TDR Targets

Basic information

Technical information

TDR Targets ID: 611662
Name: 3-(benzoylamino)-N-(4-chlorophenyl)-1-benzofu ran-2-carboxamide
MW: 390.819 | Formula: C22H15ClN2O3
H donors: 2 H acceptors: 2 LogP: 5.51 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: Clc1ccc(cc1)NC(=O)c1oc2c(c1NC(=O)c1ccccc1)cccc2
InChi: 1S/C22H15ClN2O3/c23-15-10-12-16(13-11-15)24-22(27)20-19(17-8-4-5-9-18(17)28-20)25-21(26)14-6-2-1-3-7-14/h1-13H,(H,24,27)(H,25,26)
InChiKey: PZIZCKLMLSDARY-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

3-(benzoylamino)-N-(4-chlorophenyl)benzofuran-2-carboxamide
N-(4-chlorophenyl)-3-[(oxo-phenylmethyl)amino]-2-benzofurancarboxamide
N-(4-chlorophenyl)-3-(phenylcarbonylamino)-1-benzofuran-2-carboxamide
ZINC04267805

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0038	0.1112	0.42
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0067	0.2321	0.2187
Plasmodium falciparum	glutathione reductase	0.005	0.1615	1
Echinococcus granulosus	beta LACTamase domain containing family member	0.0038	0.1112	0.1322
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0127	0.4855	0.4845
Echinococcus granulosus	histone lysine methyltransferase setb	0.0019	0.0296	0.009
Brugia malayi	beta-lactamase family protein	0.0038	0.1112	0.1074
Mycobacterium leprae	PROBABLE NADH DEHYDROGENASE NDH	0.0114	0.4318	0.874
Loa Loa (eye worm)	hypothetical protein	0.0038	0.1112	0.0841
Mycobacterium ulcerans	acyl-CoA synthetase	0.0026	0.0594	0.1715
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.002	0.0345	0.0616
Onchocerca volvulus	Huntingtin homolog	0.0126	0.4822	1
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0017	0.0237	0.0155
Entamoeba histolytica	acyl-coA synthetase, putative	0.0026	0.0594	1
Schistosoma mansoni	ap endonuclease	0.002	0.0345	0.0195
Echinococcus granulosus	thioredoxin glutathione reductase	0.005	0.1615	0.2082
Trypanosoma brucei	dihydrolipoyl dehydrogenase	0.0017	0.0237	0.0155
Brugia malayi	AMP-binding enzyme family protein	0.0026	0.0594	0.0554
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0066	0.2274	0.3077
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.002	0.0345	0.0927
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0096	0.3563	0.504
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0096	0.3563	0.5023
Leishmania major	acetoin dehydrogenase e3 component-like protein	0.0017	0.0237	0.0103
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.002	0.0345	1
Mycobacterium tuberculosis	Probable reductase	0.0114	0.4318	0.4282
Mycobacterium ulcerans	hypothetical protein	0.0038	0.1112	0.42
Loa Loa (eye worm)	hypothetical protein	0.0038	0.1112	0.0841
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0019	0.0319	0.0395
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0237	0.0155
Echinococcus granulosus	fetal alzheimer antigen falz	0.0025	0.0551	0.0475
Toxoplasma gondii	thioredoxin reductase	0.005	0.1615	0.6614
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.004	0.1172	0.1412
Echinococcus multilocularis	zinc finger protein	0.0022	0.0413	0.0267
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0026	0.0594	0.0375
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0319	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0126	0.4822	0.4664
Toxoplasma gondii	ABC1 family protein	0.0038	0.1112	0.42
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0237	0.0155
Trypanosoma brucei	trypanothione reductase	0.005	0.1615	1
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0244	0.977	1
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.002	0.0345	0.0927
Trypanosoma cruzi	trypanothione reductase, putative	0.0017	0.0237	0.0155
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.005	0.1615	0.1446
Mycobacterium tuberculosis	Probable hydrolase	0.0038	0.1112	0.0918
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.002	0.0345	0.0927
Loa Loa (eye worm)	glutathione reductase	0.005	0.1615	0.1359
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0114	0.4318	0.4282
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0127	0.4855	0.4845
Trichomonas vaginalis	esterase, putative	0.0038	0.1112	1
Brugia malayi	beta-lactamase	0.0038	0.1112	0.1074
Trichomonas vaginalis	ap endonuclease, putative	0.002	0.0345	0.1234
Echinococcus multilocularis	thioredoxin glutathione reductase	0.005	0.1615	0.2082
Schistosoma mansoni	methyl-cpg binding protein mbd	0.0019	0.0296	0.0122
Leishmania major	2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein	0.0017	0.0237	0.0103
Plasmodium falciparum	thioredoxin reductase	0.005	0.1615	1
Mycobacterium ulcerans	lipase LipD	0.0038	0.1112	0.42
Schistosoma mansoni	aldehyde dehydrogenase	0.0067	0.2321	0.317
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0594	0.0307
Schistosoma mansoni	acetyl-CoA C-acetyltransferase	0.0025	0.0551	0.0506
Schistosoma mansoni	aldehyde dehydrogenase	0.0067	0.2321	0.317
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0038	0.1112	0.135
Treponema pallidum	exodeoxyribonuclease (exoA)	0.002	0.0345	1
