Detailed information for compound 615966

Basic information

Technical information
  • TDR Targets ID: 615966
  • Name: N-(4-iodophenyl)piperidine-1-sulfonamide
  • MW: 366.218 | Formula: C11H15IN2O2S
  • H donors: 1 H acceptors: 2 LogP: 2.29 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Ic1ccc(cc1)NS(=O)(=O)N1CCCCC1
  • InChi: 1S/C11H15IN2O2S/c12-10-4-6-11(7-5-10)13-17(15,16)14-8-2-1-3-9-14/h4-7,13H,1-3,8-9H2
  • InChiKey: DTXVVGGBTQYGDS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-iodophenyl)-1-piperidinesulfonamide
  • ZINC02697151

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0018 0.0015
Echinococcus multilocularis lamin dm0 0.0027 0.0091 0.0088
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0337 0.2006 0.5695
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0337 0.2006 0.8229
Brugia malayi nuclear receptor NHR-88 0.0337 0.2006 0.4094
Onchocerca volvulus 0.0037 0.0152 0.0128
Loa Loa (eye worm) hypothetical protein 0.0337 0.2006 0.4109
Echinococcus granulosus survival motor neuron protein 1 0.024 0.1407 0.399
Echinococcus granulosus geminin 0.0168 0.0963 0.2729
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0152 0.097
Loa Loa (eye worm) hypothetical protein 0.0037 0.0152 0.0311
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0018 0.0015
Schistosoma mansoni cpg binding protein 0.0058 0.0278 0.1106
Schistosoma mansoni hypothetical protein 0.0049 0.0224 0.0883
Schistosoma mansoni hypothetical protein 0.0016 0.0019 0.0038
Brugia malayi conserved hypotetical protein 0.0148 0.0834 0.1687
Schistosoma mansoni nuclear hormone receptor 0.0148 0.0834 0.3396
Schistosoma mansoni nuclear receptor nhr-48 0.0148 0.0834 0.3396
Echinococcus granulosus dnaJ subfamily B 0.0407 0.2436 0.6916
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.019 0.1094 0.224
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0152 0.0287
Schistosoma mansoni hypothetical protein 0.0034 0.0133 0.0506
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0148 0.0834 0.0831
Loa Loa (eye worm) hypothetical protein 0.019 0.1094 0.224
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0018 0.0035
Brugia malayi nuclear receptor NHR-88 0.0148 0.0834 0.1687
Mycobacterium ulcerans beta-lactamase 0.0037 0.0152 0.5
Brugia malayi Nuclear hormone receptor E75 0.0148 0.0834 0.1687
Mycobacterium tuberculosis Conserved protein 0.0037 0.0152 0.097
Brugia malayi hypothetical protein 0.015 0.085 0.1721
Brugia malayi orphan nuclear receptor NR2E1 0.0148 0.0834 0.1687
Loa Loa (eye worm) RNA binding protein 0.0064 0.0314 0.0644
Brugia malayi photoreceptor-specific nuclear receptor 0.0337 0.2006 0.4094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0337 0.2006 0.4109
Loa Loa (eye worm) hypothetical protein 0.024 0.1407 0.2881
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0019 0.0046
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0148 0.0834 0.1551
Onchocerca volvulus 0.0037 0.0152 0.0128
Onchocerca volvulus Bile acid receptor homolog 0.0802 0.4883 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0337 0.2006 0.3997
Toxoplasma gondii ABC1 family protein 0.0037 0.0152 0.2303
Brugia malayi hypothetical protein 0.019 0.1094 0.222
Schistosoma mansoni thyroid hormone receptor 0.0337 0.2006 0.8229
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0152 1
Echinococcus multilocularis survival motor neuron protein 1 0.024 0.1407 0.1404
Brugia malayi beta-lactamase family protein 0.0037 0.0152 0.0287
Echinococcus multilocularis nuclear receptor nhr 48 0.0148 0.0834 0.0831
Loa Loa (eye worm) hypothetical protein 0.005 0.0231 0.0472
Echinococcus multilocularis FTZ F1 alpha 0.0337 0.2006 0.2004
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0337 0.2006 0.8229
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0152 0.0149
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0032 0.0082
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Echinococcus multilocularis musashi 0.0027 0.0091 0.0088
Mycobacterium leprae Probable lipase LipE 0.0037 0.0152 0.5
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0337 0.2006 0.4094
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0152 0.097
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0337 0.2006 0.4094
Loa Loa (eye worm) hypothetical protein 0.0337 0.2006 0.4109
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.001 0.0007
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0019 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0337 0.2006 0.4094
Schistosoma mansoni nuclear receptor 0.0148 0.0834 0.3396
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0203 0.0567
Schistosoma mansoni retinoic acid receptor RXR 0.0337 0.2006 0.8229
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.001 0.002
