Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | smad | 0.0042 | 0.008 | 0.0089 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0165 | 0.0463 | 0.0519 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0012 | 0.0013 |
Loa Loa (eye worm) | TAR-binding protein | 0.1061 | 0.3254 | 1 |
Echinococcus granulosus | microtubule associated protein 2 | 0.288 | 0.8922 | 1 |
Trichomonas vaginalis | chaperonin, putative | 0.0025 | 0.0025 | 0.0099 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0017 | 0.0003 | 0.015 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0003 | 0.0003 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0165 | 0.0463 | 0.1422 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0616 | 0.1869 | 0.5745 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0029 | 0.0039 | 0.0526 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.0074 | 0.053 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0012 | 0.004 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0063 | 0.0635 |
Schistosoma mansoni | ferritin | 0.0043 | 0.0082 | 0.0092 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0063 | 0.0266 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0063 | 0.0266 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0019 | 0.0007 | 0.0021 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0044 | 0.0086 | 0.0096 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.004 | 0.0072 | 0.0839 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.004 | 0.0072 | 0.0072 |
Onchocerca volvulus | 0.002 | 0.0012 | 0.004 | |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0063 | 0.2463 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0003 | 0.0008 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0019 | 0.0007 | 0.0008 |
Plasmodium vivax | SET domain protein, putative | 0.0094 | 0.0241 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0204 | 0.0626 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0.0951 | 0.4186 |
Schistosoma mansoni | Smad4 | 0.0019 | 0.0007 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0072 | 0.0222 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.004 | 0.0072 | 0.0222 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0186 | 0.0529 | 0.0593 |
Onchocerca volvulus | 0.004 | 0.0072 | 0.0308 | |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0003 | 0.0008 |
Schistosoma mansoni | thyroid hormone receptor | 0.0145 | 0.0399 | 0.0447 |
Schistosoma mansoni | tar DNA-binding protein | 0.1061 | 0.3254 | 0.3647 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0012 | 0.0036 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0073 | 0.0178 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0094 | 0.0241 | 0.0241 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.0072 | 0.0308 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0407 | 0.0456 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0029 | 0.0039 | 0.0044 |
Echinococcus granulosus | lamin | 0.0169 | 0.0477 | 0.0534 |
Echinococcus granulosus | intermediate filament protein | 0.0169 | 0.0477 | 0.0534 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0012 | 0.0013 |
Schistosoma mansoni | survival motor neuron protein | 0.0154 | 0.0428 | 0.048 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0063 | 0.0635 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Schistosoma mansoni | Smad4 | 0.0042 | 0.008 | 0.0089 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.1061 | 0.3254 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.1061 | 0.3254 | 0.3647 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0178 | 0.0546 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0063 | 0.0266 |
Leishmania major | cysteine peptidase A (CPA) | 0.0017 | 0.0003 | 0.0104 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0754 | 0.2299 | 0.2299 |
Schistosoma mansoni | ferritin | 0.0043 | 0.0082 | 0.0092 |
Echinococcus multilocularis | smad | 0.0042 | 0.008 | 0.008 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0094 | 0.0241 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0012 | 0.0013 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0039 | 0.0526 |
Onchocerca volvulus | 0.0169 | 0.0477 | 0.2092 | |
Schistosoma mansoni | hypothetical protein | 0.0508 | 0.1532 | 0.1717 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0003 | 0.011 |
Onchocerca volvulus | 0.0745 | 0.2269 | 1 | |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.0003 | 0.0008 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.0003 | 0.0008 |
Schistosoma mansoni | inositol monophosphatase | 0.0041 | 0.0076 | 0.0085 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0322 | 0.0951 | 1 |
Brugia malayi | hypothetical protein | 0.0754 | 0.2299 | 0.7065 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0063 | 0.0266 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.0072 | 0.0081 |
Brugia malayi | Smad1 | 0.0042 | 0.008 | 0.0245 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0025 | 0.0025 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0012 | 0.0036 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0.0951 | 0.4186 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0407 | 0.1249 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0029 | 0.0039 | 0.016 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0072 | 0.4704 |
Echinococcus multilocularis | lamin dm0 | 0.0169 | 0.0477 | 0.0477 |
Onchocerca volvulus | 0.0169 | 0.0477 | 0.2092 | |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0076 | 0.0187 | 0.0209 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.288 | 0.8922 | 0.8922 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0073 | 0.0178 | 0.7369 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0044 | 0.0086 | 0.0366 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0.0951 | 0.4186 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0076 | 0.0187 | 0.0209 |
Mycobacterium ulcerans | beta-lactamase | 0.004 | 0.0072 | 0.0839 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0073 | 0.0178 | 0.241 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0039 | 0.0119 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0012 | 0.0036 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0003 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0036 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.004 | 0.0072 | 0.0839 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.004 | 0.0072 | 0.0981 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.004 | 0.0072 | 0.0308 |
