Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | steroid hormone receptor | 0.0793 | 0.5589 | 0.9609 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0182 | 0.1124 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0356 | 0.2396 | 0.2341 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.056 | 0.1123 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.056 | 0.0904 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0157 | 0.0937 | 0.1414 |
Loa Loa (eye worm) | phosphofructokinase | 0.0105 | 0.056 | 0.0904 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0038 | 0.0073 | 0.5248 |
Brugia malayi | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0443 | 0.0702 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1023 | 0.0958 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0356 | 0.2396 | 0.4083 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0284 | 0.1864 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0176 | 0.1078 | 0.18 |
Trichomonas vaginalis | CAMK family protein kinase | 0.014 | 0.0818 | 0.164 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0847 | 0.14 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.056 | 0.3003 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0356 | 0.2396 | 0.2341 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0275 | 0.124 |
Echinococcus granulosus | muscleblind protein | 0.0176 | 0.1078 | 0.1013 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0228 | 0.1461 | 0.14 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Loa Loa (eye worm) | hypothetical protein | 0.0176 | 0.1078 | 0.18 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.056 | 0.3003 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0047 | 0.0139 | 0.0932 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0275 | 0.124 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.014 | 0.0814 | 0.4058 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0038 | 0.0073 | 0.0061 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0295 | 0.1951 | 1 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0124 | 0.0699 | 0.0632 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0264 | 0.0391 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.056 | 0.0904 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0436 | 0.298 | 0.5093 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.0802 | 0.0736 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0436 | 0.298 | 0.2929 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0124 | 0.0699 | 0.6091 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.094 | 0.1561 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0284 | 0.1864 | 0.9544 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.009 | 0.0447 | 0.0378 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0284 | 0.1864 | 0.3046 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.0211 | 0.03 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0204 | 0.1282 | 0.2153 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.1864 | 0.3738 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0284 | 0.1864 | 0.1805 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0105 | 0.056 | 0.0492 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.056 | 0.1123 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Brugia malayi | nuclear receptor NHR-67 | 0.0157 | 0.0937 | 0.1556 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0078 | 0.0361 | 0.1687 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.02 | 0.1252 | 0.2102 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0157 | 0.094 | 0.0874 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0356 | 0.2396 | 0.4083 |
Brugia malayi | conserved hypotetical protein | 0.0157 | 0.0937 | 0.1556 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1397 | 1 | 1 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0105 | 0.056 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.0264 | 0.0194 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0038 | 0.0073 | 0.0184 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0356 | 0.2396 | 0.2341 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0295 | 0.1951 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0228 | 0.1461 | 0.14 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0057 | 0.0211 | 0.03 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.0211 | 0.0141 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0047 | 0.0139 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.1864 | 0.3738 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0108 | 0.0585 | 0.0947 |
Brugia malayi | nuclear receptor NHR-88 | 0.0356 | 0.2396 | 0.4083 |
Echinococcus multilocularis | GPCR, family 2 | 0.0064 | 0.0264 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0047 | 0.0139 | 0.3109 |
Brugia malayi | chromobox protein homolog 3 | 0.0081 | 0.0381 | 0.0594 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0356 | 0.2396 | 0.2341 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0356 | 0.2396 | 0.4083 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.009 | 0.0447 | 0.0378 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0138 | 0.0802 | 0.0736 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0182 | 0.1124 | 0.106 |
Trichomonas vaginalis | chromobox protein, putative | 0.0087 | 0.0426 | 0.0854 |
Schistosoma mansoni | ap endonuclease | 0.0038 | 0.0073 | 0.0001 |
Loa Loa (eye worm) | pip kinase 2 | 0.0157 | 0.094 | 0.1561 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0078 | 0.0361 | 0.1687 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0356 | 0.2396 | 0.2341 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0064 | 0.0264 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1252 | 0.2102 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.0264 | 0.0194 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0072 | 0.0059 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0038 | 0.0073 | 0.0001 |
