Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0046 | 0.0041 |
Echinococcus granulosus | flap endonuclease 1 | 0.003 | 0.0054 | 0.0045 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0162 | 0.0157 |
Loa Loa (eye worm) | Smad1 | 0.0027 | 0.0046 | 0.0041 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0034 | 0.5474 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.002 | 0.0015 |
Trypanosoma brucei | unspecified product | 0.002 | 0.002 | 0.0054 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.115 | 0.3796 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0133 | 0.0127 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0162 | 0.0153 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0035 | 0.0071 | 0.0057 |
Schistosoma mansoni | apoferritin-2 | 0.0063 | 0.0164 | 0.0154 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.0731 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0067 | 0.0179 | 0.017 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0009 | 0.0004 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0009 | 0.0004 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.002 | 0.2455 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0143 | 0.0431 | 0.1115 |
Schistosoma mansoni | flap endonuclease-1 | 0.0027 | 0.0045 | 0.0036 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0245 | 0.0774 | 0.0765 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0016 | 0.0009 | 0.0004 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0038 | 0.0081 | 0.0072 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0053 | 0.0114 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0046 | 0.0037 |
Giardia lamblia | Flap structure-specific endonuclease | 0.003 | 0.0054 | 0.6752 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0162 | 0.0405 |
Echinococcus multilocularis | musashi | 0.0173 | 0.0533 | 0.0524 |
Brugia malayi | Bromodomain containing protein | 0.0166 | 0.051 | 0.0505 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0009 | 0.0004 |
Loa Loa (eye worm) | glutathione reductase | 0.01 | 0.029 | 0.0285 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0229 | 0.0719 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0076 | 0.0071 |
Toxoplasma gondii | ABC1 family protein | 0.0074 | 0.0201 | 0.0507 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0302 | 0.0962 | 0.2516 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0076 | 0.0067 |
Loa Loa (eye worm) | thioredoxin reductase | 0.01 | 0.029 | 0.0285 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.002 | 0.0011 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.01 | 0.029 | 0.0279 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0302 | 0.0962 | 0.2516 |
Echinococcus granulosus | dihydrofolate reductase | 0.3008 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0021 | 0.0011 |
Echinococcus multilocularis | tumor protein p63 | 0.284 | 0.9439 | 0.9438 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0011 | 0.0002 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.115 | 0.3796 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0034 | 0.0068 | 0.0059 |
Plasmodium vivax | flap endonuclease 1, putative | 0.003 | 0.0054 | 0.0119 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0021 | 0.0015 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.115 | 0.3796 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0021 | 0.0011 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.115 | 0.3796 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0021 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 0.0533 | 0.0528 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0074 | 0.0201 | 0.0191 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0021 | 0.0015 |
Echinococcus multilocularis | zinc finger protein | 0.0043 | 0.01 | 0.009 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0026 | 0.004 | 0.0035 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0029 |
Schistosoma mansoni | hypothetical protein | 0.0245 | 0.0774 | 0.0765 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0021 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0034 | 0.0029 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.0637 | 0.0632 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.0201 | 0.0191 |
Onchocerca volvulus | 0.0024 | 0.0034 | 0.0186 | |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0021 | 0.0015 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0011 | 0.0006 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.3008 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0011 | 0.0002 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.0201 | 0.0196 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0035 | 0.0071 | 0.0163 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0074 | 0.0201 | 0.0187 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0054 |
Toxoplasma gondii | thioredoxin reductase | 0.01 | 0.029 | 0.0741 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.002 | 0.0029 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0021 | 0.0011 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0021 | 0.0011 |
Schistosoma mansoni | apoferritin-2 | 0.0063 | 0.0164 | 0.0154 |
Onchocerca volvulus | 0.0074 | 0.0201 | 0.1439 | |
Onchocerca volvulus | 0.0416 | 0.1343 | 1 | |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0021 | 0.0015 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0302 | 0.0962 | 0.2534 |
Onchocerca volvulus | 0.0173 | 0.0533 | 0.3927 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0021 | 0.0011 |
Toxoplasma gondii | hypothetical protein | 0.0049 | 0.0117 | 0.0285 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0027 | 0.0046 | 0.0041 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0034 | 0.0029 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0245 | 0.0774 | 0.0765 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0472 | 0.1529 | 0.152 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0071 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0021 | 0.0015 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0035 | 0.0071 | 0.0062 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0021 | 0.0015 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0029 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0021 | 0.0011 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0038 | 0.0081 | 0.0072 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0034 | 0.5474 |
Mycobacterium ulcerans | lipase LipD | 0.0074 | 0.0201 | 0.0187 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0053 | 0.0043 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0035 | 0.0071 | 0.0163 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0162 | 0.0405 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.002 | 0.0154 |
