Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.003 | 0.003 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.003 | 0.0063 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.003 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0155 | 0.0327 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0109 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0111 | 0.0235 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0033 | 0.0089 | 0.0188 |
Onchocerca volvulus | 0.0036 | 0.0104 | 0.0221 | |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0104 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.031 | 0.0655 |
Brugia malayi | Pre-SET motif family protein | 0.0874 | 0.4148 | 0.8765 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0104 | 0.0952 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0104 | 0.4425 |
Brugia malayi | intermediate filament protein | 0.017 | 0.0751 | 0.1587 |
Schistosoma mansoni | smad | 0.0033 | 0.0089 | 0.0089 |
Onchocerca volvulus | 0.0036 | 0.0104 | 0.0221 | |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0024 | 0.0046 | 0.0122 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0104 | 0.1887 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0008 | 0.0018 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0234 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0058 | 0.0208 | 0.886 |
Schistosoma mansoni | ferritin | 0.0026 | 0.0055 | 0.0055 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0104 | 0.0202 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.003 | 0.003 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.0017 | 0.0036 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.003 | 0.1215 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0024 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0615 | 0.1299 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.003 | 0.0063 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0144 | 0.0621 | 0.1312 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.003 | 0.0063 |
Echinococcus multilocularis | expressed protein | 0.0026 | 0.0055 | 0.0055 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0104 | 0.0952 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Trichomonas vaginalis | chaperonin, putative | 0.0024 | 0.0046 | 0.0079 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0104 | 0.4425 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0234 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0387 | 0.0387 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0145 | 0.0627 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0104 | 0.0202 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.003 | 0.0063 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0234 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.003 | 0.003 |
Echinococcus multilocularis | lamin | 0.017 | 0.0751 | 0.0751 |
Schistosoma mansoni | tar DNA-binding protein | 0.0995 | 0.4733 | 0.4733 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0047 | 0.0155 | 0.1432 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.003 | 0.0063 |
Onchocerca volvulus | 0.0125 | 0.0533 | 0.1128 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0104 | 0.0203 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.003 | 0.003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1358 | 0.2858 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0104 | 0.4404 |
Schistosoma mansoni | hypothetical protein | 0.031 | 0.1425 | 0.1425 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1358 | 0.2858 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.003 | 0.0474 |
Onchocerca volvulus | Cathepsin F homolog | 0.0017 | 0.0008 | 0.0018 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0033 | 0.0089 | 0.0089 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0135 | 0.0581 | 0.0581 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0144 | 0.0621 | 0.0621 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0008 | 0.0008 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0109 | 0.1974 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.005 | 0.0169 | 0.7188 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0008 | 0.031 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0022 | 0.0022 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0621 | 0.0621 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0109 | 0.0213 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0319 | 0.0319 |
Onchocerca volvulus | 0.0021 | 0.003 | 0.0063 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.0387 | 0.0387 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.001 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0081 | 0.0319 | 0.0319 |
Onchocerca volvulus | 0.0095 | 0.0386 | 0.0816 | |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.017 | 0.0751 | 0.1587 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0047 | 0.0155 | 0.1742 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0008 | 0.0075 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.003 | 0.0045 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.2086 | 1 | 1 |
Onchocerca volvulus | 0.017 | 0.0751 | 0.1587 | |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0008 | 0.0018 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.003 | 0.0063 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0155 | 0.659 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0296 | 0.1358 | 1 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0024 | 0.0046 | 0.0781 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0097 | 0.0206 |
Echinococcus multilocularis | Smad4 | 0.0033 | 0.0089 | 0.0089 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.003 | 0.003 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0454 | 0.2118 | 0.4476 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0145 | 0.0627 | 0.5931 |
Schistosoma mansoni | alpha-glucosidase | 0.0141 | 0.061 | 0.061 |
Echinococcus multilocularis | ferritin | 0.0026 | 0.0055 | 0.0055 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0135 | 0.0581 | 0.0581 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0047 | 0.0155 | 0.1742 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0155 | 0.1742 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0081 | 0.0319 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0097 | 0.0206 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0766 | 0.3629 | 0.3629 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0024 | 0.0046 | 0.0781 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0109 | 0.023 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0066 | 0.1161 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0104 | 0.0203 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0319 | 0.2298 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0091 | 0.0369 | 0.0779 |
Schistosoma mansoni | hypothetical protein | 0.0156 | 0.0683 | 0.0683 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0387 | 0.0387 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.0155 | 0.1742 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.004 | 0.0066 |
