TDR Targets

Basic information

Technical information

TDR Targets ID: 610268
Name: BAS 00935766
MW: 363.405 | Formula: C19H25NO6
H donors: 1 H acceptors: 1 LogP: 1.9 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: O=C(C1OC2OC(OC2C2C1OC(O2)(C)C)(C)C)Nc1ccc(cc1)C
InChi: 1S/C19H25NO6/c1-10-6-8-11(9-7-10)20-16(21)14-12-13(24-18(2,3)23-12)15-17(22-14)26-19(4,5)25-15/h6-9,12-15,17H,1-5H3,(H,20,21)
InChiKey: CJWNRZVRQCFWAU-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

TULIP028519

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	camp-specific 35-cyclic phosphodiesterase	0.0011	0.0101	0.0101
Schistosoma mansoni	tar DNA-binding protein	0.0066	0.3377	0.3377
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0016	0.0408	0.0356
Echinococcus multilocularis	cAMP specific 3',5' cyclic phosphodiesterase	0.0081	0.4315	0.4284
Schistosoma mansoni	high-affinity cgmp-specific 35-cyclic phosphodiesterase	0.0011	0.0101	0.0101
Schistosoma mansoni	cgmp-dependent 35-cyclic phosphodiesterase	0.0011	0.0101	0.0101
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.002	0.0597	0.5
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.002	0.0597	0.5
Plasmodium vivax	hypothetical protein, conserved	0.0029	0.1188	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.1188	0.2262
Schistosoma mansoni	cpg binding protein	0.0032	0.1318	0.1318
Echinococcus granulosus	cpg binding protein	0.0032	0.1318	0.1271
Schistosoma mansoni	coup transcription factor	0.0011	0.0054	0.0054
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0011	0.0054	0.0104
Echinococcus granulosus	high affinity cAMP specific 3'5' cyclic	0.0011	0.0101	0.0047
Brugia malayi	nuclear hormone receptor	0.0011	0.0054	0.0104
Trypanosoma brucei	cAMP-specific phosphodiesterase	0.0011	0.0101	0.1693
Schistosoma mansoni	camp-specific cyclic nucleotide phosphodiesterase	0.0011	0.0101	0.0101
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0408	0.0705
Echinococcus granulosus	calcium:calmodulin dependent 3'5' cyclic	0.0011	0.0101	0.0047
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0016	0.0408	0.0356
Echinococcus granulosus	dual 3'5' cyclic AMP and GMP phosphodiesterase	0.0011	0.0101	0.0047
Giardia lamblia	CAMP-specific 3,5-cyclic phosphodiesterase 4B	0.0093	0.4993	1
Echinococcus granulosus	Jumonji AT rich interactive domain 1B	0.0011	0.0095	0.0041
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0011	0.0054	0.0054
Loa Loa (eye worm)	RNA binding protein	0.0066	0.3377	0.6627
Echinococcus granulosus	tar DNA binding protein	0.0066	0.3377	0.3341
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0011	0.0054	0.0104
Brugia malayi	PHD-finger family protein	0.0011	0.0102	0.0196
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0016	0.0408	0.0356
Echinococcus multilocularis	GPCR, family 2	0.0016	0.0408	0.0356
Brugia malayi	TAR-binding protein	0.0066	0.3377	0.6489
Echinococcus granulosus	cAMP specific 3'5' cyclic phosphodiesterase	0.0093	0.4993	0.4966
Schistosoma mansoni	hypothetical protein	0.0176	1	1
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0101	0.0094
Schistosoma mansoni	hypothetical protein	0.0016	0.0408	0.0408
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0011	0.0054	0.0104
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0016	0.0408	0.0705
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0011	0.0054	0.0104
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0011	0.0054	0.0104
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0016	0.0408	0.0783
Schistosoma mansoni	camp-specific 35-cyclic phosphodiesterase	0.0011	0.0101	0.0101
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0052	0.2535	0.4947
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0017	0.0445	0.0445
Loa Loa (eye worm)	jmjC domain-containing protein	0.0037	0.1662	0.3206
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0011	0.0054	0.0104
Echinococcus granulosus	jumonji domain containing protein	0.0041	0.1879	0.1835