Echinococcus granulosus | tumor protein p63 | 0.284 | 0.9439 | 0.9438 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0071 | 0.0163 |
Schistosoma mansoni | bromodomain containing protein | 0.014 | 0.0423 | 0.0414 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0021 | 0.0015 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.002 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0234 | 0.0229 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0021 | 0.0015 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.01 | 0.029 | 0.0741 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0035 | 0.0071 | 0.0163 |
Brugia malayi | Thioredoxin reductase | 0.01 | 0.029 | 0.0285 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0014 | 0.0012 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0162 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0034 | 0.0029 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0034 | 0.002 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.3008 | 1 | 1 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.3008 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0035 | 0.0071 | 0.0163 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.002 | 0.0054 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.002 | 0.0011 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0687 | 0.2248 | 0.224 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0021 | 0.0015 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.0201 | 0.266 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0063 | 0.0164 | 0.013 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0034 | 0.002 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0038 | 0.0081 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0478 | 0.0473 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0201 | 0.0196 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0026 | 0.004 | 0.0035 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0021 | 0.0015 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0201 | 0.0507 |
Schistosoma mansoni | ferritin | 0.0063 | 0.0164 | 0.0154 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0021 | 0.0011 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0027 | 0.0046 | 0.0041 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0162 | 0.0157 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.0201 | 0.266 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0302 | 0.0962 | 0.2516 |
Echinococcus granulosus | smad | 0.0027 | 0.0046 | 0.0037 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0021 | 0.0011 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.003 | 0.0054 | 0.0144 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0011 | 0.0002 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0046 | 0.0041 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0014 | 0.0012 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0201 | 0.0507 |
Brugia malayi | Smad1 | 0.0027 | 0.0046 | 0.0041 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0021 | 0.0015 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0067 | 0.0179 | 0.017 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0035 | 0.0071 | 0.0163 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.0201 | 0.0191 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.002 | 0.0006 |
Loa Loa (eye worm) | ctsf protein | 0.0016 | 0.0009 | 0.0004 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0029 |
Schistosoma mansoni | smad | 0.0027 | 0.0046 | 0.0037 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0034 | 0.0065 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0254 | 0.0805 | 0.0795 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0021 | 0.0011 |
Onchocerca volvulus | 0.0232 | 0.0731 | 0.5411 | |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0035 | 0.0071 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0014 | 0.0009 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0021 | 0.0015 |
Brugia malayi | Bromodomain containing protein | 0.0085 | 0.0238 | 0.0233 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0021 | 0.0015 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0143 | 0.0431 | 0.1137 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0053 | 0.0043 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.002 | 0.0011 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0063 | 0.0164 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.002 | 0.0011 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0132 | 0.0396 | 0.0388 |
Echinococcus multilocularis | smad | 0.0027 | 0.0046 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0201 | 0.0196 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0057 | 0.0144 | 0.0357 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0229 | 0.0719 | 0.0688 |
Brugia malayi | Dihydrofolate reductase | 0.3008 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0162 | 0.0405 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0021 | 0.0011 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0021 | 0.0011 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0027 | 0.0046 | 0.0037 |
Echinococcus granulosus | expressed protein | 0.0063 | 0.0164 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0223 | 0.0218 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.002 | 0.0011 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0021 | 0.0011 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0021 | 0.0011 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.0068 | 0.0155 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0021 | 0.0084 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0021 | 0.0015 |
Plasmodium vivax | thioredoxin reductase, putative | 0.01 | 0.029 | 0.0741 |
Schistosoma mansoni | intermediate filament proteins | 0.0173 | 0.0533 | 0.0524 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.0201 | 0.0187 |
Plasmodium falciparum | thioredoxin reductase | 0.01 | 0.029 | 0.0741 |
Trypanosoma brucei | trypanothione reductase | 0.01 | 0.029 | 0.0764 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0071 | 0.0163 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.003 | 0.0054 | 0.0119 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0084 | 0.0234 | 0.0225 |
Echinococcus multilocularis | flap endonuclease 1 | 0.003 | 0.0054 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0239 | 0.0233 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0021 | 0.0011 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0009 | 0.0004 |
Mycobacterium ulcerans | beta-lactamase | 0.0074 | 0.0201 | 0.0187 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0071 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0021 | 0.0015 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.002 | 0.001 |