Loa Loa (eye worm) | TAR-binding protein | 0.0995 | 0.4733 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0109 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0104 | 0.022 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0104 | 0.0202 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0766 | 0.3629 | 0.3629 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0155 | 0.1742 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.0887 | 0.1875 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0035 | 0.0097 | 0.1758 |
Schistosoma mansoni | hypothetical protein | 0.0305 | 0.1399 | 0.1399 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0109 | 0.023 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0144 | 0.0621 | 0.1312 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.0751 | 0.1587 |
Loa Loa (eye worm) | nuclear factor I | 0.0018 | 0.0017 | 0.0036 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0017 | 0.0008 | 0.0429 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0109 | 0.094 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0155 | 0.0327 |
Onchocerca volvulus | 0.0017 | 0.0008 | 0.0018 | |
Brugia malayi | beta-lactamase | 0.0036 | 0.0104 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0266 | 0.0562 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.003 | 0.0063 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.003 | 0.0063 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0164 | 0.072 | 0.072 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0454 | 0.2118 | 0.4476 |
Loa Loa (eye worm) | hypothetical protein | 0.0766 | 0.3629 | 0.7668 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0008 | 0.0018 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0005 | 0.0139 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0008 | 0.0018 |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.0008 | 0.0018 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0104 | 0.0952 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0874 | 0.4148 | 0.8765 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.1425 | 0.3012 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0066 | 0.2776 |
Brugia malayi | MH1 domain containing protein | 0.0033 | 0.0089 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0104 | 0.022 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.003 | 0.0063 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.003 | 0.003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.003 | 0.0063 |
Trichomonas vaginalis | set domain proteins, putative | 0.0995 | 0.4732 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0155 | 0.0327 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0097 | 0.0206 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.032 | 0.0676 |
Echinococcus granulosus | GPCR family 2 | 0.0144 | 0.0621 | 0.0621 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.004 | 0.1658 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.0736 | 0.1555 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0164 | 0.072 | 0.1521 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0063 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0145 | 0.0627 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0155 | 0.1742 |
Schistosoma mansoni | ferritin light chain | 0.0026 | 0.0055 | 0.0055 |
Mycobacterium ulcerans | hypothetical protein | 0.0047 | 0.0155 | 0.1742 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0104 | 0.4404 |
Echinococcus granulosus | tar DNA binding protein | 0.0995 | 0.4733 | 0.4733 |
Schistosoma mansoni | tar DNA-binding protein | 0.0995 | 0.4733 | 0.4733 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0047 | 0.0155 | 0.1432 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0033 | 0.0089 | 0.0188 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0995 | 0.4733 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0008 | 0.0018 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0104 | 0.0202 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0109 | 0.0213 |
Schistosoma mansoni | smad1 5 8 and | 0.0033 | 0.0089 | 0.0089 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0104 | 0.086 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.003 | 0.0063 |
Schistosoma mansoni | apoferritin-2 | 0.0026 | 0.0055 | 0.0055 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.001 | 0.001 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0008 | 0.031 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0234 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.0231 | 0.0231 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.031 | 0.1425 | 0.3012 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0008 | 0.031 |
Brugia malayi | MH2 domain containing protein | 0.0033 | 0.0089 | 0.0188 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0104 | 0.0219 |
Echinococcus multilocularis | musashi | 0.017 | 0.0751 | 0.0751 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0035 | 0.0097 | 1 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.001 | 0.001 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0135 | 0.0581 | 0.0581 |
Schistosoma mansoni | ran | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | thyroid hormone receptor | 0.0156 | 0.0682 | 0.0682 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0104 | 0.0203 |
Schistosoma mansoni | tar DNA-binding protein | 0.0995 | 0.4733 | 0.4733 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1667 | 0.7979 | 0.7979 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.003 | 0.0063 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.001 | 0.001 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0488 | 0.2287 | 0.4832 |
Schistosoma mansoni | survival motor neuron protein | 0.0156 | 0.0683 | 0.0683 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.003 | 0.0063 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0104 | 0.0104 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.003 | 0.0156 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0033 | 0.0089 | 0.0089 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0104 | 0.0203 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0066 | 0.0066 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0066 | 0.1161 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0008 | 0.0018 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0104 | 0.0952 |
Schistosoma mansoni | thyroid hormone receptor | 0.0156 | 0.0682 | 0.0682 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0008 | 0.0018 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0046 | 0.1912 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0621 | 0.0621 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0035 | 0.0097 | 0.074 |
Trichomonas vaginalis | ferritin, putative | 0.0026 | 0.0055 | 0.0099 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0104 | 0.4404 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0164 | 0.072 | 0.072 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.003 | 0.003 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0022 | 0.0022 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0104 | 0.0952 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0104 | 0.0104 |