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Echinococcus granulosus	calcium:calmodulin dependent 3'5' cyclic	0.0011	0.0101	0.0047
Echinococcus multilocularis	calcium:calmodulin dependent 3',5' cyclic	0.0011	0.0101	0.0047
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.002	0.0597	0.0546
Brugia malayi	jmjC domain containing protein	0.0096	0.5204	1
Brugia malayi	Bromodomain containing protein	0.0029	0.1188	0.2283
Schistosoma mansoni	calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase	0.0011	0.0101	0.0101
Echinococcus multilocularis	calcium:calmodulin dependent 3',5' cyclic	0.0011	0.0101	0.0047
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0094	0.5068	0.5042
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0094	0.5068	0.5068
Schistosoma mansoni	jumonji domain containing protein	0.0076	0.4016	0.4016
Brugia malayi	Steroid receptor seven-up type 2	0.0011	0.0054	0.0104
Plasmodium falciparum	phd finger protein, putative	0.0029	0.1188	1
Brugia malayi	Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative	0.0011	0.0101	0.0194
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.002	0.0597	0.5
Brugia malayi	Probable 3',5'-cyclic phosphodiesterase R153.1, putative	0.0011	0.0101	0.0194
Brugia malayi	Probable 3',5'-cyclic phosphodiesterase R153.1, putative	0.0081	0.4315	0.8292
Brugia malayi	ecdysteroid receptor	0.0011	0.0054	0.0104
Loa Loa (eye worm)	hypothetical protein	0.0093	0.4993	0.9849
Schistosoma mansoni	tar DNA-binding protein	0.0066	0.3377	0.3377
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Schistosoma mansoni	thyroid hormone receptor	0.0011	0.0054	0.0054
Echinococcus multilocularis	high affinity cAMP specific 3',5' cyclic	0.0011	0.0101	0.0047
Trypanosoma brucei	hypothetical protein, conserved	0.0011	0.0101	0.1693
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.002	0.0597	0.5
Brugia malayi	Latrophilin receptor protein 2	0.0016	0.0408	0.0783
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.002	0.0597	1
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0011	0.0054	0.0104
Trypanosoma brucei	3', 5'-cyclic nucleotide phosphodiesterase, putative	0.0011	0.0101	0.1693
Schistosoma mansoni	hypothetical protein	0.0016	0.0408	0.0408
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0011	0.0054	0.0104
Loa Loa (eye worm)	TAR-binding protein	0.0066	0.3377	0.6627
Echinococcus granulosus	PHD finger protein rhinoceros	0.0029	0.1188	0.114
Echinococcus multilocularis	cpg binding protein	0.0032	0.1318	0.1271
Toxoplasma gondii	PHD-finger domain-containing protein	0.0029	0.1188	0.238
Loa Loa (eye worm)	hypothetical protein	0.0035	0.155	0.2984
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0011	0.0054	0.0104
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Brugia malayi	PHD-finger family protein	0.0029	0.1188	0.2283
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0016	0.0408	0.0356
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0063	0.3225	0.3225
Echinococcus multilocularis	dual 3',5' cyclic AMP and GMP phosphodiesterase	0.0011	0.0101	0.0047
Plasmodium falciparum	conserved Plasmodium membrane protein, unknown function	0.0011	0.0109	0.0076
Brugia malayi	photoreceptor-specific nuclear receptor	0.0011	0.0054	0.0104
Schistosoma mansoni	tar DNA-binding protein	0.0066	0.3377	0.3377
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0094	0.5068	0.974
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0096	0.5204	0.5178
Schistosoma mansoni	tar DNA-binding protein	0.0066	0.3377	0.3377
Schistosoma mansoni	camp-specific 35-cyclic phosphodiesterase	0.0093	0.4993	0.4993
Brugia malayi	nuclear receptor NHR-88	0.0011	0.0054	0.0104
Schistosoma mansoni	retinoic acid receptor RXR	0.0011	0.0054	0.0054
Schistosoma mansoni	hypothetical protein	0.0176	1	1
Schistosoma mansoni	hypothetical protein	0.0029	0.1188	0.1188
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0011	0.0054	0.0054
