Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Entamoeba histolytica | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.3895 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0073 | 0.0663 | 0.0656 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0025 | 0.0057 | 0.062 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.005 | 0.0377 | 0.0373 |
Schistosoma mansoni | multiple ankyrin repeats single kh domain protein | 0.02 | 0.2289 | 0.2283 |
Schistosoma mansoni | chromobox protein | 0.0025 | 0.0057 | 0.0049 |
Schistosoma mansoni | rab6-interacting | 0.0046 | 0.0319 | 0.0312 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0093 | 0.0086 |
Onchocerca volvulus | 0.0053 | 0.0412 | 0.0399 | |
Brugia malayi | Cation transporter family protein | 0.0189 | 0.2144 | 0.2461 |
Plasmodium falciparum | thioredoxin reductase | 0.0105 | 0.1077 | 1 |
Trypanosoma brucei | squalene synthase, putative | 0.0246 | 0.2879 | 1 |
Echinococcus multilocularis | nAChR subunit | 0.0028 | 0.0093 | 0.0086 |
Trypanosoma brucei | protein kinase, putative | 0.0057 | 0.0463 | 0.1609 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0114 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0084 | 0.0802 | 0.2502 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0073 | 0.0663 | 0.0755 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0028 | 0.0093 | 0.0086 |
Trypanosoma brucei | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.1101 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.024 | 0.28 | 0.8905 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.2144 | 0.2461 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0073 | 0.0663 | 0.1998 |
Brugia malayi | Cytochrome P450 family protein | 0.0041 | 0.0258 | 0.0288 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0093 | 0.0099 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.008 | 0.0073 |
Echinococcus granulosus | Chromo domain | 0.0025 | 0.0057 | 0.0049 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0036 | 0.0198 | 0.0689 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.004 | 0.0246 | 0.0853 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0046 | 0.0319 | 0.2571 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0036 | 0.0198 | 0.1389 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0035 | 0.0186 | 0.1266 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0048 | 0.0344 | 0.0339 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0109 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Trichomonas vaginalis | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.0312 |
Echinococcus multilocularis | chromobox protein 2 | 0.0025 | 0.0057 | 0.0049 |
Echinococcus multilocularis | Squalene phytoene synthase | 0.0077 | 0.0713 | 0.0706 |
Loa Loa (eye worm) | acetyltransferase | 0.0163 | 0.1812 | 0.2078 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0084 | 0.0802 | 0.0801 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0035 | 0.0186 | 0.1266 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0084 | 0.0802 | 0.2502 |
Plasmodium falciparum | apurinic/apyrimidinic endonuclease Apn1, putative | 0.0084 | 0.0813 | 0.7408 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0048 | 0.0344 | 0.0339 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0028 | 0.0093 | 0.0086 |
Trypanosoma brucei | cytochrome P450, putative | 0.0029 | 0.0109 | 0.038 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Trypanosoma brucei | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.1101 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.0205 |
Trichomonas vaginalis | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.0312 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Wolbachia endosymbiont of Brugia malayi | S-adenosylmethionine synthetase | 0.0046 | 0.0317 | 0.1965 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0105 | 0.1077 | 0.1232 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0774 | 0.9642 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.005 | 0.0377 | 0.037 |
Brugia malayi | S-adenosylmethionine synthetase | 0.0046 | 0.0317 | 0.0357 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0117 | 0.0111 |
Onchocerca volvulus | 0.0797 | 0.993 | 1 | |
Brugia malayi | Pre-SET motif family protein | 0.07 | 0.8692 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.024 | 0.28 | 0.8905 |
Trichomonas vaginalis | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.0312 |
Trypanosoma brucei | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.1101 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0025 | 0.0057 | 0.0057 |
Schistosoma mansoni | multiple ankyrin repeats single kh domain protein | 0.02 | 0.2289 | 0.2283 |
Onchocerca volvulus | 0.0028 | 0.0093 | 0.0078 | |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0036 | 0.0198 | 0.0321 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0025 | 0.0057 | 0.0057 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.01 | 0.1017 | 0.1011 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0028 | 0.0093 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.0179 |
Echinococcus granulosus | Ankyrin repeat domain containing protein | 0.02 | 0.2289 | 0.2283 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0084 | 0.0802 | 0.0796 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.005 | 0.0377 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0189 | 0.2144 | 0.2139 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0046 | 0.0319 | 0.2571 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0109 | 0.0118 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0319 | 0.0359 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0212 | 0.0206 |
