.0965 | 0.2349 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.1693 | 0.1687 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0073 | 0.0171 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0385 | 0.0639 |
Brugia malayi | hypothetical protein | 0.0025 | 0.013 | 0.0208 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0051 | 0.0453 | 0.1223 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0615 | 0.1442 |
Echinococcus multilocularis | acetylcholinesterase | 0.027 | 0.3199 | 0.321 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.013 | 0.0351 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.3199 | 0.3194 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.013 | 0.0351 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0152 | 0.1723 | 0.1717 |
Schistosoma mansoni | gliotactin | 0.0046 | 0.0385 | 0.0902 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0359 | 0.0655 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0207 | 0.0229 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0232 | 0.2726 | 0.2734 |
Giardia lamblia | Kinase, PLK | 0.0207 | 0.2408 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0203 | 0.0218 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0085 | 0.0883 | 0.2121 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0207 | 0.0229 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0025 | 0.0125 | 0.0294 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0486 | 0.5911 | 0.5938 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0123 | 0.1364 | 0.3465 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.0359 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.027 | 0.3199 | 0.3194 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0123 | 0.1364 | 0.3197 |
Echinococcus granulosus | chromobox protein 2 | 0.0025 | 0.0125 | 0.02 |
Brugia malayi | hypothetical protein | 0.0486 | 0.5911 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0355 | 0.4265 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0261 | 0.0429 |
Brugia malayi | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 0.0309 | 0.3699 | 0.6254 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0309 | 0.3699 | 1 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0025 | 0.0125 | 0.02 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0261 | 0.0378 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0309 | 0.3699 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0152 | 0.1723 | 0.2906 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0679 | 0.0672 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0203 | 0.0332 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0232 | 0.2726 | 0.272 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0359 | 0.0655 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0261 | 0.0429 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0239 | 0.0561 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0261 | 0.0611 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.1836 | 0.183 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0385 | 0.0378 |
Echinococcus multilocularis | chromobox protein 1 | 0.0152 | 0.1723 | 0.1726 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0123 | 0.1364 | 0.3197 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0207 | 0.2408 | 0.6388 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.0359 | 0.0971 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0092 | 0.0965 | 0.2782 |
Loa Loa (eye worm) | carboxylesterase | 0.027 | 0.3199 | 0.3194 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0261 | 0.0253 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0239 | 0.0233 |
Onchocerca volvulus | 0.0046 | 0.0385 | 0.086 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0253 | 0.0416 |
Onchocerca volvulus | 0.0029 | 0.0174 | 0.0162 | |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0025 | 0.0125 | 0.02 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0309 | 0.3699 | 1 |
Onchocerca volvulus | 0.0046 | 0.0385 | 0.086 | |
Onchocerca volvulus | 0.0046 | 0.0385 | 0.086 | |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.0044 | 0.0359 | 0.0596 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0051 | 0.0453 | 0.0448 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.0453 | 0.1061 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.0232 | 0.2726 | 0.4605 |
Trichomonas vaginalis | chromobox protein, putative | 0.0152 | 0.1723 | 0.447 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0207 | 0.2408 | 0.7566 |
Onchocerca volvulus | 0.0036 | 0.0261 | 0.0448 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0051 | 0.0448 | 0.1051 |
Echinococcus granulosus | geminin | 0.0355 | 0.4265 | 0.7213 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.0615 | 0.1029 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0051 | 0.0453 | 0.1223 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0261 | 0.0704 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0385 | 0.0378 |
Trichomonas vaginalis | set domain proteins, putative | 0.0265 | 0.3143 | 0.8443 |
Echinococcus granulosus | single minded 2 | 0.0036 | 0.0259 | 0.0426 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0046 | 0.0385 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0261 | 0.0253 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0021 | 0.0014 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0595 | 0.1395 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.0044 | 0.0359 | 0.0596 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0046 | 0.0385 | 0.0902 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0207 | 0.2408 | 0.6388 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0261 | 0.0429 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0123 | 0.1364 | 0.457 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0031 | 0.0207 | 0.0229 |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.0044 | 0.0359 | 0.0708 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.0615 | 0.1029 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0.0203 | 0.3324 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.0964 | 0.0962 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0051 | 0.0453 | 0.0448 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.013 | 0.0351 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.0615 | 0.0608 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0261 | 0.0005 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0028 | 0.0169 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0261 | 0.0253 |