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0011	0.0054	0.0054
Schistosoma mansoni	cpg binding protein	0.003	0.1216	0.1216
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0011	0.0054	0.0104
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0037	0.1662	0.1662
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.002	0.0597	0.4562
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.002	0.0597	0.1083
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Schistosoma mansoni	RAR-like nuclear receptor	0.0011	0.0054	0.0054
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0093	0.4993	1
Plasmodium vivax	hypothetical protein, conserved	0.0011	0.0109	0.0076
Schistosoma mansoni	nuclear hormone receptor	0.0011	0.0054	0.0054
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0066	0.3377	0.6627
Schistosoma mansoni	camp/cgmp cyclic nucleotide phosphodiesterase	0.0011	0.0101	0.0101
Trichomonas vaginalis	ap endonuclease, putative	0.002	0.0597	1
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0052	0.2535	0.4871
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0096	0.5204	0.5178
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0094	0.5068	0.5042
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Onchocerca volvulus		0.003	0.1216	1
Loa Loa (eye worm)	jmjC domain-containing protein	0.0061	0.3068	0.601
Schistosoma mansoni	ap endonuclease	0.002	0.0597	0.0597
Loa Loa (eye worm)	CXXC zinc finger family protein	0.003	0.1216	0.2317
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0057	0.2819	0.5647
Echinococcus multilocularis	peregrin	0.0029	0.1188	0.114
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0029	0.1188	0.1188
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.002	0.0597	1
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0011	0.0054	0.0054
Trypanosoma brucei	cAMP-specific phosphodiesterase, putative	0.0011	0.0101	0.1693
Schistosoma mansoni	camp-specific 35-cyclic phosphodiesterase	0.0011	0.0101	0.0101
Echinococcus multilocularis	jumonji domain containing protein	0.0041	0.1879	0.1835
Brugia malayi	Nuclear hormone receptor-like 1	0.0011	0.0054	0.0104
Brugia malayi	RNA recognition motif domain containing protein	0.0066	0.3377	0.6489
Brugia malayi	3'5'-cyclic nucleotide phosphodiesterase family protein	0.0011	0.0101	0.0194
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0102	0.0096
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0101	0.0094
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0094	0.5068	0.5042
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.002	0.0597	0.0546
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Schistosoma mansoni	ap endonuclease	0.002	0.0597	0.0597
Schistosoma mansoni	cpg binding protein	0.0032	0.1318	0.1318
Schistosoma mansoni	hypothetical protein	0.0016	0.0408	0.0408
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0011	0.0054	0.0054
Brugia malayi	exodeoxyribonuclease III family protein	0.002	0.0597	0.1147
Onchocerca volvulus	Alhambra homolog	0.0029	0.1188	0.9763
Brugia malayi	3'5'-cyclic nucleotide phosphodiesterase family protein	0.0011	0.0101	0.0194
Trypanosoma brucei	cAMP-specific phosphodiesterase	0.0011	0.0101	0.1693
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.002	0.0597	0.4562
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Schistosoma mansoni	thyroid hormone receptor	0.0011	0.0054	0.0054
Brugia malayi	steroid hormone receptor	0.0011	0.0054	0.0104
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Echinococcus multilocularis	lysine specific demethylase 5A	0.0036	0.156	0.1514
Brugia malayi	jmjC domain containing protein	0.0037	0.1662	0.3193
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0011	0.0054	0.0104
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.002	0.0597	0.1014
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.002	0.0597	1
Echinococcus multilocularis	high affinity cgmp specific 3' 5' cyclic	0.0011	0.0101	0.0047
Schistosoma mansoni	tar DNA-binding protein	0.0066	0.3377	0.3377
