Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | neuropeptide Y receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0021 | 0.0148 | 0.5893 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | opsin-like receptor | 0.0022 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0022 | 0.0222 | 0.0198 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0024 | 0.043 | 0.0346 |
Echinococcus granulosus | allatostatin A receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0022 | 0.0222 | 0.0222 |
Onchocerca volvulus | 0.0021 | 0.0148 | 0.5893 | |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0024 | 0.043 | 0.0426 |
Schistosoma mansoni | biogenic amine receptor | 0.0022 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.9176 | 1 |
Schistosoma mansoni | amine GPCR | 0.0022 | 0.0222 | 0.0222 |
Onchocerca volvulus | 0.0021 | 0.0148 | 0.5893 | |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | acetylcholinesterase | 0.0021 | 0.0148 | 0.0148 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0022 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0148 | 0.0116 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0024 | 0.043 | 0.043 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Echinococcus multilocularis | serotonin receptor | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0021 | 0.0148 | 0.5893 | |
Brugia malayi | Carboxylesterase family protein | 0.0021 | 0.0148 | 0.0116 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0021 | 0.0148 | 0.0116 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0024 | 0.043 | 0.0426 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0042 | 0.0042 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0042 | 0.0042 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | carboxylesterase | 0.0021 | 0.0148 | 0.0116 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0148 | 0.0116 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Echinococcus multilocularis | orexin receptor type 2 | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | g protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | somatostatin receptor | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0021 | 0.0148 | 0.0116 |
Brugia malayi | Dopamine receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | GnHR receptor homolog | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0024 | 0.043 | 0.043 |
Echinococcus granulosus | neuropeptide receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus granulosus | orexin receptor type 2 | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | neuropeptide receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0024 | 0.043 | 0.0426 |
Echinococcus multilocularis | acetylcholinesterase | 0.0126 | 0.9176 | 1 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Echinococcus granulosus | neuropeptides capa receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | amine GPCR | 0.0022 | 0.0222 | 0.0222 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0124 | 0.9017 | 0.9825 |
Loa Loa (eye worm) | carboxylesterase | 0.0021 | 0.0148 | 0.0116 |
Brugia malayi | neuropeptide F receptor | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0124 | 0.9017 | 0.9825 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0042 | 0.0042 |
Echinococcus granulosus | neuropeptide receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0124 | 0.9017 | 0.9825 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | acetylcholinesterase | 0.0126 | 0.9176 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0022 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | carboxylesterase | 0.0126 | 0.9176 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1414 | 0.1502 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.9176 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0126 | 0.9176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | AKH receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0021 | 0.0148 | 0.0116 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0126 | 0.9176 | 1 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0024 | 0.043 | 0.0426 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0024 | 0.043 | 0.0346 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0021 | 0.0148 | 0.5 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0021 | 0.0148 | 0.0148 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0024 | 0.043 | 0.0426 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0126 | 0.9176 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0022 | 0.0222 | 0.0222 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0021 | 0.0148 | 0.0148 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0021 | 0.0148 | 0.0148 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0148 | 0.0116 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0222 | 0.0222 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | voltage gated potassium channel | 0.0036 | 0.1414 | 0.1502 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | g protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0024 | 0.043 | 0.0426 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0022 | 0.0222 | 0.0222 |
Brugia malayi | Carboxylesterase family protein | 0.0021 | 0.0148 | 0.0116 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0022 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0021 | 0.0148 | 0.0148 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0024 | 0.043 | 0.0426 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | g protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus granulosus | acetylcholinesterase | 0.0126 | 0.9176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | sulfakinin receptor protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | sex peptide receptor | 0.0022 | 0.0222 | 0.0198 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0116 | 0.8312 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Schistosoma mansoni | gliotactin | 0.0021 | 0.0148 | 0.0148 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0021 | 0.0148 | 0.0116 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0126 | 0.9176 | 0.9176 |
Echinococcus granulosus | acetylcholinesterase | 0.0126 | 0.9176 | 1 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | myosin xvIII | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0042 | 0.0042 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0022 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | RE15519p | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Echinococcus multilocularis | voltage gated potassium channel | 0.0036 | 0.1414 | 0.1502 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0024 | 0.043 | 0.043 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0022 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | G-protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0042 | 0.0042 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0021 | 0.0148 | 0.0116 |
Brugia malayi | Carboxylesterase family protein | 0.0021 | 0.0148 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.7603 | 0.8278 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0024 | 0.043 | 0.0426 |
