Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0421 | 0.3128 | 0.5017 |
Echinococcus multilocularis | geminin | 0.0173 | 0.1049 | 0.1473 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0474 | 0.0493 |
Entamoeba histolytica | hypothetical protein | 0.0086 | 0.0318 | 0.075 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0618 | 0.4777 | 0.4517 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0086 | 0.0318 | 0.075 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0104 | 0.0474 | 0.0493 |
Loa Loa (eye worm) | carboxylesterase | 0.0104 | 0.0474 | 0.0493 |
Loa Loa (eye worm) | DR-78 | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0421 | 0.3128 | 0.5017 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0199 | 0.1264 | 0.1839 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0421 | 0.3128 | 0.5017 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0199 | 0.1264 | 0.1839 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.0203 | 0.1299 | 0.19 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0554 | 0.4245 | 0.6921 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0421 | 0.3128 | 0.5017 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0199 | 0.1264 | 0.0829 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0421 | 0.3128 | 0.5017 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0108 | 0.0503 | 0.1185 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0421 | 0.3128 | 0.5017 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0199 | 0.1264 | 0.0829 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0421 | 0.3128 | 0.5017 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0554 | 0.4245 | 0.6921 |
Brugia malayi | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | ecdysteroid receptor | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.1463 | 0.2179 |
Giardia lamblia | Glycogen phosphorylase | 0.0554 | 0.4245 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0421 | 0.3128 | 0.5017 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0554 | 0.4245 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0421 | 0.3128 | 0.5017 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0554 | 0.4245 | 1 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.077 | 0.6052 | 0.5855 |
Brugia malayi | nuclear hormone receptor | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | Carboxylesterase family protein | 0.0618 | 0.4777 | 0.7826 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.1463 | 0.2179 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0222 | 0.1463 | 0.1039 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0618 | 0.4777 | 0.7826 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0618 | 0.4777 | 0.7826 |
Brugia malayi | nuclear receptor RXR | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0618 | 0.4777 | 0.7826 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0222 | 0.1463 | 0.2179 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0421 | 0.3128 | 0.5017 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0104 | 0.0474 | 0.0493 |
Brugia malayi | tailless protein | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative | 0.0095 | 0.0395 | 0.0359 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0421 | 0.3128 | 0.2786 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.3128 | 0.5017 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.1463 | 0.2179 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.077 | 0.6052 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0104 | 0.0474 | 0.0493 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0199 | 0.1264 | 0.1839 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.024 | 0.1608 | 0.3788 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | Carboxylesterase family protein | 0.0104 | 0.0474 | 0.0493 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0199 | 0.1264 | 0.1839 |
Echinococcus multilocularis | neuroligin | 0.0104 | 0.0474 | 0.0493 |
Brugia malayi | nuclear receptor NHR-67 | 0.0199 | 0.1264 | 0.1839 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0554 | 0.4245 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0199 | 0.1264 | 0.0829 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0554 | 0.4245 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0104 | 0.0474 | 0.0631 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.0105 | 0.0476 | 0.1122 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0474 | 0.0493 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0199 | 0.1264 | 0.1839 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.0108 | 0.0503 | 0.0703 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | hypothetical protein | 0.0222 | 0.1463 | 0.2179 |
Brugia malayi | carbohydrate phosphorylase | 0.0554 | 0.4245 | 0.6921 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0222 | 0.1463 | 0.2179 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.024 | 0.1608 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0421 | 0.3128 | 0.2786 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Echinococcus granulosus | glycogen phosphorylase | 0.0554 | 0.4245 | 0.6921 |