Onchocerca volvulus | 0.0995 | 0.4732 | 1 | |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0109 | 0.0109 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0104 | 0.0202 |
Brugia malayi | hypothetical protein | 0.0081 | 0.0319 | 0.0674 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0156 | 0.0682 | 0.0682 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.003 | 0.003 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.003 | 0.0474 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0325 | 0.0687 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0142 | 0.0615 | 0.0615 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0082 | 0.0325 | 0.0325 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0008 | 0.0018 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0234 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0104 | 0.0952 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.009 | 0.0608 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0155 | 0.0327 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.003 | 0.0063 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0104 | 0.022 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.003 | 0.0063 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.001 | 0.001 |
Brugia malayi | MH1 domain containing protein | 0.0033 | 0.0089 | 0.0188 |
Loa Loa (eye worm) | Smad1 | 0.0033 | 0.0089 | 0.0188 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0104 | 0.1887 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.003 | 0.1215 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0082 | 0.0325 | 0.0325 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0088 | 0.0798 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.003 | 0.0063 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0008 | 0.031 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0125 | 0.0533 | 0.0533 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 0.1592 | 0.1592 |
Echinococcus granulosus | smad | 0.0033 | 0.0089 | 0.0089 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0305 | 0.1399 | 0.2956 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0144 | 0.0621 | 0.0621 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.003 | 0.0063 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0035 | 0.0097 | 0.0886 |
Schistosoma mansoni | intermediate filament proteins | 0.017 | 0.0751 | 0.0751 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0164 | 0.072 | 0.1521 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0059 | 0.0213 | 0.0213 |
Schistosoma mansoni | microtubule-associated protein tau | 0.2086 | 1 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0155 | 0.659 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0109 | 0.4621 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1358 | 0.2858 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0059 | 0.0213 | 0.0213 |
Echinococcus multilocularis | smad | 0.0033 | 0.0089 | 0.0089 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0047 | 0.0155 | 0.1084 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.001 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0024 | 0.0046 | 0.0079 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.003 | 0.003 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0024 | 0.0046 | 0.4441 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0046 | 0.0046 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0109 | 0.4621 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0097 | 0.0206 |
Schistosoma mansoni | smad1 5 8 and | 0.0033 | 0.0089 | 0.0089 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.0008 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0132 | 0.0279 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0125 | 0.0533 | 0.0533 |
Brugia malayi | Pre-SET motif family protein | 0.0125 | 0.0533 | 0.1127 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0047 | 0.0155 | 0.1742 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.003 | 0.0062 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0046 | 0.0097 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0104 | 0.0219 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0319 | 0.2298 |
Echinococcus granulosus | lamin | 0.017 | 0.0751 | 0.0751 |
Schistosoma mansoni | alpha-glucosidase | 0.0141 | 0.061 | 0.061 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0066 | 0.0066 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0109 | 0.4621 |
Onchocerca volvulus | 0.0017 | 0.0008 | 0.0018 | |
Loa Loa (eye worm) | intermediate filament protein | 0.017 | 0.0751 | 0.1587 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0104 | 0.0203 |
Echinococcus granulosus | expressed protein | 0.0026 | 0.0055 | 0.0055 |
Schistosoma mansoni | ferritin | 0.0026 | 0.0055 | 0.0055 |
Echinococcus granulosus | tumor protein p63 | 0.1357 | 0.6482 | 0.6482 |
Brugia malayi | RNA binding protein | 0.0995 | 0.4733 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.0387 | 0.0817 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0155 | 0.0327 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0104 | 0.4425 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.0155 | 0.1742 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0296 | 0.1358 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0104 | 0.086 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.003 | 0.2695 |
Toxoplasma gondii | cathepsin CPL | 0.0017 | 0.0008 | 0.0075 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0008 | 0.0008 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0104 | 0.0706 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0013 | 0.0027 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0319 | 0.2298 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.003 | 0.0063 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0488 | 0.2287 | 0.4832 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.003 | 0.003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0026 | 0.0055 | 0.0483 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.003 | 0.003 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0155 | 0.659 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0164 | 0.072 | 0.072 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0233 | 0.1054 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0454 | 0.2118 | 0.4476 |
Onchocerca volvulus | 0.0199 | 0.0887 | 0.1876 | |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.031 | 0.0655 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0036 | 0.0036 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0125 | 0.0533 | 0.0533 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0005 | 0.0139 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0319 | 0.2298 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.003 | 0.003 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0104 | 0.0202 |
Brugia malayi | Smad1 | 0.0033 | 0.0089 | 0.0188 |
