Detailed information for compound 615968

Basic information

Technical information
  • TDR Targets ID: 615968
  • Name: 1-[5-furan-2-yl-3-(2-methoxyphenyl)-4,5-dihyd ropyrazol-1-yl]ethanone
  • MW: 284.31 | Formula: C16H16N2O3
  • H donors: 0 H acceptors: 1 LogP: 1.77 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1C1=NN(C(C1)c1ccco1)C(=O)C
  • InChi: 1S/C16H16N2O3/c1-11(19)18-14(16-8-5-9-21-16)10-13(17-18)12-6-3-4-7-15(12)20-2/h3-9,14H,10H2,1-2H3
  • InChiKey: SHDSYTNRROFRLT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-[5-(2-furyl)-3-(2-methoxyphenyl)-4,5-dihydropyrazol-1-yl]ethanone
  • BAS 03296449
  • 1-[5-Furan-2-yl-3-(2-methoxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0196 0.3744 0.3744
Loa Loa (eye worm) cysteine protease 0.0017 0.002 0.002
Brugia malayi nuclear receptor NHR-67 0.0085 0.1441 0.1441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Brugia malayi nuclear hormone receptor 0.0085 0.1441 0.1441
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0196 0.3744 0.4454
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Brugia malayi nuclear hormone receptor 0.0196 0.3744 0.3744
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0196 0.3744 0.4454
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.002 0.5
Loa Loa (eye worm) hypothetical protein 0.0196 0.3744 0.3744
Echinococcus multilocularis cysteine protease 0.0017 0.002 0.0024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0085 0.1441 0.1714
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0196 0.3744 0.3744
Loa Loa (eye worm) hypothetical protein 0.0111 0.1979 0.1979
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0085 0.1441 0.1714
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0196 0.3744 0.3744
Schistosoma mansoni nuclear receptor 0.0085 0.1441 0.1714
Loa Loa (eye worm) hypothetical protein 0.0111 0.1979 0.1979
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0085 0.1441 0.1714
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0196 0.3744 0.3744
Schistosoma mansoni nuclear receptor nhr-48 0.0085 0.1441 0.1714
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.002 0.5
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0111 0.1979 0.2354
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0196 0.3744 0.4454
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0196 0.3744 0.4454
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0196 0.3744 0.4454
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.002 0.5
Echinococcus multilocularis thyroid hormone receptor alpha 0.0196 0.3744 0.4454
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.002 0.5
Schistosoma mansoni coup transcription factor 0.0196 0.3744 0.4454
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0196 0.3744 0.3744
Brugia malayi nuclear hormone receptor family member nhr-6 0.0085 0.1441 0.1441
Brugia malayi conserved hypotetical protein 0.0085 0.1441 0.1441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0196 0.3744 0.3744
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0196 0.3744 0.3744
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0988 1
Echinococcus granulosus nuclear receptor nhr 48 0.0085 0.1441 0.1714
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0085 0.1441 0.1714
Schistosoma mansoni nuclear receptor 0.0085 0.1441 0.1714
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0196 0.3744 0.4454
Schistosoma mansoni RAR-like nuclear receptor 0.0196 0.3744 0.4454
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0701 0.0701
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0196 0.3744 0.4454
Brugia malayi Cathepsin L-like precursor 0.0017 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0196 0.3744 0.3744
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0196 0.3744 0.3744
Loa Loa (eye worm) fibroinase 0.0017 0.002 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Leishmania major cathepsin L-like protease 0.0063 0.0988 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.002 0.5
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0421 0.8406 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.002 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0196 0.3744 0.4454
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0196 0.3744 0.3744
Brugia malayi steroid hormone receptor 0.0478 0.9587 0.9587
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0085 0.1441 0.1714
Brugia malayi photoreceptor-specific nuclear receptor 0.0196 0.3744 0.3744
Schistosoma mansoni steroid hormone receptor ad4bp 0.0196 0.3744 0.4454
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0421 0.8406 0.8406
Echinococcus granulosus Nuclear hormone receptor HR96 0.0085 0.1441 0.1714
Loa Loa (eye worm) hypothetical protein 0.0111 0.1979 0.1979
Brugia malayi Nuclear hormone receptor-like 1 0.0196 0.3744 0.3744