Leishmania major	hypothetical protein, conserved	0.0038	0.1112	0.4259
Trichomonas vaginalis	penicillin-binding protein, putative	0.0038	0.1112	1
Plasmodium falciparum	acyl-CoA synthetase	0.0019	0.0319	0.0597
Loa Loa (eye worm)	hypothetical protein	0.0045	0.1394	0.1132
Brugia malayi	beta-lactamase family protein	0.0038	0.1112	0.1074
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0319	0.0023
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0026	0.0594	0.1715
Onchocerca volvulus		0.0038	0.1112	0.2306
Mycobacterium tuberculosis	Conserved protein	0.0038	0.1112	0.0918
Leishmania major	4-coumarate:coa ligase-like protein	0.0026	0.0594	0.1801
Loa Loa (eye worm)	PHD-finger family protein	0.0023	0.0462	0.0171
Plasmodium vivax	acyl-CoA synthetase, putative	0.0019	0.0319	0.0597
Schistosoma mansoni	hypothetical protein	0.0023	0.0462	0.0372
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0018	0.0274	0.004
Leishmania major	4-coumarate:coa ligase-like protein	0.0026	0.0594	0.1801
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.002	0.0345	1
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.002	0.0345	0.0163
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0096	0.3563	0.5023
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0038	0.1112	0.1322
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0127	0.4855	1
Plasmodium vivax	glutathione reductase, putative	0.005	0.1615	1
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0017	0.0237	0.0155
Trichomonas vaginalis	penicillin-binding protein, putative	0.0038	0.1112	1
Mycobacterium tuberculosis	Probable oxidoreductase	0.0127	0.4855	0.4845
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0066	0.2274	0.3077
Schistosoma mansoni	hypothetical protein	0.0175	0.6859	1
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0067	0.2321	0.3148
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.004	0.1172	0.1412
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0038	0.1112	0.0841
Onchocerca volvulus		0.0038	0.1112	0.2306
Loa Loa (eye worm)	beta-lactamase	0.0038	0.1112	0.0841
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0067	0.2321	1
Brugia malayi	Bromodomain containing protein	0.0042	0.1281	0.1244
Mycobacterium leprae	conserved hypothetical protein	0.0038	0.1112	0.1215
Mycobacterium leprae	Probable lipase LipE	0.0038	0.1112	0.1215
Trichomonas vaginalis	D-aminoacylase, putative	0.0038	0.1112	1
Leishmania major	trypanothione reductase	0.005	0.1615	0.6649
Mycobacterium tuberculosis	Conserved protein	0.0038	0.1112	0.0918
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0594	0.0307
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0019	0.0296	0.009
Echinococcus granulosus	geminin	0.0175	0.6859	1
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0319	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0038	0.1112	0.0841
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.002	0.0345	0.0784
Echinococcus granulosus	methyl CpG binding domain protein 2	0.0019	0.0296	0.009
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0067	0.2321	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0018	0.0274	0.004
Mycobacterium tuberculosis	Probable dehydrogenase	0.0114	0.4318	0.4282
Loa Loa (eye worm)	bromodomain containing protein	0.0019	0.0325	0.0029
Echinococcus multilocularis	methyl CpG binding domain protein 2	0.0019	0.0296	0.009
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0019	0.0319	1
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.002	0.0345	0.0113
Loa Loa (eye worm)	hypothetical protein	0.0047	0.1483	0.1223
Loa Loa (eye worm)	hypothetical protein	0.0038	0.1112	0.0841
Mycobacterium tuberculosis	Probable lipase LipD	0.0038	0.1112	0.0918
Trypanosoma cruzi	trypanothione reductase, putative	0.005	0.1615	1
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0594	0.0307
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0026	0.0594	0.1715
Mycobacterium ulcerans	acyl-CoA synthetase	0.0026	0.0594	0.1715
Mycobacterium ulcerans	acyl-CoA synthetase	0.0026	0.0594	0.1715
Echinococcus granulosus	zinc finger protein	0.0022	0.0413	0.0267
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0096	0.3563	0.3535
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0038	0.1112	0.0918
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0017	0.0237	0.0155
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0067	0.2321	0.3148
Schistosoma mansoni	hypothetical protein	0.0175	0.6859	1
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0114	0.4318	0.4282
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0237	0.0155
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0067	0.2321	1
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0026	0.0594	0.1715
Loa Loa (eye worm)	hypothetical protein	0.0078	0.2785	0.2565
Onchocerca volvulus	Huntingtin homolog	0.0126	0.4822	1
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.002	0.0345	0.0784
Mycobacterium ulcerans	esterase/lipase LipP	0.0038	0.1112	0.42