Brugia malayi | hypoxia-induced factor 1 | 0.0149 | 0.1679 | 0.2832 |
Mycobacterium ulcerans | hypothetical protein | 0.0309 | 0.3699 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0261 | 0.0253 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0453 | 0.0916 |
Onchocerca volvulus | 0.0036 | 0.0261 | 0.0448 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0203 | 0.3324 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0309 | 0.3699 | 1 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.0044 | 0.0359 | 0.0354 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.1364 | 0.3211 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.1364 | 0.3211 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.0964 | 0.162 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0261 | 0.0253 |
Onchocerca volvulus | 0.0036 | 0.0259 | 0.0443 | |
Onchocerca volvulus | 0.0099 | 0.1056 | 0.3086 | |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0261 | 0.0255 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0102 | 0.1091 | 0.1091 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0025 | 0.0125 | 0.02 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0453 | 0.0916 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0615 | 0.1442 |
Echinococcus granulosus | neuroligin | 0.0046 | 0.0385 | 0.0639 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0207 | 0.2408 | 0.6388 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0807 | 0.9949 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0385 | 0.0639 |
Brugia malayi | PAS domain containing protein | 0.0048 | 0.0416 | 0.0692 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0218 | 0.0212 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0051 | 0.0453 | 0.1223 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.0964 | 0.162 |
Brugia malayi | Valyl-tRNA synthetase | 0.0025 | 0.0125 | 0.02 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.013 | 0.02 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0261 | 0.0378 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0138 | 0.0222 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0149 | 0.1679 | 0.1673 |
Trichomonas vaginalis | chromobox protein, putative | 0.0152 | 0.1723 | 0.447 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0232 | 0.2726 | 0.639 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0261 | 0.0253 |
Echinococcus multilocularis | Chromo domain | 0.0025 | 0.0125 | 0.0119 |
Brugia malayi | jmjC domain containing protein | 0.0102 | 0.1091 | 0.1836 |
Brugia malayi | Muscleblind-like protein | 0.015 | 0.1693 | 0.2856 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0261 | 0.0253 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.013 | 0.02 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0109 | 0.0103 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0051 | 0.0448 | 0.1051 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0233 | 0.0226 |
Echinococcus multilocularis | muscleblind protein 1 | 0.015 | 0.1693 | 0.1696 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.0615 | 0.1029 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0239 | 0.4869 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0017 | 0.0017 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0051 | 0.0453 | 0.0754 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0356 | 0.0351 |
Brugia malayi | chromobox protein homolog 3 | 0.0085 | 0.0883 | 0.1484 |
Brugia malayi | SET domain containing protein | 0.0027 | 0.0149 | 0.0239 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0007 | 0.0017 |
Onchocerca volvulus | Alhambra homolog | 0.0031 | 0.0203 | 0.0258 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0218 | 0.0357 |
Echinococcus multilocularis | carboxylesterase 5A | 0.027 | 0.3199 | 0.321 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0028 | 0.0169 | 0.0163 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0203 | 0.0218 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0007 | 0.0017 |
Onchocerca volvulus | 0.0067 | 0.0652 | 0.1746 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0453 | 0.0916 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0109 | 0.0256 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0239 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0385 | 0.0378 |
Brugia malayi | Carboxylesterase family protein | 0.027 | 0.3199 | 0.5406 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0216 | 0.0353 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.0608 | 0.1426 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0261 | 0.0704 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0239 | 0.0393 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 0 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 0 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 9.64 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 9.75 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 11.73 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 33 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 97 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition frequency index (IFI) (functional) | = 2.7 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
Percent growth inhibition (functional) | = -4 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = -2 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 33 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 97 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
XC50 (functional) | = 6.2 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
XC50 (functional) | = 0.6277 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.