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.019 0.1094 0.4467
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0337 0.2006 0.2004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0018 0.0015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0152 0.0585
Onchocerca volvulus 0.015 0.085 0.1585
Brugia malayi nuclear receptor NHR-67 0.0148 0.0834 0.1687
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0152 1
Brugia malayi nuclear hormone receptor 0.0148 0.0834 0.1687
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0337 0.2006 0.4094
Mycobacterium ulcerans lipase LipD 0.0037 0.0152 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0152 1
Brugia malayi tailless protein 0.0148 0.0834 0.1687
Echinococcus granulosus Nuclear hormone receptor HR96 0.0148 0.0834 0.2362
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0203 0.0794
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0032 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0337 0.2006 0.4109
Onchocerca volvulus 0.0058 0.0278 0.0391
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0148 0.0834 0.3396
Brugia malayi beta-lactamase 0.0037 0.0152 0.0287
Echinococcus granulosus nuclear receptor nhr 48 0.0148 0.0834 0.2362
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0337 0.2006 0.4109
Mycobacterium tuberculosis Conserved protein 0.0037 0.0152 0.097
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0148 0.0834 0.2362
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0152 0.097
Schistosoma mansoni coup transcription factor 0.0337 0.2006 0.8229
Loa Loa (eye worm) nuclear receptor NHR-67 0.0148 0.0834 0.1708
Schistosoma mansoni zinc finger protein 0.0148 0.0834 0.3396
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0337 0.2006 0.5695
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0152 1
Brugia malayi Nuclear hormone receptor-like 1 0.019 0.1094 0.222
Trichomonas vaginalis esterase, putative 0.0037 0.0152 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0337 0.2006 0.2004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0203 0.0415
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Loa Loa (eye worm) hypothetical protein 0.0037 0.0152 0.0311
Schistosoma mansoni survival motor neuron protein 0.0049 0.0224 0.0883
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0224 0.0436
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0337 0.2006 0.8229
Echinococcus granulosus intermediate filament protein 0.0027 0.0091 0.0249
Echinococcus granulosus lamin 0.0027 0.0091 0.0249
Schistosoma mansoni lamin 0.0027 0.0091 0.0333
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0314 0.0644
Schistosoma mansoni intermediate filament proteins 0.0027 0.0091 0.0333
Onchocerca volvulus 0.0337 0.2006 0.3997
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Brugia malayi hypothetical protein 0.0148 0.0834 0.1687
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0152 0.5
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0337 0.2006 0.8229
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0203 0.0794
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0337 0.2006 0.4109
Brugia malayi MH2 domain containing protein 0.0119 0.0655 0.1321
Loa Loa (eye worm) hypothetical protein 0.0337 0.2006 0.4109
Loa Loa (eye worm) steroid hormone receptor 0.0771 0.4693 0.9611
Mycobacterium tuberculosis Conserved protein 0.0037 0.0152 0.097
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0337 0.2006 0.4109
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0337 0.2006 0.4094
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0018 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0152 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0148 0.0834 0.1687
Loa Loa (eye worm) hypothetical protein 0.0337 0.2006 0.4109
Schistosoma mansoni hypothetical protein 0.0016 0.0019 0.0038
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0314 0.1255
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0337 0.2006 0.8229
Echinococcus multilocularis GPCR, family 2 0.0016 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.019 0.1094 0.224
Loa Loa (eye worm) hypothetical protein 0.0037 0.0152 0.0311
Brugia malayi steroid hormone receptor 0.0771 0.4693 0.961
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0152 1
Loa Loa (eye worm) hypothetical protein 0.019 0.1094 0.224
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0091 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0337 0.2006 0.4094
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0337 0.2006 0.5695
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0091 0.0186
Echinococcus multilocularis geminin 0.0168 0.0963 0.096
Echinococcus granulosus lamin dm0 0.0027 0.0091 0.0249
Schistosoma mansoni steroid hormone receptor ad4bp 0.0337 0.2006 0.8229