Brugia malayi | MH1 domain containing protein | 0.0023 | 0.0021 | 0.0065 |
Brugia malayi | AMP-binding enzyme family protein | 0.0098 | 0.0255 | 0.0784 |
Mycobacterium ulcerans | hypothetical protein | 0.004 | 0.0072 | 0.0839 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0012 | 0.0012 |
Schistosoma mansoni | smad | 0.0019 | 0.0007 | 0.0008 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0124 | 0.0336 | 0.0336 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0464 | 0.1395 | 0.4288 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0072 | 0.0222 |
Schistosoma mansoni | apoferritin-2 | 0.0043 | 0.0082 | 0.0092 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0042 | 0.008 | 0.0089 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0098 | 0.0255 | 0.5414 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0012 | 0.0036 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0165 | 0.0463 | 0.0463 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0012 | 0.0013 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0098 | 0.0255 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0147 | 0.0407 | 0.1249 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0187 | 0.1942 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0098 | 0.0255 | 0.5414 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0003 | 0.0173 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0187 | 0.0209 |
Plasmodium vivax | hypothetical protein, conserved | 0.004 | 0.0072 | 0.2999 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.004 | 0.0072 | 0.0981 |
Loa Loa (eye worm) | nuclear factor I | 0.0023 | 0.0021 | 0.0065 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0072 | 0.0308 |
Mycobacterium ulcerans | lipase LipD | 0.004 | 0.0072 | 0.0839 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0157 | 0.0439 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0003 | 0.0008 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0029 | 0.0039 | 0.1521 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0407 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0072 | 0.0222 |
Schistosoma mansoni | inositol monophosphatase | 0.0041 | 0.0076 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0039 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.0467 | 0.1436 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0012 | 0.0013 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0041 | 0.0076 | 0.0085 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0012 | 0.0036 |
Brugia malayi | MH2 domain containing protein | 0.0042 | 0.008 | 0.0245 |
Schistosoma mansoni | tar DNA-binding protein | 0.1061 | 0.3254 | 0.3647 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0025 | 0.0025 | 0.0077 |
Mycobacterium ulcerans | hypothetical protein | 0.0098 | 0.0255 | 0.5414 |
Schistosoma mansoni | ferritin | 0.0043 | 0.0082 | 0.0092 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0012 | 0.0036 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0091 | 0.0232 | 0.0712 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.0745 | 0.229 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0072 | 0.0222 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0.0951 | 0.4186 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0256 | 0.0745 | 0.0835 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0029 | 0.0039 | 0.0526 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0012 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0194 | 0.0596 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0039 | 0.0119 |
Echinococcus multilocularis | ferritin | 0.0043 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0241 | 0.0741 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0098 | 0.0255 | 0.3459 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 0.0428 | 0.048 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0012 | 0.0036 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0043 | 0.0082 | 0.1118 |
Onchocerca volvulus | 0.0094 | 0.0241 | 0.1053 | |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.0477 | 0.1465 |
Loa Loa (eye worm) | hypothetical protein | 0.0754 | 0.2299 | 0.7065 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0178 | 0.0546 |
Schistosoma mansoni | smad | 0.0042 | 0.008 | 0.0089 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0186 | 0.0529 | 0.1627 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0072 | 0.4704 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0039 | 0.1521 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.0076 | 0.4912 |
Loa Loa (eye worm) | beta-lactamase | 0.004 | 0.0072 | 0.0222 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0019 | 0.0007 | 0.0023 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0094 | 0.0241 | 0.027 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0187 | 0.0574 |
Onchocerca volvulus | 0.0029 | 0.0039 | 0.016 | |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0043 | 0.0082 | 0.1092 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0012 | 0.0013 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0012 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0021 | 0.0065 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0147 | 0.0407 | 0.1249 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0029 | 0.0039 | 0.2524 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0154 | 0.0428 | 0.1316 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0025 | 0.0025 | 0.1638 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0012 | 0.0036 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0036 | 0.0062 | 0.0844 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.0076 | 0.4912 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0012 | 0.0013 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0025 | 0.0025 | 0.0077 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0012 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0178 | 0.0546 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0044 | 0.0086 | 0.0366 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0194 | 0.0596 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0063 | 0.0266 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0072 | 0.0981 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0041 | 0.0076 | 0.0322 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0094 | 0.0241 | 0.0241 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0754 | 0.2299 | 0.2577 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0041 | 0.0076 | 0.3131 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.004 | 0.0072 | 0.0981 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0.0951 | 0.4186 |