Onchocerca volvulus | 0.0017 | 0.0008 | 0.0018 | |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0104 | 0.0952 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0046 | 0.0097 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0104 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0063 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0104 | 0.0952 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0063 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0008 | 0.0008 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0104 | 0.0104 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0008 | 0.0008 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0008 | 0.031 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0027 | 0.0027 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0008 | 0.0075 |
Onchocerca volvulus | 0.0017 | 0.0008 | 0.0018 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.003 | 0.0063 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1358 | 0.2858 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0104 | 0.0104 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 0.1592 | 0.1592 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.003 | 0.0063 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0005 | 0.0139 |
Echinococcus granulosus | intermediate filament protein | 0.017 | 0.0751 | 0.0751 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0036 | 0.0036 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0035 | 0.0097 | 0.5 |
Onchocerca volvulus | 0.0036 | 0.0104 | 0.0221 | |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0047 | 0.0155 | 0.1742 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0621 | 0.1312 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.009 | 0.0814 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0109 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0097 | 0.0206 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.0017 | 0.0036 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0005 | 0.0139 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.003 | 0.0063 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.003 | 0.003 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0109 | 0.0109 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0008 | 0.0008 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0111 | 0.0236 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0104 | 0.022 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0046 | 0.1912 |
Onchocerca volvulus | 0.0017 | 0.0008 | 0.0018 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0088 | 0.0798 |
Echinococcus multilocularis | geminin | 0.0345 | 0.1592 | 0.1592 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0104 | 0.0202 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1358 | 0.2858 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.0008 | 0.0018 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.01 | 0.01 |
Plasmodium vivax | SET domain protein, putative | 0.0125 | 0.0533 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.0155 | 0.1084 |
Onchocerca volvulus | 0.0017 | 0.0008 | 0.0018 | |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.004 | 0.0066 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0199 | 0.0887 | 0.0887 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0104 | 0.0706 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0008 | 0.0008 |
Echinococcus granulosus | ferritin | 0.0026 | 0.0055 | 0.0055 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.003 | 0.0063 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0144 | 0.0621 | 0.0621 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0046 | 0.1912 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0296 | 0.1358 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0066 | 0.2776 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0001 | 0.0001 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0621 | 0.0621 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.003 | 0.003 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.003 | 0.0063 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0104 | 0.022 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0104 | 0.0104 |
Brugia malayi | hypothetical protein | 0.0766 | 0.3629 | 0.7668 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0387 | 0.0387 |
Echinococcus granulosus | Smad4 | 0.0033 | 0.0089 | 0.0089 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0005 | 0.0139 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0066 | 0.6606 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0063 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.003 | 0.1215 |
Echinococcus multilocularis | GPCR, family 2 | 0.0144 | 0.0621 | 0.0621 |
Onchocerca volvulus | 0.0047 | 0.0155 | 0.0327 | |
Onchocerca volvulus | 0.0017 | 0.0008 | 0.0018 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0104 | 0.022 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0104 | 0.4425 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0033 | 0.0089 | 0.0089 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0033 | 0.0089 | 0.0089 |
Schistosoma mansoni | apoferritin-2 | 0.0026 | 0.0055 | 0.0055 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0142 | 0.0615 | 0.0615 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0017 | 0.0036 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.003 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0123 | 0.0259 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.003 | 0.003 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0036 | 0.0036 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0091 | 0.0369 | 0.0779 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0104 | 0.022 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.003 | 0.0063 |
Schistosoma mansoni | lamin | 0.017 | 0.0751 | 0.0751 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.004 | 0.0066 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0026 | 0.0055 | 0.0483 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0024 | 0.0046 | 0.0097 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0104 | 0.022 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.003 | 0.003 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0104 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0063 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0104 | 0.0104 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.004 | 0.1658 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0104 | 0.086 |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.0008 | 0.0018 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.0008 | 0.0018 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.0387 | 0.0387 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.003 | 0.003 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.003 | 0.0063 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.003 | 0.003 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0005 | 0.0005 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0142 | 0.0615 | 0.0615 |
Onchocerca volvulus | 0.017 | 0.0751 | 0.1587 | |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0024 | 0.0046 | 0.0276 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0033 | 0.0089 | 0.0089 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0104 | 0.0203 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0109 | 0.0744 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0109 | 0.4621 |