Leishmania major | squalene synthase, putative | 0.0246 | 0.2879 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0036 | 0.0198 | 0.1389 |
Trypanosoma cruzi | phytoene synthase, putative | 0.0077 | 0.0713 | 0.2179 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0022 | 0.0014 | 0.0008 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.1266 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0016 | 0.001 |
Schistosoma mansoni | inositol monophosphatase | 0.0084 | 0.0802 | 0.0796 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0028 | 0.0093 | 0.0086 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0028 | 0.0093 | 0.0086 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0245 | 0.024 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0035 | 0.0186 | 0.0275 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0036 | 0.0198 | 0.0689 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0117 | 0.0111 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0028 | 0.0093 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Chlamydia trachomatis | endonuclease IV | 0.0084 | 0.0813 | 1 |
Trichomonas vaginalis | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.0312 |
Schistosoma mansoni | chromobox protein | 0.0025 | 0.0057 | 0.0049 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.0463 | 0.046 |
Echinococcus multilocularis | chromobox protein 1 | 0.0025 | 0.0057 | 0.0049 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Trichomonas vaginalis | chromobox protein, putative | 0.0025 | 0.0057 | 0.005 |
Trypanosoma brucei | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.1101 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0025 | 0.0057 | 0.0049 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0022 | 0.0014 | 0.0007 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0163 | 0.1812 | 0.1806 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0028 | 0.0093 | 0.0099 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0201 | 0.2308 | 0.2303 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0025 | 0.0057 | 0.0049 |
Trypanosoma cruzi | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.0749 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.023 | 0.2677 | 0.2672 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0028 | 0.0093 | 0.0086 |
Loa Loa (eye worm) | methionine adenosyltransferase | 0.0046 | 0.0317 | 0.0357 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0036 | 0.0198 | 0.1389 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0036 | 0.0198 | 0.1389 |
Trypanosoma brucei | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.1101 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0048 | 0.0344 | 0.2814 |
Brugia malayi | DNA-(Apurinic or apyrimidinic site) lyase | 0.0084 | 0.0813 | 0.0927 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0036 | 0.0198 | 0.0582 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0048 | 0.0344 | 0.2814 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.046 | 0.0522 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0212 | 0.0206 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0025 | 0.0057 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0057 | 0.0057 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0093 | 0.0086 |
Trichomonas vaginalis | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.0312 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0028 | 0.0093 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0057 | 0.0057 |
Trichomonas vaginalis | chromobox protein, putative | 0.0025 | 0.0057 | 0.005 |
Schistosoma mansoni | rab6-interacting | 0.0046 | 0.0319 | 0.0312 |
Onchocerca volvulus | 0.0046 | 0.0319 | 0.0305 | |
Mycobacterium ulcerans | S-adenosylmethionine synthetase | 0.0046 | 0.0317 | 0.3775 |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.4284 | 0.4924 |
Loa Loa (eye worm) | glutathione reductase | 0.0105 | 0.1077 | 0.1232 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0093 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.2613 | 0.3 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0036 | 0.0198 | 0.0191 |
Brugia malayi | Doublecortin family protein | 0.0046 | 0.0319 | 0.0359 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0201 | 0.2308 | 0.2303 |
Leishmania major | trypanothione reductase | 0.0105 | 0.1077 | 0.3494 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Schistosoma mansoni | lipoxygenase | 0.0119 | 0.1252 | 0.1246 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.024 | 0.28 | 0.8905 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Leishmania major | S-adenosylmethionine synthetase | 0.0046 | 0.0317 | 0.0749 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.005 | 0.0377 | 0.0426 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0036 | 0.0198 | 0.0321 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0036 | 0.0198 | 0.0321 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.008 | 0.0074 |
Echinococcus granulosus | geminin | 0.038 | 0.4596 | 0.4592 |
Onchocerca volvulus | 0.0345 | 0.4147 | 0.4167 | |
Echinococcus multilocularis | chromobox protein 1 | 0.0025 | 0.0057 | 0.0049 |
Brugia malayi | hypothetical protein | 0.0136 | 0.1479 | 0.1694 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0081 | 0.0774 | 0.0767 |