Echinococcus multilocularis | expressed protein | 0.0043 | 0.0082 | 0.0082 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0149 | 0.0414 | 0.0464 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0186 | 0.0529 | 0.1627 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0012 | 0.0036 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0012 | 0.0036 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0154 | 0.6026 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0073 | 0.0178 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0036 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0098 | 0.0255 | 0.5414 |
Mycobacterium leprae | conserved hypothetical protein | 0.004 | 0.0072 | 0.0839 |
Trichomonas vaginalis | set domain proteins, putative | 0.0745 | 0.2269 | 1 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0029 | 0.0039 | 0.1521 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0043 | 0.0082 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0063 | 0.4087 |
Schistosoma mansoni | apoferritin-2 | 0.0043 | 0.0082 | 0.0092 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0098 | 0.0255 | 0.2663 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0187 | 0.1942 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0029 | 0.0039 | 0.1609 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0098 | 0.0255 | 0.5414 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0157 | 0.0439 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0098 | 0.0255 | 0.0784 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0029 | 0.0039 | 0.0526 |
Echinococcus granulosus | tar DNA binding protein | 0.1061 | 0.3254 | 0.3647 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.0072 | 0.0222 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0012 | 0.0036 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Trichomonas vaginalis | ferritin, putative | 0.0043 | 0.0082 | 0.0352 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0154 | 0.6026 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0654 | 0.1988 | 0.6108 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0186 | 0.0529 | 0.0593 |
Onchocerca volvulus | 0.0256 | 0.0745 | 0.3275 | |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0029 | 0.0039 | 0.0119 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0003 | 0.0104 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0074 | 0.4177 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0072 | 0.0308 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0012 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.0508 | 0.1532 | 0.1717 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0145 | 0.0399 | 0.0399 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0157 | 0.0439 | 0.5944 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0036 | 0.0062 | 0.0587 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0082 | 0.0204 | 0.0228 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0145 | 0.0401 | 0.0449 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0165 | 0.224 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0165 | 0.224 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0072 | 0.0981 |
Schistosoma mansoni | thyroid hormone receptor | 0.0145 | 0.0399 | 0.0447 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0149 | 0.0414 | 0.0414 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.0003 | 0.0008 |
Schistosoma mansoni | ferritin light chain | 0.0043 | 0.0082 | 0.0092 |
Schistosoma mansoni | Smad4 | 0.0019 | 0.0007 | 0.0008 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0012 | 0.0036 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0076 | 0.0187 | 0.0187 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0147 | 0.0407 | 0.1249 |
Onchocerca volvulus | 0.0098 | 0.0255 | 0.1114 | |
Schistosoma mansoni | ferritin light chain | 0.0043 | 0.0082 | 0.0092 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0029 | 0.0039 | 0.2184 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0098 | 0.0255 | 0.5414 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0098 | 0.0255 | 0.5414 |
Echinococcus granulosus | lamin dm0 | 0.0169 | 0.0477 | 0.0534 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0003 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0255 | 0.0784 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0165 | 0.224 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0036 |
Schistosoma mansoni | microtubule-associated protein tau | 0.288 | 0.8922 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0003 | 0.0003 |
Brugia malayi | intermediate filament protein | 0.0169 | 0.0477 | 0.1465 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0012 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0178 | 0.0546 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.004 | 0.0072 | 0.0981 |
Brugia malayi | TAR-binding protein | 0.1061 | 0.3254 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0012 | 0.0013 |
Brugia malayi | RNA recognition motif domain containing protein | 0.1061 | 0.3254 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0007 | 0.0023 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0098 | 0.0255 | 0.2663 |
Schistosoma mansoni | lamin | 0.0169 | 0.0477 | 0.0534 |
Echinococcus multilocularis | tar DNA binding protein | 0.1061 | 0.3254 | 0.3254 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0012 | 0.0013 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0012 | 0.0013 |
Schistosoma mansoni | hypothetical protein | 0.0124 | 0.0336 | 0.0377 |
