Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | hypothetical protein, conserved | 0.0072 | 0.0824 | 1 |
Brugia malayi | RNA binding protein | 0.0215 | 0.2611 | 0.867 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0378 | 0.1256 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0056 | 0.0632 | 0.0632 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0061 | 0.0203 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.0859 | 0.2853 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0064 | 0.0729 | 0.2708 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0056 | 0.0632 | 0.2099 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0061 | 0.0203 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0824 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.0714 | 0.1705 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0061 | 0.0203 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0061 | 0.0203 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0061 | 0.0146 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0064 | 0.0729 | 0.2708 |
Onchocerca volvulus | 0.0072 | 0.0824 | 0.2259 | |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.1462 | 0.4852 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0061 | 0.0146 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0548 | 0.2035 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0061 | 0.0061 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0824 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0061 | 0.0146 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0174 | 0.0645 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0056 | 0.0632 | 0.1509 |
Schistosoma mansoni | tar DNA-binding protein | 0.0215 | 0.2611 | 0.6232 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0061 | 0.0203 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0036 | 0.0085 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0036 | 0.0119 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0072 | 0.0824 | 0.2735 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0061 | 0.0203 |
Schistosoma mansoni | smad | 0.0008 | 0.0036 | 0.0085 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0061 | 0.0203 |
Brugia malayi | Pre-SET motif family protein | 0.0247 | 0.3012 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0824 | 0.1966 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0824 | 0.2735 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0373 | 0.0891 |
Onchocerca volvulus | 0.0072 | 0.0824 | 0.2259 | |
Onchocerca volvulus | 0.0072 | 0.0824 | 0.2259 | |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0824 | 0.2735 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0061 | 0.0146 |
Schistosoma mansoni | tar DNA-binding protein | 0.0215 | 0.2611 | 0.6232 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0061 | 0.0061 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.021 | 0.021 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0064 | 0.0729 | 0.2421 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.0035 | 0.0373 | 0.0925 | |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.021 | 0.0782 |
Brugia malayi | TAR-binding protein | 0.0215 | 0.2611 | 0.867 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0215 | 0.2611 | 0.867 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0056 | 0.0632 | 0.1509 |
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.1462 | 0.4852 |
Trichomonas vaginalis | set domain proteins, putative | 0.0282 | 0.3438 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0061 | 0.0061 |
Echinococcus multilocularis | tar DNA binding protein | 0.0215 | 0.2611 | 0.2611 |
Mycobacterium ulcerans | beta-lactamase | 0.0072 | 0.0824 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0072 | 0.0824 | 0.5 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0056 | 0.0632 | 0.2348 |
Echinococcus multilocularis | geminin | 0.0168 | 0.2028 | 0.2028 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0378 | 0.0903 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0064 | 0.0729 | 0.0729 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0061 | 0.0203 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0061 | 0.0227 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0215 | 0.2611 | 0.867 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.024 | 0.0796 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0072 | 0.0824 | 0.306 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0034 | 0.0357 | 0.1327 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0061 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0729 | 0.2421 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0036 | 0.0119 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0061 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0121 | 0.0288 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.2028 | 0.4838 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0061 | 0.0146 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0061 | 0.0146 |
Toxoplasma gondii | ABC1 family protein | 0.0072 | 0.0824 | 1 |
Echinococcus multilocularis | smad | 0.0008 | 0.0036 | 0.0036 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0056 | 0.0632 | 0.2348 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0061 | 0.0227 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0061 | 0.0227 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.0036 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0203 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0378 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0059 | 0.067 | 0.067 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0376 | 0.0376 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0548 | 0.2035 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0061 | 0.0227 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0378 | 0.0903 |
Loa Loa (eye worm) | TAR-binding protein | 0.0215 | 0.2611 | 0.867 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0143 | 0.034 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0061 | 0.0203 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0187 | 0.0446 |
Schistosoma mansoni | tar DNA-binding protein | 0.0215 | 0.2611 | 0.6232 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0222 | 0.2693 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0247 | 0.3012 | 1 |
Onchocerca volvulus | 0.0282 | 0.3438 | 1 | |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0061 | 0.0146 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0061 | 0.0203 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0036 | 0.0085 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0052 | 0.0584 | 0.217 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0061 | 0.0203 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0056 | 0.0632 | 0.0632 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0061 | 0.0146 |
Onchocerca volvulus | 0.0056 | 0.0632 | 0.1691 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0059 | 0.067 | 0.2489 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0459 | 0.1524 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0061 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0806 | 0.2677 |
Loa Loa (eye worm) | RNA binding protein | 0.0215 | 0.2611 | 0.867 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0036 | 0.0085 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0072 | 0.0824 | 0.0824 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0824 | 0.5 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0072 | 0.0824 | 0.5 |
