Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.1144 | 0.1144 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3341 | 0.3341 |
Brugia malayi | TAR-binding protein | 0.0067 | 0.3341 | 0.6439 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.1168 | 0.2275 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0092 | 0.4892 | 0.4892 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.184 | 0.184 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0018 | 0.0415 | 0.5 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0038 | 0.1621 | 0.1621 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative | 0.0011 | 0.0038 | 0.0074 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0356 | 0.0356 |
Toxoplasma gondii | thioredoxin reductase | 0.0051 | 0.2393 | 0.4852 |
Echinococcus granulosus | high affinity cAMP specific 3'5' cyclic | 0.0011 | 0.0038 | 0.0038 |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 0.3341 | 0.3341 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.1144 | 0.1144 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0546 | 0.2155 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.1144 | 0.2228 |
Schistosoma mansoni | camp-specific cyclic nucleotide phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Echinococcus multilocularis | geminin | 0.0178 | 1 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0356 | 0.0356 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0012 | 0.0057 | 0.0078 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0356 | 0.0356 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0011 | 0.0038 | 0.0038 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.1144 | 0.2278 |
Plasmodium falciparum | glutathione reductase | 0.0051 | 0.2393 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1504 | 0.293 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0011 | 0.0038 | 0.0038 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.5134 | 0.5134 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0415 | 0.1599 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0018 | 0.0415 | 0.0415 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0546 | 0.0546 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0011 | 0.0038 | 0.0074 |
Echinococcus multilocularis | high affinity cAMP specific 3',5' cyclic | 0.0011 | 0.0038 | 0.0038 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0081 | 0.4219 | 0.4219 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0415 | 0.1599 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0018 | 0.0415 | 0.1599 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0092 | 0.4892 | 0.4892 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 0.3341 | 0.3341 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0356 | 0.0356 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0018 | 0.0415 | 0.1599 |
Leishmania major | trypanothione reductase | 0.0051 | 0.2393 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0018 | 0.0415 | 0.1599 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0018 | 0.0415 | 0.7418 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0546 | 0.0546 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.1271 | 0.1271 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0019 | 0.0497 | 0.0958 |
Echinococcus granulosus | high affinity cgmp specific 3' 5' cyclic | 0.0011 | 0.0038 | 0.0038 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0011 | 0.0042 | 0.0042 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.5134 | 0.5134 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.1144 | 0.1144 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0546 | 0.5 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.5134 | 0.5134 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0081 | 0.4219 | 0.8131 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 0.3341 | 0.6508 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.2494 | 0.4807 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.278 | 0.5649 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0415 | 0.1599 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 0.3341 | 0.6439 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.1271 | 0.1271 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.1144 | 0.4694 |
Loa Loa (eye worm) | calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase | 0.0011 | 0.0038 | 0.0075 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0092 | 0.4892 | 0.4892 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0018 | 0.0415 | 0.7418 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.1144 | 0.2228 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0546 | 0.1052 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0018 | 0.0415 | 0.1599 |
Brugia malayi | Bromodomain containing protein | 0.003 | 0.1144 | 0.2204 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0356 | 0.0356 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.2494 | 0.4858 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0356 | 0.0356 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0546 | 0.2155 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0011 | 0.0038 | 0.0074 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0356 | 0.0356 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0116 | 0.6272 | 0.8837 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0546 | 0.1064 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0415 | 0.1599 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0356 | 0.0356 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0011 | 0.0038 | 0.0074 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0081 | 0.4219 | 0.8219 |
Echinococcus multilocularis | high affinity cgmp specific 3' 5' cyclic | 0.0011 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0038 | 0.0075 |
Onchocerca volvulus | 0.003 | 0.1168 | 1 | |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0546 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.1271 | 0.1271 |
Onchocerca volvulus | Alhambra homolog | 0.003 | 0.1144 | 0.9792 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0546 | 0.1046 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.1144 | 0.2204 |
Echinococcus granulosus | peregrin | 0.003 | 0.1144 | 0.1144 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0356 | 0.0685 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.1168 | 0.2251 |
Plasmodium falciparum | thioredoxin reductase | 0.0018 | 0.0415 | 0.1599 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.0011 | 0.0038 | 0.0074 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0415 | 0.1599 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0081 | 0.4219 | 0.4219 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0415 | 0.1599 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0415 | 0.1599 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3341 | 0.3341 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1504 | 0.1504 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0546 | 0.1046 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0051 | 0.2393 | 1 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0097 | 0.5134 | 0.9893 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0356 | 0.0685 |