Loa Loa (eye worm) | hypothetical protein | 0.0317 | 0.0938 | 0.2882 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0012 | 0.0013 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0.0951 | 0.4186 |
Echinococcus granulosus | tumor protein p63 | 0.1746 | 0.5389 | 0.6039 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0029 | 0.0039 | 0.1609 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0029 | 0.0039 | 0.2524 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.0072 | 0.0222 |
Schistosoma mansoni | smad1 5 8 and | 0.0042 | 0.008 | 0.0089 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0044 | 0.0086 | 0.3551 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.006 | 0.0136 | 0.8844 |
Schistosoma mansoni | tar DNA-binding protein | 0.1061 | 0.3254 | 0.3647 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0169 | 0.0477 | 0.1465 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0012 | 0.004 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0.0951 | 0.4186 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0017 | 0.0003 | 0.015 |
Echinococcus multilocularis | Smad4 | 0.0042 | 0.008 | 0.008 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Brugia malayi | beta-lactamase | 0.004 | 0.0072 | 0.0222 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0322 | 0.0951 | 1 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0042 | 0.008 | 0.0245 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0165 | 0.0463 | 0.0463 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0019 | 0.0007 | 0.0023 |
Schistosoma mansoni | intermediate filament proteins | 0.0169 | 0.0477 | 0.0534 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0616 | 0.1869 | 0.5745 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0003 | 0.0104 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0025 | 0.0025 | 0.0987 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0041 | 0.0076 | 0.0076 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0029 | 0.0039 | 0.0526 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0039 | 0.2524 |
Brugia malayi | MH1 domain containing protein | 0.0042 | 0.008 | 0.0245 |
Schistosoma mansoni | smad1 5 8 and | 0.0042 | 0.008 | 0.0089 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0003 | 0.011 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0003 | 0.0003 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0063 | 0.007 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0025 | 0.0025 | 0.0099 |
Brugia malayi | AMP-binding enzyme family protein | 0.0098 | 0.0255 | 0.0784 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0025 | 0.0025 | 0.0025 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0003 | 0.0003 |
Brugia malayi | MH1 domain containing protein | 0.0023 | 0.0021 | 0.0065 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0407 | 0.0456 |
Echinococcus multilocularis | musashi | 0.0169 | 0.0477 | 0.0477 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0147 | 0.0407 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0036 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0154 | 1 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0025 | 0.0025 | 0.0238 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0012 | 0.0036 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0039 | 0.0526 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.009 | 0.0231 | 0.0258 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0098 | 0.0255 | 1 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0043 | 0.0082 | 0.1092 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0025 | 0.0025 | 0.1417 |
Loa Loa (eye worm) | intermediate filament protein | 0.0169 | 0.0477 | 0.1465 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0039 | 0.0119 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0029 | 0.0039 | 0.0039 |
Echinococcus granulosus | expressed protein | 0.0043 | 0.0082 | 0.0092 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0039 | 0.2524 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.0076 | 0.296 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0012 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0072 | 0.0222 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0025 | 0.0025 | 0.0028 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0003 | 0.0104 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0029 | 0.0039 | 0.0119 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0098 | 0.0255 | 0.5414 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0012 | 0.0013 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0012 | 0.0012 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0029 | 0.0039 | 0.2524 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0012 | 0.0013 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0147 | 0.0407 | 0.0407 |
Schistosoma mansoni | lamin | 0.0169 | 0.0477 | 0.0534 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0165 | 0.0463 | 0.1422 |
Loa Loa (eye worm) | oxidoreductase | 0.0029 | 0.0039 | 0.0119 |
Trypanosoma brucei | hypothetical protein, conserved | 0.004 | 0.0072 | 0.4704 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0063 | 0.0266 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0025 | 0.0025 | 0.1638 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0091 | 0.0232 | 0.0712 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0098 | 0.0255 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0012 | 0.0012 |
Echinococcus multilocularis | geminin | 0.0508 | 0.1532 | 0.1532 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0255 | 0.0784 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0154 | 0.6026 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0012 | 0.0036 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0012 | 0.0036 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.004 | 0.0072 | 0.0081 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0094 | 0.0241 | 0.027 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0012 | 0.0013 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0042 | 0.008 | 0.008 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0029 | 0.0039 | 0.0526 |
