Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.2527 | 0.2527 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0024 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.2527 | 0.2527 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.5544 | 0.5544 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 1 | 1 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0024 | 1 | 1 |
Trichomonas vaginalis | chaperonin, putative | 0.0024 | 1 | 0.5 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 1 | 1 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0024 | 1 | 1 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.5544 | 0.5544 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.2527 | 0.2527 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.2527 | 0.2527 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.2527 | 0.2527 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.2527 | 0.2527 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0024 | 1 | 0.5 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.5544 | 0.5544 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.5544 | 0.5544 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.5544 | 0.5544 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0024 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.2527 | 0.2527 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.5544 | 0.5544 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0024 | 1 | 1 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0024 | 1 | 1 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0024 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.2527 | 0.2527 |
Onchocerca volvulus | 0.001 | 0.2527 | 0.5 | |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.2527 | 0.2527 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.5544 | 0.5544 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0024 | 1 | 1 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0024 | 1 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.2527 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.2527 | 0.2527 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.2527 | 0.2527 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.2527 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.2527 | 0.2527 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0024 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.2527 | 0.2527 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.5544 | 0.5544 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.2527 | 0.2527 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0015 | 0.5544 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.2527 | 0.2527 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.2527 | 0.2527 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.5544 | 0.5544 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.2527 | 0.2527 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.2527 | 0.2527 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.2527 | 0.2527 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.2527 | 0.5 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.5544 | 0.5544 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.2527 | 0.2527 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0024 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.2527 | 0.2527 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.