Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0093 | 0.0373 | 0.0712 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.0116 | 0.0222 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0163 | 0.0699 | 0.1335 |
Schistosoma mansoni | intermediate filament proteins | 0.0169 | 0.0729 | 0.0729 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0163 | 0.0699 | 0.0699 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0007 | 0.0302 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Schistosoma mansoni | ferritin light chain | 0.0043 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0056 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0021 | 0.0021 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0018 | 0.0019 | 0.0019 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.0233 | 1 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0036 | 0.0101 | 0.0912 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0018 | 0.0019 | 0.0035 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1692 | 0.7921 | 0.7921 |
Schistosoma mansoni | bromodomain containing protein | 0.0061 | 0.0221 | 0.0221 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.003 | 0.0056 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0161 | 0.0691 | 0.0691 |
Mycobacterium leprae | Probable lipase LipE | 0.0039 | 0.0116 | 0.1754 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0164 | 0.0313 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.003 | 0.003 |
Echinococcus granulosus | tar DNA binding protein | 0.1124 | 0.5237 | 0.5237 |
Echinococcus granulosus | lamin dm0 | 0.0169 | 0.0729 | 0.0729 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0049 | 0.0164 | 0.1147 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.1429 | 0.3075 |
Brugia malayi | RNA recognition motif domain containing protein | 0.1124 | 0.5237 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0049 | 0.0164 | 0.2471 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Echinococcus granulosus | lamin | 0.0169 | 0.0729 | 0.0729 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.003 | 0.0056 |
Brugia malayi | TAR-binding protein | 0.1124 | 0.5237 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0035 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0782 | 0.3626 | 0.3626 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.003 | 0.0056 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.003 | 0.0064 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | survival motor neuron protein | 0.016 | 0.0685 | 0.0685 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0102 | 0.4379 |
Brugia malayi | MH1 domain containing protein | 0.0041 | 0.0126 | 0.024 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0116 | 0.025 |
Onchocerca volvulus | 0.0126 | 0.0526 | 0.1132 | |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0142 | 0.0604 | 0.0604 |
Loa Loa (eye worm) | hypothetical protein | 0.0508 | 0.2331 | 0.4451 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.003 | 0.0064 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0029 | 0.0548 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0011 | 0.0011 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0041 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0105 | 0.0201 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0102 | 0.022 |
Brugia malayi | MH1 domain containing protein | 0.0041 | 0.0126 | 0.024 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0132 | 0.0556 | 0.0556 |
Schistosoma mansoni | microtubule-associated protein tau | 0.2132 | 1 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0049 | 0.0164 | 0.2471 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.003 | 0.003 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0082 | 0.0317 | 0.0317 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0116 | 0.0222 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0121 | 0.0261 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0037 | 0.0105 | 0.2 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.0164 | 0.2471 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0039 | 0.0116 | 0.1048 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0029 | 0.0062 |
Echinococcus multilocularis | geminin | 0.0347 | 0.157 | 0.157 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0058 | 0.0207 | 0.8879 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Schistosoma mansoni | hypothetical protein | 0.0132 | 0.0556 | 0.0556 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0164 | 0.7028 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | nuclear factor I | 0.0023 | 0.0039 | 0.0075 |
Brugia malayi | MH2 domain containing protein | 0.0603 | 0.2778 | 0.5306 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.004 | 0.0121 | 0.1826 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0041 | 0.0126 | 0.024 |
Onchocerca volvulus | 0.0039 | 0.0116 | 0.025 | |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0024 | 0.0046 | 0.0046 |
Brugia malayi | MH1 domain containing protein | 0.0023 | 0.0039 | 0.0075 |
Schistosoma mansoni | lamin | 0.0169 | 0.0729 | 0.0729 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.0373 | 0.0373 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.003 | 0.0056 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0142 | 0.0604 | 0.0604 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0007 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0121 | 0.5192 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0317 | 0.1429 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0126 | 0.0526 | 1 |
Echinococcus multilocularis | expressed protein | 0.0043 | 0.0133 | 0.0133 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0029 | 0.1236 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0011 | 0.0208 |
Schistosoma mansoni | apoferritin-2 | 0.0043 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0782 | 0.3626 | 0.6924 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0036 | 0.0101 | 0.1527 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.0164 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.0729 | 0.1393 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0039 | 0.0075 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0007 |