Loa Loa (eye worm) | ACC-1 protein | 0.0028 | 0.0093 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.4147 | 0.4767 |
Mycobacterium ulcerans | endonuclease IV | 0.0084 | 0.0813 | 1 |
Echinococcus multilocularis | Ankyrin repeat domain containing protein | 0.02 | 0.2289 | 0.2283 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0024 | 0.0037 | 0.0129 |
Onchocerca volvulus | 0.0225 | 0.2613 | 0.2619 | |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0028 | 0.0093 | 0.0086 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.07 | 0.8692 | 1 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0028 | 0.0093 | 0.0099 |
Trichomonas vaginalis | Heterochromatin protein, putative | 0.0025 | 0.0057 | 0.005 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0093 | 0.0099 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0057 | 0.0463 | 0.1278 |
Onchocerca volvulus | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog | 0.0077 | 0.0713 | 0.0703 |
Entamoeba histolytica | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.3895 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0028 | 0.0093 | 0.0086 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0126 | 0.1342 | 0.1335 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0084 | 0.0802 | 1 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0025 | 0.0057 | 0.0049 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0028 | 0.0093 | 0.0099 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0048 | 0.0344 | 0.2814 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0117 | 0.0111 |
Trichomonas vaginalis | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Onchocerca volvulus | 0.0028 | 0.0093 | 0.0078 | |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0319 | 0.0312 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0028 | 0.0093 | 0.0086 |
Plasmodium falciparum | S-adenosylmethionine synthetase | 0.0046 | 0.0317 | 0.2552 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0028 | 0.0093 | 0.0099 |
Schistosoma mansoni | polycystin 1-related | 0.0046 | 0.0319 | 0.0312 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0028 | 0.0093 | 0.0099 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0028 | 0.0093 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0713 | 0.0813 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0028 | 0.0093 | 0.0086 |
Toxoplasma gondii | endonuclease IV APN | 0.0084 | 0.0813 | 0.7408 |
Brugia malayi | Thioredoxin reductase | 0.0105 | 0.1077 | 0.1232 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0057 | 0.0057 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0025 | 0.0057 | 0.0049 |
Brugia malayi | Isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.0205 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0028 | 0.0093 | 0.0086 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.024 | 0.28 | 0.8905 |
Mycobacterium ulcerans | phytoene synthase, CrtB | 0.0077 | 0.0713 | 0.8748 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.005 | 0.0377 | 0.0426 |
Schistosoma mansoni | chromobox protein | 0.0025 | 0.0057 | 0.0049 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0036 | 0.0198 | 0.1389 |
Echinococcus granulosus | chromobox protein 2 | 0.0025 | 0.0057 | 0.0049 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.0179 |
Onchocerca volvulus | 0.0028 | 0.0093 | 0.0078 | |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0057 | 0.0463 | 0.1278 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0081 | 0.0774 | 0.0767 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0029 | 0.0109 | 0.0118 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0109 | 0.0118 |
Brugia malayi | isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.0205 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.0463 | 0.046 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0022 | 0.0014 | 0.0007 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.008 | 0.0074 |
Trypanosoma brucei | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.1101 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0036 | 0.0198 | 0.0321 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Trichomonas vaginalis | chromobox protein, putative | 0.0025 | 0.0057 | 0.005 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0109 | 0.0118 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0042 | 0.0271 | 0.0264 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0057 | 0.062 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0025 | 0.0057 | 0.0049 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0028 | 0.0093 | 0.0099 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.008 | 0.0074 |
Mycobacterium leprae | PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) | 0.0084 | 0.0813 | 0.2547 |
Toxoplasma gondii | thioredoxin reductase | 0.0105 | 0.1077 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0158 | 0.1753 | 0.1747 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0029 | 0.0109 | 0.117 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.023 | 0.0223 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0774 | 0.0767 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0057 | 0.062 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0028 | 0.0093 | 0.0099 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0025 | 0.0057 | 0.0049 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0057 | 0.0463 | 0.1278 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0036 | 0.0198 | 0.0321 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0084 | 0.0802 | 0.7308 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.01 | 0.1017 | 0.1011 |