Plasmodium vivax | glutathione reductase, putative | 0.01 | 0.029 | 0.0741 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.115 | 0.3796 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0035 | 0.0071 | 0.0187 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0011 | 0.0006 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0021 | 0.0011 |
Schistosoma mansoni | ferritin light chain | 0.0063 | 0.0164 | 0.0154 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0071 | 0.0163 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0034 | 0.002 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0687 | 0.2248 | 0.224 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0035 | 0.0071 | 0.0057 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0074 | 0.0201 | 0.0196 |
Plasmodium falciparum | thioredoxin reductase | 0.0035 | 0.0071 | 0.0163 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0049 | 0.0118 | 0.0287 |
Trypanosoma cruzi | ISWI complex protein | 0.0034 | 0.0068 | 0.0155 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0229 | 0.0719 | 0.0709 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.002 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0021 | 0.0015 |
Brugia malayi | glutathione reductase | 0.01 | 0.029 | 0.0285 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0034 | 0.002 |
Plasmodium falciparum | glutathione reductase | 0.0035 | 0.0071 | 0.0163 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0201 | 0.266 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0034 | 0.5474 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0021 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0223 | 0.0218 |
Schistosoma mansoni | ferritin | 0.0063 | 0.0164 | 0.0154 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0201 | 0.266 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0021 | 0.0015 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0068 | 0.0059 |
Schistosoma mansoni | lamin | 0.0173 | 0.0533 | 0.0524 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0035 | 0.0071 | 0.0062 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0063 | 0.0164 | 0.0153 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0014 | 0.0003 |
Chlamydia trachomatis | dihydrofolate reductase | 0.3008 | 1 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0074 | 0.0201 | 0.0196 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0054 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0046 | 0.0041 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0201 | 0.0507 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0162 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0021 | 0.0015 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0254 | 0.0805 | 0.0795 |
Trypanosoma cruzi | ISWI complex protein | 0.0034 | 0.0068 | 0.0155 |
Entamoeba histolytica | Flap nuclease, putative | 0.003 | 0.0054 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0162 | 0.0153 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0054 |
Mycobacterium tuberculosis | Probable reductase | 0.0229 | 0.0719 | 0.0709 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.002 | 0.0006 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0162 | 0.0405 |
Schistosoma mansoni | ferritin light chain | 0.0063 | 0.0164 | 0.0154 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0096 | 0.023 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0035 | 0.0071 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0014 | 0.0009 |
Echinococcus granulosus | zinc finger protein | 0.0043 | 0.01 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0179 | 0.0174 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0021 | 0.0011 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.01 | 0.029 | 0.0281 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0074 | 0.0201 | 0.0192 |
Onchocerca volvulus | 0.0074 | 0.0201 | 0.1439 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0054 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0402 | 0.1296 | 0.1291 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0034 | 0.0029 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0021 | 0.0015 |
Schistosoma mansoni | ferritin | 0.0063 | 0.0164 | 0.0154 |
Brugia malayi | beta-lactamase | 0.0074 | 0.0201 | 0.0196 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0021 | 0.0015 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0096 | 0.0254 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Mycobacterium ulcerans | hypothetical protein | 0.0159 | 0.0485 | 0.0472 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0021 | 0.0015 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0132 | 0.0396 | 0.0388 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0687 | 0.2248 | 0.224 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0063 | 0.0164 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0173 | 0.0533 | 0.0524 |
Echinococcus granulosus | intermediate filament protein | 0.0173 | 0.0533 | 0.0524 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0054 |
Schistosoma mansoni | thyroid hormone receptor | 0.0265 | 0.084 | 0.0831 |
Plasmodium vivax | hypothetical protein, conserved | 0.0074 | 0.0201 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0201 | 0.0196 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0201 | 0.0196 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.002 | 0.0015 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0035 | 0.0071 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0201 | 0.0196 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0107 | 0.0098 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0067 | 0.0179 | 0.017 |
Echinococcus granulosus | lamin | 0.0173 | 0.0533 | 0.0524 |
Echinococcus multilocularis | Smad4 | 0.0027 | 0.0046 | 0.0037 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0011 | 0.0002 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.002 | 0.0029 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0035 | 0.0071 | 0.0163 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0173 | 0.0533 | 0.0528 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0021 | 0.0015 |
Trypanosoma brucei | ISWI complex protein | 0.0034 | 0.0068 | 0.0179 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0254 | 0.0805 | 0.0795 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0035 | 0.0071 | 0.0187 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0011 | 0.0002 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0054 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0035 | 0.0071 | 0.0163 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.002 | 0.0015 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0021 | 0.0011 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0162 | 0.0153 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0021 | 0.0015 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0021 | 0.0011 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0021 | 0.0015 |