Brugia malayi | hypothetical protein | 0.02 | 0.1252 | 0.2102 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0045 | 0.0121 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0275 | 0.124 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.056 | 0.1123 |
Trichomonas vaginalis | chromobox protein, putative | 0.0087 | 0.0426 | 0.0854 |
Brugia malayi | hypothetical protein | 0.0089 | 0.0443 | 0.0702 |
Brugia malayi | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0078 | 0.0361 | 0.1687 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0356 | 0.2396 | 0.4083 |
Loa Loa (eye worm) | hypothetical protein | 0.0176 | 0.1078 | 0.18 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0066 | 0.0275 | 0.124 |
Echinococcus granulosus | FTZ F1 alpha | 0.0733 | 0.5145 | 0.511 |
Brugia malayi | steroid hormone receptor | 0.0793 | 0.5589 | 0.9609 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0138 | 0.0802 | 0.1323 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0157 | 0.0937 | 0.0871 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Brugia malayi | tailless protein | 0.0157 | 0.0937 | 0.1556 |
Brugia malayi | Heterochromatin protein 1 | 0.0144 | 0.0842 | 0.1392 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0356 | 0.2396 | 0.2341 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0204 | 0.1282 | 0.2153 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0038 | 0.0073 | 0.1631 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0096 | 0.0305 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0436 | 0.298 | 0.5093 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0182 | 0.1124 | 0.5677 |
Echinococcus multilocularis | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0157 | 0.094 | 0.0874 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0096 | 0.0305 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0275 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.017 | 0.023 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0138 | 0.0802 | 0.0736 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0356 | 0.2396 | 0.3983 |
Onchocerca volvulus | 0.0052 | 0.017 | 0.0066 | |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0284 | 0.1864 | 0.9544 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0047 | 0.0139 | 0.0629 |
Onchocerca volvulus | 0.0169 | 0.1024 | 0.1568 | |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0124 | 0.0699 | 0.1145 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.009 | 0.0447 | 0.0378 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0157 | 0.0937 | 0.1556 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0072 | 0.0384 |
Trichomonas vaginalis | set domain proteins, putative | 0.0711 | 0.4986 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.0802 | 0.0736 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0284 | 0.1864 | 0.3161 |
Echinococcus multilocularis | tumor protein p63 | 0.0353 | 0.2373 | 0.2318 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0139 | 0.0811 | 0.1338 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0078 | 0.0361 | 0.0559 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0275 | 0.124 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0436 | 0.298 | 0.2929 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0356 | 0.2396 | 0.4083 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.056 | 0.1123 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0052 | 0.017 | 0.0099 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0038 | 0.0073 | 0.0391 |
Schistosoma mansoni | chromobox protein | 0.0144 | 0.0842 | 0.0776 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0254 | 0.0374 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0264 | 0.0194 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0047 | 0.0139 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0353 | 0.2373 | 0.2318 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0038 | 0.0073 | 0.0391 |
Onchocerca volvulus | 0.0157 | 0.0937 | 0.1414 | |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0047 | 0.0139 | 0.1237 |
Echinococcus granulosus | geminin | 0.0168 | 0.1023 | 0.0958 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0138 | 0.0802 | 0.1323 |
Brugia malayi | hypothetical protein | 0.0228 | 0.1461 | 0.2464 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0133 | 0.0165 |
Schistosoma mansoni | thyroid hormone receptor | 0.0356 | 0.2396 | 0.2341 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0847 | 0.14 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0356 | 0.2396 | 0.2341 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0182 | 0.1124 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0356 | 0.2396 | 0.2341 |
Entamoeba histolytica | hypothetical protein | 0.0047 | 0.0139 | 0.0746 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0144 | 0.0842 | 0.1392 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0078 | 0.0361 | 0.0291 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0038 | 0.0073 | 0.1303 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0052 | 0.0172 | 0.0701 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0275 | 0.124 |
Brugia malayi | ecdysteroid receptor | 0.0824 | 0.5815 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0356 | 0.2396 | 0.4083 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Schistosoma mansoni | thyroid hormone receptor | 0.0356 | 0.2396 | 0.2341 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.02 | 0.1252 | 0.1189 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0356 | 0.2396 | 0.4083 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.1864 | 0.3738 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0955 | 0.6768 | 0.6745 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0047 | 0.0139 | 1 |