Brugia malayi | TAR-binding protein | 0.0995 | 0.4733 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | lamin | 0.017 | 0.0751 | 0.0751 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0008 | 0.0018 |
Echinococcus multilocularis | snurportin 1 | 0.0305 | 0.1399 | 0.1399 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0104 | 0.0202 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.0155 | 0.1084 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0088 | 0.0798 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0296 | 0.1358 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.01 | 0.01 |
Onchocerca volvulus | 0.0156 | 0.0683 | 0.1444 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0017 | 0.0008 | 0.0429 |
Echinococcus granulosus | lamin dm0 | 0.017 | 0.0751 | 0.0751 |
Brugia malayi | MH2 domain containing protein | 0.0488 | 0.2287 | 0.4832 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0008 | 0.0008 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.003 | 0.003 |
Loa Loa (eye worm) | RNA binding protein | 0.0995 | 0.4733 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0104 | 0.086 |
Echinococcus multilocularis | tar DNA binding protein | 0.0995 | 0.4733 | 0.4733 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0008 | 0.031 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0121 | 0.0511 | 0.0511 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.017 | 0.0751 | 0.1587 |
Schistosoma mansoni | tar DNA-binding protein | 0.0995 | 0.4733 | 0.4733 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.003 | 0.003 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.003 | 0.0062 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0125 | 0.0533 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1358 | 0.2858 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Echinococcus granulosus | snurportin 1 | 0.0305 | 0.1399 | 0.1399 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0063 |
Echinococcus multilocularis | tumor protein p63 | 0.1357 | 0.6482 | 0.6482 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.004 | 0.0233 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0104 | 0.1878 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0142 | 0.0615 | 0.0615 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0144 | 0.0621 | 0.0621 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0144 | 0.0621 | 0.1312 |
Leishmania major | cysteine peptidase A (CPA) | 0.0017 | 0.0008 | 0.031 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0063 | 0.0234 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.003 | 0.0063 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0995 | 0.4733 | 1 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0066 | 0.0139 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0104 | 0.0952 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0104 | 0.0104 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0008 | 0.0008 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1358 | 0.2858 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0104 | 0.0202 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0088 | 0.0798 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.003 | 0.1215 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0104 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0063 |
Schistosoma mansoni | ferritin light chain | 0.0026 | 0.0055 | 0.0055 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1358 | 0.2858 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.0387 | 0.0387 |
Schistosoma mansoni | tar DNA-binding protein | 0.0995 | 0.4733 | 0.4733 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.003 | 0.003 |
Echinococcus granulosus | geminin | 0.0345 | 0.1592 | 0.1592 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.003 | 0.003 |
Brugia malayi | Bromodomain containing protein | 0.0074 | 0.0286 | 0.0605 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.003 | 0.0063 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0109 | 0.0213 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0104 | 0.4404 |
Schistosoma mansoni | Smad4 | 0.0033 | 0.0089 | 0.0089 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.003 | 0.0063 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0234 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.0387 | 0.0817 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0081 | 0.0319 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0454 | 0.2118 | 0.4476 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0155 | 0.0327 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0033 | 0.0089 | 0.0188 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0017 | 0.0008 | 0.0429 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0234 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0001 | 0.0001 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.003 | 0.003 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0104 | 0.022 |
Schistosoma mansoni | ferritin | 0.0026 | 0.0055 | 0.0055 |
Schistosoma mansoni | ferritin | 0.0026 | 0.0055 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0066 | 0.0139 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0104 | 0.0952 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.003 | 0.003 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0027 | 0.0057 |
Schistosoma mansoni | smad1 5 8 and | 0.0033 | 0.0089 | 0.0089 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.003 | 0.0063 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0008 | 0.0018 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0046 | 0.0046 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.0387 | 0.0387 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.003 | 0.003 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.003 | 0.003 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0024 | 0.0046 | 0.0046 |
Schistosoma mansoni | ran | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0621 | 0.0621 |
Echinococcus multilocularis | lamin dm0 | 0.017 | 0.0751 | 0.0751 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0156 | 0.0683 | 0.1443 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0047 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0104 | 0.022 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -1.06 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = -0.02 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 0 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 0.6 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 9 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 49 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 96 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition frequency index (IFI) (functional) | = 1.44 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
Percent growth inhibition (functional) | = -10 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 9 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 49 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 96 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
XC50 (functional) | = 6.1 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
XC50 (functional) | = 0.79975 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.