Echinococcus granulosus | geminin | 0.0168 | 0.2028 | 0.7531 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0373 | 0.0891 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0061 | 0.0227 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0548 | 0.1819 |
Brugia malayi | Smad1 | 0.0008 | 0.0036 | 0.0119 |
Echinococcus granulosus | tar DNA binding protein | 0.0215 | 0.2611 | 0.9699 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0203 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0824 | 0.2735 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0121 | 0.0288 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.015 | 0.0498 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0052 | 0.0584 | 0.1394 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0061 | 0.0203 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0061 | 0.0203 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0143 | 0.0529 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0373 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0824 | 0.2735 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0061 | 0.0203 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0203 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0824 | 0.2735 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0061 | 0.0203 |
Mycobacterium leprae | Probable lipase LipE | 0.0072 | 0.0824 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0036 | 0.0119 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0036 | 0.0036 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.021 | 0.0502 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0061 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.2028 | 0.4838 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0061 | 0.0061 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0061 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0632 | 0.2099 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0064 | 0.0729 | 0.0729 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0376 | 0.1397 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0036 | 0.0085 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0061 | 0.0146 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0061 | 0.0203 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0061 | 0.0203 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0187 | 0.062 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0378 | 0.5 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.0036 | 0.0119 |
Brugia malayi | beta-lactamase | 0.0072 | 0.0824 | 0.2735 |
Leishmania major | hypothetical protein, conserved | 0.0072 | 0.0824 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0342 | 0.4191 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0203 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0548 | 0.1819 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0036 | 0.0119 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0061 | 0.0203 |
Brugia malayi | mbt repeat family protein | 0.0056 | 0.0632 | 0.2099 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0056 | 0.0632 | 0.1509 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.1462 | 0.4852 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0548 | 0.1308 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0072 | 0.0824 | 0.2735 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0435 | 0.1446 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0824 | 0.2735 |
Schistosoma mansoni | tar DNA-binding protein | 0.0215 | 0.2611 | 0.6232 |
Loa Loa (eye worm) | MBCTL1 | 0.0064 | 0.0729 | 0.2421 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0061 | 0.0203 |
Schistosoma mansoni | tar DNA-binding protein | 0.0215 | 0.2611 | 0.6232 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0061 | 0.0146 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0064 | 0.0729 | 0.174 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0458 | 0.5633 | 1 |
Brugia malayi | mbt repeat family protein | 0.0056 | 0.0632 | 0.2099 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0174 | 0.0415 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0203 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0056 | 0.0632 | 0.1691 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0061 | 0.0061 |
Plasmodium vivax | hypothetical protein, conserved | 0.0072 | 0.0824 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0072 | 0.0824 | 0.2735 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0143 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0203 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0036 | 0.0036 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0061 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0406 | 0.1348 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0405 | 0.1346 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0548 | 0.0548 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0061 | 0.0203 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0036 | 0.0133 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0052 | 0.0584 | 0.0584 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0548 | 0.1308 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0378 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0548 | 0.1308 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0378 | 0.1405 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0061 | 0.0203 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.0036 | 0.0119 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0061 | 0.0227 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0061 | 0.0227 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0061 | 0.0203 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0061 | 0.0203 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0036 | 0.0133 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0824 | 0.1966 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0061 | 0.0146 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0222 | 0.2693 | 0.2693 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0373 | 0.124 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0036 | 0.0133 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0174 | 0.0174 |
Mycobacterium ulcerans | lipase LipD | 0.0072 | 0.0824 | 0.5 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0061 | 0.0203 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0052 | 0.0584 | 0.1394 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0824 | 0.2735 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0061 | 0.0203 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0378 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0203 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0036 | 0.0085 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0548 | 0.0548 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0584 | 0.194 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0061 | 0.0227 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0061 | 0.0061 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0072 | 0.0824 | 0.5 |
Echinococcus granulosus | smad | 0.0008 | 0.0036 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0824 | 0.2735 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (functional) | > 100 uM | Huh7 cytotoxicity for Pf inhibitors | Novartis-GNF Malaria Box. | No reference |
EC50 (functional) | = 1.618 uM | W2 Pf proliferation inhibition | Novartis-GNF Malaria Box. | No reference |
EC50 (functional) | = 8.59 uM | PF proliferation inhibition 3D7 | Novartis-GNF Malaria Box. | No reference |
IFI promiscuity index | = 0 | IFI promiscuity index | Novartis-GNF Malaria Box. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.