Echinococcus granulosus | sex peptide receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0148 | 0.0116 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.0021 | 0.0148 | 0.0116 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0036 | 0.1414 | 0.1414 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0024 | 0.043 | 0.0426 |
Echinococcus granulosus | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0042 | 0.0042 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0222 | 0.0222 |
Brugia malayi | Carboxylesterase family protein | 0.0021 | 0.0148 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0148 | 0.0116 |
Schistosoma mansoni | biogenic amine receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | serotonin receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0024 | 0.043 | 0.0426 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0024 | 0.043 | 0.043 |
Brugia malayi | putative neuropeptide receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0148 | 0.0116 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0036 | 0.1414 | 0.1502 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | adenoreceptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.043 | 0.0426 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0148 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0022 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0036 | 0.1414 | 0.1502 |
Brugia malayi | G-protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0042 | 0.0042 |
Schistosoma mansoni | neuropeptide receptor | 0.0022 | 0.0222 | 0.0222 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0124 | 0.9017 | 0.9825 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0022 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | opsin-like receptor | 0.0022 | 0.0222 | 0.0222 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | amine GPCR | 0.0022 | 0.0222 | 0.0222 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0024 | 0.043 | 0.0426 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0022 | 0.0222 | 0.0222 |
Onchocerca volvulus | 0.0021 | 0.0148 | 0.5893 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0022 | 0.0222 | 0.0222 |
Brugia malayi | Dopamine receptor protein 2 | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | opsin-like receptor | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0022 | 0.0222 | 0.0222 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0042 | 0.0042 |
Echinococcus multilocularis | allatostatin A receptor | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | Serotonin receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | follicle stimulating hormone receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | G protein-coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0021 | 0.0148 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0135 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Schistosoma mansoni | neuropeptide receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus multilocularis | fmrfamide receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0024 | 0.043 | 0.0426 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0024 | 0.043 | 0.0426 |
Brugia malayi | Melatonin receptor type 1A | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0022 | 0.0222 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | neuropeptide F receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | serotonin receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | neuropeptide receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0024 | 0.043 | 0.0426 |
Echinococcus granulosus | g-protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | fmrfamide receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0024 | 0.043 | 0.043 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0148 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0024 | 0.043 | 0.043 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | fmrfamide receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0022 | 0.0222 | 0.0198 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0116 | 0.8312 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0022 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0042 | 0.0042 |
Echinococcus multilocularis | neuropeptide receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | ORL1-like opioid receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0036 | 0.1414 | 0.1502 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0021 | 0.0148 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0042 | 0.0042 |
Echinococcus multilocularis | somatostatin receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus granulosus | neuropeptide s receptor | 0.0022 | 0.0222 | 0.0198 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0021 | 0.0148 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Brugia malayi | larval opioid receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0042 | 0.0042 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | amine GPCR | 0.0022 | 0.0222 | 0.0222 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.0126 | 0.9176 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0126 | 0.9176 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0042 | 0.0042 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0022 | 0.0222 | 0.0222 |
Echinococcus multilocularis | g protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0021 | 0.0148 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0021 | 0.0148 | 0.0116 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0022 | 0.0222 | 0.0222 |
Brugia malayi | Serotonin receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0022 | 0.0222 | 0.0222 |
Schistosoma mansoni | neuropeptide receptor | 0.0022 | 0.0222 | 0.0222 |
Echinococcus granulosus | g protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0036 | 0.1414 | 0.1414 |
Echinococcus multilocularis | neuroligin | 0.0021 | 0.0148 | 0.0116 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0022 | 0.0222 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | 0.0022 | 0.0222 | 1 | |
Brugia malayi | hypothetical protein | 0.0022 | 0.0222 | 0.0198 |
Schistosoma mansoni | amine GPCR | 0.0022 | 0.0222 | 0.0222 |
Echinococcus granulosus | g protein coupled receptor | 0.0022 | 0.0222 | 0.0198 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0022 | 0.0222 | 0.0198 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0022 | 0.0222 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 100 uM | In vitro growth inhibitory activity against Trypanosoma brucei strain LAB110 | ChEMBL. | 11412992 |
IC50 (functional) | > 100 uM | In vitro growth inhibitory activity against Trypanosoma brucei strain K243 | ChEMBL. | 11412992 |
IC50 (functional) | > 100 uM | In vitro growth inhibitory activity against Trypanosoma brucei strain LAB110 | ChEMBL. | 11412992 |
IC50 (functional) | > 100 uM | In vitro growth inhibitory activity against Trypanosoma brucei strain K243 | ChEMBL. | 11412992 |
IC50 (functional) | = 232 uM | In vitro growth inhibitory activity against E. cuniculi grown on RK-13 cells infected as a monolayer | ChEMBL. | 11412992 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.