Plasmodium vivax | apurinic/apyrimidinic endonuclease Apn1, putative | 0.0084 | 0.0813 | 0.7408 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0057 | 0.0463 | 0.3985 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0267 | 0.3143 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.0179 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.004 | 0.0246 | 0.0491 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0028 | 0.0093 | 0.0086 |
Trypanosoma brucei | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.1101 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.023 | 0.0257 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0028 | 0.0093 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0035 | 0.0186 | 0.0645 |
Schistosoma mansoni | lipoxygenase | 0.0201 | 0.2308 | 0.2303 |
Trichomonas vaginalis | chromobox protein, putative | 0.0025 | 0.0057 | 0.005 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.023 | 0.0257 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.023 | 0.2677 | 0.3074 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0028 | 0.0093 | 0.0099 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0073 | 0.0663 | 0.0755 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0028 | 0.0093 | 0.0086 |
Onchocerca volvulus | 0.0046 | 0.0319 | 0.0305 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0245 | 0.024 |
Onchocerca volvulus | 0.0189 | 0.2144 | 0.2146 | |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0774 | 0.9642 |
Echinococcus granulosus | expressed protein | 0.0419 | 0.5088 | 0.5084 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0025 | 0.0057 | 0.062 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0057 | 0.0463 | 0.0456 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0081 | 0.0774 | 0.0767 |
Brugia malayi | Pre-SET motif family protein | 0.01 | 0.1017 | 0.1163 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.046 | 0.0522 |
Brugia malayi | Cation transporter family protein | 0.0028 | 0.0093 | 0.0099 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0046 | 0.0319 | 0.0312 |
Brugia malayi | hypothetical protein | 0.0106 | 0.1086 | 0.1242 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0267 | 0.3143 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0412 | 0.0405 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0022 | 0.0014 | 0.0007 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0022 | 0.0014 | 0.0007 |
Echinococcus multilocularis | RUN | 0.0046 | 0.0319 | 0.0312 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0093 | 0.0086 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0057 | 0.0463 | 0.0456 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0028 | 0.0093 | 0.0099 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0084 | 0.0802 | 0.2502 |
Trypanosoma cruzi | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.0749 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0028 | 0.0093 | 0.0086 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0028 | 0.0093 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0057 | 0.0049 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0028 | 0.0093 | 0.0086 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0057 | 0.0463 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0189 | 0.2144 | 0.2139 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.023 | 0.2677 | 0.2672 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0245 | 0.024 |
Onchocerca volvulus | 0.0189 | 0.2144 | 0.2146 | |
Echinococcus granulosus | RUN | 0.0046 | 0.0319 | 0.0312 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0048 | 0.0344 | 0.0337 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0036 | 0.0198 | 0.022 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.0463 | 0.046 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0025 | 0.0057 | 0.0049 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0093 | 0.0099 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0028 | 0.0093 | 0.0099 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.005 | 0.0377 | 0.1309 |
Schistosoma mansoni | loxhd1 | 0.0046 | 0.0319 | 0.0312 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0073 | 0.0663 | 0.1998 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0261 | 0.3065 | 0.306 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0043 | 0.0283 | 0.0278 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.004 | 0.0246 | 0.0491 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0057 | 0.0463 | 0.0456 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0057 | 0.0463 | 0.0456 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0114 | 0.0107 |
Toxoplasma gondii | S-adenosyl methionine synthetase | 0.0046 | 0.0317 | 0.2552 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0163 | 0.1812 | 0.1806 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0036 | 0.0198 | 0.1389 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0044 | 0.0293 | 0.2315 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0036 | 0.0198 | 0.0321 |
Schistosoma mansoni | inositol monophosphatase | 0.0084 | 0.0802 | 0.0796 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0028 | 0.0093 | 0.0099 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.01 | 0.1017 | 0.1011 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0093 | 0.0086 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.008 | 0.0073 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0165 | 0.0159 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0041 | 0.0258 | 0.0288 |