Schistosoma mansoni | ferritin light chain | 0.0043 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.0011 | 0.0021 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0161 | 0.0691 | 0.0691 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0102 | 0.022 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.1429 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0302 | 0.0577 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0039 | 0.0116 | 0.1754 |
Schistosoma mansoni | ferritin | 0.0043 | 0.0133 | 0.0133 |
Schistosoma mansoni | tar DNA-binding protein | 0.1124 | 0.5237 | 0.5237 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0029 | 0.0055 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0039 | 0.0116 | 0.0116 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.0691 | 0.0691 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0029 | 0.0055 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.003 | 0.0056 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.0116 | 0.025 |
Schistosoma mansoni | apoferritin-2 | 0.0043 | 0.0133 | 0.0133 |
Echinococcus multilocularis | tar DNA binding protein | 0.1124 | 0.5237 | 0.5237 |
Onchocerca volvulus | 0.016 | 0.0685 | 0.1475 | |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0029 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0317 | 0.0605 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0021 | 0.0021 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0024 | 0.0046 | 0.0872 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0102 | 0.0195 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0169 | 0.0729 | 0.1393 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0011 | 0.0024 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0039 | 0.0116 | 0.1048 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0024 | 0.0046 | 0.0872 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.0715 | 0.1365 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0164 | 0.2471 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0078 | 0.0302 | 0.0302 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.0691 | 0.0691 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0161 | 0.0691 | 0.0691 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0116 | 0.1048 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0018 | 0.0019 | 0.0019 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0011 | 0.047 |
Schistosoma mansoni | ran | 0.0021 | 0.0029 | 0.0029 |
Schistosoma mansoni | smad | 0.0041 | 0.0126 | 0.0126 |
Echinococcus granulosus | expressed protein | 0.0043 | 0.0133 | 0.0133 |
Schistosoma mansoni | smad1 5 8 and | 0.0041 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0116 | 0.0222 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0161 | 0.0691 | 0.0691 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.003 | 0.0056 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.003 | 0.003 |
Echinococcus granulosus | GPCR family 2 | 0.0161 | 0.0691 | 0.0691 |
Toxoplasma gondii | ABC1 family protein | 0.0039 | 0.0116 | 0.221 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0046 | 0.0046 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.1429 | 0.3075 |
Echinococcus multilocularis | musashi | 0.0169 | 0.0729 | 0.0729 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0121 | 0.0121 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.0691 | 0.0691 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0011 | 0.047 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.003 | 0.003 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0121 | 0.5192 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0029 | 0.1236 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0105 | 0.0201 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0024 | 0.0046 | 0.0088 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0102 | 0.022 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0002 | 0.0002 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0121 | 0.0504 | 0.0504 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.003 | 0.003 |
Brugia malayi | hypothetical protein | 0.0078 | 0.0302 | 0.0577 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0096 | 0.0096 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0029 | 0.0548 |
Loa Loa (eye worm) | TAR-binding protein | 0.1124 | 0.5237 | 1 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0013 | 0.0024 |
Loa Loa (eye worm) | RNA binding protein | 0.1124 | 0.5237 | 1 |
Schistosoma mansoni | ferritin | 0.0043 | 0.0133 | 0.0133 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0041 | 0.0126 | 0.024 |
Brugia malayi | intermediate filament protein | 0.0169 | 0.0729 | 0.1393 |
Onchocerca volvulus | 0.0017 | 0.0011 | 0.0024 | |
Schistosoma mansoni | thyroid hormone receptor | 0.0153 | 0.0653 | 0.0653 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.003 | 0.0056 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0013 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.1124 | 0.5237 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.0233 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.0011 | 0.0021 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.003 | 0.0056 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.1429 | 0.3075 |
Loa Loa (eye worm) | inositol-1 | 0.004 | 0.0121 | 0.0231 |
Echinococcus multilocularis | GPCR, family 2 | 0.0161 | 0.0691 | 0.0691 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.003 | 0.003 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0096 | 0.0096 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0039 | 0.0116 | 0.0222 |
Schistosoma mansoni | smad1 5 8 and | 0.0041 | 0.0126 | 0.0126 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0102 | 0.022 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0011 | 0.0011 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0064 | 0.0064 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0011 | 0.0011 |
Mycobacterium ulcerans | lipase LipD | 0.0039 | 0.0116 | 0.1754 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.004 | 0.0121 | 0.0261 |
Schistosoma mansoni | Smad4 | 0.0018 | 0.0019 | 0.0019 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.003 | 0.003 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0037 | 0.0105 | 0.1587 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0127 | 0.0242 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0013 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0164 | 0.7028 |
Loa Loa (eye worm) | hypothetical protein | 0.0347 | 0.1572 | 0.3001 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0064 | 0.6042 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0096 | 0.0863 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0018 | 0.0019 | 0.0035 |