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0148 0.0834 0.0831
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0337 0.2006 0.5695
Echinococcus granulosus GPCR family 2 0.0016 0.0019 0.0046
Loa Loa (eye worm) hypothetical protein 0.0027 0.0088 0.0179
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0039
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0314 0.1255
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0314 0.1255
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0337 0.2006 0.4094
Brugia malayi RNA binding protein 0.0064 0.0314 0.0621
Brugia malayi hypothetical protein 0.024 0.1407 0.2863
Schistosoma mansoni nuclear hormone receptor 0.0148 0.0834 0.3396
Brugia malayi hypothetical protein 0.019 0.1094 0.222
Loa Loa (eye worm) hypothetical protein 0.015 0.085 0.1741
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0148 0.0834 0.3396
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0133 0.0248
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0203 0.0567
Loa Loa (eye worm) hypothetical protein 0.0337 0.2006 0.4109
Loa Loa (eye worm) beta-lactamase 0.0037 0.0152 0.0311
Brugia malayi nuclear receptor RXR 0.0148 0.0834 0.1687
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0152 0.097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0337 0.2006 0.4109
Schistosoma mansoni retinoid-x-receptor (RXR) 0.019 0.1094 0.4467
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0019 0.0015
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0152 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0018 0.5
Toxoplasma gondii histone lysine methyltransferase SET1 0.0109 0.0598 1
Brugia malayi hypothetical protein 0.0148 0.0834 0.1687
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0337 0.2006 0.5695
Echinococcus granulosus ecdysone induced protein 78C 0.0337 0.2006 0.5695
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.003 0.0038
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.2436 0.2434
Brugia malayi Nuclear hormone receptor-like 1 0.0337 0.2006 0.4094
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0314 0.0621
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0152 0.0585
Schistosoma mansoni hypothetical protein 0.0016 0.0019 0.0038
Loa Loa (eye worm) hypothetical protein 0.019 0.1094 0.224
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0152 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0148 0.0834 0.0831
Loa Loa (eye worm) DR-78 0.0148 0.0834 0.1708
Schistosoma mansoni hypothetical protein 0.0168 0.0963 0.3929
Schistosoma mansoni RAR-like nuclear receptor 0.0337 0.2006 0.8229
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0278 0.057
Echinococcus granulosus FTZ F1 alpha 0.0337 0.2006 0.5695
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0152 0.097
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0152 0.5
Loa Loa (eye worm) nuclear hormone receptor 0.0148 0.0834 0.1708
Schistosoma mansoni thyroid hormone receptor 0.0337 0.2006 0.8229
Brugia malayi intermediate filament protein 0.0027 0.0091 0.0161
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0314 0.0644
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0337 0.2006 0.2004
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0019 0.0016
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0152 0.5
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0337 0.2006 0.4094
Schistosoma mansoni hypothetical protein 0.0407 0.2436 1
Brugia malayi nuclear hormone receptor 0.0337 0.2006 0.4094
Brugia malayi CXXC zinc finger family protein 0.0058 0.0278 0.0547
Loa Loa (eye worm) hypothetical protein 0.0037 0.0152 0.0311
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.019 0.1094 0.31
Brugia malayi Nuclear hormone receptor E75 0.0148 0.0834 0.1687
Echinococcus granulosus Nuclear hormone receptor HR96 0.0148 0.0834 0.2362
Brugia malayi TAR-binding protein 0.0064 0.0314 0.0621
Loa Loa (eye worm) hypothetical protein 0.0337 0.2006 0.4109
Loa Loa (eye worm) hypothetical protein 0.0027 0.0091 0.0186
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0152 0.097
Brugia malayi Steroid receptor seven-up type 2 0.0337 0.2006 0.4094
Echinococcus multilocularis lamin 0.0027 0.0091 0.0088
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0231 0.0449
Echinococcus granulosus cpg binding protein 0.0061 0.0299 0.084
Brugia malayi ecdysone receptor 0.0148 0.0834 0.1687
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0337 0.2006 0.4094
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0337 0.2006 0.4094
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0018 0.0015
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0091 0.0186
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.001 0.002
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0314 0.1255