Giardia lamblia | S-adenosylmethionine synthetase | 0.0046 | 0.0317 | 0.4479 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.008 | 0.0073 |
Schistosoma mansoni | chromobox protein | 0.0025 | 0.0057 | 0.0049 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0028 | 0.0093 | 0.0086 |
Echinococcus multilocularis | S adenosylmethionine synthase type 1 | 0.0046 | 0.0317 | 0.031 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0073 | 0.0663 | 0.0656 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0057 | 0.0463 | 0.1609 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0028 | 0.0093 | 0.0099 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0073 | 0.0663 | 0.0656 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0036 | 0.0198 | 0.0321 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.3065 | 0.3521 |
Onchocerca volvulus | Putative nachr subunit | 0.0028 | 0.0093 | 0.0078 |
Trichomonas vaginalis | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.0312 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0035 | 0.0186 | 0.0275 |
Echinococcus granulosus | S adenosylmethionine synthase type 1 | 0.0046 | 0.0317 | 0.031 |
Trypanosoma cruzi | squalene synthase, putative | 0.0246 | 0.2879 | 1 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.005 | 0.0377 | 0.465 |
Onchocerca volvulus | 0.0189 | 0.2144 | 0.2146 | |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.0713 | 0.0706 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.01 | 0.1017 | 0.1011 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0774 | 0.9642 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.005 | 0.0377 | 0.0373 |
Loa Loa (eye worm) | ACC-1 protein | 0.0028 | 0.0093 | 0.0099 |
Brugia malayi | hypothetical protein | 0.0345 | 0.4147 | 0.4767 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0028 | 0.0093 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0319 | 0.0359 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0212 | 0.0206 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0046 | 0.0319 | 0.0312 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0036 | 0.0198 | 0.2285 |
Brugia malayi | hypothetical protein | 0.0225 | 0.2613 | 0.3 |
Echinococcus granulosus | chromobox protein 1 | 0.0025 | 0.0057 | 0.0049 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0046 | 0.0319 | 0.0312 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.005 | 0.0377 | 0.1309 |
Echinococcus granulosus | Chromobox protein 3 | 0.0025 | 0.0057 | 0.0049 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0097 | 0.097 | 0.0964 |
Loa Loa (eye worm) | hypothetical protein | 0.0175 | 0.1978 | 0.2269 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0025 | 0.0057 | 0.0049 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0084 | 0.0802 | 0.0801 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0046 | 0.0319 | 0.0312 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0075 | 0.069 | 0.2156 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0093 | 0.0099 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0036 | 0.0198 | 0.0191 |
Mycobacterium tuberculosis | Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) | 0.0084 | 0.0813 | 0.2547 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.01 | 0.1017 | 0.9414 |
Treponema pallidum | S-adenosylmethionine synthetase | 0.0046 | 0.0317 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Brugia malayi | CHD4 protein | 0.0025 | 0.0057 | 0.0057 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0025 | 0.0057 | 0.0049 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.0463 | 0.046 |
Onchocerca volvulus | 0.0126 | 0.1342 | 0.1337 | |
Brugia malayi | Heterochromatin protein 1 | 0.0025 | 0.0057 | 0.0057 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0093 | 0.0086 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0057 | 0.0463 | 0.1278 |
Brugia malayi | hypothetical protein | 0.0081 | 0.0774 | 0.0883 |
Brugia malayi | Hypothetical 29.7 kDa protein C05D11.5 in chromosome III | 0.0022 | 0.0016 | 0.001 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0073 | 0.0663 | 0.2302 |
Brugia malayi | glutathione reductase | 0.0105 | 0.1077 | 0.1232 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.005 | 0.0377 | 0.465 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.0774 | 0.9642 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0025 | 0.0057 | 0.0057 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.008 | 0.0074 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0802 | 1 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0036 | 0.0198 | 0.0321 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0036 | 0.0198 | 0.0321 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0093 | 0.0086 |
Mycobacterium tuberculosis | Probable reductase | 0.024 | 0.28 | 0.8905 |
Plasmodium vivax | SET domain protein, putative | 0.01 | 0.1017 | 0.9414 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0084 | 0.0802 | 0.9872 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.2144 | 0.2461 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0028 | 0.0093 | 0.0099 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.005 | 0.0377 | 0.037 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.005 | 0.0377 | 0.0966 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0151 | 0.0145 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.046 | 0.0522 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0084 | 0.0802 | 0.2787 |