Echinococcus granulosus | geminin | 0.0347 | 0.157 | 0.157 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0118 | 0.0225 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0102 | 0.022 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0039 | 0.1659 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Brugia malayi | Pre-SET motif family protein | 0.0126 | 0.0526 | 0.1005 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0039 | 0.0116 | 0.1048 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.003 | 0.003 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0017 | 0.0011 | 0.0024 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0102 | 0.4379 |
Onchocerca volvulus | 0.0169 | 0.0729 | 0.1569 | |
Onchocerca volvulus | 0.0017 | 0.0011 | 0.0024 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0161 | 0.0691 | 0.1319 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0011 | 0.0077 |
Trichomonas vaginalis | ferritin, putative | 0.0043 | 0.0133 | 0.0287 |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.0011 | 0.0021 |
Loa Loa (eye worm) | intermediate filament protein | 0.0169 | 0.0729 | 0.1393 |
Echinococcus multilocularis | Smad4 | 0.0041 | 0.0126 | 0.0126 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0024 | 0.0046 | 0.4359 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0056 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.0164 | 0.2471 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0132 | 0.0556 | 0.0556 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0302 | 0.0577 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0011 | 0.047 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0116 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0056 |
Echinococcus granulosus | smad | 0.0041 | 0.0126 | 0.0126 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.003 | 0.003 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0096 | 0.0863 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0011 | 0.0011 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0035 | 0.0035 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0011 | 0.047 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.003 | 0.003 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0116 | 0.4987 |
Echinococcus granulosus | intermediate filament protein | 0.0169 | 0.0729 | 0.0729 |
Onchocerca volvulus | 0.0049 | 0.0164 | 0.0353 | |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0878 | 0.4076 | 0.7783 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0126 | 0.0526 | 0.0526 |
Onchocerca volvulus | 0.0017 | 0.0011 | 0.0024 | |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0043 | 0.0133 | 0.1201 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0161 | 0.0691 | 0.1319 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.003 | 0.003 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.2132 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.003 | 0.0056 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.003 | 0.0056 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.003 | 0.0056 |
Trichomonas vaginalis | chaperonin, putative | 0.0024 | 0.0046 | 0.0099 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0011 | 0.0011 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.003 | 0.003 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0007 | 0.0302 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0096 | 0.0863 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0163 | 0.0699 | 0.1335 |
Schistosoma mansoni | tar DNA-binding protein | 0.1124 | 0.5237 | 0.5237 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0046 | 0.1967 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0011 | 0.0011 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.1429 | 0.3075 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0046 | 0.1967 |
Echinococcus multilocularis | lamin | 0.0169 | 0.0729 | 0.0729 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.003 | 0.0056 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.0116 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.0691 | 0.1319 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.0592 | 0.0592 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0134 |
Schistosoma mansoni | ferritin | 0.0043 | 0.0133 | 0.0133 |
Plasmodium vivax | SET domain protein, putative | 0.0126 | 0.0526 | 1 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0043 | 0.0133 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0155 | 0.0663 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0011 | 0.0021 |
Echinococcus multilocularis | snurportin 1 | 0.0298 | 0.1338 | 0.1338 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0205 | 0.0205 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0011 | 0.047 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0093 | 0.0373 | 0.0712 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0116 | 0.1048 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0163 | 0.0699 | 0.0699 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0011 | 0.047 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.003 | 0.0056 |
Schistosoma mansoni | tar DNA-binding protein | 0.1124 | 0.5237 | 0.5237 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0029 | 0.0029 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0039 | 0.0083 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.001 | 0.001 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0169 | 0.0729 | 0.1393 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0024 | 0.0046 | 0.0046 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.0116 | 0.0222 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0049 | 0.0164 | 0.1476 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.003 | 0.0056 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0116 | 0.025 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0043 | 0.0133 | 0.1201 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.003 | 0.0064 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0102 | 0.0195 |
Onchocerca volvulus | 0.0039 | 0.0116 | 0.025 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0603 | 0.2778 | 0.5306 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.0373 | 0.0373 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0126 | 0.0526 | 0.0526 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0011 | 0.0021 |