Onchocerca volvulus | 0.0029 | 0.0039 | 0.016 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.0003 | 0.0008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0063 | 0.4087 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0003 | 0.0008 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0322 | 0.0951 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.004 | 0.0072 | 0.0981 |
Brugia malayi | MH1 domain containing protein | 0.0042 | 0.008 | 0.0245 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0063 | 0.0266 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.004 | 0.0072 | 0.0222 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0029 | 0.0039 | 0.0381 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0012 | 0.0012 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0063 | 0.4087 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0253 | 0.0738 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0098 | 0.0255 | 0.5414 |
Brugia malayi | RNA binding protein | 0.1061 | 0.3254 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0012 | 0.0013 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0464 | 0.1395 | 0.4288 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0012 | 0.0012 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0094 | 0.0241 | 0.027 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0012 | 0.0012 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0052 | 0.011 | 0.7148 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.0074 | 0.0755 |
Onchocerca volvulus | 0.004 | 0.0072 | 0.0308 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0147 | 0.0407 | 0.0407 |
Onchocerca volvulus | 0.0154 | 0.0428 | 0.1878 | |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0147 | 0.0407 | 0.0407 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0019 | 0.0007 | 0.0008 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0094 | 0.0241 | 0.027 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0012 | 0.0036 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0082 | 0.0204 | 0.0204 |
Loa Loa (eye worm) | RNA binding protein | 0.1061 | 0.3254 | 1 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0063 | 0.0063 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0041 | 0.0076 | 0.0768 |
Echinococcus granulosus | geminin | 0.0508 | 0.1532 | 0.1717 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0186 | 0.0529 | 0.0593 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0094 | 0.0241 | 0.027 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0029 | 0.0039 | 0.016 |
Schistosoma mansoni | alpha-glucosidase | 0.0142 | 0.0391 | 0.0438 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0095 | 0.0246 | 0.1074 | |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0012 | 0.0036 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0042 | 0.008 | 0.0089 |
Leishmania major | hypothetical protein, conserved | 0.004 | 0.0072 | 0.2835 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0012 | 0.0013 |
Mycobacterium tuberculosis | Conserved protein | 0.004 | 0.0072 | 0.0981 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0039 | 0.0119 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0041 | 0.0076 | 0.0919 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0012 | 0.0013 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.0076 | 0.4912 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0036 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0165 | 0.224 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0322 | 0.0951 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0012 | 0.0013 |
Brugia malayi | Inositol-1 | 0.0041 | 0.0076 | 0.0232 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.0003 | 0.0008 |
Echinococcus granulosus | ferritin | 0.0043 | 0.0082 | 0.0092 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0003 | 0.0008 |
Brugia malayi | Pre-SET motif family protein | 0.0094 | 0.0241 | 0.0741 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0036 |
Brugia malayi | MH2 domain containing protein | 0.0616 | 0.1869 | 0.5745 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.0026 | 0.0357 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0187 | 0.1942 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0029 | 0.0039 | 0.0119 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0012 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0178 | 0.0546 |
Echinococcus multilocularis | lamin | 0.0169 | 0.0477 | 0.0477 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0186 | 0.0529 | 0.0593 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0044 | 0.0086 | 0.3551 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0019 | 0.0007 | 0.0007 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0169 | 0.0477 | 0.1465 |
Loa Loa (eye worm) | Smad1 | 0.0042 | 0.008 | 0.0245 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0063 | 0.0266 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0029 | 0.0039 | 0.0526 |
Echinococcus multilocularis | tumor protein p63 | 0.1746 | 0.5389 | 0.5389 |
Schistosoma mansoni | tar DNA-binding protein | 0.1061 | 0.3254 | 0.3647 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0098 | 0.0255 | 0.3459 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0041 | 0.0076 | 0.0232 |
Onchocerca volvulus | 0.0029 | 0.0039 | 0.016 | |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0029 | 0.0039 | 0.0044 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0066 | 0.0154 | 1 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0003 | 0.0104 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.004 | 0.0072 | 0.0981 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0003 | 0.0003 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0063 | 0.0193 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0154 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0124 | 0.0336 | 0.0377 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0098 | 0.0255 | 0.2663 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0154 | 1 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0039 | 0.0526 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0039 | 0.2524 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0003 | 0.0003 |
