Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.9228 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.7897 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.7897 | 0.8527 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.7897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.3818 | 0.4014 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.4163 | 0.4395 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.7897 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.2951 | 0.3737 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.7897 | 0.8527 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0535 | 0.0678 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.724 | 0.9167 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0535 | 0.0678 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.7897 | 0.7673 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.7897 | 0.7673 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.2951 | 0.3737 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.7886 | 0.9985 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.7897 | 0.8527 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0191 | 0.0241 |
Brugia malayi | RNA binding protein | 0.0062 | 0.7897 | 0.7673 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.7897 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.7897 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.724 | 0.9167 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.3391 | 0.3541 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.3378 | 0.2673 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.7897 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0535 | 0.0678 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.7897 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.