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0196 0.3744 0.4454
Schistosoma mansoni nuclear hormone receptor 0.0196 0.3744 0.4454
Brugia malayi Nuclear hormone receptor E75 0.0085 0.1441 0.1441
Loa Loa (eye worm) hypothetical protein 0.0196 0.3744 0.3744
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0874 0.8824
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.002 0.5
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0196 0.3744 0.4454
Brugia malayi nuclear hormone receptor family member odr-7 0.0085 0.1441 0.1441
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0196 0.3744 0.3744
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0988 1
Loa Loa (eye worm) hypothetical protein 0.0196 0.3744 0.3744
Loa Loa (eye worm) nuclear receptor NHR-67 0.0085 0.1441 0.1441
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.002 0.0024
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.2132 0.2132
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0196 0.3744 0.3744
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0377 0.0377
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0111 0.1979 0.2354
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0701 0.0701
Brugia malayi orphan nuclear receptor NR2E1 0.0085 0.1441 0.1441
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0196 0.3744 0.3744
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0085 0.1441 0.1423
Brugia malayi Cathepsin L-like precursor 0.0017 0.002 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.002 0.5
Brugia malayi Nuclear hormone receptor-like 1 0.0111 0.1979 0.1979
Echinococcus multilocularis ecdysone induced protein 78C 0.0196 0.3744 0.4454
Echinococcus granulosus Nuclear hormone receptor HR96 0.0085 0.1441 0.1714
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0196 0.3744 0.3744
Brugia malayi Cathepsin L-like precursor 0.0017 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0085 0.1441 0.1714
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0196 0.3744 0.4454
Loa Loa (eye worm) nuclear hormone receptor 0.0085 0.1441 0.1441
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0111 0.1979 0.1979
Brugia malayi ecdysone receptor 0.0085 0.1441 0.1441
Brugia malayi nuclear receptor RXR 0.0111 0.1979 0.1979
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.002
Brugia malayi hypothetical protein 0.0085 0.1441 0.1441
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.002 0.5
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0421 0.8406 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.002 0.002
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.002 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.002 0.5
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.002 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Loa Loa (eye worm) DR-78 0.0085 0.1441 0.1441
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0196 0.3744 0.3744
Leishmania major cathepsin L-like protease 0.0063 0.0988 1
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.2132 0.2132
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0085 0.1441 0.1441
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0196 0.3744 0.4454
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0196 0.3744 0.4454
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.002 0.002
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0988 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Plasmodium vivax vivapain-2 0.0017 0.002 0.5
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Echinococcus granulosus ecdysone induced protein 78C 0.0196 0.3744 0.4454
Echinococcus multilocularis FTZ F1 alpha 0.0196 0.3744 0.4454
Loa Loa (eye worm) hypothetical protein 0.0111 0.1979 0.1979
Echinococcus granulosus cathepsin l1 0.0017 0.002 0.0024
Schistosoma mansoni retinoic acid receptor RXR 0.0196 0.3744 0.4454
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Entamoeba histolytica cysteine protease, putative 0.0017 0.002 0.5
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0701 0.0701
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.002 0.0024
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Loa Loa (eye worm) hypothetical protein 0.0034 0.0377 0.0377
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0421 0.8406 0.8406
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0196 0.3744 0.3744
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0196 0.3744 0.3744
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.002 0.0024
Brugia malayi Cathepsin L-like precursor 0.0017 0.002 0.002
Toxoplasma gondii cathepsin CPL 0.0017 0.002 0.5
Echinococcus granulosus thyroid hormone receptor alpha 0.0367 0.7283 0.8664
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0085 0.1441 0.1714