Schistosoma mansoni | smad1 5 8 and | 0.0042 | 0.008 | 0.0089 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0098 | 0.0255 | 0.5414 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0186 | 0.0529 | 0.0529 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0147 | 0.0407 | 0.0456 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0063 | 0.007 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0407 | 0.0456 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0012 | 0.0012 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0025 | 0.0025 | 0.0028 |
Trichomonas vaginalis | esterase, putative | 0.004 | 0.0072 | 0.0308 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0041 | 0.0076 | 0.0322 |
Brugia malayi | Pre-SET motif family protein | 0.0654 | 0.1988 | 0.6108 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.004 | 0.0072 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0255 | 0.0784 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0063 | 0.0266 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0039 | 0.0526 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0025 | 0.0025 | 0.1045 |
Echinococcus granulosus | GPCR family 2 | 0.0147 | 0.0407 | 0.0456 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0012 | 0.0013 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0073 | 0.0178 | 0.3476 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0043 | 0.0082 | 0.1092 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0041 | 0.0076 | 0.0322 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0072 | 0.0222 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0063 | 0.0193 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0029 | 0.0039 | 0.0119 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0029 | 0.0039 | 0.1609 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0019 | 0.0007 | 0.0007 |
Toxoplasma gondii | ABC1 family protein | 0.004 | 0.0072 | 0.2999 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0464 | 0.1395 | 0.4288 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0043 | 0.0082 | 0.1118 |
Schistosoma mansoni | hypothetical protein | 0.0317 | 0.0938 | 0.1051 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0003 | 0.0003 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0042 | 0.008 | 0.008 |
Schistosoma mansoni | alpha-glucosidase | 0.0142 | 0.0391 | 0.0438 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0019 | 0.0007 | 0.0023 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0186 | 0.0529 | 0.0593 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0029 | 0.0039 | 0.0526 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0042 | 0.008 | 0.0089 |
Onchocerca volvulus | 0.0029 | 0.0039 | 0.016 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0017 | 0.0003 | 0.015 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0149 | 0.0414 | 0.1272 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0012 | 0.0036 |
Toxoplasma gondii | propionate-CoA ligase | 0.0029 | 0.0039 | 0.1609 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0063 | 0.2606 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0317 | 0.0938 | 0.2882 |
Mycobacterium leprae | Probable lipase LipE | 0.004 | 0.0072 | 0.0839 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0042 | 0.008 | 0.0245 |
Loa Loa (eye worm) | acetyltransferase | 0.0149 | 0.0414 | 0.1272 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.0072 | 0.0081 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0044 | 0.0086 | 0.3551 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.004 | 0.0072 | 0.0981 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0036 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0012 | 0.004 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0025 | 0.0025 | 0.1045 |
Schistosoma mansoni | ferritin | 0.0043 | 0.0082 | 0.0092 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0003 | 0.0003 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0003 | 0.0104 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0154 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0187 | 0.1942 |
Onchocerca volvulus | 0.004 | 0.0072 | 0.0308 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0003 | 0.0008 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0042 | 0.008 | 0.0245 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0025 | 0.0025 | 0.0077 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0012 | 0.0013 |
Toxoplasma gondii | cathepsin CPL | 0.0017 | 0.0003 | 0.011 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0025 | 0.0025 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0012 | 0.0036 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0019 | 0.0007 | 0.0023 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0012 | 0.0036 |
Echinococcus granulosus | Smad4 | 0.0042 | 0.008 | 0.0089 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0.0951 | 0.4186 |
Loa Loa (eye worm) | hypothetical protein | 0.0464 | 0.1395 | 0.4288 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0012 | 0.0036 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0186 | 0.0529 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0039 | 0.0119 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -1.63 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = -0.85 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = -0.27 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 0 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 25 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 29 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 99 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition frequency index (IFI) (functional) | = 3.03 | Inhibition Frequency Index (IFI) | GSK. | 20485427 |
Percent growth inhibition (functional) | = -5 % | Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 25 % | Percent inhibition of HepG2 growth (at 10 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 29 % | Percent inhibition of P. falciparum Dd2 growth (at 2 uM) | GSK. | 20485427 |
Percent growth inhibition (functional) | = 99 % | Percent inhibition of P. falciparum 3D7 growth (at 2 uM) | GSK. | 20485427 |
XC50 (functional) | = 6.1 | XC50 determination of P. falciparum 3D7 growth | GSK. | 20485427 |
XC50 (functional) | = 0.78978 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.