Onchocerca volvulus | 0.0711 | 0.4986 | 0.8542 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0141 | 0.082 | 0.1354 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0295 | 0.1951 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0436 | 0.298 | 0.5093 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1252 | 0.2102 |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.2396 | 0.4083 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.056 | 0.0904 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0594 | 0.4129 | 0.4087 |
Brugia malayi | Cytochrome P450 family protein | 0.0101 | 0.0528 | 0.0848 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0047 | 0.0139 | 0.2484 |
Brugia malayi | Pre-SET motif family protein | 0.0625 | 0.4356 | 0.7475 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.009 | 0.0447 | 0.0378 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0087 | 0.0426 | 0.0515 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0356 | 0.2396 | 0.2341 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.056 | 0.0904 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0157 | 0.094 | 0.0874 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0078 | 0.0361 | 0.0559 |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.2396 | 0.4083 |
Onchocerca volvulus | Huntingtin homolog | 0.0144 | 0.0847 | 0.1256 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.02 | 0.1252 | 0.2102 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0356 | 0.2396 | 0.4083 |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.2396 | 0.4083 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0295 | 0.1951 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0141 | 0.082 | 0.1354 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0356 | 0.2396 | 0.2341 |
Schistosoma mansoni | eyes absent homolog | 0.0089 | 0.0443 | 0.0374 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Onchocerca volvulus | 0.0063 | 0.0254 | 0.0213 | |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.056 | 0.0492 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0086 | 0.0423 | 0.0354 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0157 | 0.0937 | 0.1556 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0356 | 0.2396 | 0.4083 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0356 | 0.2396 | 0.3983 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0625 | 0.4356 | 0.7475 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0157 | 0.0937 | 0.0871 |
Schistosoma mansoni | nuclear receptor | 0.0157 | 0.0937 | 0.0871 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0811 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1252 | 0.2102 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0157 | 0.0937 | 0.0871 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0096 | 0.0305 |
Mycobacterium ulcerans | hypothetical protein | 0.0156 | 0.093 | 0.821 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0038 | 0.0073 | 0.0001 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0064 | 0.0264 | 0.0391 |
Brugia malayi | nuclear hormone receptor | 0.0157 | 0.0937 | 0.1556 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.056 | 0.2728 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0157 | 0.0937 | 0.1556 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0157 | 0.0937 | 0.1556 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.009 | 0.0447 | 0.0378 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0284 | 0.1864 | 0.3161 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.0811 | 0.0744 |
Brugia malayi | Pip kinase protein 2 | 0.0157 | 0.094 | 0.1561 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0356 | 0.2396 | 0.2341 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0057 | 0.0211 | 0.0141 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.009 | 0.0447 | 0.3979 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0284 | 0.1864 | 0.1805 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.02 | 0.1252 | 0.1189 |
Plasmodium vivax | SET domain protein, putative | 0.009 | 0.0447 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0356 | 0.2396 | 0.2341 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0157 | 0.0937 | 0.0871 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.0376 | 0.0307 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.009 | 0.0447 | 0.0378 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1397 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0157 | 0.0937 | 0.1556 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0182 | 0.1124 | 0.106 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0356 | 0.2396 | 0.4083 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0169 | 0.1024 | 0.0959 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0356 | 0.2396 | 0.4083 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.0814 | 0.4058 |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.2396 | 0.4083 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0182 | 0.1124 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0133 | 0.0062 |
Schistosoma mansoni | coup transcription factor | 0.0356 | 0.2396 | 0.2341 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0038 | 0.0073 | 0.0184 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0157 | 0.0937 | 0.1556 |
Schistosoma mansoni | nuclear hormone receptor | 0.0356 | 0.2396 | 0.2341 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0096 | 0.0305 |
Echinococcus granulosus | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0157 | 0.094 | 0.0874 |
Brugia malayi | hypothetical protein | 0.015 | 0.089 | 0.1475 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0038 | 0.0073 | 0.0184 |
Trypanosoma brucei | polo-like protein kinase | 0.0284 | 0.1864 | 0.9544 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.02 | 0.1252 | 0.1189 |
Trichomonas vaginalis | CAMK family protein kinase | 0.014 | 0.0818 | 0.164 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0078 | 0.0361 | 0.1935 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0047 | 0.0139 | 0.0932 |