Mycobacterium ulcerans | beta-lactamase | 0.0039 | 0.0116 | 0.1754 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0163 | 0.0699 | 0.0699 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0102 | 0.4379 |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.0116 | 0.1754 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0102 | 0.0715 |
Schistosoma mansoni | hypothetical protein | 0.0347 | 0.157 | 0.157 |
Onchocerca volvulus | 0.0094 | 0.0376 | 0.0808 | |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0508 | 0.2331 | 0.4451 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0604 | 0.1154 |
Schistosoma mansoni | Smad4 | 0.0041 | 0.0126 | 0.0126 |
Echinococcus multilocularis | lamin dm0 | 0.0169 | 0.0729 | 0.0729 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.005 | 0.0169 | 0.7234 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0024 | 0.0046 | 0.0122 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.0373 | 0.0373 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0029 | 0.1236 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.003 | 0.003 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.0233 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0164 | 0.7028 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0049 | 0.0164 | 0.1476 |
Echinococcus granulosus | Smad4 | 0.0041 | 0.0126 | 0.0126 |
Brugia malayi | RNA, U transporter 1 | 0.0079 | 0.0306 | 0.0585 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0049 | 0.0164 | 0.2471 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0037 | 0.0105 | 0.0948 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0007 | 0.0134 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0105 | 0.0201 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0049 | 0.0164 | 0.2471 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0603 | 0.2778 | 0.5306 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0041 | 0.0126 | 0.024 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.003 | 0.003 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0302 | 0.0302 |
Onchocerca volvulus | 0.0039 | 0.0116 | 0.025 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0056 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0002 | 0.0075 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.003 | 0.0056 |
Trichomonas vaginalis | esterase, putative | 0.0039 | 0.0116 | 0.025 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.0691 | 0.0691 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0142 | 0.0604 | 0.0604 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0107 | 0.0204 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0039 | 0.0116 | 0.1048 |
Echinococcus granulosus | ferritin | 0.0043 | 0.0133 | 0.0133 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0007 | 0.0302 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.003 | 0.003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.003 | 0.0056 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0164 | 0.2471 |
Onchocerca volvulus | 0.0999 | 0.4648 | 1 | |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.0011 | 0.0021 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0018 | 0.0019 | 0.0019 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.0373 | 0.0373 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Trichomonas vaginalis | set domain proteins, putative | 0.0999 | 0.4648 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0121 | 0.0261 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0024 | 0.0046 | 0.0099 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0018 | 0.0019 | 0.004 |
Onchocerca volvulus | 0.0021 | 0.003 | 0.0064 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0142 | 0.0604 | 0.0604 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.003 | 0.0056 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.0373 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0056 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0164 | 0.0313 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0017 | 0.0011 | 0.1042 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0116 | 0.0222 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0039 | 0.0116 | 0.0116 |
Onchocerca volvulus | 0.0169 | 0.0729 | 0.1569 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0011 | 0.0024 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.003 | 0.003 |
Leishmania major | cysteine peptidase A (CPA) | 0.0017 | 0.0011 | 0.047 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0039 | 0.0116 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0056 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.004 | 0.0121 | 0.2301 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0011 | 0.0021 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0102 | 0.0102 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.1429 | 0.3075 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0007 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0064 | 0.1209 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0039 | 0.0116 | 0.1048 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0096 | 0.0863 |
Onchocerca volvulus | 0.0017 | 0.0011 | 0.0024 | |
Onchocerca volvulus | 0.0017 | 0.0011 | 0.0024 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.0233 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.1124 | 0.5237 | 0.5237 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0247 | 0.1099 | 0.1099 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.003 | 0.0056 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | smad | 0.0018 | 0.0019 | 0.0019 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.004 | 0.0121 | 0.0847 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0102 | 0.0715 |
