Detailed information for compound 610533

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 243.326 | Formula: C10H17N3O2S
  • H donors: 1 H acceptors: 2 LogP: 0.52 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: C/N=C\1/SC(C(=O)N1C)CC(=O)NC(C)C
  • InChi: 1S/C10H17N3O2S/c1-6(2)12-8(14)5-7-9(15)13(4)10(11-3)16-7/h6-7H,5H2,1-4H3,(H,12,14)/b11-10+
  • InChiKey: CCPTZSNXZOMMRF-ZHACJKMWSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0041
Giardia lamblia GTOR 0.0046 0.0543 0.4369
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0076 0.0076
Brugia malayi Pre-SET motif family protein 0.0213 0.3065 1
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0011 0.001 0.0031
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0543 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.128 0.128
Echinococcus granulosus GPCR family 2 0.0049 0.0578 0.0578
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0399 0.1113
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0011 0.001 0.0031
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0011 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0312 0.0863
Onchocerca volvulus 0.0098 0.1327 0.3783
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0092 0.123 0.123
Brugia malayi PHD-finger family protein 0.0011 0.0013 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0256 0.0704
Echinococcus granulosus intermediate filament protein 0.0027 0.0254 0.0254
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0578 0.1886
Echinococcus multilocularis lamin 0.0027 0.0254 0.0254
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0543 0.1771
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0296 0.082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0399 0.1113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0543 0.1524
Onchocerca volvulus Alhambra homolog 0.003 0.0288 0.082
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0137 0.5
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0031
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.128 0.4177
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0288 0.1043
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0011 0.001 0.0035
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.1306 0.1306
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0076 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.044 0.123
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0137 0.0365
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0254 0.083
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0092 0.123 0.446
Brugia malayi CXXC zinc finger family protein 0.003 0.0294 0.0959
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0081 0.1061 0.3462
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0011 0.001 0.001
Echinococcus multilocularis geminin 0.0177 0.2516 0.2516
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0193 0.2759 0.9
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0116 0.0421
Echinococcus granulosus lamin 0.0027 0.0254 0.0254
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0543 0.1968
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0011 0.0011
Brugia malayi Bromodomain containing protein 0.003 0.0288 0.0939
Brugia malayi PHD-finger family protein 0.003 0.0288 0.0939
Schistosoma mansoni tar DNA-binding protein 0.0193 0.2759 1
Brugia malayi jmjC domain containing protein 0.0037 0.0408 0.133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.022 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0076 0.019
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.123 1
Schistosoma mansoni ap endonuclease 0.002 0.0137 0.0498
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0011 0.001 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0363 0.1009
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0092 0.123 0.123
Brugia malayi intermediate filament protein 0.0027 0.0254 0.083
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0011 0.001 0.0031
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.2172 0.7085
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0076 0.0248
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0716 0.579
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0578 0.0578
Brugia malayi RNA binding protein 0.0193 0.2759 0.9
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0219 0.0599
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0011 0.0014 0.0169
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0543 0.0543
Schistosoma mansoni cpg binding protein 0.003 0.0294 0.1065
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0363 0.2894
Brugia malayi jmjC domain containing protein 0.0097 0.1306 0.426
Schistosoma mansoni lamin 0.0027 0.0254 0.0922
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0076 0.019
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0011 0.001 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.022 0.06
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0011 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0105 0.1434 0.5198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0219 0.0599
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0311 0.1129
Schistosoma mansoni hypothetical protein 0.0049 0.0578 0.2095
Schistosoma mansoni hypothetical protein 0.0049 0.0578 0.2095
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0011 0.001 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0363 0.1009
Echinococcus granulosus lamin dm0 0.0027 0.0254 0.0254
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0011 0.001 0.0035
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0076 0.0248
Loa Loa (eye worm) hypothetical protein 0.0098 0.1327 0.4331
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0311 0.0311
Echinococcus multilocularis cpg binding protein 0.0032 0.032 0.032
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0408 0.133
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0137 0.0448
Schistosoma mansoni hypothetical protein 0.0177 0.2516 0.9118
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0031
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0137 0.4232
Echinococcus multilocularis tumor protein p63 0.0671 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0363 0.1009
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0011 0.001 0.001
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0011 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0177 0.2516 0.9118
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0311 0.0311
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.04 0.7316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.022 0.06
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0011 0.001 0.0035
Plasmodium vivax hypothetical protein, conserved 0.003 0.0288 0.9217
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0137 0.4591
Schistosoma mansoni tar DNA-binding protein 0.0193 0.2759 1
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0092 0.123 0.123
Schistosoma mansoni ap endonuclease 0.002 0.0137 0.0498
Schistosoma mansoni tar DNA-binding protein 0.0193 0.2759 1
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0578 0.1886
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0076 0.1245
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.003 0.0288 0.0939
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.026 0.0716
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.2172 0.7085
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0076 0.0276
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.1434 0.4679
Echinococcus granulosus tar DNA binding protein 0.0193 0.2759 0.2759
Onchocerca volvulus 0.0027 0.0254 0.0725
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0578 0.0578
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0137 0.5
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0288 0.2279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0256 0.0704
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0011 0.001 0.001
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.04 0.7316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0363 0.1009
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0543 0.1771
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0578 0.0578
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0543 0.0543
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0011 0.0011
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0543 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0311 0.0311
Onchocerca volvulus 0.0031 0.0311 0.0888
Schistosoma mansoni cpg binding protein 0.0032 0.032 0.1159
Loa Loa (eye worm) hypothetical protein 0.0105 0.1434 0.4679