Loa Loa (eye worm) ctsf protein 0.0017 0.002 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0196 0.3744 0.3744
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0196 0.3744 0.3744
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0196 0.3744 0.3744
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Onchocerca volvulus 0.0085 0.1441 0.1423
Brugia malayi Steroid receptor seven-up type 2 0.0196 0.3744 0.3744
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0111 0.1979 0.2354
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Brugia malayi MH2 domain containing protein 0.0118 0.2132 0.2132
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.002 0.5
Schistosoma mansoni nuclear hormone receptor 0.0085 0.1441 0.1714
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.002 0.0024
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0196 0.3744 0.4454
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0196 0.3744 0.4454
Onchocerca volvulus Protein ultraspiracle homolog 0.0196 0.3744 0.3732
Echinococcus multilocularis cysteine protease 0.0017 0.002 0.0024
Onchocerca volvulus 0.0085 0.1441 0.1423
Leishmania major cathepsin L-like protease 0.0063 0.0988 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0196 0.3744 0.3744
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Brugia malayi Nuclear hormone receptor E75 0.0085 0.1441 0.1441
Plasmodium vivax vivapain-2 0.0017 0.002 0.5
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.002 0.5
Brugia malayi nuclear receptor NHR-88 0.0085 0.1441 0.1441
Brugia malayi hypothetical protein 0.0085 0.1441 0.1441
Brugia malayi Nuclear hormone receptor-like 1 0.0111 0.1979 0.1979
Schistosoma mansoni hypothetical protein 0.0034 0.0377 0.0448
Schistosoma mansoni thyroid hormone receptor 0.0196 0.3744 0.4454
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.002 0.5
Brugia malayi hypothetical protein 0.0111 0.1979 0.1979
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0085 0.1441 0.1423
Onchocerca volvulus Bile acid receptor homolog 0.0498 1 1
Echinococcus granulosus FTZ F1 alpha 0.0196 0.3744 0.4454
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0196 0.3744 0.4454
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0196 0.3744 0.4454
Brugia malayi Cathepsin L-like precursor 0.0017 0.002 0.002
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0988 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0196 0.3744 0.4454
Schistosoma mansoni thyroid hormone receptor 0.0196 0.3744 0.4454
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.002 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.002 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.002 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0085 0.1441 0.1714
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Onchocerca volvulus 0.0196 0.3744 0.3732
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0707 0.7098
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.002 0.002
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0085 0.1441 0.1441
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0196 0.3744 0.4454
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.002 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0085 0.1441 0.1714
Brugia malayi tailless protein 0.0085 0.1441 0.1441
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0196 0.3744 0.3732
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.002 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Schistosoma mansoni zinc finger protein 0.0085 0.1441 0.1714
Brugia malayi hypothetical protein 0.0111 0.1979 0.1979
Brugia malayi nuclear receptor NHR-88 0.0196 0.3744 0.3744
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0988 0.5
Loa Loa (eye worm) hypothetical protein 0.0196 0.3744 0.3744
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0111 0.1979 0.2354
Loa Loa (eye worm) hypothetical protein 0.0196 0.3744 0.3744
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0421 0.8406 1
Loa Loa (eye worm) hypothetical protein 0.0196 0.3744 0.3744
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441
Loa Loa (eye worm) steroid hormone receptor 0.0478 0.9587 0.9587
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Loa Loa (eye worm) hypothetical protein 0.0111 0.1979 0.1979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.002 0.5
Schistosoma mansoni nuclear hormone receptor 0.0085 0.1441 0.1714
Brugia malayi nuclear receptor RXR 0.0085 0.1441 0.1441
Loa Loa (eye worm) hypothetical protein 0.0498 1 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0701 0.0701
Echinococcus multilocularis nuclear receptor nhr 48 0.0085 0.1441 0.1714
Brugia malayi Cathepsin L-like precursor 0.0017 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0085 0.1441 0.1441

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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