Echinococcus multilocularis | muscleblind protein | 0.0176 | 0.1078 | 0.1013 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0156 | 0.093 | 0.815 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0284 | 0.1864 | 0.9544 |
Schistosoma mansoni | kinase | 0.0144 | 0.0845 | 0.0779 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0045 | 0.0121 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.1461 | 0.2464 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0356 | 0.2396 | 0.2341 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0047 | 0.0139 | 0.0529 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.1864 | 0.3738 |
Brugia malayi | ecdysone receptor | 0.0157 | 0.0937 | 0.1556 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0064 | 0.0264 | 0.0391 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0078 | 0.0361 | 0.1687 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0381 | 0.0594 |
Schistosoma mansoni | nuclear receptor | 0.0157 | 0.0937 | 0.0871 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.056 | 0.2728 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0038 | 0.0073 | 0.0146 |
Brugia malayi | nuclear hormone receptor | 0.0356 | 0.2396 | 0.4083 |
Giardia lamblia | Kinase, PLK | 0.0284 | 0.1864 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0101 | 0.0528 | 0.0848 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Onchocerca volvulus | 0.015 | 0.089 | 0.1332 | |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0182 | 0.1124 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0081 | 0.0381 | 0.0436 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0356 | 0.2396 | 0.4083 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0105 | 0.056 | 1 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0124 | 0.0699 | 0.0632 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.0264 | 0.0194 |
Onchocerca volvulus | 0.0157 | 0.094 | 0.142 | |
Echinococcus granulosus | 6 phosphofructokinase | 0.0105 | 0.056 | 0.0492 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0141 | 0.082 | 0.1354 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0141 | 0.1253 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0436 | 0.298 | 0.2929 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0157 | 0.0937 | 0.1556 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0163 | 0.0652 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0356 | 0.2396 | 0.4083 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0284 | 0.1864 | 0.1805 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0157 | 0.0937 | 0.0871 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0182 | 0.1124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1252 | 0.2102 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0182 | 0.1124 | 0.106 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0356 | 0.2396 | 0.4083 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0057 | 0.0209 | 0.042 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0356 | 0.2396 | 0.4083 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0356 | 0.2396 | 0.2341 |
Schistosoma mansoni | ap endonuclease | 0.0038 | 0.0073 | 0.0001 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.1864 | 0.3738 |
Brugia malayi | nuclear receptor NHR-88 | 0.0157 | 0.0937 | 0.1556 |
Echinococcus granulosus | chromobox protein 1 | 0.0144 | 0.0842 | 0.0776 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.089 | 0.1475 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.0211 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0443 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.2396 | 0.4083 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0057 | 0.0211 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0447 | 0.0709 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0169 | 0.1024 | 0.0959 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0356 | 0.2396 | 0.4083 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0057 | 0.0209 | 0.042 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.0802 | 0.0736 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0157 | 0.0937 | 0.0871 |
Echinococcus granulosus | chromobox protein 1 | 0.0144 | 0.0842 | 0.0776 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0169 | 0.1024 | 0.1707 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0356 | 0.2396 | 0.4083 |
Brugia malayi | hypothetical protein | 0.0144 | 0.0847 | 0.14 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0038 | 0.0073 | 0.0324 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0824 | 0.5815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0824 | 0.5815 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.0264 | 0.0194 |
Schistosoma mansoni | chromobox protein | 0.0144 | 0.0842 | 0.0776 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.056 | 0.0492 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0124 | 0.0699 | 0.0632 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.1864 | 0.3738 |
Toxoplasma gondii | exonuclease III APE | 0.0038 | 0.0073 | 0.0649 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0157 | 0.0937 | 0.0871 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0204 | 0.1282 | 0.2153 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0057 | 0.0211 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1252 | 0.2102 |
Brugia malayi | phosphofructokinase | 0.0105 | 0.056 | 0.0904 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0356 | 0.2396 | 0.4083 |
Echinococcus multilocularis | chromobox protein 1 | 0.0144 | 0.0842 | 0.0776 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0057 | 0.0211 | 0.0141 |
Onchocerca volvulus | 0.0113 | 0.0619 | 0.0855 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0081 | 0.0381 | 0.0764 |
Onchocerca volvulus | 0.0356 | 0.2396 | 0.3983 | |
Brugia malayi | Nuclear hormone receptor E75 | 0.0157 | 0.0937 | 0.1556 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0138 | 0.0802 | 0.0736 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0264 | 0.0194 |