Onchocerca volvulus | 0.0199 | 0.1264 | 0.2094 | |
Schistosoma mansoni | zinc finger protein | 0.0199 | 0.1264 | 0.0829 |
Schistosoma mansoni | coup transcription factor | 0.0421 | 0.3128 | 0.2786 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0474 | 0.0493 |
Brugia malayi | Carboxylesterase family protein | 0.0618 | 0.4777 | 0.7826 |
Brugia malayi | nuclear receptor NHR-88 | 0.0421 | 0.3128 | 0.5017 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.3128 | 0.5017 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0108 | 0.0503 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0474 | 0.0493 |
Trypanosoma brucei | RNA helicase, putative | 0.0113 | 0.0543 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0618 | 0.4777 | 0.7826 |
Echinococcus granulosus | acetylcholinesterase | 0.0618 | 0.4777 | 0.7826 |
Echinococcus granulosus | carboxylesterase 5A | 0.0618 | 0.4777 | 0.7826 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.077 | 0.6052 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0108 | 0.0503 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.024 | 0.1608 | 0.3788 |
Schistosoma mansoni | glycogen phosphorylase | 0.0554 | 0.4245 | 0.3959 |
Schistosoma mansoni | nuclear hormone receptor | 0.0199 | 0.1264 | 0.0829 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0222 | 0.1463 | 0.1039 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0421 | 0.3128 | 0.5017 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.024 | 0.1608 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0421 | 0.3128 | 0.2786 |
Schistosoma mansoni | glycogen phosphorylase | 0.0554 | 0.4245 | 0.3959 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | carboxylesterase | 0.0104 | 0.0474 | 0.0493 |
Brugia malayi | nuclear receptor RXR | 0.0222 | 0.1463 | 0.2179 |
Brugia malayi | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0554 | 0.4245 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.1049 | 0.0603 |
Schistosoma mansoni | nuclear receptor | 0.0199 | 0.1264 | 0.0829 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0554 | 0.4245 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0474 | 0.0493 |
Echinococcus granulosus | FTZ F1 alpha | 0.0421 | 0.3128 | 0.5017 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0199 | 0.1264 | 0.2094 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0199 | 0.1264 | 0.0829 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0421 | 0.3128 | 0.5017 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0421 | 0.3128 | 0.5017 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0203 | 0.1299 | 0.0867 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.0543 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.1463 | 0.2179 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | Carboxylesterase family protein | 0.0104 | 0.0474 | 0.0493 |
Loa Loa (eye worm) | carboxylesterase | 0.0618 | 0.4777 | 0.7826 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.1049 | 0.0603 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0108 | 0.0503 | 0.0543 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0421 | 0.3128 | 0.5017 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0554 | 0.4245 | 0.6921 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0222 | 0.1463 | 0.2179 |
Echinococcus granulosus | glycogen phosphorylase | 0.0554 | 0.4245 | 0.6921 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0421 | 0.3128 | 0.5017 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0421 | 0.3128 | 0.5017 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0421 | 0.3128 | 0.2786 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0421 | 0.3128 | 0.5017 |
Schistosoma mansoni | thyroid hormone receptor | 0.0421 | 0.3128 | 0.2786 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0554 | 0.4245 | 0.6921 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | hypothetical protein | 0.0104 | 0.0474 | 0.0493 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0421 | 0.3128 | 0.7038 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0222 | 0.1463 | 0.2179 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0421 | 0.3128 | 0.2786 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0474 | 0.0493 |
Brugia malayi | nuclear receptor NHR-88 | 0.0199 | 0.1264 | 0.1839 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.077 | 0.6052 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0421 | 0.3128 | 0.2786 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0199 | 0.1264 | 0.1839 |
Onchocerca volvulus | 0.0199 | 0.1264 | 0.2094 | |