Trichomonas vaginalis | chromobox protein, putative | 0.0025 | 0.0057 | 0.005 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0057 | 0.0463 | 0.1278 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0057 | 0.0463 | 0.1278 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0319 | 0.0359 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0212 | 0.0206 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0036 | 0.0198 | 0.0321 |
Loa Loa (eye worm) | LGC-31 protein | 0.0028 | 0.0093 | 0.0099 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0035 | 0.0186 | 0.0645 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0025 | 0.0057 | 0.0057 |
Echinococcus multilocularis | Chromo domain | 0.0025 | 0.0057 | 0.0049 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0084 | 0.0802 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.2613 | 0.3 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Plasmodium falciparum | glutathione reductase | 0.0036 | 0.0198 | 0.1389 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0212 | 0.0206 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0163 | 0.1812 | 0.2078 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0036 | 0.0198 | 0.0689 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0093 | 0.0099 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0037 | 0.0212 | 0.1521 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0105 | 0.1077 | 0.1071 |
Trypanosoma brucei | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.1101 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0027 | 0.0075 | 0.0078 |
Echinococcus multilocularis | geminin | 0.038 | 0.4596 | 0.4592 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0028 | 0.0093 | 0.0086 |
Trichomonas vaginalis | set domain proteins, putative | 0.0797 | 0.993 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0057 | 0.0057 |
Trichomonas vaginalis | chromobox protein, putative | 0.0025 | 0.0057 | 0.005 |
Trypanosoma cruzi | squalene synthase, putative | 0.0246 | 0.2879 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0105 | 0.1077 | 0.1071 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0035 | 0.0186 | 0.0275 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0057 | 0.005 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0035 | 0.0186 | 0.0179 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0028 | 0.0093 | 0.0099 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.0179 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0046 | 0.0319 | 0.0312 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.024 | 0.28 | 0.8905 |
Loa Loa (eye worm) | helicase | 0.0025 | 0.0057 | 0.0057 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0261 | 0.3065 | 0.306 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0022 | 0.0014 | 0.0008 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Brugia malayi | Valyl-tRNA synthetase | 0.0025 | 0.0057 | 0.0057 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0319 | 0.0359 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0073 | 0.0663 | 0.1998 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0027 | 0.0075 | 0.0078 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0028 | 0.0093 | 0.0086 |
Plasmodium vivax | glutathione reductase, putative | 0.0105 | 0.1077 | 1 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0028 | 0.0093 | 0.0086 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0028 | 0.0093 | 0.0099 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0042 | 0.0271 | 0.0264 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.023 | 0.2677 | 0.2672 |
Brugia malayi | hypothetical protein | 0.0261 | 0.3065 | 0.3521 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.0179 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0036 | 0.0198 | 0.0321 |
Schistosoma mansoni | S-adenosylmethionine synthetase | 0.0046 | 0.0317 | 0.031 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0105 | 0.1077 | 0.3494 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0025 | 0.0057 | 0.062 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1017 | 0.1163 |
Schistosoma mansoni | hypothetical protein | 0.038 | 0.4596 | 0.4592 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0028 | 0.0093 | 0.0086 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.005 | 0.0377 | 0.037 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0073 | 0.0663 | 0.8243 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0036 | 0.0198 | 0.0193 |
Loa Loa (eye worm) | inositol-1 | 0.0084 | 0.0802 | 0.0916 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0028 | 0.0093 | 0.0099 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0105 | 0.1077 | 0.3393 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.0412 | 0.0466 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0035 | 0.0186 | 0.0542 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0267 | 0.3143 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0025 | 0.0057 | 0.005 |
Entamoeba histolytica | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.3895 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.005 | 0.0377 | 0.0966 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0035 | 0.0186 | 0.1266 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.005 | 0.0377 | 0.0966 |
