Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.9919 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.1472 | 0.1484 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0012 | 0.0468 | 0.0472 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0064 | 0.8997 | 0.8997 |
Echinococcus multilocularis | cysteine protease | 0.0018 | 0.1472 | 0.1484 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0018 | 0.1472 | 0.1484 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0012 | 0.0468 | 0.0472 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.1472 | 0.1484 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.9919 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0018 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0018 | 0.1472 | 0.1062 |
Onchocerca volvulus | Cathepsin L homolog | 0.0018 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0018 | 0.1472 | 0.1484 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.007 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.9919 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.1472 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0018 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0012 | 0.0468 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0012 | 0.0468 | 0.0472 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.9919 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0018 | 0.1472 | 0.5 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0055 | 0.7525 | 0.7525 |
Loa Loa (eye worm) | ctsf protein | 0.0018 | 0.1472 | 0.1062 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0018 | 0.1472 | 0.1062 |
Leishmania major | cathepsin L-like protease | 0.007 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.9919 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0018 | 0.1472 | 1 |
Onchocerca volvulus | 0.0018 | 0.1472 | 1 | |
Leishmania major | cathepsin L-like protease | 0.007 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0012 | 0.0468 | 0.0472 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0018 | 0.1472 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0018 | 0.1472 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0018 | 0.1472 | 0.1484 |
Onchocerca volvulus | 0.0018 | 0.1472 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.1472 | 0.1484 |
Brugia malayi | Cathepsin L-like precursor | 0.0012 | 0.0468 | 0.0472 |
Echinococcus multilocularis | cysteine protease | 0.0018 | 0.1472 | 0.1484 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0018 | 0.1472 | 0.1472 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.1472 | 0.1062 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.1472 | 0.1484 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0018 | 0.1472 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.007 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0018 | 0.1472 | 0.1062 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.9919 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.1472 | 0.1484 |
Entamoeba histolytica | cysteine protease, putative | 0.0018 | 0.1472 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0018 | 0.1472 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0018 | 0.1472 | 1 |
Onchocerca volvulus | 0.0018 | 0.1472 | 1 | |
Onchocerca volvulus | 0.0018 | 0.1472 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Onchocerca volvulus | 0.0018 | 0.1472 | 1 | |
Onchocerca volvulus | 0.0018 | 0.1472 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0069 | 0.9919 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0018 | 0.1472 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.007 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0018 | 0.1472 | 0.1062 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Plasmodium vivax | vivapain-2 | 0.0018 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.9919 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.9919 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.9919 | 1 |
Onchocerca volvulus | 0.0018 | 0.1472 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0018 | 0.1472 | 0.1484 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.007 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0018 | 0.1472 | 0.1484 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.9919 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0018 | 0.1472 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0018 | 0.1472 | 0.1484 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.9919 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0012 | 0.0468 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0018 | 0.1472 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0018 | 0.1472 | 1 |
Plasmodium vivax | vivapain-2 | 0.0018 | 0.1472 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0012 | 0.0468 | 0.3182 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.9919 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0012 | 0.0468 | 0.0472 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.