Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0175 | 0.0183 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0278 | 0.0278 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.0463 | 0.0872 |
Echinococcus multilocularis | dna polymerase eta | 0.0045 | 0.0268 | 0.0279 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0175 | 0.033 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0062 | 0.0117 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0071 | 0.0134 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0069 | 0.0525 | 0.0989 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0463 | 0.0463 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0069 | 0.0525 | 0.0525 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0062 | 0.0117 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0033 | 0.0141 | 0.0141 |
Brugia malayi | Flap endonuclease-1 | 0.0026 | 0.0071 | 0.0134 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0069 | 0.0525 | 0.0525 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | nuclear receptor NHR-88 | 0.0033 | 0.0141 | 0.0265 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0032 | 0.0128 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0033 | 0.0141 | 0.0141 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0182 | 0.0342 |
Schistosoma mansoni | nuclear receptor | 0.0033 | 0.0141 | 0.0141 |
Leishmania major | DNA polymerase eta, putative | 0.0045 | 0.0268 | 0.0504 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0526 | 0.5313 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | DR-78 | 0.0033 | 0.0141 | 0.0265 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0278 | 0.0278 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.0463 | 0.0872 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0033 | 0.0141 | 0.0265 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0278 | 0.0278 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0045 | 0.0268 | 0.0504 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0463 | 0.0463 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0463 | 0.0463 |
Schistosoma mansoni | DNA polymerase eta | 0.0045 | 0.0268 | 0.0268 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0463 | 0.0463 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0069 | 0.0525 | 1 |
Echinococcus granulosus | geminin | 0.017 | 0.158 | 0.158 |
Schistosoma mansoni | nuclear hormone receptor | 0.0033 | 0.0141 | 0.0141 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0069 | 0.0525 | 0.0989 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.158 | 0.158 |
Brugia malayi | nuclear hormone receptor | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | nuclear receptor NHR-88 | 0.0069 | 0.0525 | 0.0989 |
Onchocerca volvulus | 0.0069 | 0.0525 | 1 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0037 | 0.0182 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0972 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0037 | 0.0182 | 0.0182 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0069 | 0.0525 | 0.0525 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0069 | 0.0525 | 0.0525 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0069 | 0.0525 | 0.0989 |
Brugia malayi | conserved hypotetical protein | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0069 | 0.0525 | 0.0989 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0069 | 0.0525 | 0.0989 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0175 | 0.033 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0463 | 0.0463 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0069 | 0.0525 | 0.0525 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0278 | 0.0524 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0069 | 0.0525 | 0.0525 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0069 | 0.0525 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0033 | 0.0141 | 0.0265 |
Plasmodium falciparum | flap endonuclease 1 | 0.0026 | 0.0071 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0278 | 0.0289 |
Brugia malayi | ecdysone receptor | 0.0033 | 0.0141 | 0.0265 |
Schistosoma mansoni | nuclear hormone receptor | 0.0033 | 0.0141 | 0.0141 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0033 | 0.0141 | 0.0141 |
Brugia malayi | RNA binding protein | 0.0064 | 0.0463 | 0.0872 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0936 | 0.9615 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0033 | 0.0141 | 0.0141 |
Schistosoma mansoni | nuclear hormone receptor | 0.0069 | 0.0525 | 0.0525 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0069 | 0.0525 | 0.0546 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0062 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0182 | 0.0342 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0278 | 0.0278 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0033 | 0.0141 | 0.0265 |
Schistosoma mansoni | thyroid hormone receptor | 0.0069 | 0.0525 | 0.0525 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0175 | 0.033 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0069 | 0.0525 | 0.0525 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0069 | 0.0525 | 0.0525 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0182 | 0.0342 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0033 | 0.0141 | 0.0265 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0069 | 0.0525 | 0.0525 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0525 | 0.0989 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0026 | 0.0071 | 0.0134 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0182 | 0.0342 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.0463 | 0.0872 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.158 | 0.158 |
Entamoeba histolytica | Flap nuclease, putative | 0.0026 | 0.0071 | 0.0134 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0175 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0182 | 0.0342 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0033 | 0.0141 | 0.0146 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0037 | 0.0182 | 0.0342 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0032 | 0.0128 | 0.0241 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.0463 | 0.0872 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0069 | 0.0525 | 0.0546 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0175 | 0.0175 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.0463 | 0.0463 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0069 | 0.0525 | 0.0989 |