Brugia malayi | Nuclear hormone receptor E75 | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0474 | 0.0493 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0421 | 0.3128 | 0.5017 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0421 | 0.3128 | 0.5017 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0421 | 0.3128 | 0.7038 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.024 | 0.1608 | 0.3788 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0104 | 0.0474 | 0.0493 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0421 | 0.3128 | 0.2786 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.1463 | 0.2179 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0421 | 0.3128 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0421 | 0.3128 | 0.5017 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0104 | 0.0474 | 0.0631 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | steroid hormone receptor | 0.0421 | 0.3128 | 0.5017 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0199 | 0.1264 | 0.1839 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0421 | 0.3128 | 0.2786 |
Schistosoma mansoni | thyroid hormone receptor | 0.0421 | 0.3128 | 0.2786 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.077 | 0.6052 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0421 | 0.3128 | 0.5017 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.0203 | 0.1299 | 0.19 |
Echinococcus granulosus | geminin | 0.0173 | 0.1049 | 0.1473 |
Onchocerca volvulus | 0.0421 | 0.3128 | 0.7038 | |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0618 | 0.4777 | 0.7826 |
Brugia malayi | conserved hypotetical protein | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0421 | 0.3128 | 0.5017 |
Echinococcus granulosus | acetylcholinesterase | 0.0618 | 0.4777 | 0.7826 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0421 | 0.3128 | 0.7038 |
Schistosoma mansoni | nuclear receptor | 0.0199 | 0.1264 | 0.0829 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | Carboxylesterase family protein | 0.0104 | 0.0474 | 0.0493 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0421 | 0.3128 | 0.5017 |
Brugia malayi | nuclear hormone receptor | 0.0421 | 0.3128 | 0.5017 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0421 | 0.3128 | 0.2786 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.0108 | 0.0503 | 0.0703 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0104 | 0.0474 | 0.0493 |
Schistosoma mansoni | family A2 unassigned peptidase (A02 family) | 0.0226 | 0.149 | 0.1067 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0421 | 0.3128 | 0.5017 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0554 | 0.4245 | 0.6921 |
Schistosoma mansoni | glycogen phosphorylase | 0.024 | 0.1608 | 0.119 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0199 | 0.1264 | 0.1839 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0421 | 0.3128 | 0.5017 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0199 | 0.1264 | 0.1839 |
Echinococcus multilocularis | acetylcholinesterase | 0.0618 | 0.4777 | 0.7826 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0222 | 0.1463 | 0.2179 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0199 | 0.1264 | 0.2094 |
Brugia malayi | hypothetical protein | 0.0222 | 0.1463 | 0.2179 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0104 | 0.0474 | 0.0493 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0199 | 0.1264 | 0.1839 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0108 | 0.0503 | 0.0703 |
Brugia malayi | ecdysone receptor | 0.0199 | 0.1264 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1264 | 0.1839 |
Brugia malayi | Carboxylesterase family protein | 0.0104 | 0.0474 | 0.0493 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0421 | 0.3128 | 0.2786 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0181 | 0.1115 | 0.1585 |
Echinococcus granulosus | neuroligin | 0.0104 | 0.0474 | 0.0493 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (functional) | = 146 uM | Cytotoxic concentration of the compound in Wild Type CEM cells | ChEMBL. | 10229630 |
EC50 (functional) | 0 uM | Effect of compound against Moloney murine sarcoma virus (MSV)-induced transformation of C3H/3T3 embryo murine fibroblasts; Not determined | ChEMBL. | 10229630 |
EC50 (functional) | = 3.3 uM | Antiviral activity evaluated as the ability to inhibit the replication of HIV-2 in human T-lymphocytic cells (CEM) | ChEMBL. | 10229630 |
EC50 (functional) | = 3.67 uM | Antiviral activity evaluated as the ability to inhibit the replication of HIV-1 in human T-lymphocytic cells (CEM) | ChEMBL. | 10229630 |
logP (ADMET) | = 1.29 | Partition coefficient (logP) | ChEMBL. | 10229630 |
MCC (functional) | 0 uM | Minimal cytotoxic concentration required to cause morphological alteration of C3H/3T3 fibroblast culture cells; Not determined | ChEMBL. | 10229630 |
SI (functional) | = 44 | Selectivity index of the compound was determined by CC50 of CEM cells/EC50 of CEM cells against HIV-1 | ChEMBL. | 10229630 |
T1/2 (ADMET) | = 21.6 hr | Hydrolysis half life of the compound in phosphate buffer. | ChEMBL. | 10229630 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.