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0076 0.019
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.128 0.128
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.1306 0.1306
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0311 0.1129
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0543 1
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0463 0.0463
Trichomonas vaginalis set domain proteins, putative 0.0242 0.3509 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0254 0.083
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0311 0.2473
Loa Loa (eye worm) hypothetical protein 0.0027 0.0247 0.0805
Schistosoma mansoni hypothetical protein 0.0049 0.0578 0.2095
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0254 0.083
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0137 0.2395
Onchocerca volvulus 0.0027 0.0254 0.0725
Echinococcus multilocularis musashi 0.0027 0.0254 0.0254
Schistosoma mansoni intermediate filament proteins 0.0027 0.0254 0.0922
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0011 0.001 0.001
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0011 0.001 0.001
Brugia malayi RNA recognition motif domain containing protein 0.0193 0.2759 0.9
Loa Loa (eye worm) hypothetical protein 0.0092 0.123 0.4014
Schistosoma mansoni hypothetical protein 0.0049 0.0578 0.2095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0076 0.019
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.128 0.128
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.04 0.7316
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0543 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.004 0.004
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0014 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0219 0.0599
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0288 0.2279
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0137 0.5
Echinococcus multilocularis peregrin 0.003 0.0288 0.0288
Echinococcus granulosus peregrin 0.003 0.0288 0.0288
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0463 0.0463
Loa Loa (eye worm) TAR-binding protein 0.0193 0.2759 0.9
Toxoplasma gondii exonuclease III APE 0.002 0.0137 0.1046
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0011 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0363 0.1009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0543 0.1524
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0399 0.1113
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0311 0.1129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0399 0.1113
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0076 0.1245
Plasmodium falciparum phd finger protein, putative 0.003 0.0288 1
Schistosoma mansoni jumonji domain containing protein 0.0077 0.1005 0.3641
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0254 0.083
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0081 0.1061 0.1061
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0543 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0311 0.1016
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0076 0.1245
Onchocerca volvulus 0.0242 0.3509 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0819 0.2969
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0137 0.0448
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0543 1
Brugia malayi TAR-binding protein 0.0193 0.2759 0.9
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0011 0.001 0.0035
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0543 1
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0173 0.3057
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0137 0.0137
Giardia lamblia PHD finger protein 15 0.003 0.0288 0.2279
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0092 0.123 0.123
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0578 0.1886
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0011 0.001 0.0035
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0294 0.0959
Loa Loa (eye worm) PDE1B protein 0.0011 0.001 0.0031
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0062 0.0203
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0076 0.1245
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.2172 0.7085
Loa Loa (eye worm) hypothetical protein 0.0013 0.004 0.0131
Echinococcus multilocularis GPCR, family 2 0.0049 0.0578 0.0578
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.128 0.4641
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0408 0.1478
Echinococcus granulosus geminin 0.0177 0.2516 0.2516
Schistosoma mansoni cpg binding protein 0.0032 0.032 0.1159
Schistosoma mansoni tar DNA-binding protein 0.0193 0.2759 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0137 0.1046
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0288 0.0939
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0578 0.0578
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0543 1
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0408 0.0408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0029 0.0055
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0288 0.0288
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0011 0.001 0.0035
Brugia malayi Pre-SET motif family protein 0.0031 0.0311 0.1016
Loa Loa (eye worm) hypothetical protein 0.0051 0.0607 0.1982
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0132 0.2299
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0363 0.1009
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0288 0.0288
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0137 0.2395
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0011 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.026 0.0716
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.128 0.4177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.022 0.06
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0062 0.0203
Plasmodium vivax SET domain protein, putative 0.0031 0.0311 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.128 0.4641
Loa Loa (eye worm) hypothetical protein 0.0013 0.0033 0.0106
Echinococcus granulosus cpg binding protein 0.0032 0.032 0.032
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0092 0.123 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0033 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0363 0.1009
Schistosoma mansoni hypothetical protein 0.003 0.0288 0.1043
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0076 0.1245
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0081 0.1061 0.1061
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0011 0.001 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0543 0.1524
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0142 0.0464
Loa Loa (eye worm) hypothetical protein 0.0154 0.2172 0.7085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0399 0.1113
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0011 0.001 0.0031
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0137 0.2395
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0137 0.5
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.1327 0.4812
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0011 0.001 0.0035
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0011 0.001 0.0031
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0011 0.001 0.001
Schistosoma mansoni lamin 0.0027 0.0254 0.0922
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0011 0.001 0.0035
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0764 0.2493
Onchocerca volvulus 0.003 0.0294 0.0837
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0311 0.1129
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0137 0.0365
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0213 0.3065 1
Schistosoma mansoni tar DNA-binding protein 0.0193 0.2759 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0137 0.2395
Loa Loa (eye worm) RNA binding protein 0.0193 0.2759 0.9
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.026 0.0716
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.128 0.128
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0076 0.1245
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0408 0.1478
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0081 0.1061 0.3462
Loa Loa (eye worm) hypothetical protein 0.0049 0.0578 0.1886
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0285 0.0285
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0011 0.001 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.128 0.4641
Echinococcus multilocularis tar DNA binding protein 0.0193 0.2759 0.2759
Echinococcus multilocularis lamin dm0 0.0027 0.0254 0.0254

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.