Onchocerca volvulus | 0.002 | 0.0021 | 0.0084 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.0162 | 0.0405 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0162 | 0.0157 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0053 | 0.0047 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0133 | 0.0127 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0162 | 0.0153 |
Schistosoma mansoni | Smad4 | 0.0027 | 0.0046 | 0.0037 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0046 | 0.0037 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0063 | 0.0164 | 0.015 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0021 | 0.0084 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0162 | 0.0405 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0021 | 0.0011 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0035 | 0.0071 | 0.0057 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.0201 | 0.0191 |
Mycobacterium leprae | Probable lipase LipE | 0.0074 | 0.0201 | 0.0168 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0071 | 0.0163 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0074 | 0.0201 | 0.0191 |
Echinococcus multilocularis | lamin | 0.0173 | 0.0533 | 0.0524 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.0201 | 0.0192 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0035 | 0.0071 | 0.0187 |
Onchocerca volvulus | 0.0074 | 0.0201 | 0.1439 | |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0035 | 0.0071 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0416 | 0.1343 | 0.1338 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0034 | 0.0065 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0046 | 0.0041 |
Brugia malayi | intermediate filament protein | 0.0173 | 0.0533 | 0.0528 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0009 | 0.0004 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0035 | 0.0071 | 0.0062 |
Brugia malayi | PHD-finger family protein | 0.0055 | 0.0139 | 0.0134 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.003 | 0.0054 | 0.0049 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0038 | 0.0081 | 0.0072 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0159 | 0.0485 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0021 | 0.0015 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0071 | 0.0163 |
Echinococcus multilocularis | expressed protein | 0.0063 | 0.0164 | 0.0154 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0067 | 0.0179 | 0.017 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0009 | 0.0004 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0034 | 0.002 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0034 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0034 | 0.0029 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0021 | 0.0011 |
Schistosoma mansoni | zinc finger protein | 0.0043 | 0.01 | 0.009 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.002 | 0.0029 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.3008 | 1 | 1 |
Echinococcus multilocularis | dihydrofolate reductase | 0.3008 | 1 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0011 | 0.0002 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0162 | 0.0157 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0021 | 0.0011 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0074 | 0.0201 | 0.0191 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0074 | 0.0201 | 0.053 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0035 | 0.0071 | 0.0187 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0034 | 0.0023 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0021 | 0.0011 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0035 | 0.0071 | 0.0163 |
Leishmania major | trypanothione reductase | 0.01 | 0.029 | 0.0741 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.002 | 0.0054 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0027 | 0.0046 | 0.0037 |
Loa Loa (eye worm) | fibroinase | 0.0016 | 0.0009 | 0.0004 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0416 | 0.1343 | 0.1335 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.002 | 0.0011 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0053 | 0.0114 |
Trichomonas vaginalis | esterase, putative | 0.0074 | 0.0201 | 0.266 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0034 | 0.002 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.005 | 0.0122 | 0.0112 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0021 | 0.0011 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0039 | 0.0085 | 0.008 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0201 | 0.266 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0265 | 0.084 | 0.0831 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0046 | 0.0107 | 0.0102 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.002 | 0.001 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0229 | 0.0719 | 0.0709 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0035 | 0.0071 | 0.0163 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0063 | 0.0164 | 0.0153 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0021 | 0.0015 |
Loa Loa (eye worm) | cysteine protease | 0.0016 | 0.0009 | 0.0004 |
Schistosoma mansoni | lamin | 0.0173 | 0.0533 | 0.0524 |
Plasmodium falciparum | glutathione reductase | 0.01 | 0.029 | 0.0741 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0074 | 0.0201 | 0.0192 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Mycobacterium leprae | conserved hypothetical protein | 0.0074 | 0.0201 | 0.0168 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0074 | 0.0201 | 0.0191 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0021 | 0.0084 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0009 | 0.0004 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.002 | 0.0154 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.003 | 0.0054 | 0.0119 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0076 | 0.0071 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.115 | 0.3796 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.002 | 0.0015 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0162 | 0.0153 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0021 | 0.0015 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0402 | 0.1296 | 0.1291 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0093 | 0.0265 | 0.0259 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0162 | 0.0405 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0096 | 0.023 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0034 | 0.002 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.0637 | 0.0632 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0021 | 0.0011 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0173 | 0.0533 | 0.0528 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0229 | 0.0719 | 0.0709 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0084 | 0.0234 | 0.0225 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.003 | 0.0054 | 0.0119 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0021 | 0.0015 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.002 | 0.0054 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0046 | 0.0037 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0074 | 0.0201 | 0.0191 |