Toxoplasma gondii	exonuclease III APE	0.002	0.0597	0.1196
Loa Loa (eye worm)	PHD-finger family protein	0.0029	0.1188	0.2262
Trypanosoma brucei	cAMP phosphodiesterase A, putative	0.0011	0.0101	0.1693
Echinococcus multilocularis	tar DNA binding protein	0.0066	0.3377	0.3341
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0101	0.0094
Loa Loa (eye worm)	PDE1B protein	0.0011	0.0101	0.0094
Echinococcus multilocularis	cAMP and cAMP inhibited cGMP 3',5' cyclic	0.0011	0.0101	0.0047
Trichomonas vaginalis	ap endonuclease, putative	0.002	0.0597	1
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Loa Loa (eye worm)	hypothetical protein	0.005	0.2449	0.4776
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Brugia malayi	latrophilin 2 splice variant baaae	0.0035	0.155	0.2979
Echinococcus multilocularis	geminin	0.0176	1	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0094	0.5068	0.5068
Echinococcus granulosus	cAMP specific 3'5' cyclic phosphodiesterase	0.0093	0.4993	0.4966
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0037	0.1662	0.1662
Toxoplasma gondii	PHD-finger domain-containing protein	0.0029	0.1188	0.238
Treponema pallidum	exodeoxyribonuclease (exoA)	0.002	0.0597	0.5
Echinococcus multilocularis	cAMP specific 3',5' cyclic phosphodiesterase	0.0093	0.4993	0.4966
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0011	0.0054	0.0104
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0011	0.0054	0.0054
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0094	0.5068	0.5068
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.002	0.0597	1
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Trypanosoma brucei	3', 5'-cyclic nucleotide phosphodiesterase, putative	0.0011	0.0101	0.1693
Schistosoma mansoni	high-affinity cgmp-specific 35-cyclic phosphodiesterase	0.0011	0.0101	0.0101
Echinococcus multilocularis	Jumonji, AT rich interactive domain 1B	0.0011	0.0095	0.0041
Brugia malayi	CXXC zinc finger family protein	0.003	0.1216	0.2336
Loa Loa (eye worm)	hypothetical protein	0.0052	0.2535	0.4947
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0011	0.0054	0.0054
Echinococcus granulosus	GPCR family 2	0.0016	0.0408	0.0356
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0052	0.2535	0.4871
Echinococcus granulosus	cAMP and cAMP inhibited cGMP 3'5' cyclic	0.0011	0.0101	0.0047
Echinococcus granulosus	lysine specific demethylase 5A	0.0037	0.1662	0.1616
Brugia malayi	Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative	0.0011	0.0101	0.0194
Brugia malayi	3'5'-cyclic nucleotide phosphodiesterase family protein	0.0011	0.0101	0.0194
Echinococcus granulosus	cAMP specific 3'5' cyclic phosphodiesterase	0.0081	0.4315	0.4284
Loa Loa (eye worm)	cyclic AMP specific phosphodiesterase PDE4D5A	0.0081	0.4315	0.8497
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0094	0.5068	1
Echinococcus granulosus	peregrin	0.0029	0.1188	0.114
Schistosoma mansoni	high-affinity cgmp-specific 35-cyclic phosphodiesterase	0.0011	0.0101	0.0101
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0011	0.0101	0.0202
Giardia lamblia	PHD finger protein 15	0.0029	0.1188	0.2222
Schistosoma mansoni	hypothetical protein	0.0035	0.155	0.155
Brugia malayi	RNA binding protein	0.0066	0.3377	0.6489
Loa Loa (eye worm)	calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase	0.0011	0.0101	0.0094
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0011	0.0054	0.0104
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0094	0.5068	0.5042
Echinococcus granulosus	high affinity cgmp specific 3' 5' cyclic	0.0011	0.0101	0.0047
Brugia malayi	F/Y-rich N-terminus family protein	0.0019	0.0548	0.1052
Schistosoma mansoni	hypothetical protein	0.0016	0.0408	0.0408
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0029	0.1188	0.114
Echinococcus multilocularis	cAMP specific 3',5' cyclic phosphodiesterase	0.0093	0.4993	0.4966

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 610268