Onchocerca volvulus 0.0037 0.0152 0.0128
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0152 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0019 0.0039
Schistosoma mansoni nuclear receptor 0.0148 0.0834 0.3396
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0337 0.2006 0.8229
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0148 0.0834 0.2362
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0148 0.0834 0.1551
Schistosoma mansoni nuclear hormone receptor 0.0337 0.2006 0.8229
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0203 0.02
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0018 0.0044
Brugia malayi ecdysteroid receptor 0.0802 0.4883 1
Mycobacterium ulcerans hypothetical protein 0.0037 0.0152 0.5
Loa Loa (eye worm) hypothetical protein 0.0034 0.0133 0.0272
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0152 0.0423
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0152 0.0311
Echinococcus multilocularis ecdysone induced protein 78C 0.0337 0.2006 0.2004
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Schistosoma mansoni hypothetical protein 0.0016 0.0019 0.0038
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0231 0.0472
Onchocerca volvulus 0.0148 0.0834 0.1551
Loa Loa (eye worm) hypothetical protein 0.0037 0.0152 0.0311
Brugia malayi isocitrate dehydrogenase 0.0016 0.0018 0.0013
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0148 0.0834 0.0831
Onchocerca volvulus 0.0049 0.0224 0.0279
Loa Loa (eye worm) hypothetical protein 0.0337 0.2006 0.4109
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0203 0.0794
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0337 0.2006 0.5695
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0203 0.02
Brugia malayi nuclear hormone receptor family member nhr-6 0.0148 0.0834 0.1687
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0337 0.2006 0.4094
Echinococcus granulosus thyroid hormone receptor alpha 0.0582 0.3521 1
Leishmania major hypothetical protein, conserved 0.0037 0.0152 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.0678 0.2755
Brugia malayi beta-lactamase family protein 0.0037 0.0152 0.0287
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0337 0.2006 0.4094
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0337 0.2006 0.2004
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0337 0.2006 0.2004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0203 0.0391
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0337 0.2006 0.2004
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0655 0.1342
Schistosoma mansoni lamin 0.0027 0.0091 0.0333
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0655 0.1342
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0148 0.0834 0.1708
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.019 0.1094 0.1091
Schistosoma mansoni hypothetical protein 0.0168 0.0963 0.3929
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0018 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.019 0.1094 0.222
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0337 0.2006 0.4094
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0032 0.0029
Brugia malayi nuclear receptor RXR 0.019 0.1094 0.222
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Brugia malayi nuclear hormone receptor family member odr-7 0.0148 0.0834 0.1687
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0337 0.2006 0.2004
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0152 0.0311
Onchocerca volvulus 0.0148 0.0834 0.1551
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0152 0.097
Loa Loa (eye worm) hypothetical protein 0.0148 0.0834 0.1708
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0337 0.2006 0.5695
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0337 0.2006 0.4109
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0019 0.0046
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0238 0.1394 1
Loa Loa (eye worm) hypothetical protein 0.019 0.1094 0.224
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0148 0.0834 0.0831
Echinococcus granulosus tar DNA binding protein 0.0064 0.0314 0.0885
Loa Loa (eye worm) hypothetical protein 0.0802 0.4883 1
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0314 0.1255
Onchocerca volvulus Protein ultraspiracle homolog 0.0337 0.2006 0.3997
Schistosoma mansoni cpg binding protein 0.0061 0.0299 0.119
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0231 0.0449
Echinococcus multilocularis cpg binding protein 0.0061 0.0299 0.0296
Schistosoma mansoni cpg binding protein 0.0061 0.0299 0.119
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0018 0.0013
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0314 0.0311

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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