Brugia malayi | MH2 domain containing protein | 0.0402 | 0.1296 | 0.1291 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.003 | 0.0054 | 0.0626 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0071 | 0.0163 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0034 | 0.0065 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.005 | 0.0122 | 0.0112 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0021 | 0.0011 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.008 | 0.0221 | 0.0212 |
Loa Loa (eye worm) | intermediate filament protein | 0.0173 | 0.0533 | 0.0528 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0093 | 0.0265 | 0.0259 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0021 | 0.0015 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0011 | 0.0002 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0096 | 0.023 |
Trichomonas vaginalis | ferritin, putative | 0.0063 | 0.0164 | 0.2139 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0011 | 0.0002 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0162 | 0.0157 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0035 | 0.0071 | 0.0066 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0011 | 0.0002 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0034 | 0.002 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0011 | 0.0006 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0027 | 0.0046 | 0.0037 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0027 | 0.0046 | 0.0037 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0054 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.005 | 0.0122 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.027 | 0.0265 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0035 | 0.0071 | 0.0854 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0074 | 0.0201 | 0.0191 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0027 | 0.0046 | 0.0037 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0021 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0014 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0009 | 0.0004 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0063 | 0.0164 | 0.015 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0011 | 0.0006 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0021 | 0.0015 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0016 | 0.0009 | 0.0004 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0074 | 0.0201 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0133 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0014 | 0.0009 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.008 | 0.0221 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0201 | 0.0196 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0254 | 0.0805 | 0.0773 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0014 | 0.0009 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0229 | 0.0719 | 0.0709 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0035 | 0.0071 | 0.0854 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.0201 | 0.0196 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.002 | 0.0011 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0021 | 0.0011 |
Schistosoma mansoni | dihydrofolate reductase | 0.3008 | 1 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0143 | 0.0431 | 0.1115 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.0201 | 0.0192 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Echinococcus granulosus | ferritin | 0.0063 | 0.0164 | 0.0154 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0021 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.0522 | 0.0517 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0021 | 0.0015 |
Onchocerca volvulus | 0.0173 | 0.0533 | 0.3927 | |
Echinococcus granulosus | lamin dm0 | 0.0173 | 0.0533 | 0.0524 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0021 | 0.0015 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0053 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0256 | 0.0251 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0049 | 0.004 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0035 | 0.0071 | 0.0057 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0133 | 0.0127 |
Echinococcus granulosus | Smad4 | 0.0027 | 0.0046 | 0.0037 |
Plasmodium falciparum | flap endonuclease 1 | 0.003 | 0.0054 | 0.0119 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.01 | 0.029 | 0.0281 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0074 | 0.0201 | 0.0196 |
Schistosoma mansoni | thyroid hormone receptor | 0.0265 | 0.084 | 0.0831 |
Onchocerca volvulus | 0.0029 | 0.0053 | 0.0325 | |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.002 | 0.0054 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.002 | 0.0029 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0011 | 0.0002 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0034 | 0.0023 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0074 | 0.0201 | 0.0191 |
Schistosoma mansoni | ferritin | 0.0063 | 0.0164 | 0.0154 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0052 | 0.0127 | 0.0312 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0021 | 0.0015 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Echinococcus multilocularis | ferritin | 0.0063 | 0.0164 | 0.0154 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0162 | 0.0428 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0162 | 0.0157 |
Brugia malayi | Flap endonuclease-1 | 0.003 | 0.0054 | 0.0049 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 1 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 4 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 93 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 97 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition frequency index (IFI) (functional) | = 19.85 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 1 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 4 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 93 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 97 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
XC50 (functional) | = 6.1 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
XC50 (functional) | = 0.8026 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.