Brugia malayi | nuclear receptor RXR | 0.0033 | 0.0141 | 0.0265 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0278 | 0.0524 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0069 | 0.0525 | 0.0989 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0069 | 0.0525 | 0.0525 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0062 | 0.0117 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0526 | 0.5313 | 0.5313 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0033 | 0.0141 | 0.0146 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.0463 | 0.0482 |
Echinococcus granulosus | dna polymerase eta | 0.0045 | 0.0268 | 0.0268 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0069 | 0.0525 | 1 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0175 | 0.033 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0037 | 0.0182 | 0.0342 |
Schistosoma mansoni | zinc finger protein | 0.0033 | 0.0141 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0525 | 0.0989 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0278 | 0.0278 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0071 | 0.0134 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0526 | 0.5313 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0526 | 0.5313 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0526 | 0.5313 | 1 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0526 | 0.5313 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0032 | 0.0128 | 0.0241 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0026 | 0.0071 | 0.0074 |
Schistosoma mansoni | nuclear receptor | 0.0033 | 0.0141 | 0.0141 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0069 | 0.0525 | 0.0989 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0026 | 0.0071 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0069 | 0.0525 | 0.0525 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0175 | 0.0175 |
Echinococcus granulosus | flap endonuclease 1 | 0.0026 | 0.0071 | 0.0071 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0069 | 0.0525 | 0.0989 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0033 | 0.0141 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0026 | 0.0071 | 0.1335 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0069 | 0.0525 | 0.0989 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0278 | 0.0289 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0033 | 0.0141 | 0.0146 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0026 | 0.0071 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0069 | 0.0525 | 0.0546 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0175 | 0.033 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0268 | 0.0504 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0037 | 0.0182 | 0.0189 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0182 | 0.0342 |
Echinococcus granulosus | FTZ F1 alpha | 0.0069 | 0.0525 | 0.0525 |
Brugia malayi | steroid hormone receptor | 0.0069 | 0.0525 | 0.0989 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0026 | 0.0071 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0037 | 0.0182 | 0.0342 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0069 | 0.0525 | 0.0989 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0033 | 0.0141 | 0.0146 |
Echinococcus multilocularis | geminin | 0.017 | 0.158 | 0.1643 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0526 | 0.5313 | 0.5525 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0304 | 0.299 | 0.299 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0182 | 0.0342 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0045 | 0.0268 | 0.0504 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0526 | 0.5313 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0033 | 0.0141 | 0.0146 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0526 | 0.5313 | 0.5313 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0069 | 0.0525 | 0.0525 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0525 | 0.0989 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0069 | 0.0525 | 0.0989 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0069 | 0.0525 | 0.0525 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0069 | 0.0525 | 0.0546 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0526 | 0.5313 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0037 | 0.0182 | 0.0342 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0069 | 0.0525 | 0.0546 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0069 | 0.0525 | 0.0989 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0069 | 0.0525 | 0.0525 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0069 | 0.0525 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0525 | 0.0989 |
Brugia malayi | tailless protein | 0.0033 | 0.0141 | 0.0265 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0069 | 0.0525 | 0.0546 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0037 | 0.0182 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Schistosoma mansoni | thyroid hormone receptor | 0.0069 | 0.0525 | 0.0525 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0033 | 0.0141 | 0.0141 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.0463 | 0.0872 |
Schistosoma mansoni | flap endonuclease-1 | 0.0024 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0062 | 0.0117 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0304 | 0.299 | 0.3109 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0033 | 0.0141 | 0.0141 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0033 | 0.0141 | 0.0141 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0062 | 0.0117 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0069 | 0.0525 | 0.0546 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0069 | 0.0525 | 0.0989 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0069 | 0.0525 | 0.0989 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0069 | 0.0525 | 0.0546 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0033 | 0.0141 | 0.0141 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0045 | 0.0268 | 0.0504 |
Brugia malayi | ecdysteroid receptor | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0525 | 0.0989 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0033 | 0.0141 | 0.0141 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0069 | 0.0525 | 0.0989 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0069 | 0.0525 | 0.0525 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0071 | 0.0134 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0069 | 0.0525 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | nuclear receptor NHR-67 | 0.0033 | 0.0141 | 0.0265 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0069 | 0.0525 | 0.0989 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0069 | 0.0525 | 0.0525 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Max fall in blood pressure (functional) | = -14 % | Oral antihypertensive activity in spontaneously hypertensive rats at a dose of 3 mg/kg (po) | ChEMBL. | 1578490 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.