Brugia malayi | Pre-SET motif family protein | 0.0878 | 0.4076 | 0.7783 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0026 | 0.005 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0011 | 0.0077 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0039 | 0.1659 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0298 | 0.1338 | 0.2555 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0018 | 0.0019 | 0.0019 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0017 | 0.0011 | 0.1042 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.003 | 0.003 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0011 | 0.0011 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0011 | 0.0021 |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.0011 | 0.0021 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0039 | 0.0271 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.0233 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0164 | 0.0313 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0002 | 0.0075 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0078 | 0.0302 | 0.0302 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0046 | 0.0088 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0041 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.003 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0056 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.0233 | 1 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0039 | 0.0083 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0121 | 0.0121 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.0302 | 0.2114 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0011 | 0.0011 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0205 | 0.0205 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.003 | 0.0056 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.004 | 0.0121 | 0.0121 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0021 | 0.0021 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.003 | 0.0056 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0102 | 0.022 |
Onchocerca volvulus | Cathepsin F homolog | 0.0017 | 0.0011 | 0.0024 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0155 | 0.0663 | 0.5974 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0347 | 0.1572 | 0.3001 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.0302 | 0.2114 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.004 | 0.0121 | 0.0121 |
Schistosoma mansoni | hypothetical protein | 0.0347 | 0.1572 | 0.1572 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0046 | 0.1967 |
Echinococcus multilocularis | tumor protein p63 | 0.1689 | 0.7905 | 0.7905 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0024 | 0.0046 | 0.0321 |
Onchocerca volvulus | 0.0017 | 0.0011 | 0.0024 | |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0013 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0011 | 0.0021 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0039 | 0.0116 | 0.1048 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.003 | 0.003 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.1429 | 0.3075 |
Brugia malayi | MH1 domain containing protein | 0.0023 | 0.0039 | 0.0075 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0508 | 0.2331 | 0.4451 |
Schistosoma mansoni | Smad4 | 0.0018 | 0.0019 | 0.0019 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0007 | 0.0302 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.0373 | 0.0373 |
Onchocerca volvulus | 0.0247 | 0.1099 | 0.2364 | |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0039 | 0.0116 | 0.1754 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0116 | 0.025 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0039 | 0.0083 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0043 | 0.0133 | 0.201 |
Echinococcus granulosus | tumor protein p63 | 0.1689 | 0.7905 | 0.7905 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.1429 | 0.3075 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0164 | 0.0313 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0017 | 0.0011 | 0.1042 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0116 | 0.4987 |
Echinococcus granulosus | snurportin 1 | 0.0298 | 0.1338 | 0.1338 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0064 | 0.2727 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0011 | 0.0021 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0039 | 0.0116 | 0.0222 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0011 | 0.0011 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.0116 | 0.0116 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0002 | 0.0075 |
Toxoplasma gondii | cathepsin CPL | 0.0017 | 0.0011 | 0.0208 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0064 | 0.0064 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0011 | 0.0011 |
Schistosoma mansoni | ferritin | 0.0043 | 0.0133 | 0.0133 |
Schistosoma mansoni | hypothetical protein | 0.0298 | 0.1338 | 0.1338 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0078 | 0.0302 | 0.0302 |
Schistosoma mansoni | thyroid hormone receptor | 0.0153 | 0.0653 | 0.0653 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0064 | 0.2727 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Brugia malayi | hypothetical protein | 0.0782 | 0.3626 | 0.6924 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0049 | 0.0164 | 0.2471 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.003 | 0.0056 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0002 | 0.0075 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0508 | 0.2331 | 0.4451 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0164 | 0.0313 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.0164 | 0.1147 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0029 | 0.1236 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0064 | 0.0233 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0039 | 0.0116 | 0.221 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0102 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0116 | 0.0222 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.001 | 0.001 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0.0007 | 0.0063 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0105 | 0.0201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0007 |
Brugia malayi | MH2 domain containing protein | 0.0041 | 0.0126 | 0.024 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0126 | 0.0526 | 0.0526 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.003 | 0.003 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.0592 | 0.0592 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0317 | 0.1429 | 1 |
Loa Loa (eye worm) | Smad1 | 0.0041 | 0.0126 | 0.024 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0007 | 0.0302 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0102 | 0.1941 |
Schistosoma mansoni | hypothetical protein | 0.016 | 0.0685 | 0.0685 |