Leishmania major | S-adenosylmethionine synthetase | 0.0046 | 0.0317 | 0.0749 |
Echinococcus multilocularis | expressed protein | 0.0419 | 0.5088 | 0.5084 |
Schistosoma mansoni | hypothetical protein | 0.038 | 0.4596 | 0.4592 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0036 | 0.0198 | 0.0321 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0036 | 0.0198 | 0.2285 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0212 | 0.0206 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0028 | 0.0093 | 0.0086 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0028 | 0.0093 | 0.0086 |
Echinococcus granulosus | chromobox protein 1 | 0.0025 | 0.0057 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0813 | 0.0927 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0022 | 0.0014 | 0.0007 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.024 | 0.28 | 0.8905 |
Plasmodium falciparum | thioredoxin reductase | 0.0036 | 0.0198 | 0.1389 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0028 | 0.0093 | 0.0086 |
Mycobacterium tuberculosis | Probable phytoene synthase PhyA | 0.0077 | 0.0713 | 0.2228 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0036 | 0.0198 | 0.0193 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0036 | 0.0198 | 0.0689 |
Trypanosoma brucei | trypanothione reductase | 0.0105 | 0.1077 | 0.3742 |
Plasmodium falciparum | glutathione reductase | 0.0105 | 0.1077 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0057 | 0.0463 | 0.0456 |
Onchocerca volvulus | 0.0225 | 0.2613 | 0.2619 | |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0084 | 0.0802 | 0.0796 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Brugia malayi | Protein cec-1. | 0.0025 | 0.0057 | 0.0057 |
Brugia malayi | Cation transporter family protein | 0.0028 | 0.0093 | 0.0099 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0028 | 0.0093 | 0.0086 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.005 | 0.0377 | 0.0966 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0802 | 1 | 1 |
Loa Loa (eye worm) | doublecortin family protein | 0.0046 | 0.0319 | 0.0359 |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0225 | 0.2613 | 0.3 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0057 | 0.0463 | 0.0525 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0036 | 0.0198 | 0.0321 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.0412 | 0.0405 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0022 | 0.0014 | 0.0008 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0245 | 0.024 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.01 | 0.1017 | 0.1011 |
Brugia malayi | chromobox protein homolog 3 | 0.0025 | 0.0057 | 0.0057 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0093 | 0.0099 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0036 | 0.0198 | 0.2285 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0084 | 0.0802 | 0.0801 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0025 | 0.0057 | 0.0041 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0044 | 0.0293 | 0.3567 |
Trypanosoma brucei | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.1101 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0267 | 0.3143 | 1 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0044 | 0.0293 | 0.3591 |
Brugia malayi | SET domain containing protein | 0.0029 | 0.0104 | 0.0111 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0105 | 0.1077 | 1 |
Echinococcus granulosus | Squalene phytoene synthase | 0.0077 | 0.0713 | 0.0706 |
Brugia malayi | Inositol-1 | 0.0084 | 0.0802 | 0.0916 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.046 | 0.0522 |
Leishmania major | hypothetical protein, conserved | 0.0077 | 0.0713 | 0.2179 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0025 | 0.0057 | 0.005 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0046 | 0.0319 | 0.0312 |
Plasmodium vivax | S-adenosylmethionine synthetase, putative | 0.0046 | 0.0317 | 0.2552 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0075 | 0.069 | 0.2156 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0099 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.01 | 0.1017 | 0.1011 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0057 | 0.062 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0036 | 0.0198 | 0.0191 |
Giardia lamblia | GTOR | 0.005 | 0.0377 | 0.6744 |
Echinococcus granulosus | nAChR subunit | 0.0028 | 0.0093 | 0.0086 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0212 | 0.0206 |
Brugia malayi | MAP kinase sur-1 | 0.0057 | 0.0463 | 0.0525 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0245 | 0.024 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 11 uM | Inhibition constants of MT Formsof rat Novikoff Ascitic Hepatomae using ATP as the variable substrate ;Inhibition is competitive type | ChEMBL. | 3498043 |
Ki (binding) | = 16 uM | Inhibition constants of M-2 Formsof rat methionine adenosyltransferase using ATP as the variable substrate ;Inhibition is competitive type | ChEMBL. | 3498043 |
Ki (binding) | = 26 uM | Inhibition constants of M-2 Formsof rat methionine adenosyltransferase using Methionine as the variable substrate ;Inhibition is competitive type | ChEMBL. | 3498043 |
Ki (binding) | = 38 uM | Inhibition constants of MT Formsof rat Novikoff Ascitic Hepatomae using Methionine as the variable substrate ;Inhibition is non competitive inhibition | ChEMBL. | 3498043 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.