Loa Loa (eye worm) | glutathione reductase | 0.0051 | 0.2393 | 0.4662 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0018 | 0.0415 | 0.08 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.5134 | 0.5134 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0051 | 0.2393 | 0.4662 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0092 | 0.4892 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0051 | 0.2393 | 0.2393 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.1504 | 0.2899 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0415 | 0.1599 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0092 | 0.4892 | 0.4892 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.1271 | 0.1271 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0116 | 0.6272 | 0.8837 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.5134 | 0.5134 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0546 | 0.0546 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0546 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0116 | 0.6272 | 0.8837 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0097 | 0.5189 | 0.5189 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0018 | 0.0415 | 0.1599 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0546 | 0.2155 |
Plasmodium falciparum | thioredoxin reductase | 0.0051 | 0.2393 | 1 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0018 | 0.0415 | 0.0415 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.3037 | 0.5916 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.2494 | 0.4807 |
Schistosoma mansoni | jumonji domain containing protein | 0.0077 | 0.3992 | 0.3992 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3341 | 0.3341 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0546 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0064 | 0.3189 | 0.3189 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0128 | 0.7043 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 0.3341 | 0.6508 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0356 | 0.0356 |
Schistosoma mansoni | calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0011 | 0.0042 | 0.0042 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0116 | 0.6272 | 0.8837 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0038 | 0.0075 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0018 | 0.0415 | 0.0776 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0011 | 0.0038 | 0.0074 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3341 | 0.3341 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0018 | 0.0415 | 0.1599 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0415 | 0.1599 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.1144 | 0.2278 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0018 | 0.0415 | 0.0776 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.184 | 0.184 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0546 | 0.2155 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 0.3341 | 0.6508 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.4892 | 0.9529 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0017 | 0.0395 | 0.0395 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2414 | 0.4702 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Plasmodium falciparum | glutathione reductase | 0.0018 | 0.0415 | 0.1599 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.1518 | 0.1518 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0013 | 0.0136 | 0.0263 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0051 | 0.2393 | 0.2985 |
Brugia malayi | glutathione reductase | 0.0051 | 0.2393 | 0.4612 |
Brugia malayi | RNA binding protein | 0.0067 | 0.3341 | 0.6439 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.5134 | 0.5134 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0356 | 0.0356 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2494 | 0.4858 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.1621 | 0.1621 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0546 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0092 | 0.4892 | 0.4892 |
Plasmodium vivax | hypothetical protein, conserved | 0.0012 | 0.0057 | 0.0078 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0051 | 0.2393 | 1 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0018 | 0.0415 | 0.1599 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0011 | 0.0038 | 0.0038 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0116 | 0.6272 | 0.8837 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.1621 | 0.3157 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0051 | 0.2393 | 0.2393 |
Echinococcus multilocularis | peregrin | 0.003 | 0.1144 | 0.1144 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0018 | 0.0415 | 0.1599 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0356 | 0.0693 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.1621 | 0.1621 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.1168 | 0.1168 |
Brugia malayi | PHD-finger family protein | 0.0011 | 0.005 | 0.0096 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Mycobacterium tuberculosis | Probable reductase | 0.0116 | 0.6272 | 0.8837 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0128 | 0.7043 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0128 | 0.7043 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0128 | 0.7043 | 1 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0011 | 0.0038 | 0.0038 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0018 | 0.0415 | 0.0415 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0546 | 0.0198 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0013 | 0.0136 | 0.0263 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0097 | 0.5134 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.1144 | 0.4694 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0546 | 0.2155 |
Brugia malayi | Thioredoxin reductase | 0.0051 | 0.2393 | 0.4612 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.1144 | 0.1144 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0018 | 0.0415 | 0.1599 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0011 | 0.0038 | 0.0038 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.1144 | 0.2278 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.1621 | 0.3123 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0038 | 0.0075 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0011 | 0.0038 | 0.0038 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0415 | 0.1599 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0018 | 0.0415 | 0.0776 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.005 | 0.0097 |
Brugia malayi | jmjC domain containing protein | 0.0097 | 0.5189 | 1 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0092 | 0.4892 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0051 | 0.2393 | 1 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0356 | 0.0693 |
Loa Loa (eye worm) | PDE1B protein | 0.0011 | 0.0038 | 0.0075 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0546 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0546 | 0.2155 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.5134 | 0.5134 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3341 | 0.3341 |
Plasmodium vivax | glutathione reductase, putative | 0.0051 | 0.2393 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0546 | 0.0546 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0415 | 0.1599 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0415 | 0.1599 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0097 | 0.5189 | 0.5189 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.