Echinococcus multilocularis | smad | 0.0041 | 0.0126 | 0.0126 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0116 | 0.1048 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0037 | 0.0105 | 0.5 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.009 | 0.0359 | 0.0686 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.003 | 0.0056 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.0373 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0105 | 0.0201 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0011 | 0.0011 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0064 | 0.0121 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0041 | 0.0126 | 0.0126 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0046 | 0.0046 |
Echinococcus multilocularis | ferritin | 0.0043 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0255 | 0.0487 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0121 | 0.5192 |
Brugia malayi | beta-lactamase | 0.0039 | 0.0116 | 0.0222 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0102 | 0.022 |
Schistosoma mansoni | smad1 5 8 and | 0.0041 | 0.0126 | 0.0126 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0782 | 0.3626 | 0.3626 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0018 | 0.0019 | 0.0035 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0102 | 0.0102 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.0046 | 0.0087 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0007 | 0.0669 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0116 | 0.0222 |
Schistosoma mansoni | hypothetical protein | 0.0347 | 0.157 | 0.157 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.003 | 0.0056 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0102 | 0.0102 |
Schistosoma mansoni | tar DNA-binding protein | 0.1124 | 0.5237 | 0.5237 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.009 | 0.0359 | 0.0686 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.003 | 0.0056 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.003 | 0.003 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0029 | 0.0029 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0002 | 0.0002 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.001 | 0.001 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.0116 | 0.4987 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0153 | 0.0653 | 0.0653 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0011 | 0.0021 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0043 | 0.0133 | 0.201 |
Loa Loa (eye worm) | hypothetical protein | 0.0247 | 0.1099 | 0.2098 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.003 | 0.0056 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0046 | 0.0088 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.0116 | 0.0116 |
Brugia malayi | Smad1 | 0.0041 | 0.0126 | 0.024 |
Schistosoma mansoni | ran | 0.0021 | 0.0029 | 0.0029 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0164 | 0.2471 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0043 | 0.0133 | 0.201 |
Brugia malayi | MH2 domain containing protein | 0.0018 | 0.0019 | 0.0035 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.0302 | 0.2114 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0064 | 0.1209 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0007 | 0.0007 |
Brugia malayi | Inositol-1 | 0.004 | 0.0121 | 0.0231 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.003 | 0.0056 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0082 | 0.0317 | 0.0317 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0037 | 0.0105 | 1 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0155 | 0.0663 | 1 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0011 | 0.0208 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0046 | 0.0046 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.025 | 0.111 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.003 | 0.003 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0011 | 0.0024 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0029 | 0.2738 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0011 | 0.0021 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.003 | 0.0056 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0317 | 0.1429 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0039 | 0.0116 | 0.1754 |
Loa Loa (eye worm) | beta-lactamase | 0.0039 | 0.0116 | 0.0222 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0121 | 0.5192 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0041 | 0.0126 | 0.0126 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.016 | 0.0685 | 0.1309 |
Schistosoma mansoni | lamin | 0.0169 | 0.0729 | 0.0729 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0317 | 0.1429 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0041 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0064 | 0.0121 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.0302 | 0.2114 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0164 | 0.0313 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.0116 | 0.4987 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.003 | 0.0056 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.001 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0107 | 0.0205 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.003 | 0.003 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0161 | 0.0691 | 0.1319 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0102 | 0.4379 |
Brugia malayi | RNA binding protein | 0.1124 | 0.5237 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0011 | 0.0077 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.0275 | 0.0524 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.0233 | 1 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0102 | 0.022 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 0 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 0.22 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 1.59 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 1.61 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 3 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 27 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 96 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition frequency index (IFI) (functional) | = 12.15 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
Percent growth inhibition (functional) | = -3 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 3 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 27 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 96 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
XC50 (functional) | = 6.08 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
XC50 (functional) | = 0.83295 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.