Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0127 | 1 | 1 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0127 | 1 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0127 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0127 | 1 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0049 | 0.2848 | 0.2848 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0127 | 1 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Echinococcus granulosus | g protein coupled receptor | 0.0127 | 1 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0049 | 0.2848 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0127 | 1 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0127 | 1 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0 | 0.5 |
Brugia malayi | GnHR receptor homolog | 0.0127 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0127 | 1 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0049 | 0.2848 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0127 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.2848 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0127 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.2848 | 1 |
Brugia malayi | hypothetical protein | 0.0127 | 1 | 1 |
Brugia malayi | Serotonin receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0127 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0127 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.2848 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | orexin receptor type 2 | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0127 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.2848 | 1 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | somatostatin receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.3945 | 0.3945 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0.2848 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.3945 | 0.3945 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0049 | 0.2848 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Echinococcus multilocularis | fmrfamide receptor | 0.0127 | 1 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus granulosus | serotonin receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0127 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.2848 | 0.2848 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0 | 0.5 |
Brugia malayi | Dopamine receptor protein 2 | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0049 | 0.2848 | 0.2848 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0127 | 1 | 1 |
Echinococcus multilocularis | allatostatin A receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0127 | 1 | 1 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0127 | 1 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0127 | 1 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0127 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0127 | 1 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0127 | 1 | 1 |
Brugia malayi | Dopamine receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0127 | 1 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0127 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0127 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.3945 | 0.3945 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0127 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.3945 | 0.3945 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.3945 | 0.3945 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0127 | 1 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0127 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0049 | 0.2848 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0127 | 1 | 1 |
Echinococcus multilocularis | sex peptide receptor | 0.0127 | 1 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0127 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0127 | 1 | 1 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.3945 | 0.3945 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0127 | 1 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0127 | 1 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Brugia malayi | G-protein coupled receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0127 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0049 | 0.2848 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0127 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0 | 0.5 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0127 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0061 | 0.3945 | 0.3945 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0049 | 0.2848 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0127 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0049 | 0.2848 | 0.2848 |
Brugia malayi | Dopamine receptor protein 1 | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0127 | 1 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0127 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Echinococcus granulosus | allatostatin A receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Brugia malayi | larval opioid receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Echinococcus granulosus | fmrfamide receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.3945 | 0.3945 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0127 | 1 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0127 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0127 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0127 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0127 | 1 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.0127 | 1 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0 | 0.5 |
Brugia malayi | Melatonin receptor type 1A | 0.0127 | 1 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0127 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0127 | 1 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0127 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0127 | 1 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0127 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0127 | 1 | 1 |
Brugia malayi | RE15519p | 0.0127 | 1 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0127 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.3945 | 0.3945 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0127 | 1 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0049 | 0.2848 | 0.2848 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0049 | 0.2848 | 0.2848 |
Schistosoma mansoni | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0127 | 1 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0049 | 0.2848 | 1 |
Schistosoma mansoni | amine GPCR | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0127 | 1 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Brugia malayi | AKH receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0127 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0127 | 1 | 1 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0127 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0127 | 1 | 1 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0127 | 1 | 0.5 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.3945 | 0.3945 |
Echinococcus granulosus | somatostatin receptor | 0.0127 | 1 | 1 |
Brugia malayi | G protein-coupled receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0127 | 1 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0127 | 1 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0127 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0127 | 1 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0049 | 0.2848 | 1 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.3945 | 0.3945 |
Schistosoma mansoni | myosin xvIII | 0.0127 | 1 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0127 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0127 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.3945 | 0.3945 |
Onchocerca volvulus | 0.0127 | 1 | 0.5 | |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0127 | 1 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0127 | 1 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0127 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0127 | 1 | 1 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0127 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0127 | 1 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0127 | 1 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0127 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0.2848 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0049 | 0.2848 | 0.2848 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0127 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.3945 | 0.3945 |
Schistosoma mansoni | neuropeptide receptor | 0.0127 | 1 | 1 |
Brugia malayi | Serotonin receptor | 0.0127 | 1 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0127 | 1 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0127 | 1 | 1 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0127 | 1 | 1 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0127 | 1 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0127 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0127 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 0 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 2.34 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 3.05 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 3.4 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 20 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 25 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 98 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition frequency index (IFI) (functional) | = 0.72 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
Percent growth inhibition (functional) | = -1 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 20 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 25 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 98 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
XC50 (functional) | = 6.8 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
XC50 (functional) | = 0.1574 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.