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0018	0.0274	0.004
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.002	0.0345	0.0518
Toxoplasma gondii	exonuclease III APE	0.002	0.0345	0.0518
Schistosoma mansoni	dihydrolipoamide dehydrogenase	0.0017	0.0237	0.0033
Brugia malayi	Bromodomain containing protein	0.0083	0.2983	0.2953
Plasmodium vivax	hypothetical protein, conserved	0.0038	0.1112	0.6349
Mycobacterium tuberculosis	Probable lipase LipE	0.0038	0.1112	0.0918
Mycobacterium ulcerans	beta-lactamase	0.0038	0.1112	0.42
Brugia malayi	exodeoxyribonuclease III family protein	0.002	0.0345	0.0303
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0018	0.0274	0.004
Brugia malayi	hypothetical protein	0.0126	0.4822	0.48
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.002	0.0345	0.005
Brugia malayi	Thioredoxin reductase	0.005	0.1615	0.158
Trypanosoma brucei	dihydrolipoamide dehydrogenase, point mutation	0.0017	0.0237	0.0155
Brugia malayi	glutathione reductase	0.005	0.1615	0.158
Echinococcus multilocularis	geminin	0.0175	0.6859	1
Trichomonas vaginalis	D-aminoacylase, putative	0.0038	0.1112	1
Loa Loa (eye worm)	hypothetical protein	0.0038	0.1112	0.0841
Brugia malayi	dihydrolipoyl dehydrogenase, mitochondrial precursor, putative	0.0017	0.0237	0.0195
Echinococcus multilocularis	fetal alzheimer antigen, falz	0.0025	0.0551	0.0475
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0237	0.0155
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0096	0.3563	0.504
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0096	0.3563	0.3366
Schistosoma mansoni	ap endonuclease	0.002	0.0345	0.0195
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0096	0.3563	0.5023
Loa Loa (eye worm)	hypothetical protein	0.0126	0.4822	0.4664
Mycobacterium tuberculosis	Conserved protein	0.0038	0.1112	0.0918
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.002	0.0345	0.0163
Leishmania major	dihydrolipoamide dehydrogenase, putative	0.0017	0.0237	0.0103
Onchocerca volvulus		0.0038	0.1112	0.2306
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0017	0.0237	0.0155
Brugia malayi	PHD-finger family protein	0.0027	0.0661	0.0621
Leishmania major	4-coumarate:coa ligase-like protein	0.0026	0.0594	0.1801
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0249	1	1
Toxoplasma gondii	aldehyde dehydrogenase	0.0067	0.2321	1
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0114	0.4318	0.4282
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0026	0.0594	1
Mycobacterium ulcerans	hypothetical protein	0.0026	0.0594	0.1715
Plasmodium vivax	thioredoxin reductase, putative	0.005	0.1615	1
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0038	0.1112	0.0918
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0019	0.0296	0.0122
Trypanosoma cruzi	hypothetical protein, conserved	0.0038	0.1112	0.6406
Brugia malayi	AMP-binding enzyme family protein	0.0026	0.0594	0.0554
Trichomonas vaginalis	ap endonuclease, putative	0.002	0.0345	0.1234
Brugia malayi	AMP-binding enzyme family protein	0.0026	0.0594	0.0554
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0096	0.3563	0.5023
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0067	0.2321	1
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0319	0.0023
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0026	0.0594	0.1715
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0038	0.1112	0.1074
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0237	0.0155
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0114	0.4318	0.4282
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0026	0.0594	0.0375
Onchocerca volvulus		0.0026	0.0594	0.1232
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0026	0.0594	1
Loa Loa (eye worm)	thioredoxin reductase	0.005	0.1615	0.1359
Loa Loa (eye worm)	hypothetical protein	0.0038	0.1112	0.0841
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0237	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0042	0.1285	0.1019
Trypanosoma cruzi	hypothetical protein, conserved	0.0038	0.1112	0.6406
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0019	0.0319	0.0086
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0038	0.1112	0.0918
Schistosoma mansoni	zinc finger protein	0.0022	0.0413	0.0299
Leishmania major	dihydrolipoamide dehydrogenase, putative	0.0017	0.0237	0.0103
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0038	0.1112	0.135
Schistosoma mansoni	bromodomain containing protein	0.007	0.244	0.3349
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0319	0.0023
Mycobacterium tuberculosis	Probable esterase LipL	0.0038	0.1112	0.0918
Trichomonas vaginalis	D-aminoacylase, putative	0.0038	0.1112	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0096	0.3563	0.504
Schistosoma mansoni	methyl-cpg binding protein mbd	0.0019	0.0296	0.0122
Trypanosoma brucei	hypothetical protein, conserved	0.0038	0.1112	0.6406
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0019	0.0296	0.0122

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 611662