Schistosoma mansoni | zinc finger protein | 0.0157 | 0.0937 | 0.0871 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0138 | 0.0802 | 0.0736 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0264 | 0.0194 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0157 | 0.0937 | 0.0871 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0133 | 0.0062 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.02 | 0.1252 | 0.1189 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0105 | 0.056 | 0.2728 |
Brugia malayi | nuclear receptor RXR | 0.02 | 0.1252 | 0.2102 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0113 | 0.0619 | 0.0551 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0356 | 0.2396 | 0.2341 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0275 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.1282 | 0.2153 |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.2396 | 0.4083 |
Echinococcus multilocularis | geminin | 0.0168 | 0.1023 | 0.0958 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0176 | 0.1078 | 0.1013 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0124 | 0.0699 | 0.3458 |
Brugia malayi | nuclear receptor RXR | 0.0157 | 0.0937 | 0.1556 |
Loa Loa (eye worm) | DR-78 | 0.0157 | 0.0937 | 0.1556 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.006 | 0.0233 | 0.1021 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0072 | 0.0384 |
Echinococcus granulosus | GPCR family 2 | 0.0064 | 0.0264 | 0.0194 |
Onchocerca volvulus | 0.0157 | 0.0937 | 0.1414 | |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0157 | 0.0937 | 0.0871 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0078 | 0.0361 | 0.0291 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0078 | 0.0361 | 0.0291 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0157 | 0.0937 | 0.1414 |
Brugia malayi | Pre-SET motif family protein | 0.009 | 0.0447 | 0.0709 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0157 | 0.0937 | 0.0871 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0124 | 0.0699 | 0.6091 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0356 | 0.2396 | 0.2341 |
Schistosoma mansoni | jumonji domain containing protein | 0.0057 | 0.0211 | 0.0141 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0356 | 0.2396 | 0.2341 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0105 | 0.056 | 0.4805 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.056 | 0.3003 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0356 | 0.2396 | 0.2341 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0937 | 0.1556 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0072 | 0.0384 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0081 | 0.0381 | 0.0764 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0047 | 0.0139 | 0.1237 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0105 | 0.056 | 0.4632 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1023 | 0.0958 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0072 | 0.0384 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0356 | 0.2396 | 0.2341 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0356 | 0.2396 | 0.4083 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0038 | 0.0073 | 0.0184 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.0814 | 0.4058 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1024 | 0.1707 |
Echinococcus multilocularis | chromobox protein 1 | 0.0144 | 0.0842 | 0.0776 |
Brugia malayi | hypothetical protein | 0.02 | 0.1252 | 0.2102 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.02 | 0.1252 | 0.2102 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0047 | 0.0139 | 0.0529 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0264 | 0.0194 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0157 | 0.0937 | 0.0871 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0157 | 0.0937 | 0.0871 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0038 | 0.0073 | 0.0061 |
Trichomonas vaginalis | chromobox protein, putative | 0.0144 | 0.0842 | 0.1689 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0038 | 0.0073 | 0.0146 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0356 | 0.2396 | 0.4083 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0356 | 0.2396 | 0.2341 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0436 | 0.298 | 0.2929 |
Schistosoma mansoni | nuclear hormone receptor | 0.0157 | 0.0937 | 0.0871 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0356 | 0.2396 | 0.2341 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0157 | 0.0937 | 0.0871 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0356 | 0.2396 | 0.2341 |
Onchocerca volvulus | Huntingtin homolog | 0.0144 | 0.0847 | 0.1256 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0124 | 0.0699 | 0.596 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0356 | 0.2396 | 0.4083 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.0211 | 0.0141 |
Schistosoma mansoni | nuclear hormone receptor | 0.0157 | 0.0937 | 0.0871 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0157 | 0.0937 | 0.1556 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.1864 | 0.3738 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0169 | 0.1024 | 0.0959 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0182 | 0.1124 | 0.106 |
Trichomonas vaginalis | chromobox protein, putative | 0.0144 | 0.0842 | 0.1689 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0157 | 0.0937 | 0.0871 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition frequency index (IFI) (functional) | = 14.08 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
Percent growth inhibition (functional) | = -7 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 95 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 99 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 100 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
XC50 (functional) | = 6.15 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.